🍎 Food & Nutrition

Healthline Jul 20, 15:28

FDA OKs Lipfendra, a Groundbreaking New Pill to Lower Cholesterol

Lipfendra, a new once-daily pill for high cholesterol, can be taken instead of or alongside a statin. Iryna Veklich · Moment / Getty Images The FDA has approved Lipfendra, a new drug for adults with high LDL cholesterol. It is the first PCSK9 inhibitor in its class to come as a pill; the other three treatments require shots. Lipfendra can be taken instead of or alongside a statin to lower high LDL cholesterol. People with high cholesterol levels now have a new treatment option: a once-daily pill. The Food and Drug Administration (FDA) approved Lipfendra (enlicitide) on July 16 to lower low-density lipoprotein (LDL) cholesterol in adults with high cholesterol . LDL cholesterol — often called “bad” cholesterol — builds up in the arteries and raises the risk of heart attack, stroke, and artery diseases, according to the American Heart Association (AHA) . Most people who need cholesterol medication start with a statin, according to the AHA . However, statins don’t always do the job on their own . How well people tolerate statins varies from person to person, and the highest tolerated dose isn’t always enough to lower their cholesterol to a safe level. That’s where drugs like Lipfendra come in. Lipfendra can be used in addition to or instead of a statin to lower LDL through a different mechanism. The trials leading to Lipfendra’s approval tested the drug in individuals taking statins. The prescribing info for the drug states that this PCSK9 inhibitor can be used as an adjunct therapy to diet and exercise to lower LDL cholesterol in adults with high blood pressure . Here’s why experts say the new pill could revolutionize treatment. Lipfendra: A once-daily pill for ‘bad’ cholesterol As a daily pill, Lipfendra provides those with high cholesterol an alternative to needles. “Being able to have an oral version of this medication is really important,” said Yu-Ming Ni , MD, a cardiologist and lipidologist at MemorialCare Heart and Vascular Institute at Orange Coast Medical Center in Fountain Valley, CA. “I have a lot of people who are hesitant to even start because they don’t want to give themselves injections,” Ni told Healthline. “Now you’ve got this oral version. It’s going to be a little bit easier for people to take a pill every day.” Because Lipfendra works differently from a statin, people can use both medications. Anurag Mehta , MD, a preventive cardiologist at Emory Healthcare and assistant professor of medicine at Emory University School of Medicine, said the two drugs target “two different biological pathways” to reach “the same end result” — lower LDL cholesterol.  For individuals whose statin isn’t enough on its own, “those patients would be candidates for this new medicine,” Mehta said. Lipfendra lowers LDL levels by nearly 60% Lipfendra’s approval rests on two trials that together enrolled more than 3,200 adults already taking the highest statin dose they could tolerate, the FDA said in a release. After 24 weeks, the drug lowered LDL cholesterol by about 56% in the main study and 59% in a second study focused on people with an inherited form of high cholesterol. Ni called the reductions “quite impressive.” The trials measured how much Lipfendra lowers cholesterol, not whether it prevents heart attack and stroke . A larger trial testing that question is still underway. The FDA told Healthline it accepts a drop in LDL-C as a validated stand-in for lower cardiovascular risk . Ni noted the distinction but pointed to the broader evidence. “We have tons of data showing that the lower the cholesterol you go, the lower your risk for heart disease,” he said. In the first trial, side effects occurred about as often as with a placebo. In the second trial, patients most often reported diarrhea and dizziness, the FDA release said. Ni said he prescribed Lipfendra to his first patient the day after it became available. He said the patient was already on a statin and needed more help but wanted nothing to do with injections. “He’s like, ‘that sounds great, because I don’t want to do any injections,’” Ni recalled. Lipfendra vs. other cholesterol treatments Statins and Lipfendra lower LDL cholesterol by different routes, which is why a doctor can prescribe them together. Statins reduce the amount of cholesterol the liver produces, while Lipfendra helps the liver remove more cholesterol from the blood. It does this by blocking a protein called PCSK9 . Lipfendra is the fourth PCSK9 inhibitor to win FDA approval, and the first in pill form. The others are injections — evolocumab and alirocumab , typically given every two weeks at home, and inclisiran, administered twice a year in the clinic. All of them lower LDL cholesterol by 50% to 60%, according to patient data .  Mehta told Healthline that the choice comes down to personal preference. “What does the patient want?” Mehta said. “Are they comfortable with giving themselves an injection every two weeks? Do they want to come to the office and get a shot twice a year? Or ...

More: FDA OKs Lipfendra, a Groundbreaking New Pill to Lower Cholesterol. People with high cholesterol levels now have a new treatment option: a once-daily pill. The FDA told Healthline it accepts a drop in LDL-C as a validated stand-in for lower cardiovascular risk .

TL;DR: “We have tons of data showing that the lower the cholesterol you go, the lower your risk for heart disease,” he said.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 20, 15:28

U.S. Military to Screen for Low Testosterone. Why Experts Are Concerned

The U.S. military will begin screening service members for testosterone deficiency to “optimize” health. Getty Images Defense Secretary Pete Hegseth announced that the U.S. military will begin annual screening for testosterone deficiency among service members ages 30 and older. Testosterone replacement therapy (TRT) may benefit people with a confirmed deficiency, but there are risks, including impaired fertility. A single blood test cannot diagnose low testosterone; other symptoms must also be present. Defense Secretary Pete Hegseth announced that the U.S. military will begin screening service members ages 30 and older for testosterone deficiency as part of their annual health assessments. In a video posted on X , Hegseth framed the initiative as a way to “optimize” health and combat readiness. “Under the supervision of our world-class medical professionals, war fighters age 30 and older are going to be tested annually as part of their periodic health assessment,” Hegseth said. Service members under 30 will be able to request testing voluntarily. Those who are diagnosed with low testosterone may be offered testosterone replacement therapy (TRT) , although treatment is voluntary. Testosterone is an important sex hormone that helps regulate muscle mass, libido , mood, energy, and more. Levels tend to decline gradually with age, but low testosterone, which is clinically known as hypogonadism , can also result from a variety of factors, including injury, lifestyle, and disease. Hegseth said the program would help keep troops on the “leading edge of lethality” by supporting their physical and psychological readiness. However, experts interviewed by Healthline raised concerns about the program. “I do not believe routine testosterone screening of every service member beginning at age 30 is medically justified based on the evidence currently available,” said Philip Werthman , MD, board certified urologist, men’s health specialist, and director of the Center for Male Reproductive Medicine and Vasectomy Reversal in Los Angeles. S. Adam Ramin , MD, board certified urologist, urologic oncologist, and medical director of Urology Cancer Specialists in Los Angeles, similarly cautioned that a testosterone blood test may offer little useful information when performed in younger men who do not have symptoms. “In men who are not exhibiting clinical signs and symptoms of low testosterone , and are under the age of 40, checking a blood test testosterone level may not be informative or required from a medical standpoint,” he said. Why is the military testing for low testosterone? Under the new policy, testosterone deficiency screening will be incorporated into an annual health visit known as a periodic health assessment for service members ages 30 and older. Testing will be optional for younger service members. If additional evaluation confirms testosterone deficiency, an individual can elect to receive TRT. Hegseth has said the goal is not to push testosterone above its natural range or use the hormone as a performance-enhancing drug. Instead, he described the program as an effort to protect longevity and ensure “the biological foundation to sustain the fight.” However, the specifics of the program, including what the screening protocol would entail were not clear from the announcement. Experts say those specifics matter, since a single low testosterone reading from a blood test is not sufficient to diagnose testosterone deficiency. “Making a diagnosis is not based on just one test,” said Lawrence Jenkins , MD, Associate Chair of Urology & Director of Men’s Health at Tulane University School of Medicine. “It is based on two low levels plus symptoms. So, just doing one screening test is not going to meet any diagnosis criteria.” Testosterone levels fluctuate throughout the day and may also vary from one day to another. They are influenced by many lifestyle factors, including sleep, food intake, illness, medications, body weight, and physical activity. For military service members, the physical and psychological demands of training and deployment could temporarily suppress hormone levels. “An abnormal testosterone level obtained during deployment, sleep deprivation or severe training should not automatically lead to lifelong therapy. Repeat testing should generally occur after reversible factors have been addressed,” Werthman cautioned. Without a rigorous screening protocol, the program could potentially expose healthy service members to unnecessary treatment. But Ramin told Healthline that the right kind of screening, and not just relying on a blood test, might be appropriate. “If by testosterone screening we mean asking questions about symptoms of low testosterone and performing a physical exam , then the screening is indicated as part of a yearly men’s health examination,” Ramin said. “In patients who do exhibit symptoms or physical signs of low testosterone, then the blood test would be indicated.” TRT may impact fertility...

More: They are influenced by many lifestyle factors, including sleep, food intake, illness, medications, body weight, and physical activity. But Ramin told Healthline that the right kind of screening, and not just relying on a blood test, might be appropriate. “In patients who do exhibit symptoms or physical signs of low testosterone, then the blood test would be indicated.

TL;DR: military will begin screening service members for testosterone deficiency to “optimize” health.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jul 19, 08:27

How Going to the Movies and Museums May Help Slow Biological Aging

Research shows that regular cultural engagement can slow physiological aging in older adults. Image Credit: AzmanJaka/Getty A new study claims that older adults who regularly attend cultural events such as museums, movies, and theater tend to have a lower physiological age, meaning their bodies function younger than their years . Those who engaged culturally every few months or more had an average physiological age of about 3 years less than those with less participation, despite similar actual ages . There are various reasons cultural engagement may slow aging, including improved mental health. Cultural engagement, such as attending the cinema, theater, or a museum, has been shown to improve overall mental and social well-being in older adults . A study published on July 14 in the Journal of Epidemiology & Community Health has added to the extensive body of research showing how impactful participating in the arts can be for people’s overall health and may help them live longer. Researchers at the Institute of Science, Tokyo , found that older adults who remained culturally engaged tended to have a lower physiological age, also known as biological age . In other words, the more people participated in cultural activities like museums, theatre, or movies, the younger their bodies appeared to function. How cultural engagement slows physiological age The team analyzed data from people 50 and older living in England, using data from the English Longitudinal Study of Ageing . The study found people who took part in cultural activities at least once every few months had an average physiological age of about 66.9 years, compared with 69.9 years for those who engaged less often — a gap of roughly 3 years. Their actual ages were much closer together (68.7 versus 70.3), which means the more engaged group’s bodies were functioning younger than their birth dates would suggest. The researchers scored cultural engagement based on how often participants went to the cinema, museums or art galleries, and the theater, concerts, or the opera. The study identifies three ways cultural engagement might slow physiological aging: Strengthens social relationships  Cultural activities often bring people together, and that community interaction helps build social ties. According to a 2019 British study , people who regularly engage in these activities face a lower risk of loneliness over time. Promotes healthier habits The study’s authors note that people who engage in cultural events are more likely to eat well and be physically active. Improves mental health Cultural engagement can help reduce psychological distress and support better overall mental well-being, the researchers report. They add that lower stress and distress levels are directly tied to slower physiological aging. Still, the study’s authors caution that these findings don’t prove cause and effect and said further research is needed. They acknowledge the possibility of reverse causation, meaning people who are already healthier and aging more slowly may simply have more energy and ability to participate in cultural activities in the first place. The researchers said the most engaged people were more likely to be females, have higher incomes, be employed, and be in better health to begin with. What is physiological age? Physiological age (PA) measures how well someone’s body is functioning, rather than just counting the years since they were born. Two people can be the same age on paper, but their bodies might be aging at very different speeds depending on their health. To determine someone’s PA, researchers used a method that combines health measurements from five body systems into a score. Here’s what each system measures: Heart and blood vessels: blood and pulse pressure readings Lungs: how much air a person can breathe out in one breath Blood: oxygen-carrying protein levels and a clotting-related protein Metabolism: blood sugar levels and cholesterol Muscles and bones: weight relative to height, hand grip strength, and walking speed A higher physiological age is linked to a greater risk of disease and death. A 2025 study using data from the U.S. Health and Retirement Study , which tracks 20,000 people in America, found that physiological age predicts mortality in older adults more accurately than chronological age. Community arts programs improve health in older adults The findings align with research conducted in the United States. The 2006 “ Creativity and Aging Study ” found that community-based arts programs had “powerful positive intervention effects” on older adults’ health. Cultural institutions like the High Museum of Art in Atlanta create programming specifically for aging adults. Andrew Westover , the museum’s director of learning and civic engagement, said their Culture Collective programs are designed specifically for people 50 and over, “around the idea that people are always learning and growing.” “There [are] all of these ways that gathering at...

More: A study published on July 14 in the Journal of Epidemiology & Community Health has added to the extensive body of research showing how impactful participating in the arts can be for people’s overall health and may help them live longer. According to a 2019 British study , people who regularly engage in these activities face a lower risk of loneliness over time.

TL;DR: Research shows that regular cultural engagement can slow physiological aging in older adults.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jul 18, 12:30

‘Early Bird Dinner’: Does the TikTok Sleep Hack Actually Work?

A popular TikTok trend suggests that eating dinner 4 to 5 hours before bed can improve sleep quality. Image credit: Olga Rolenko · Moment/Getty “ Early-bird dinners” are a growing social media trend, with some TikTokers claiming that eating earlier can improve sleep quality. Experts agree that consuming the last meal of the day earlier in the evening may help with getting a better night’s rest. Eating dinner earlier may also offer additional benefits, such as reducing acid reflux and improving blood glucose levels. While early bird dinners are generally safe, experts advise that some people, such as those with diabetes, should consult a healthcare professional first. Influencers on TikTok and other social media platforms claim that eating dinner earlier can improve sleep quality and metabolic health. The trend claims that “early bird dinners,” which involve eating around 5:00 p.m. or 4 to 5 hours before bed, can help maximize deep sleep. Some proponents say that eating earlier may help reduce midnight cortisol spikes and eliminate morning acid reflux. But early bird dinners are not a new concept. The “early bird special” for those dining out before traditional hours has been around for decades. Does eating earlier have any real benefits for sleep or well-being? Healthline spoke with experts to learn more. Can early bird dinners improve sleep quality? The early-bird-dinner trend suggests that eating the last meal of the day around 4 to 5 hours before going to sleep may improve sleep quality for some people. Alex Dimitriu , MD, a double board-certified psychiatrist and sleep medicine specialist and founder of Menlo Park Psychiatry & Sleep Medicine, said that eating dinner earlier may offer some tangible benefits. “This is a rare case where a TikTok trend actually aligns with basic human biology,” Dimitriu said. “Eating earlier improves sleep by reducing digestion while asleep, and minimizing acid reflux , both of which can be disruptive to a good night’s sleep.” Sarathi Bhattacharyya , MD, a pulmonologist and sleep medicine specialist and the medical director of MemorialCare Sleep Disorders Center at Long Beach Medical Center in Long Beach, CA, noted that eating or drinking later can disrupt sleep. “Caffeinated beverages can also lead to nighttime awakenings, often for trips to the restroom,” he said. Bhattacharyya recommended avoiding eating and drinking, especially caffeine or alcohol, at least 3 hours before bed. Are there other benefits to early bird dinners? Eating dinner early is widely regarded as safe and beneficial for digestion. Studies have explored other potential benefits of early-bird dinners. A 2021 study found that eating dinner at 6 p.m. rather than 9 p.m. improved blood glucose levels and substrate oxidation. Substrate oxidation is the burning of substrates such as carbohydrates and fats to produce energy for the body. A 2023 review supports this by suggesting that going to bed soon after eating can lead to a prolonged rise in blood sugar levels , potentially due to disruption during the transition from daytime feeding to nocturnal fasting. Eating dinner earlier may help to avoid this. Another study from 2023 examined the potential benefits of an earlier dinner time for heart health. It found that there was a 28% higher risk of cerebrovascular disease in people who ate their last meal of the day after 9 p.m., compared with those who ate their last meal before 8 p.m. The study also found that delaying the first meal of the day was associated with a higher risk of cardiovascular disease . Some people who eat dinner late at night may be more likely to skip breakfast the following morning, which could therefore increase the risk of heart problems. Are there any downsides to eating dinner early? Eating your last meal 4 to 5 hours before bed is generally safe for most people, Dimitriu said. However, those with certain health conditions should consult with their doctor before making changes to their mealtimes. “People with diabetes or low blood sugar should consult a doctor first,” he said. “Heavy proteins disrupt sleep quality the most because they force the body to work when it should be resting. Alcohol markedly impacts sleep architecture, reducing deep sleep in the first half of the night and REM sleep in the morning, both essential to a good night’s rest,” Dmitriu explained. Other ways to improve sleep Many factors can affect sleep quality and duration. “Beyond timing, the most effective ways to improve sleep are maintaining a consistent schedule and keeping your bedroom cool, dark, and quiet,” said Dimitriu. “Darkness is especially hard to get in the summer months, so either get blackout shades or an eye mask,” he added. Bhattacharyya said that late-night eating and inappropriate light exposure in the period leading up to bedtime are among the most common factors that can affect sleep. “Light exposure can suppress the body’s natural sleep drive and make it harder to fall or stay asleep,” s...

More: A 2021 study found that eating dinner at 6 p.m. Another study from 2023 examined the potential benefits of an earlier dinner time for heart health. “People with diabetes or low blood sugar should consult a doctor first,” he said.

TL;DR: The study also found that delaying the first meal of the day was associated with a higher risk of cardiovascular disease .

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jul 17, 18:14

Why GLP-1 Drugs May Raise Muscle Loss, Frailty Risk for People Over 65

A new report states that older adults using GLP-1 drugs may have a higher risk of loss of muscle mass, malnutrition, dehydration, and other frailty-associated conditions. Getty Images A new report states that older adults using GLP-1 drugs may have a higher risk of loss of muscle mass, malnutrition, and dehydration. However, the benefits of taking these drugs should be weighed against these risks when the medications are prescribed. The researchers say that GLP-1 drugs benefit older adults by promoting weight loss, lowering blood sugar levels, and improving heart health. The authors of a new report are urging doctors to keep a closer watch on older adults taking GLP-1 medications for weight loss or type 2 diabetes. The report states that adults ages 65 and older have a higher risk of malnutrition, dehydration , and loss of muscle mass while taking GLP-1 drugs containing the active ingredient tirzepatide . However, the researchers noted that frailty-associated conditions are uncommon with GLP-1 use and should not discourage the appropriate use of this class of medications. GLP-1 drugs containing tirzepatide, such as Zepbound and Mounjaro , help promote weight management, blood sugar regulation , heart health , sleep apnea , and more. Instead, the researchers encouraged doctors to more closely follow up with older adults who are taking GLP-1 medications . “These conditions are rare occurrences, and we should just be more aware of the issues for older adults,” said Mir Ali , MD, a bariatric medicine specialist and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California. “By no means does it mean we should not prescribe these medications to people over 65,” he told Healthline. Tirzepatide raised risk of frailty conditions in older adults The research was conducted by nference , an artificial intelligence platform that collects data for healthcare research. The study is currently under peer review and has not yet been published in a scientific journal. One study cohort consisted of 30,000 U.S. adults age 65 and older who were prescribed Zepbound for obesity, Reuters reported. Another group contained nearly 19,000 older adults receiving non-GLP-1 drugs for type 2 diabetes . The third cohort involved nearly 6,000 participants who had undergone weight-loss surgery. The researchers reported that the health records of those subjects indicated that less than 1% overall experienced declines in muscle mass and function. Less than 2% overall developed malnutrition, and about 3% experienced dehydration. Almost 5% reported a loss of appetite. However, the researchers reported that the risks associated with these conditions were significantly higher among participants taking Zepbound. The researchers said Zepbound users who developed malnutrition had a 25-fold higher risk of related death than tirzepatide users who did not develop malnutrition during an 18-month follow-up period. By comparison, the risk of death from malnutrition was only 7-fold for people prescribed other diabetes treatments and two-fold for those who had weight-loss surgery. In addition, Zepbound users who experienced dehydration had a 6-fold higher death risk compared to a 4-fold higher risk among people given other treatments and a 2.5-fold higher risk for those who underwent surgery. Zepbound users who experienced muscle mass loss had a 12-fold higher risk of death compared to 6-fold higher risk in people using other medications and a 2-fold higher risk among surgery patients. The researchers noted that the frailty conditions tended to appear among the Zepbound group after 6 months of treatment, suggesting that close follow-up is important. “[This was a] well-designed study showing concerns for frailty is important because frailty in older age is also predictive of mortality,” said Kristin Kirkpatrick , RD, president of KAK Consulting and a dietitian at the Cleveland Clinic’s Department of Wellness & Preventive Medicine. “The study showed that risk was associated with level of weight loss while also highlighting other important factors such as malnutrition and dehydration. However, the paper did not show that tirzepatide was not safe and, as with many studies, limitations to the research did occur,” Kirkpatrick told Healthline. Kirkpatrick said the findings provide some caution for medical professionals when prescribing GLP-1 medications to older adults. “I think this depends on the individual… and healthcare providers must weigh the risk versus the benefits given the overall health, lab data, dietary history, and contraindications,” she explained. More older adults using GLP-1 drugs for weight loss The number of adults in the United States who are taking GLP-1 medications for weight loss has hit a record high of 11%, or around 40 million people. Adults 65 years and older who take weight-loss drugs also appear to be on the rise. For example, the number of Medicare Part D enrollees using Ozemp...

More: Why GLP-1 Drugs May Raise Muscle Loss, Frailty Risk for People Over 65. The researchers say that GLP-1 drugs benefit older adults by promoting weight loss, lowering blood sugar levels, and improving heart health. GLP-1 drugs containing tirzepatide, such as Zepbound and Mounjaro , help promote weight management, blood sugar regulation , heart health , sleep apnea , and more.

TL;DR: A new report states that older adults using GLP-1 drugs may have a higher risk of loss of muscle mass, malnutrition, dehydration, and other frailty-associated conditions.

Read original at Healthline →

Further reading: Nutrition.govPubMed NutritionWHO NutritionWikipedia

Healthline Jul 17, 16:50

GLP-1 Drugs Like Wegovy, Mounjaro May Help With Binge Eating Disorder

GLP-1 medications like Ozempic and Wegovy may help ease symptoms of binge eating disorder and related eating behaviors. Giselleflissak/Getty Images A new study found that GLP-1RAs could reduce key symptoms of binge eating disorder. These included binge eating severity, loss of control eating, and emotional eating. Experts say that GLP-1RAs could potentially augment existing BED treatments like psychotherapy. However, you should always consult with an eating disorder specialist before using them. Additional research will be needed to establish their effectiveness. New research published online on July 15, 2026, in eClinical Medicine , suggests that a class of medications originally designed to treat type 2 diabetes and aid weight loss may also help reduce binge eating behaviors in individuals living with obesity. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) like Ozempic and Wegovy have been widely prescribed for weight, but their potential to ease symptoms of binge eating disorder (BED) and related eating behaviors is now coming into clearer focus. The study found that GLP-1RAs can lead to moderate reductions in binge eating severity, loss of control eating, and emotional eating. However, these medications also appear to increase cognitive or dietary restraint, a form of conscious effort to control food intake. These findings offer hope for patients and healthcare providers seeking additional treatment options for binge eating symptoms, especially for people living with obesity . How the effect of GLP-1 drugs on binge eating disorder symptoms was studied To understand the effects of GLP-1RAs on binge eating behaviors, researchers undertook a systematic review and meta-analysis. This is a rigorous method that synthesizes evidence from multiple clinical trials to assess overall effectiveness. They searched major medical databases for randomized controlled trials (RCTs) published between 2005 and April 2026, the period during which GLP-1RAs have been in use. Trials were included if they compared any GLP-1RA medication to placebo or another active treatment and reported validated measures of binge eating or related eating behaviors, such as loss-of-control eating and disinhibited eating.  Studies involving participants with severe physical illnesses like cancer were excluded to maintain comparability. A total of 25 RCTs met the criteria, enrolling 8,069 participants, about two-thirds of whom were female and the majority of whom identified as white.  The median age was 47 years, and all participants were living with overweight or obesity. Only three studies specifically recruited individuals diagnosed with binge eating disorder, highlighting a current gap in targeted research. The most commonly studied GLP-1RA was liraglutide, followed by semaglutide, dulaglutide , tirzepatide, and several others.  The interventions varied in dosage and duration, ranging from 6 weeks to 104 weeks. Most studies used a placebo as the control treatment, though a few compared GLP-1RAs with other medications or behavioral therapies. Researchers extracted data on changes in binge eating severity, loss of control eating, disinhibited eating, emotional eating, and cognitive or dietary restraint. These outcomes were assessed using validated questionnaires, including the Binge Eating Scale (BES), Three-Factor Eating Questionnaire (TFEQ), and Control of Eating Questionnaire (CoEQ).  Statistical techniques were applied to calculate standardized mean differences, enabling comparison across studies with different scales. GLP-1 drugs may reduce binge eating symptoms and improve related eating behaviors The analysis revealed that participants who received GLP-1RAs experienced consistent and moderate reductions in core binge eating symptoms compared to those who received a placebo or other comparators. Specifically, there was a small-to-moderate decrease in binge eating severity, with effect sizes indicating meaningful improvements across multiple studies. Loss of control eating — a hallmark of binge episodes — was also significantly reduced. Participants reported fewer episodes of feeling unable to control their eating, suggesting that GLP-1RAs may help restore a sense of control over food intake. In addition to reductions in binge-related behaviors, emotional eating — a tendency to eat in response to negative emotions — was moderately decreased among those treated with GLP-1RAs. This is important because emotional eating often contributes to overeating and weight gain. Additionally, the medications were associated with an increase in cognitive or dietary restraint, meaning participants reported a greater conscious effort to limit food intake. While this could reflect healthier self-regulation, the authors say that in some cases, increased restraint may be linked to disordered eating behaviors. The effects were generally larger in trials that included individuals diagnosed with binge eating disorder or specifically aimed to redu...

More: GLP-1 Drugs Like Wegovy, Mounjaro May Help With Binge Eating Disorder. Giselleflissak/Getty Images A new study found that GLP-1RAs could reduce key symptoms of binge eating disorder. The study found that GLP-1RAs can lead to moderate reductions in binge eating severity, loss of control eating, and emotional eating.

TL;DR: GLP-1 medications like Ozempic and Wegovy may help ease symptoms of binge eating disorder and related eating behaviors.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jul 16, 08:20

What Is TikTok’s 3-Color Rule? How ‘Eating the Rainbow’ Can Boost Weight Loss

Following the “3-color rule” may help boost weight loss and improve overall health. Image Credit: fcafotodigital/Getty One of the newest nutritional trends on TikTok is the “3-color rule.” The “3-color rule” encourages people to include at least 3 different naturally colorful plant-based foods in each meal. Different pigments in food represent certain phytonutrients and vitamins. By aiming for at least three different colors in your meals, you can naturally balance your nutritional intake. This can provide many health benefits, including weight loss. From proteinmaxxing to fibermaxxing , TikTok is full of nutrition trends that promise to help people eat healthier. One of the latest is the “3-color rule,” which encourages people to include at least three naturally colorful plant-based foods in every meal — even something as simple as a sandwich. Also known as “ eating the rainbow, ” the concept itself isn’t new. But unlike many nutrition trends that gain traction on social media, this is one dietitians say can help people build a healthier, more balanced diet. “I like the “3 color rule” trend because it’s simple and encourages people to add more variety to their meals instead of focusing on counting calories or tracking macros. If thinking about three natural colors gets someone to eat more fruits and vegetables, that’s a positive step,” Michelle Routhenstein , preventive cardiology dietitian at Entirely Nourished, told Healthline. Experts say the approach may also support weight loss and provide a variety of other health benefits by making it easier to eat a wider range of nutrient-rich foods. How the ‘3-color rule’ can help with weight loss Research suggests that eating a wider variety of colorful fruits and vegetables may support healthy weight management. A 2022 review found that diets rich in colorful plant foods were associated with improvements in several obesity and heart disease-related risk factors, including: body mass index (BMI) waist circumference cholesterol “Including [at least] three different naturally colored plant foods at meals can increase plant‑based dietary diversity and intake of fiber, water, and bioactive compounds that support satiety and gut health,” said Routhenstein “This increases meal volume and nutrient density, making it easier to maintain an appropriate calorie intake without strict calorie counting to support weight loss and long‑term metabolic health.” Health benefits of the 3-color rule beyond weight loss The benefits of the 3-color rule go beyond weight loss. Different-colored fruits and vegetables contain different vitamins, minerals, and plant compounds called phytonutrients . Eating a wider variety of colorful foods can help ensure you’re getting a broader range of nutrients that support overall health. What do different food colors mean? Different colors tend to signal different beneficial nutrients. Here’s what each color group is known for: Red: Key nutrients are lycopene and vitamin C (examples: tomatoes, strawberries, red peppers) Orange and Yellow: Key nutrients are beta-carotene and vitamin A (examples: carrots, oranges, squash) Green: Key nutrients are folate , vitamin K , and fiber (examples: broccoli, spinach, green beans) Blue and purple: Key nutrients are antioxidants and anthocyanins (examples: blueberries, blackberries, eggplant) White and tan: Key nutrients are potassium and fiber (examples: onions, garlic, and cauliflower) “Color signifies nutrient density. The deeper the hue, the more benefit. This is why we see so many beneficial studies on foods like coffee, dark chocolate, berries, cruciferous veggies, leafy greens, tomatoes, cranberries, etc. They are full of color and thus full of phytonutrients,” said Kristin Kirkpatrick , a registered dietitian. Research suggests that focusing on colorful foods may also make healthy eating easier. Rather than tracking nutrients or calories, using color as a guide can help people naturally choose more nutritious foods. Over time, eating a wider variety of colorful plant foods may help: increase your fiber intake boost energy support heart health strengthen immunity improve digestion However, Routhenstein noted that “color alone doesn’t make a meal balanced. A meal can be colorful but still lack enough protein, fiber, or healthy fats, which are all important for heart health, blood sugar balance, weight management, nutrient adequacy, and satiety.” How to follow the 3-color rule at every meal Experts say the easiest way to follow the 3-color rule is to keep it simple. Rather than overthinking every meal, focus on gradually adding more colorful plant foods throughout the day. “Know that color comes from plants only, so the more plants you consume, the more color you get,” Kirkpatrick said. Kirkpatrick recommends looking for simple ways to add more color to meals you already enjoy. For example, you can try: adding berries to oatmeal in the morning to incorporate two or three colors adding tomatoes and c...

More: This can provide many health benefits, including weight loss. Experts say the approach may also support weight loss and provide a variety of other health benefits by making it easier to eat a wider range of nutrient-rich foods. Research suggests that focusing on colorful foods may also make healthy eating easier.

TL;DR: Following the “3-color rule” may help boost weight loss and improve overall health.

Read original at Healthline →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Bbc Jul 16, 00:20

Jesy Nelson calls plan to test newborns for deadly muscle condition a 'victory'

All newborn babies in England will be tested for the genetic disease spinal muscular atrophy (SMA), as part of a major study.

More: All newborn babies in England will be tested for the genetic disease spinal muscular atrophy (SMA), as part of a major study. SMA causes muscle weakness. This affects movement such as the ability to walk, but it also affects the muscles needed to breathe and to swallow.

TL;DR: All newborn babies are set to have a heel prick test for Spinal Muscular Atrophy (SMA) in England.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jul 15, 18:27

What Are ‘Ozempic Feet?’ Doctors Explain Latest GLP-1 Side Effect From Weight Loss

Some people using GLP-1 drugs for weight loss have reported changes in their feet. Image Credit: stockvisual/Getty “Ozempic feet” is the latest anecdotal side effect of GLP-1 drugs for weight loss. The unusual phenomenon is a result of rapid weight loss, which may cause foot pain, changes in shoe size, and a more bony appearance in the feet. “Ozempic feet” is not listed as a common side effect of Ozempic, Wegovy, or other GLP-1 drugs. Many people taking GLP-1 drugs for weight loss have reported strange side effects, ranging from “ Ozempic butt ” to “ Ozempic face ” and “ Ozempic breasts .”  These effects are often attributed to the rapid weight loss that comes with GLP-1 use, with the latest side effect causing unusual changes to the feet. Anecdotal reports of “Ozempic feet” describe a more bony, loose, and deflated appearance in their lower extremities. The phenomenon may also involve pain, aching, and a burning sensation in the feet.  Some people who’ve experienced dramatic weight loss with GLP-1s like Ozempic and Wegovy say the effects are more noticeable on the tops of their feet, where tendons and veins are more prominent.  Despite the claims, “Ozempic feet” is not listed among the common side effects of GLP-1 medications .  ‘Ozempic feet‘ likely caused by rapid weight loss Experts say that “Ozempic feet” is not a direct side effect of the medication but rather a result of significant weight loss. “We see similar changes in our surgical weight loss patients. It is essentially a change in the appearance of the feet; as fat and muscle are lost, the skin may appear looser or wrinklier, and a patient’s shoe size may decrease,” Mir Ali , MD, medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, told Healthline.  Common effects of “Ozempic feet” fall into different categories:  Aesthetic: The skin on top of the foot may look loose, wrinkled, or saggy. Veins and tendons may become more prominent. Functional pain: Aching or burning in the balls of the feet, or new heel pain. Some people describe it as “walking on pebbles.” Shoe fit issues: Shoes that used to fit perfectly may begin to feel too big. Some people have reported dropping an entire shoe size, some have gone from a wide foot to a regular or narrow foot. There are various reasons why people may experience “Ozempic feet.” Here are a few of them. Fat pad atrophy Fat pad atrophy is the thinning of the plantar fat pad. This is the layer of soft tissue between the skin and the heel bone that cushions and supports the heel. When you lose weight rapidly, it can thin the plantar fat pad and lead to heel pain, especially when walking or running.  Muscle loss In addition to fat loss, GLP-1s may lead to loss of lean mass , including muscle. A 2024 systematic review and meta-analysis found that nearly 31% of total body weight loss with GLP-1 drugs is lean mass.  However, a recent study found that GLP-1s may not always lead to disproportionate muscle loss, particularly among those who engage in regular strength training.  If muscle loss occurs, it can significantly affect your feet. Tiny muscles in the feet support the arches and help to maintain stability. If these shrink during rapid weight loss, it can change how the arches flatten and affect gait. If calf muscles decrease in mass, it may affect the Achilles tendon and ankle stability. Structural changes The structure of the foot adapts when excess weight is carried for long periods. This may include flattening the arches, stretching the plantar fascia, and compressing the fat pads.  When you lose a lot of weight, especially quickly, these structures don’t necessarily snap back to their original form right away. The changes may occur gradually. Tips to manage ‘Ozempic feet’ Ali said that adequate protein intake and regular exercise can help reduce muscle loss.  “[However], these changes in the appearance of the feet cannot be entirely prevented during significant weight loss,” he said. To manage the changes in your feet, you can also: reassess your shoe size add cushioning or change to shoes with more cushion strength train your whole body, including your feet moisturize the skin regularly check your feet daily if you have diabetes “There are also collagen-enhancing therapies that help improve skin firmness. It is very important to discuss this concern with your healthcare provider during the initial consultation of GLP-1 therapy because preventive strategies are an effective way to avoid these complications,” Jonathan Jennings , MD, board certified internist with Medical Offices of Manhattan, told Healthline.  Ali emphasized that this is not a direct side effect of the medication itself, but a physiological change that can occur with any significant weight loss. “Although changes in the appearance of the feet and other areas of the body are common with major weight loss, I rarely see this as a primary concern for patients. The improvements...

More: What Are ‘Ozempic Feet?’ Doctors Explain Latest GLP-1 Side Effect From Weight Loss. Image Credit: stockvisual/Getty “Ozempic feet” is the latest anecdotal side effect of GLP-1 drugs for weight loss. When you lose weight rapidly, it can thin the plantar fat pad and lead to heel pain, especially when walking or running.

TL;DR: Some people using GLP-1 drugs for weight loss have reported changes in their feet.

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jul 15, 15:18

Depo-Provera, Other Hormonal Contraceptives Linked to Brain Tumors

Research shows that certain types of birth control, particularly those high in progestogen, may raise the risk of brain tumors. Image Credit: Pekic/Getty A new study revealed a link between certain progestogen contraceptives, including Depo-Provera, and a higher risk of meningioma brain tumors. Meningiomas are brain tumors that are typically benign (noncancerous). The overall risk is low, but it may be higher with prolonged use of specific products like Depo-Provera, which includes safety warnings from the FDA. The increased risk was found to be temporary and shouldn’t deter most people from using birth control. Many people rely on hormonal birth control primarily to prevent pregnancy. Hormonal contraceptives range from oral medications to intrauterine devices (IUDs) to injections and implants.  Recent data from the Centers for Disease Control and Prevention (CDC) show that 54.3% of females in the United States ages 15 to 49 used some form of contraception between 2022 and 2023. The World Health Organization (WHO) states that in 2021, 874 million females worldwide used modern contraceptive methods.  While birth control is largely regarded as safe, it may also come with certain health risks. A new study published on July 2 in JAMA Network Open found that certain common types of progesterone birth control may raise the risk of developing a meningioma.  Meningiomas are the most common type of brain tumor affecting the central nervous system, accounting for 37.6% of cases. Around 90% of meningiomas are benign (noncancerous) .  Meningiomas occur more often in females than in males, which may be due to the role that hormones play in their development. Hormonal contraceptives that include progesterone and progestin may contribute to the higher levels of these tumors in females. Which birth control has the highest brain tumor risk?  The study included 1,473 females with a meningioma and 14,717 as a control group who didn’t have the tumor. The participants all held residence in Denmark and had an average age of 48. For each participant with a meningioma, the researchers selected 10 female controls who were similar in age, birthplace, and marital status, and who didn’t have the tumor. This allowed the researchers to focus on the factor they were studying, rather than being influenced by unrelated differences between the groups. The study found that individuals who were using injectable medroxyprogesterone ( Depo-Provera ) were found to have the highest risk for a meningioma. This group was 4.6 times more likely to develop a tumor.  IUDs with high levels of levonorgestrel were shown to increase the risk of developing a tumor by 1.58. For IUDs with a lower levonorgestrel dose, this risk was slightly lower. Those using progesterone-only oral birth control were 1.7 times more likely to develop a meningioma. However, combination pills containing both estrogen and progesterone showed a slightly lower risk, with participants having 1.61 times the risk of developing a meningioma. The study authors noted that their findings suggest “an increased risk of meningioma for several progestogens not previously associated with meningioma.” The increased risk was highest in those who were currently using birth control and those who had used it within the past year. However, within 5 years after discontinuation of use, the increased risk was no longer present with most types of birth control. “These findings are considered relevant information for the treated women and the prescribing physicians,” the study authors stated. What’s the link between meningiomas and hormones? The study authors suggest that the consistently higher numbers of meningiomas among females support a hormonal role in the development of the tumors. This plausibility is supported by the presence of progesterone receptors in 87% of all meningiomas. There have also been clinical observations that showed tumor growth during pregnancy and during exogenous progestogen therapy. The tumor then regressed following the delivery or the withdrawal of treatment.  Safety warnings for hormonal contraceptives In 2025, the Food and Drug Administration (FDA) approved new label warnings for Depo-Provera. The warnings include the mention of meningioma and recommend discontinuation of the medication if this occurs.  The European Medicines Agency (EMA) also updated its recommendations for the use of certain medications containing synthetic progestins , such as nomegestrol and chlormadinone. These medications are typically used as part of hormone therapy for menopause and to treat conditions like endometriosis. The EMA has recommended that high doses of these medications should be used only when absolutely necessary, for a short period of time. They should also only be used when other interventions are not appropriate. The EMA states that people using these medications should be closely monitored for signs of meningioma, including:  vison changes hearing loss or ringing in th...

More: The increased risk was found to be temporary and shouldn’t deter most people from using birth control. The study found that individuals who were using injectable medroxyprogesterone ( Depo-Provera ) were found to have the highest risk for a meningioma. For IUDs with a lower levonorgestrel dose, this risk was slightly lower.

TL;DR: Research shows that certain types of birth control, particularly those high in progestogen, may raise the risk of brain tumors.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Bbc Jul 15, 13:46

What in the World

Close menu Episode details World Service , · 15 Jul 2026 , · 9 mins ADHD is a condition that causes difficulties with things like concentrating, regulating emotions and sitting still.

More: And many young women living with ADHD say their symptoms worsen during specific periods of their menstrual cycle. They’re asking around 50 women who have ADHD and are taking medication for it to track their menstrual cycle and the impact it has on their ADHD symptoms, and daily life more broadly.

TL;DR: A first of its kind study is looking at the link between ADHD and hormonal changes

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jul 15, 00:21

Longevity ‘Guru’ Bryan Johnson Reveals Autoimmune Gastritis Diagnosis: Early Signs, Symptoms

Healthline Health Conditions Health Conditions All Breast Cancer Cancer Care Caregiving for Alzheimer's Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease (COPD) Digestive Health Ey…

More: Longevity ‘Guru’ Bryan Johnson Reveals Autoimmune Gastritis Diagnosis: Early Signs, Symptoms. Featured Health News All Medicare 2026 Changes Can 6-6-6 Walking Workout Help You Lose Weight? Chromosomes, Genetics, and Your Health Top Reads Best Multivitamins for Women Best Multivitamins for Men Best Online Therapy Services Online Therapy That Takes Insurance Buy Ozempic Online M…

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jul 13, 22:51

‘Jurassic Park’ Star Sam Neill Dies at 78 After Remission from Rare Blood Cancer

SITGES, SPAIN – OCTOBER 11: Actor Sam Neill attends a press conference during day 9 of the 52nd edition of the Sitges Fantastic Film Festival on October 11, 2019 in Sitges, Spain. (Photo by Borja B. Hojas/Getty Images) Actor Sam O’Neill has died suddenly and unexpectedly at the age of 78, his family announced. O’Neill has been treated for the past 4 years for angioimmunoblastic T-cell lymphoma, a rare fast-growing type of blood cancer. No cause of death has been released, but O’Neill’s family said the star of the 1993 film Jurassic Park was cancer-free when he died. Actor Sam O’Neill has died following a 4-year battle with a rare, aggressive form of cancer that can be difficult to diagnose and treat, angioimmunoblastic T-cell lymphoma. O’Neill’s family announced that the 78-year-old actor had died suddenly and unexpectedly on Monday. No cause of death was given, but family members said O’Neill was believed to be cancer-free when he died in Sydney, Australia. In 2022, O’Neill, best-known for his role in the Jurassic Park film franchise, was diagnosed with angioimmunoblastic T-cell lymphoma , a rare type of blood cancer that affects white blood cells known as T-cells. The fast-growing blood cancer can spread to the lungs, liver, or bone marrow. In his memoir, “Did I Ever Tell You This?”, O’Neill wrote that doctors had initially diagnosed some swollen glands in his neck as “undetected COVID.” Eventually, a PET scan revealed O’Neill had the rare lymphoma. O’Neill underwent four rounds of chemotherapy. In late 2023, he announced on Instagram that his cancer had been in remission for 8 months. In a later interview , he added that he still required infusions every 2 weeks. In an  April 2026 interview , O’Neill said he was cancer-free. He added he had also been treated with  CAR-T cell therapy , a type of immunotherapy treatment that genetically changes the body’s immune cells so they can fight cancer. AITL is a rare cancer that is deadly and difficult to treat Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive form of peripheral T-cell lymphoma (PTCL). AITL accounts for 20% to 30% of all PTCL cases. The median age for diagnosis of AITL is 65 years. Symptoms from AITL include fatigue, high fever, night sweats, and skin rash. The symptoms can sometimes be similar to autoimmune diseases. Diagnosis requires a biopsy of tumor tissue. Additional exams such as blood tests, CT scans, bone marrow biopsies, and PET scans may also be used. AITL affects immune-regulating cells, so it can cause immune system malfunction as well as tumor growth. The exact cause of AITL isn’t known, but it can be driven by genetic mutations in stem cells as well as secondary mutations in genes that regulate how DNA is used. Many AITL cases involve the Epstein-Barr virus , which can infect non-cancerous cells that surround the AITL-affected T cells. Swaminthan Iyer , MD, a professor of lymphoma-myeloma at the UT MD Anderson Cancer Center in Texas, said AITL presents many challenges. “Angioimmunoblastic T‑cell lymphoma (AITL) can be a challenging disease to diagnose and treat,” he told Healthline. “AITL can go undiagnosed for some time,” Iyer explained. “In many cases, the disease presents with non-specific symptoms such as skin rash, diarrhea, weight loss, and swelling of the lymph nodes. Because these symptoms are not unique to AITL, the diagnosis can be difficult to pinpoint.” “In addition, the biopsies themselves can be challenging to interpret and often require expert histopathology to confirm the diagnosis,” he added. “As a result, time may sometimes be lost navigating the diagnostic process and ruling out other conditions.” Iyer noted that initial treatments can help control the disease for 12 to 15 months. “However, the lymphoma almost always recurs and requires additional treatment,” he noted. Iyer added that there are clinical trials that are exploring “novel therapeutic pathways” in which patients can be enrolled.

More: ‘Jurassic Park’ Star Sam Neill Dies at 78 After Remission from Rare Blood Cancer. O’Neill has been treated for the past 4 years for angioimmunoblastic T-cell lymphoma, a rare fast-growing type of blood cancer. The fast-growing blood cancer can spread to the lungs, liver, or bone marrow.

TL;DR: “In many cases, the disease presents with non-specific symptoms such as skin rash, diarrhea, weight loss, and swelling of the lymph nodes.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 13, 21:05

Almost Half of Dementia Cases Could Be Prevented: 14 Factors That Can Increase Your Risk

Experts say addressing modifiable risk factors may help lower your risk of dementia. Getty Images Millions of people around the world are living with cognitive impairment associated with dementia. However, nearly half of dementia cases could potentially be prevented by addressing 14 risk factors. Experts say it’s important to address all these factors, as they work together to influence risk. The World Health Organization (WHO) explains that as of 2021, 57 million people worldwide were living with dementia. This condition, which impairs memory, thinking, and daily functioning, can be caused by various diseases that damage the brain. Alzheimer’s disease is the most common form of dementia , accounting for 60%-70% of cases. According to a 2024 report from The Lancet Commissions , almost half (45%) of dementia cases could potentially be prevented. The document also identifies 14 modifiable risk factors that can contribute to dementia prevention, including various behaviors, medical conditions, and social and environmental factors. Knowing these risk factors is an important step. However, a new study published on June 30, 2026, in The Lancet Healthy Longevity , suggests that there is a gap between people knowing how to prevent dementia and actually putting those principles into practice. The authors note that while awareness campaigns can reach a large number of people, these efforts don’t tend to be particularly effective in motivating them. Interactive approaches led by trusted community members appear to be the most effective way to elicit change. Knowing your dementia risk factors is the first step in changing them To help highlight the biggest modifiable risk factors, Healthline spoke with Laura Bojarskaite , PhD, a neuroscientist and sleep researcher at the University of Oslo. Bojarskaite, who was not involved in the report or the study, told Healthline that the research highlights “an important but often misunderstood message.” Nearly half of dementia cases may be due to 14 risk factors, which people can often address with lifestyle changes. They include: Early-life low education “Education likely builds cognitive reserve, giving the brain greater resilience against age-related pathology,” she said. “Lifelong learning and cognitively stimulating activities may help maintain this reserve.” Midlife hearing loss Bojarskaite said that hearing loss can increase cognitive load, reduce social engagement, and accelerate brain atrophy. “Early hearing assessment and appropriate hearing aids are important interventions,” she said. High LDL cholesterol “Elevated LDL contributes to vascular disease and may impair blood flow to the brain, increasing the risk of both vascular dementia and Alzheimer’s disease,” she said. Diet, exercise, and medication as needed are important interventions. Depression Pointing to the association between chronic stress , inflammation, sleep disruption, and changes in the brain’s hippocampus, Bojarskaite said early recognition and treatment are essential when it comes to depression. Traumatic brain injury “Head injuries can trigger long-lasting neuroinflammation and increase the accumulation of pathological proteins linked to neurodegeneration,” she explained. Preventive measures include steps such as sports safety and fall prevention . Hypertension “ High blood pressure damages blood vessels throughout the body, including the brain, impairing blood flow and increasing the risk of vascular injury and dementia,” said Bojarskaite. The Alzheimer’s Society states that maintaining a healthy weight, exercising, limiting salt intake , reducing caffeine intake, limiting alcohol, and quitting smoking can all help manage blood pressure. There are also effective medications available. Physical inactivity “Exercise is one of the most powerful brain-health interventions we know,” Bojarskaite said. “Physical activity improves cardiovascular health, promotes neuroplasticity , and supports the growth and survival of neurons.” Diabetes “Chronically elevated blood glucose damages blood vessels and may impair insulin signaling in the brain, processes that have been linked to cognitive decline and dementia risk,” she said. The International Diabetes Federation notes the importance of managing your blood sugar if you have diabetes. They further state that certain diabetes medications may reduce dementia risk. Smoking “Smoking increases oxidative stress, inflammation, and vascular damage, all of which negatively affect brain aging,” Bojarskaite said. Quitting smoking can help reduce your risk. Obesity Maintaining a healthy weight is also an important step. “Obesity is associated with metabolic dysfunction, inflammation, and increased risk of cardiovascular disease and diabetes, which in turn affect brain health,” she explained. Excessive alcohol consumption It’s also essential to moderate your alcohol intake. “High alcohol intake can damage neurons directly, disrupt sleep, and contribute to nutritional defic...

More: Almost Half of Dementia Cases Could Be Prevented: 14 Factors That Can Increase Your Risk. Obesity Maintaining a healthy weight is also an important step. “Obesity is associated with metabolic dysfunction, inflammation, and increased risk of cardiovascular disease and diabetes, which in turn affect brain health,” she explained.

TL;DR: Experts say addressing modifiable risk factors may help lower your risk of dementia.

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jul 12, 17:41

Senator Lindsey Graham Dies at 71 Following ‘Brief and Sudden Illness’

WASHINGTON, DC – APRIL 27: U.S. Sen. Lindsey Graham (R-SC) speaks during a press conference at the U.S. Capitol on April 27, 2026, in Washington, DC. Republican senators gathered to introduce legislation to fund construction of a White House ballroom as a secure alternative event space following the shooting at the White House Correspondents’ Association dinner in Washington, DC Saturday night. (Photo by Heather Diehl/Getty Images) Sen. Lindsey Graham died Saturday at age 71 after a “brief and sudden illness,” according to his office. Reports indicate emergency responders were called to Graham’s home during a medical emergency involving cardiac arrest. Officials have not confirmed Graham’s cause of death. U.S. Senator Lindsey Graham, a Republican from South Carolina, has died at age 71. In a statement released Sunday, Graham’s office said: “It is with profound sadness that we announce the passing of United States Senator Lindsey Graham. Senator Graham passed away peacefully Saturday evening following a brief and sudden illness. We ask that you keep his family, friends, and staff in your thoughts during this difficult time and respect their privacy.” The statement did not identify a specific cause of death. NBC News further reported that emergency responders were dispatched to Graham’s Washington, D.C., residence Saturday night during a medical emergency that involved cardiac arrest, citing police dispatch audio the outlet obtained. The Wall Street Journal, which independently reviewed the dispatch audio, reported that responders were initially dispatched for chest pains before the incident escalated to cardiac arrest. According to the dispatch audio, emergency crews forced entry into the home before beginning CPR. Officials have not confirmed Graham’s cause of death. Graham has represented South Carolina in the U.S. Senate since 2003. How cardiac arrest is different from a heart attack The reports have prompted questions about what cardiac arrest is and how it differs from a heart attack. Cardiac arrest occurs when the heart suddenly stops beating effectively, preventing blood from circulating to the brain and other organs. It differs from a heart attack , which occurs when blood flow to the heart muscle is blocked. Although a heart attack can sometimes lead to cardiac arrest, the two conditions are not the same. Editor’s note :  This is a developing story. Healthline will update this article as additional information becomes available.

More: How cardiac arrest is different from a heart attack The reports have prompted questions about what cardiac arrest is and how it differs from a heart attack. Cardiac arrest occurs when the heart suddenly stops beating effectively, preventing blood from circulating to the brain and other organs.

TL;DR: It differs from a heart attack , which occurs when blood flow to the heart muscle is blocked.

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jul 11, 08:17

These Overlooked Skin Cancer Signs Could Be Easy to Miss

Many early signs of skin cancer can be easily overlooked. Image Credit: MoMo Productions/Getty Changes in moles aren’t the only early warning signs of skin cancer. Persistent sores, scaly patches, and other subtle skin changes can also be signs of the disease. Skin cancer is highly treatable when detected early, making it important to recognize overlooked warning signs and seek medical evaluation for concerning changes. Skin cancer is the most common cancer in the United States, accounting for an estimated 6.1 million cases each year. While the disease is highly preventable and often highly treatable when caught early, many people don’t recognize its earliest warning signs. Although changes in existing moles are among the best-known signs of skin cancer, the disease can also appear in less obvious ways. Persistent sores, scaly patches, and other subtle skin changes are often overlooked or mistaken for less serious conditions, delaying diagnosis and treatment. Healthline spoke to Paul Banwell , an internationally trained plastic surgeon and skin cancer specialist from the United Kingdom, and Tanya Evans , MD, a board certified dermatologist and medical director of the Skin Cancer Program at the Melanoma Clinic at MemorialCare Saddleback Medical Center in Laguna Hills, about commonly overlooked signs of skin cancer and the best ways to protect yourself from the sun.  This interview has been lightly edited for clarity and length. What are the most commonly overlooked signs of skin cancer? Banwell: One of the most commonly overlooked signs is a sore or patch of skin that simply doesn’t heal after several weeks. You should also be mindful of persistent scaly patches, shiny or pearly bumps, lesions that repeatedly bleed or crust over, or any new mark that continues to change. These can easily be mistaken for dry skin, eczema , or a minor injury, which is why they’re often ignored. When it comes to moles, it’s important to know what is normal for your own skin. Rather than comparing yourself to someone else, get into the habit of checking your skin regularly so you’re more likely to notice any changes. A mole that becomes larger, changes shape, develops uneven borders, alters in color, or starts itching, bleeding, or becoming tender should always be assessed. One of the most important warning signs is simply evolution – if something is changing over time, it’s worth getting it checked. Evans: A powerful yet underutilized screening tool is the “ugly duckling” sign. This is a mole that simply looks different from all surrounding moles (nevi), even if it does not meet ABCDE criteria, is an independent predictor of melanoma. What are the best ways people should protect themselves from the sun and reduce their skin cancer risk? Banwell: Protecting yourself from the sun doesn’t mean avoiding it altogether, but it does mean being sensible. I recommend using a broad-spectrum sunscreen with at least SPF 30 every day, and SPF 50 if you’re spending extended periods outdoors. Sunscreen should be applied generously and reapplied every 2 hours, or more often if you’ve been swimming or sweating. Just as importantly, combine sunscreen with other forms of protection , including seeking shade during the hottest part of the day, wearing a wide-brimmed hat, UV-protective sunglasses , and clothing that covers exposed skin. The biggest way to reduce your risk of skin cancer is to avoid repeated sunburn , particularly during childhood and adolescence, as this significantly increases the risk later in life. I also encourage everyone to carry out a quick skin check once a month. It only takes a few minutes and can help you spot changes early, when treatment is generally simpler and far more successful. Ultimately, skin cancer is highly treatable when it’s caught early. My advice is always the same: if you notice a new lesion, a changing mole, or any area of skin that doesn’t look or feel quite right, don’t ignore it or hope it will go away. Getting it checked promptly could make all the difference. Evans: UV exposure occurs on overcast days and is amplified by reflection off water, snow, and sand — protection should not be limited to sunny days. It is also important to wear lip balm with SPF 50 or greater. The lips have minimal protective melanin pigment. Reapply the lip balm every 1-2 hours or after meals. Another prevention method is to avoid indoor tanning. More than 10 tanning sessions are associated with a 34% increased risk of melanoma . Also, avoid excess UV lamps for nail lacquer processing at nail salons, as skin cancer can develop around the nail bed for both toenails and fingernails. What are common areas of the body that are often overlooked and forgotten regarding sun protection? Banwell: There are also several areas people routinely forget when applying sunscreen. The ears, back of the neck, scalp, lips, tops of the feet, and backs of the hands are particularly vulnerable because they’re regularly exposed but ...

More: These Overlooked Skin Cancer Signs Could Be Easy to Miss. What are the most commonly overlooked signs of skin cancer? The biggest way to reduce your risk of skin cancer is to avoid repeated sunburn , particularly during childhood and adolescence, as this significantly increases the risk later in life.

TL;DR: What are the best ways people should protect themselves from the sun and reduce their skin cancer risk?

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Bbc Jul 11, 03:03

People in 50s urged to complete bowel cancer screening

Health officials warn little over half of 54-year-olds completed free at-home test kits.

More: People in 50s urged to complete bowel cancer screening. Health officials warn little over half of 54-year-olds completed free at-home test kits.

TL;DR: Health officials warn little over half of 54-year-olds completed free at-home test kits.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jul 10, 18:31

Most Weight-Loss Drugs Do Not Improve Quality of Life or Heart Health

A new study found that while several newer weight loss medications can help with significant weight loss, they do not improve quality of life or boost long-term heart health. Getty Images A new study found that several newer medications can aid in significant weight loss. However, the most effective drugs produced more side effects, often leading people to quit. Experts say the lesson here is to look beyond weight loss. Patients need effective strategies for managing side effects. In recent years, the number of highly effective medications for the treatment of obesity has grown rapidly. In addition to helping people lose weight, these drugs can also help reduce heart disease risk as well as improve other obesity-related conditions like type 2 diabetes and sleep apnea . However, as the number of new drugs increases, physicians must now choose the right obesity treatment for each patient, balancing benefits and adverse effects. A comprehensive new study has evaluated the effectiveness and safety of medications designed to aid weight loss for adults who are living with overweight or obesity.  The analysis, published on July 8, 2026, in The BMJ , sheds light on which drugs produce the greatest weight loss, their potential side effects, and their impact on health outcomes such as heart disease and quality of life.  This information aims to help patients, doctors, and policymakers make informed decisions about obesity treatments. How researchers compared weight loss drugs to each other Researchers conducted a systematic review and network meta-analysis, a method that allows comparison of multiple treatments even when they haven’t been directly tested against each other. The study included randomized controlled trials lasting at least 12 weeks, involving adults with overweight or obesity, with or without related health issues like diabetes or heart disease. Altogether, nearly 100,000 participants were enrolled across 262 clinical trials. The trials compared 19 weight-loss drugs with lifestyle changes alone, placebo, or other medications. Data were collected from major medical databases through November 2025, including MEDLINE, EMBASE, and the Cochrane Library.  The researchers looked at 24 outcomes, including percentage of body weight lost, changes in waist circumference, changes in fat and muscle mass, side effects (including gastrointestinal symptoms and fatigue), rates of discontinuing treatment due to adverse events, and serious health outcomes such as heart attacks and death. They also examined factors such as trial duration, drug dosage, and patient characteristics to determine how they might affect results. The most effective drugs also had the most side effects The researchers found that two medications stood out for producing the greatest reductions in body weight after one year: tirzepatide and cagrilinitide-semaglutide . Both led to about 15% weight loss. Other drugs with meaningful effects included oral semaglutide, orforglipron , subcutaneous semaglutide, and phentermine-topiramate, which helped participants lose between 8% and 11% of their body weight. Emerging treatments like ecnoglutide, mazdutide, and retatrutide also showed promise for significant weight loss, though evidence for these newer drugs is still limited. The study also highlighted that greater weight loss often came with increased side effects, such as nausea, diarrhea, and fatigue, which sometimes led to patients stopping their medication. Drugs like orforglipron and naltrexone-bupropion had the highest rates of discontinuation due to adverse events. Another important finding was the loss of lean mass, particularly with tirzepatide and subcutaneous semaglutide. While these drugs reduced fat mass effectively, they also caused an average lean mass loss of 6% to 8%, which could affect muscle strength and overall health, especially in older adults . In terms of serious health outcomes, subcutaneous semaglutide was the only drug linked with lower risks of death from any cause and heart attacks. Both subcutaneous semaglutide and tirzepatide reduced the risk of heart failure , with tirzepatide also lowering hospital admissions for heart failure. No drug convincingly reduced the risk of kidney failure. Despite these health benefits and weight loss, none of the drugs showed meaningful improvements in quality of life scores after one year, suggesting that weight loss alone may not translate to better overall well-being in the short term. The study also found that longer treatment duration, especially beyond a year, was associated with larger weight reductions for subcutaneous semaglutide. However, other patient factors, such as diabetes status or baseline obesity severity, did not significantly affect drug effectiveness. Overall, the research suggests a trade-off: the most effective weight-loss drugs tend to have more side effects and higher rates of treatment discontinuation.  This information is vital for patients and healthcare provider...

More: Most Weight-Loss Drugs Do Not Improve Quality of Life or Heart Health. In addition to helping people lose weight, these drugs can also help reduce heart disease risk as well as improve other obesity-related conditions like type 2 diabetes and sleep apnea . Both led to about 15% weight loss.

TL;DR: A new study found that while several newer weight loss medications can help with significant weight loss, they do not improve quality of life or boost long-term heart health.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 9, 17:54

Sniffing Chocolate Could Boost Your Leg Day Workouts and Curb Hunger

Smelling dark chocolate before and during workouts may help you perform more repetitions and reduce hunger after exercise, new research finds. Getty Images Smelling dark chocolate before and during a leg workout helped participants perform more repetitions. Though the exact mechanism remains unclear, researchers suspect that certain scents trigger physiological changes that may affect physical performance. Other scents, including peppermint and citrus, have also been shown to affect exercise. The smell of dark chocolate might help you get a few more reps on leg day at the gym. New research suggests that simply inhaling the aroma before and during a workout could help people improve exercise performance without taking a single bite of chocolate. In an exploratory study published in Frontiers in Physiology , researchers found that healthy young men completed significantly more repetitions during a leg-extension workout after smelling 90% dark chocolate than after smelling water, the experiment’s control. Participants exposed to the dark chocolate scent also reported feeling less hungry and fuller. A milk chocolate scent also improved performance, though to a lesser extent, and appeared to produce a different psychological response. The study adds to a growing body of research suggesting that odors may influence athletic performance through complex interactions between the brain, appetite, and perception. “Their findings, showing greater improvements in performance with dark chocolate, align well with other findings in the literature, where lower appetite and higher fullness are associated with better performance,” said Marie-Eve Mathieu , PhD, Canada Research Chair, physical activity and juvenile obesity, at Université de Montréal. Mathieu wasn’t involved in the research. Mathieu has published research on the effects of scents, including peppermint , ammonia, lavender, and citrus, on athletic performance. However, given the limitations of the experiment, experts stress that the new study should be viewed as an intriguing first step, not definitive proof. The study was relatively small, involved only young resistance-trained men, and evaluated performance during a single type of exercise performed after an overnight fast. “We need to be cautious about drawing broad conclusions,” said Kristin Kirkpatrick , president of KAK Consulting and a dietitian at the Cleveland Clinic Department of Wellness & Preventive Medicine in Ohio. Smelling dark chocolate led to more reps To explore whether chocolate odors could influence exercise performance, researchers recruited 23 healthy men who regularly participated in resistance training. Each participant completed three laboratory sessions, one with each of three different odors: 90% dark chocolate, 60% milk chocolate, and a water-based control. The sessions were separated by at least four days, and all testing took place after an overnight fast lasting at least 10 hours. Before exercising, participants smelled one of the prepared odor samples for 30 seconds at several time points while rating their hunger, fullness, desire to eat, and how pleasant they found the scent. They then performed repeated sets of leg extensions until they could no longer continue. Before each new set, they again smelled the assigned odor. The results showed clear differences between the three scents. Participants exposed to the 90% dark chocolate odor completed an average of 18 more repetitions than they did during the control condition. The scent of milk chocolate resulted in nine more repetitions than the control group. Researchers also found that participants completed about one additional exercise set after smelling dark chocolate compared with either milk chocolate or the control. Researchers also found that the scents had distinct effects on feelings related to satiety and perceived exertion. Before exercise, the dark chocolate odor consistently reduced hunger, desire to eat, and prospective food consumption while increasing feelings of fullness compared with both milk chocolate and the control condition. Milk chocolate, on the other hand, did not produce the same appetite-suppressing effect. Instead, participants consistently rated its aroma as more pleasant than either dark chocolate or the control. “The fact that this study investigated appetite sensations and pleasantness as potential mechanisms is a strength. In this study, dark chocolate appears to work through a reduction in appetite and an increase in fullness, while milk chocolate appears to work through pleasantness,” Mathieu said. The exact mechanisms by which scent may improve performance remain unclear. The authors suggest it could be linked to the endocrine cephalic phase response , the body’s anticipatory physiological reaction to the sight, smell, or taste of food before it is actually consumed. The researchers say that scents, including chocolate, could trigger physiological changes that affect performance. The study ...

More: New research suggests that simply inhaling the aroma before and during a workout could help people improve exercise performance without taking a single bite of chocolate. The study adds to a growing body of research suggesting that odors may influence athletic performance through complex interactions between the brain, appetite, and perception.

TL;DR: Smelling dark chocolate before and during workouts may help you perform more repetitions and reduce hunger after exercise, new research finds.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Sciencedaily Jul 9, 03:04

Scientists found a surprising problem with sugar-free diets

A surprising new study suggests that completely eliminating sugar may backfire. Mice on a sucrose-free low-fat diet showed worse blood sugar control, increased inflammation, disrupted gut bacteria, and signs of fatty liver compared with mice that consumed some sucrose. Researchers say the results highlight the importance of a balanced diet and a healthy gut microbiome rather than focusing solely on cutting out sugar.

More: Scientists found a surprising problem with sugar-free diets. Mice on a sucrose-free low-fat diet showed worse blood sugar control, increased inflammation, disrupted gut bacteria, and signs of fatty liver compared with mice that consumed some sucrose.

TL;DR: A surprising new study suggests that completely eliminating sugar may backfire.

Read original at Sciencedaily →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Bbc Jul 8, 23:10

Disability benefit not fit for purpose, minister leading review says

Sir Stephen Timms says personal independence payments (Pip) in England and Wales need changing.

More: Disability benefit not fit for purpose, minister leading review says. Sir Stephen Timms says personal independence payments (Pip) in England and Wales need changing.

TL;DR: Sir Stephen Timms says personal independence payments (Pip) in England and Wales need changing.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 8, 20:12

No Link Between Prenatal Tylenol Use and Autism, ADHD, Multiple Studies Confirm

Research shows that there is no link between taking Tylenol during pregnancy and a higher risk of autism and ADHD. Image Credit: Getty Images In September 2025, the Trump administration suggested that taking Tylenol during pregnancy may raise the risk of autism in children. Many experts have spoken out against this statement. Multiple studies published in 2026 confirmed that there is no evidence to show a link between Tylenol during pregnancy and increased risks of autism or ADHD, including a new 20-year study from Hong Kong. A large Danish study also found no link between Tylenol and an increased risk of autism. A gold standard systematic review and meta-analysis found no evidence to support the idea that acetaminophen during pregnancy raises the risk of autism, attention deficit hyperactivity disorder (ADHD), or intellectual disabilities. A growing body of evidence, including several new, peer-reviewed studies in 2026, shows that there is no link between using Tylenol (acetaminophen) during pregnancy and an increased risk of autism, attention deficit hyperactivity disorder (ADHD), and intellectual disabilities. In September 2025, the Trump administration suggested that taking Tylenol during pregnancy may raise the risk of autism in children . Following the announcement, the Food and Drug Administration (FDA) initiated changes to the labels on Tylenol to include a mention of a possible association between the medication and the risk of autism and ADHD.  However, the exact cause of autism (autism spectrum disorder) is still not entirely understood, according to the National Institute of Environmental Health Sciences (NIEHS) .  Medical experts have also spoken out, emphasizing the fact that a causal relationship was never established between acetaminophen and neurocognitive outcomes such as autism. “Suggestions that acetaminophen use in pregnancy causes autism are not only highly concerning to clinicians but also irresponsible when considering the harmful and confusing message they send to pregnant patients, including those who may need to rely on this beneficial medicine during pregnancy,” said the American College of Obstetricians and Gynecologists (ACOG) president Steven J. Fleischman , MD, MBA, FACOG, in the organization’s 2025 statement . Multiple reviews and studies , have shown no link between the use of acetaminophen during pregnancy and autism or ADHD . This includes a gold-standard systematic review and meta-analysis published March found no evidence to suggest that acetaminophen use during pregnancy increases the risk of autism, ADHD, or intellectual disabilities . In this Healthline studies roundup, we highlight two additional, peer-reviewed studies published in 2026 with large samples and data sets that confirmed that there is no link between prenatal acetaminophen use and neurological conditions such as autism. Large, new study shows no association between Tylenol and autism, ADHD A 20-year study out of Hong Kong published in JAMA Internal Medicine on June 29, 2026, is the latest research to show that there is no causal link between Tylenol, also known as paracetamol, use in pregnancy and autism or ADHD. The study examined a cohort of 708,020 mother-child pairs, of whom approximately 43.3% had prenatal acetaminophen (paracetamol) exposure. The researchers then used sibling-matched analysis to check for autism and ADHD in the child participants. They found that prenatal exposure to acetaminophen was not associated with an increased risk for autism or ADHD. These findings were consistent across exposure timing, dosage, and pattern. “The exaggerated hype and misrepresentation about acetaminophen [Tylenol] increasing the risk of autism and ADHD during pregnancy has been exploited, harmful to pregnant women, and causing unnecessary confusion,” Ross told Healthine in a previous interview . Ross wasn’t involved in the study. “Tylenol is commonly used to treat fever, headache, and pain during pregnancy,” she said. This study adds to the growing evidence and expert opinion showing that the use of Tylenol during pregnancy is safe when you follow the instructions of your healthcare professional. Danish study verifies no link between autism and Tylenol A large Danish study published in April 2026 in JAMA Pediatrics also showed no link between the use of Tylenol during pregnancy and the risk for autism.  The study examined 1.5 million children born between 1997 and 2022. Among these, 31,098 were exposed to Tylenol in utero. The researchers found that 3% of the unexposed children were diagnosed with autism, while only 1.8% of the children who were exposed were given a diagnosis. This lack of association between Tylenol during pregnancy and autism persisted when the Danish researchers took into account individual risk factors, such as the trimester of pregnancy when exposure occurred and the dosage used. G. Thomas Ruiz , MD, an OB-GYN and the lead OB/GYN at MemorialCare Orange Coast Medical Cen...

More: A large Danish study also found no link between Tylenol and an increased risk of autism. They found that prenatal exposure to acetaminophen was not associated with an increased risk for autism or ADHD. Ross wasn’t involved in the study.

TL;DR: Research shows that there is no link between taking Tylenol during pregnancy and a higher risk of autism and ADHD.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Bbc Jul 8, 05:29

More or less protein? The foods to get you through a heatwave

Comments As temperatures exceed 30C (86F) in some parts of the UK this week, the last thing people want to do is turn on the oven.

More: Not only can cooking in hot weather feel like a chore, but many of us find ourselves feeling less hungry altogether. Even though they run for longer, they're typically more energy efficient and release even less heat than the air fryer. The reality, though, is that simply by eating and digesting protein, our bodies produce more heat than other food groups.

TL;DR: When turning on the oven is a no-no and you're bored of salads, these foods (and drinks) will help to beat the heat.

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jul 7, 22:22

Losing Just 78 Minutes of Sleep a Night Over 6 Weeks May Lead to Weight Gain

A new study found that adults who slept about 78 fewer minutes each night for six weeks gained nearly a pound and became more sedentary, highlighting the important role sleep plays in maintaining a healthy weight. A woman lying on a bed. A new study suggests not getting enough sleep each night may lead to weight gain. Those who lost an average of 78 minutes of sleep per night gained almost 1 pound over 6 weeks. People who were short on sleep were also found to be more sedentary. Sleep deprivation can cause weight gain by altering hunger hormones. Getting good quality sleep is an important part of a healthy weight-management strategy. We all know that not getting enough sleep can leave us feeling groggy and out of sorts, but did you know it might also be quietly adding pounds to your body?  A recent study conducted by researchers at Columbia University found that even a modest reduction in sleep — just an hour and a half less per night for six weeks — can cause noticeable weight gain and changes in the body.  According to the study’s authors, these findings, published on July 7, 2026, in the Annals of Internal Medicine , highlight the role of sleep in managing weight, especially for those already at risk of heart and metabolic diseases. How researchers examined the relationship between sleep and weight To understand the connection between sleep and body weight, the researchers combined data from two clinical trials involving 95 adults ages 20 and older.  These participants were all considered at elevated risk for heart and metabolic problems, but typically slept at least seven hours a night before the study began. The trials used a randomized crossover design, meaning each participant experienced two different sleep conditions over separate six-week periods.  In one condition, called “adequate sleep” (AS), participants maintained their usual sleep habits, averaging seven or more hours of rest each night.  In the other condition, known as “sleep restriction” (SR), participants were asked to delay their bedtime by 1.5 hours, cutting their sleep time by about 90 minutes every night. To ensure participants followed their sleep schedules, the researchers monitored their sleep using wrist-worn devices called “actigraphs,” which tracked movement and estimated sleep duration.  Participants also kept sleep diaries, and the research team regularly reviewed these to adjust schedules and ensure compliance. Throughout the study, participants underwent detailed measurements before and after each sleep condition. These included weighing participants, measuring waist circumference, and using magnetic resonance imaging (MRI) to assess body composition, including fat and muscle volumes.  The researchers also collected blood samples to measure hormones related to hunger and energy balance, such as leptin and ghrelin. In addition, the study tracked daily activity levels using the same wrist devices to see if changes in sleep affected physical activity or sedentary behavior.  For a smaller group of participants, total daily energy expenditure — the number of calories burned — was measured using a method called “doubly labeled water.” By comparing data collected after adequate sleep and after sleep restriction, the researchers aimed to uncover how a real-world pattern of mild but chronic sleep loss might affect body weight and related health factors. Sleep restriction was associated with weight gain When the researchers examined the data, they found that participants who slept about 78 minutes less per night during the sleep restriction phase gained an average of 0.45 kilograms (nearly 1 pound) compared to when they had adequate sleep. Waist circumference also increased by about half a centimeter during the sleep restriction period, indicating that some of the weight gain was concentrated around the abdomen, which is a known risk factor for heart disease. MRI scans showed an increase in whole-body volume, but the proportion of body fat versus muscle did not change, suggesting that weight gain was not solely due to fat accumulation. Looking at the hormones, leptin levels — which signal the body’s energy stores — increased with sleep restriction, consistent with the observed weight gain.  Ghrelin, often called the “hunger hormone,” tended to decrease slightly, though this change was not statistically significant.  There was no change in glucagon-like peptide-1 (GLP-1), another hormone involved in appetite regulation. Physical activity data revealed that participants spent about 17 more minutes per day being sedentary during the sleep restriction period compared to when they had adequate sleep. However, time spent in moderate-to-vigorous physical activity did not change, which could contribute to weight gain by reducing overall calorie expenditure. Among the smaller subset of participants who had their total daily energy expenditure measured, no significant difference was found between the two sleep conditions. This suggests that...

More: Losing Just 78 Minutes of Sleep a Night Over 6 Weeks May Lead to Weight Gain. People who were short on sleep were also found to be more sedentary. Waist circumference also increased by about half a centimeter during the sleep restriction period, indicating that some of the weight gain was concentrated around the abdomen, which is a known risk factor for heart disease.

TL;DR: A new study suggests not getting enough sleep each night may lead to weight gain.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jul 7, 20:23

Heart Attack Risk 31% Lower for People with Strong Chest, Back Muscles

Research shows that stronger, better quality back and chest muscles may reduce the risk of a heart attack. Image Credit: minamoto images/Stocksy A recent study found that people with strong back and chest muscles may have a lower risk of heart attack. Researchers used artificial intelligence (AI) to analyze heart scans of study participants. Muscle quality in these areas was also found to matter more than size for overall heart attack risk. People with stronger back and chest muscles may have a lower risk of heart attack, according to a new study that used artificial intelligence (AI) to analyze heart scans. The study, published in Radiology on June 30, suggests that people with g reater muscle density in their chest and back were less likely to have a heart attack and also less likely to die within a decade of a heart scan. “We think that [this] shows that the person has healthier muscles overall and is more likely to take part in exercise. This is evidence to support exercise being good for the heart,” Michelle Williams , PhD, Professor of Cardiovascular Imaging at the University of Edinburgh, and one of the study authors, told Healthline. This adds to a growing body of evidence showing that strength training, also known as resistance training, can improve cardiovascular health. In 2023, the American Heart Association (AHA) found that resistance training can not only help improve or maintain muscle mass but also reduce cardiovascular risk factors. The AHA also noted that strength training alone or in combination with aerobic exercise can improve both traditional and nontraditional cardiovascular disease risk factors. How AI helped show muscle quality in study participants Around 350,000 people in the UK have a coronary computed tomography angiography (CCTA) scan each year. This is to identify narrowing or blockages in the coronary arteries that supply blood to the heart, which can put a person at risk for a heart attack . The study used AI to analyze routine CCTA scans from 1,722 individuals, with an average age of 57, who were experiencing chest pain . The researchers used AI to examine the participants’ upper-body muscles, organs, bones, and fat. The analysis included muscle attenuation, which refers to the brightness or darkness of the muscles in the scan. The AI took no more than 1 minute to assess a person’s muscle quality from a single scan. It would take a radiologist several hours to do the same thing. A brighter image is associated with better muscle quality and density, indicating a lower fat proportion in muscle. Fat within the muscles has previously been associated with lower cardiovascular health. The study grouped participants together based on how their muscles appeared on the scans. The researchers then investigated the rates of heart attacks and early deaths using health records. Muscle strength and quality may reduce heart attack risk The researchers found that for every 10-point increase in a scan indicating better-quality muscle with less fat, a person had a 31% lower chance of having a heart attack. The individuals were also 39% less likely to die within 10 years of having the scan. “Having good quality muscles means that they are being used and exercised. So having toned muscles is good for your heart. Being muscly alone didn’t make a difference. Quality, not quantity, was important,” said Williams. These findings remained true even after taking into account other factors that can increase a person’s risk of a heart attack, including: age sex amount of calcium built up in the arteries “While the findings are compelling, they represent an association, not proof of cause and effect,” said Cheng-Han Chen , MD, board certified interventional cardiologist and medical director of the Structural Heart Program at MemorialCare Saddleback Medical Center in Laguna Hills, CA. Chen wasn’t involved in the study. “More research is needed to better understand the underlying mechanisms driving this relationship and how muscle health directly impacts cardiovascular outcomes.” How routine scans can make a difference in the future The results of the study suggest that, in the future, routine heart scans could be used to identify individuals with lower-quality upper-body muscle, who may be at greater risk of a heart attack. “In the future, it may be possible [to] use information from a routine CT scan to identify patients who might benefit from targeted interventions, including exercise, lifestyle, or medications. More research into this will be required first,” said Williams. Tips for strong and healthy muscles Keeping your muscles healthy is an important part of your overall health. Chen suggested that regular strength training and other load-bearing exercises can help maintain muscle quality, improve metabolic health, and support long-term well-being. “These activities don’t have to be extreme. Even moderate, consistent effort can make a meaningful difference,” he said. What...

More: Heart Attack Risk 31% Lower for People with Strong Chest, Back Muscles. Fat within the muscles has previously been associated with lower cardiovascular health. Chen wasn’t involved in the study.

TL;DR: Research shows that stronger, better quality back and chest muscles may reduce the risk of a heart attack.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jul 7, 18:33

5 Cups of Coffee Daily May Lower Your Liver Disease, Cancer Risk By 47%

Recent research has found that drinking coffee may help reduce your risk of liver disease and cancer. Image Credit: GNDphotography/Getty A recent study has shown that drinking coffee may help reduce your risk of liver disease and cancer. The researchers found that the more coffee you drink, the greater the potential protective effects. Using sugars or sweeteners in your coffee can slightly reduce the protective effects. It is still important to limit your intake of sugar, sweeteners, and highly processed coffee creamers. Your morning cup of coffee may be doing more than boosting your energy. New research suggests it might also help lower your risk of liver disease and liver cancer. The study, published July 1 in Clinical Gastroenterology and Hepatology , found that those protective effects increase with greater coffee consumption. Participants who drank five or more cups of coffee a day generally saw the greatest liver health benefits, including the largest reduction in liver cancer risk, though adding sugar or other sweeteners may slightly reduce those benefits. “The results from this study are not surprising since we have prior research suggesting coffee’s positive role in liver and cardiometabolic health,” said Michelle Routhenstein , preventive cardiology dietitian at Entirely Nourished. Routhenstein wasn’t involved in the study. However, the findings show an association rather than proving that coffee directly prevents liver disease and cancer. More coffee was linked to greater liver health benefits The study analyzed 354,957 participants ranging in age from 40 to 69 from the UK Biobank who had no baseline cirrhosis or hepatocellular carcinoma. Researchers tracked cases of cirrhosis, liver cancer, and liver-related deaths among participants. Cirrhosis is a condition in which the liver is permanently damaged or scarred. The scar tissue replaces healthy tissue, causing the liver to not function properly. An estimated 1 in 400 adults in the United States has cirrhosis. Hepatocellular carcinoma (HCC) is a primary tumor of the liver. It occurs in around 85% of people with cirrhosis. HCC is the fifth leading cause of cancer death worldwide. It is also the second leading cause of cancer death, after lung cancer, in males. The study found that the potential protective effect of coffee appeared to increase the more the participant drank: 1 to 2 cups daily was associated with: 20% lower risk of cirrhosis 24% lower risk of liver cancer 31% lower risk of liver-related death 3 to 4 cups daily was associated with: 35% lower risk of cirrhosis and liver cancer 41% lower risk of liver-related death 5 cups or more daily was associated with: 32% lower risk of cirrhosis 47% lower risk of liver cancer 42% lower risk of liver-related death “One of the most exciting aspects of this study is that we were able to connect epidemiologic observations with objective biological evidence,” Hyunseok Kim , MD, transplant hepatologist at Cedars-Sinai Medical Center in Los Angeles, CA, first author of the study, told Healthline. “We found consistent associations across clinical outcomes, MRI-based liver imaging, and proteomic biomarkers, which strengthens confidence that coffee is linked to healthier liver biology rather than simply healthier lifestyle habits,” he said. Routhenstein noted that an interesting finding in this study was that these liver benefits were observed in both decaf and caffeinated coffee, suggesting that polyphenols and antioxidants are likely playing a role, rather than caffeine alone. “Coffee contains antioxidants such as chlorogenic acid, caffeic acid , and ferulic acid , which help reduce oxidative stress and inflammation , which may help protect liver cells from damage while also supporting cardiometabolic health,” she said. The researchers’ next goal is to identify the specific compounds and biological pathways responsible for these associations and ultimately determine whether these findings can be translated into more personalized strategies for liver disease prevention. Tips for consuming coffee safely Kim told Healthline that it’s important to remember that coffee should complement, not replace, other healthy habits. Maintaining a healthy weight, exercising regularly, limiting excessive alcohol, and controlling diabetes and cholesterol remain the cornerstones of liver disease prevention. However, you can still enjoy your daily coffee and reap its benefits. Routhenstein said that she suggests sticking to 1 to 3 cups of coffee a day. “If you enjoy coffee black, that is the [best] way to reap the benefits. Try to limit added sugars, flavored syrups, whipped cream, and highly processed creamers, which can contribute to excess calories, blood sugar spikes, and inflammation, and negate [coffee’s] proactive liver and heart benefits,” she said. Routhenstein also recommends drinking caffeinated coffee earlier in the day so it doesn’t interfere with your sleep. “Sleep plays an important role in me...

More: 5 Cups of Coffee Daily May Lower Your Liver Disease, Cancer Risk By 47%. Image Credit: GNDphotography/Getty A recent study has shown that drinking coffee may help reduce your risk of liver disease and cancer. Routhenstein wasn’t involved in the study.

TL;DR: Recent research has found that drinking coffee may help reduce your risk of liver disease and cancer.

Read original at Healthline →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Bbc Jul 7, 09:00

Inside Health

Close menu Episode details Radio 4 , · 07 Jul 2026 , · 28 mins An experimental treatment to “reset” the immune systems of people with autoimmune disease is showing transformative results in early tri…

More: Close menu Episode details Radio 4 , · 07 Jul 2026 , · 28 mins An experimental treatment to “reset” the immune systems of people with autoimmune disease is showing transformative results in early trials. James visits the NIHR Clinical Research Facility in Manchester to meet Kathy.

TL;DR: Are mosquitos biting earlier and how to optimise sperm.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 6, 19:01

Generic Mounjaro, Zepbound May Be Coming, Rivaling Current GLP-1s

Federal regulators have agreed to review a Swiss pharmaceutical company’s applications for two cheaper generic versions of Zepbound and Mounjaro. MK Photo/Alamy Stock Photo Federal regulators have agreed to review the applications from Swiss pharmaceutical company Sandoz for two cheaper generic versions of the tirzepatide medications Zepbound and Mounjaro. Eli Lilly’s patents on those two brand-name drugs are valid in the United States until 2036, but they are expiring in other countries. Experts say a less expensive version of these GLP-1 medications would give more people access to these effective weight-loss drugs. Some less expensive versions of the GLP-1 medications Mounjaro and Zepbound are now officially in the government approval pipeline. The U.S. Food and Drug Administration (FDA) has  agreed to review  two applications from Swiss manufacturer Sandoz to develop generic versions of those brand-name medications, both of which contain the active ingredient  tirzepatide . The FDA hasn’t specified how long this process will take, but on its website, the agency  states  that it typically completes reviews of standard drug applications within 10 months. Sandoz has requested approval of their generic medications for the same uses as Mounjaro and Zepbound, which are manufactured by Eli Lilly. Mounjaro  is approved as a treatment for type 2 diabetes, while  Zepbound  is authorized as a treatment for obesity as well as sleep apnea. The Sandoz generic drugs would be taken as a weekly injection, just like Zepbound and Mounjaro. Both are intended to be prescribed along with a lifestyle plan that includes a healthy diet and regular exercise. The generic medications are expected to be less expensive than Mounjaro and Zepbound. Those brand-name drugs can cost more than $1,000 per month if they aren’t covered by insurance. Sandoz estimates its product will cost between $200 and $400 per month without insurance. Generic medications tend to be  cheaper  because the pharmaceutical companies that make them don’t have to fund the initial scientific research that the brand-name companies conducted. “Sandoz is building its GLP-1 development platform, and this submission reflects true in-house innovation,” said  Claire D’Abreu-Hayling , the president of Generics Development and the chief scientific officer at Sandoz, in a  press statement .  “It represents a key first step in our efforts to bring this medicine to market and underscores our ambition to increase competition and expand affordability in a critical area of healthcare need.” Eli Lilly has patent protection in the United States for Mounjaro and Zepbound until 2036. That means generic tirzepatide drugs cannot be sold in the U.S. until the patent expires unless a company gets special permission from the FDA or a court. There was an exception made to these restrictions in December 2022 when the FDA declared there was a shortage of GLP-1 medications and allowed  compounded versions  of these drugs to be sold by telehealth providers. However, the FDA ruled in December 2024 that the GLP-1 medication shortage had ended and compounded versions were no longer allowed to be sold. Generic GLP-1 medications could lower cost, improve access There is an intense race among pharmaceutical companies to enter the GLP-1 medication market, especially in countries outside the United States, where patents are expiring. In June, Canadian health officials approved a generic version of Novo Nordisk’s Wegovy medication to be used as a treatment for weight loss. Wegovy is a weekly injection that contains the active ingredient semaglutide . The new generic drug is Sevian, an injectable medication manufactured by Canada-based Apotex. Canadian officials said they are also reviewing applications for six other generic medications with the ingredient semaglutide. One of them is Sandoz’s generic version of Ozempic that would be prescribed as a treatment for type 2 diabetes . Experts said generic GLP-1 medications should help reduce prices and boost supply. “It could be significant. The biggest obstacle for the medications is the cost,” said Pouya Shafipour , MD, a family and obesity medicine physician at Providence Saint John’s Health Center in California. “It’s a breakthrough to have tirzepatide available that is safe,” he told Healthline. Mir Ali , MD, a bariatric surgeon and the medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California, added that insurance companies might be more likely to cover these less expensive brands. He said the generic drugs should also perform similarly to the brand-name medications. “For the most part, they should be just as effective,” he told Healthline. Ali noted that having a larger supply of GLP-1 medications on pharmacy shelves is beneficial to everyone. “These are very effective medications as a tool to lose weight,” he said. “Access is still an issue for these effective medications.” Clar...

More: Experts say a less expensive version of these GLP-1 medications would give more people access to these effective weight-loss drugs. In June, Canadian health officials approved a generic version of Novo Nordisk’s Wegovy medication to be used as a treatment for weight loss. Experts said generic GLP-1 medications should help reduce prices and boost supply.

TL;DR: “These are very effective medications as a tool to lose weight,” he said.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Bbc Jul 6, 18:58

The weight loss pill that you can now buy in the UK

To play this video you need to enable JavaScript in your browser. This video can not be played Close Here's what you need to know about the Wegovy weight loss pill.

More: To play this video you need to enable JavaScript in your browser. This video can not be played Close Here's what you need to know about the Wegovy weight loss pill. Share close panel Share page Copy link About sharing Related topics Health Follow Health

TL;DR: All the you need to know about the weight loss pill Wegovy being available in the UK.

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jul 6, 17:22

‘Explosive Diarrhea Parasite’ Spreading Across 17 States, CDC Warns. How to Reduce Your Risk.

The CDC has reported a spread of a parasitic infection that causes diarrhea across 17 states, with a large cluster in Michigan. Image Credit: Catherine McQueen/Getty The CDC is raising concerns about the spread of a parasite that can cause explosive diarrhea.  Cyclosporiasis is typically spread through contaminated food or water. The CDC reported 145 cases across 17 states between May 1 and June 16. The FDA is working with the CDC to identify the potential sources of the parasitic infection.  The Centers for Disease Control and Prevention (CDC) recently warned of an increase in cyclosporiasis, a parasitic infection that can cause watery, often explosive diarrhea, among other symptoms. Cyclosporiasis is caused by the microscopic parasite Cyclospora. Symptoms of cyclosporiasis typically begin within 7 days of exposure to the parasite. The CDC reported 145 cases of cyclosporiasis and 20 hospitalizations between May 1 and June 16. However, more recently, a large, sudden cluster of cases has emerged in Michigan. A spokesperson for the Michigan Department of Health and Human Services (DHHS) told Healthline that as of July 2, the state had identified 300 cases. Typically, Michigan identifies only about 50 cases of cyclosporiasis per year. “MDHHS is working with [the] local health department in southeast Michigan to investigate [the] large and growing outbreak of cyclosporiasis, a diarrheal illness, to identify a common exposure,” said the DHHS spokesperson. “The department is coordinating the multi-jurisdictional investigation, assisting in case interviews, and sharing information with the CDC and MDARD [Michigan Department of Agriculture & Rural Development]. At this time, the source or sources have not yet been identified.” The Food and Drug Administration (FDA) and the CDC are also currently working to identify the potential sources of the outbreak across 17 states. So far, the reported cases have not been linked to a single common source. Seventeen states have been affected by the spread of cyclosporiasis As of June 16, 17 states had been affected by the increased spread of cyclosporiasis. These included:  Alaska Colorado Connecticut Florida Georgia Illinois Louisiana Massachusetts New Jersey New York North Carolina Ohio Pennsylvania Tennessee Texas Virginia Wisconsin At the time of the report, New York had reported the highest number of cases. However, the CDC noted that the number was likely higher than what was reported. The organization also stated that the infection cases may not be limited to these 17 states with known cases. This information did not include the sudden surge in cases in Michigan that occurred at the end of June. Individuals who reported being unwell with the infection ranged from 5 to 86 years old, with an average age of 42. Approximately 61% of cases have been seen in females. Those who were diagnosed with cyclosporiasis became ill after eating food in the United States. They did not report any travel in the 14 days preceding the onset of symptoms.  While there have been reports of hospitalizations from the infection, as of the CDC report, there have been no reports of death. Symptoms and treatment for cyclosporiasis While the main symptom of the infection is watery and often explosive diarrhea , other symptoms may include : abdominal cramping nausea bloating headache loss of appetite “The illness, untreated, can last for weeks, often in an on-and-off pattern. The major hazard is dehydration , which can cause problems for patients at the extremes of age, those with chronic medical conditions, and persons who are immunocompromised,” William Schaffner , MD, professor of the Division of Infectious Diseases at Vanderbilt University, told Healthline. Treatment for cyclosporiasis typically includes a selection of antibiotics . How cyclosporiasis spreads and how to prevent it The parasite that causes cyclosporiasis generally spreads when you eat food that is already contaminated with feces. It takes 1 to 2 weeks outside of the body for Cyclospora to become infectious after passing in a bowel movement. Because of this, transmission from person to person is unlikely. It is not fully known how Cyclospora gets into food and water. The best way to prevent the infection is to avoid eating contaminated foods and drinking contaminated water. “In recent years, outbreaks have occurred in the U.S. as a result of eating contaminated fresh produce, especially during the summer months,” said the DHHS spokesperson. Practicing safe food handling can help avoid contamination. This includes: Washing your hands with soap and water before and after handling and preparing raw fruits and vegetables. Wash all fruits and vegetables under running water before cutting, cooking, or eating. Scrub firm fruits and vegetables, like melons and cucumbers, with a clean produce brush. Cut away any damaged or bruised areas before preparing and eating. Refrigerate cut, peeled, or cooked fruits and vegetabl...

More: However, the CDC noted that the number was likely higher than what was reported. Those who were diagnosed with cyclosporiasis became ill after eating food in the United States. The best way to prevent the infection is to avoid eating contaminated foods and drinking contaminated water.

TL;DR: A spokesperson for the Michigan Department of Health and Human Services (DHHS) told Healthline that as of July 2, the state had identified 300 cases.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Bbc Jul 6, 00:06

Wegovy weight loss pill now available in UK - here's what you need to know

The once-a-day Wegovy weight loss pill is now available to buy privately from High Street and online pharmacies in the UK - but is not yet on the NHS.

More: The once-a-day Wegovy weight loss pill is now available to buy privately from High Street and online pharmacies in the UK - but is not yet on the NHS. It contains the same ingredient - semaglutide - as the Wegovy weight loss injections but is still advised to be used alongside a healthy diet and increased physical activity.

TL;DR: The once-a-day pill, from the makers of the Wegovy weight-loss jab, can now be bought privately in UK pharmacies.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 5, 13:59

These 10 Medications May Raise Your Risk of Heat-Related Illness

Certain medications, like GLP-1s, antidepressants, and beta-blockers, can increase your risk for heat-related illnesses. Image Credit: Evgeniya Pavlova/Getty Images Certain types of medications can make people more prone to heat-related illness. These include antidepressants, GLP-1 medications, and beta-blockers. They can cause dehydration, reduced sweating, and problems regulating temperature. It’s important to keep cool and drink plenty of water during hot weather, and if you experience symptoms of heat-related illness, seek medical help right away. July is often the hottest month of the year, with heatwaves becoming increasingly more common. Last year was the third-warmest July on record, with July 2024 being the hottest month ever recorded . While the summer sun and warmer temperatures are often enjoyable, for those who take certain medications, the warmer months may contribute to serious health issues.  “[People] are all aware of the risks of overheating, dehydration , and sunburn. But [they] should all be more aware of how medications can cause intolerance to summer heat,” said David Cutler , MD, board certified family medicine physician at Providence Saint John’s Health Center in Santa Monica, CA. According to the Centers for Disease Control and Prevention (CDC) , medications can contribute to heat sensitivity in various ways, including: reduced sensations of thirst interference with thermoregulation impaired sweating reduced cardiac output electrolyte imbalance cognitive impairment Here are 10 common medications that can be affected by hotter weather, and some tips for staying safe.  Antidepressants Certain types of antidepressants, like selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs) , can increase heat sensitivity . Heat sensitivity, or heat intolerance , occurs when you’re unable to regulate your body temperature effectively. “The most obvious effects of heat intolerance are seen in those taking medications which decrease sweating,” said Cutler. Antidepressants may disrupt typical sweating patterns. This may lead to either hyperhidrosis (excessive sweating) or anhidrosis (reduced sweating) in warmer weather. A disruption in sweating patterns can make it difficult for your body to cool itself, leading to heightened sensitivity to heat. Research from 2022 noted that these types of antidepressants can raise your core body temperature to 106° F (41°C). This can increase your risk of heat exhaustion and heatstroke . It may be useful for you to make a heat safety plan with your healthcare professional and share it with your loved ones. Antipsychotics Antipsychotic medications can also affect how your body reacts to the heat. Like antidepressants, antipsychotics can interfere with your body’s thermoregulation. They can also alter your perception and compromise your ability to sense and respond to heat. Certain antipsychotic medications, like lithium, can lead to dehydration-induced drug toxicity. Signs of lithium toxicity Signs of lithium toxicity include: dizziness tremors unsteadiness lethargy slurred speech confusion To prevent drug toxicity in hot weather, it is important to drink plenty of water and other fluids to stay hydrated. If you believe you are experiencing signs of lithium toxicity, you should contact a healthcare professional right away. Beta-blockers Beta-blockers can make you more sensitive to heat. Since they help the heart beat more slowly and with less force, these medications are most often used to treat irregular heartbeat and high blood pressure, but they have a range of other applications, including the treatment of anxiety disorders. Some common examples include metoprolol and propranolol . Beta-blockers can impair thermoregulation and elevate core body temperature. The American Heart Association (AHA) notes that these medications can exaggerate your body’s reaction to heat. It is important that you continue to take medications as prescribed and speak with your healthcare professional about potential side effects during the hotter months. ACE inhibitors Angiotensin converting enzyme (ACE) inhibitors are medications that are primarily used to treat high blood pressure. These medications can affect your body’s temperature regulation, increasing your risk of heat-related illness. They can also suppress your natural thirst response. It is important to take proper precautions to stay cool and to drink plenty of fluids to prevent dehydration. Diuretics Cutler told Healthline that diuretics force fluid through the kidneys and out of the body to control high blood pressure and heart failure. These medications could cause dehydration, a potentially grave danger in hot weather. Diuretics help increase the amount of water and salt that you expel from your body through urine. This increased fluid loss, along with increased sweating during warmer weather, can lead to dehydration. This means it is important to drink more fluids dur...

More: These 10 Medications May Raise Your Risk of Heat-Related Illness. The American Heart Association (AHA) notes that these medications can exaggerate your body’s reaction to heat. Diuretics Cutler told Healthline that diuretics force fluid through the kidneys and out of the body to control high blood pressure and heart failure.

TL;DR: Certain medications, like GLP-1s, antidepressants, and beta-blockers, can increase your risk for heat-related illnesses.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 4, 08:23

Why Carrie Ann Inaba’s Autoimmune Disorder Went Undiagnosed for Years

Photo Courtesy of Carrie Ann Inaba Dancing with the Stars judge Carrie Ann Inaba is opening up about her journey living with Sjögren disease. Sjögren disease is an autoimmune disorder that affects the glands responsible for producing saliva and tears. Inaba lived with symptoms for years before receiving a diagnosis. Dancing with the Stars ( DWTS ) judge Carrie Ann Inaba began experiencing a variety of symptoms she couldn’t explain in her 20s. They included corneal damage to her eyes, dry mouth, fatigue, brain fog, and pain throughout her body. “It’s like my body was just not working,” Inaba told Healthline, “All the things I could do, I couldn’t do anymore. And I couldn’t understand what it was.” She began researching her symptoms and found they were commonly associated with the autoimmune condition Sjögren disease . However, when she brought up the condition to her ophthalmologist, they shrugged her off, something she said is common for people living with Sjögren disease. “Sjögren disease…is something that people do not talk about…a lot of people don’t know how to pronounce it, don’t know much about it,” she said. Eventually, after years of living with symptoms, Inaba received a referral to a rheumatologist who diagnosed her with Sjögren’s disease in 2013. “I was grateful…so weird to say, but at least now I knew what I was dealing with. I knew the direction that I needed to search for more answers,” Inaba said. Sjögren’s disease can be challenging to diagnose and may take several years from the onset of symptoms to receive a definitive diagnosis, said Nina Couette , DO, rheumatologist and assistant professor at The Ohio State University Wexner Medical Center and College of Medicine. The main reason for this is that the hallmark symptoms, including persistent dry eyes and dry mouth, are common and can result from many different causes, including menopause , medication side effects, fibromyalgia , and other autoimmune diseases such as rheumatoid arthritis or lupus . “Because these symptoms overlap with so many other conditions, identifying Sjogren disease often requires careful evaluation and specialized testing,” Couette told Healthline. Physical and mental impacts of living with Sjögren disease One of the most difficult realities of living with Sjögren disease for Inaba is how it impacts her ability to dance—her “first love.” In 2013, her symptoms became debilitating, and she also experienced a physical injury. Both caused her to stop dancing. “It broke my heart, honestly,” she said. “I was having widespread pain throughout my body, and the fatigue was so immense. I was having so many flare-ups because I wasn’t managing my health, because I didn’t understand the condition.” Living with these symptoms soon began taking a mental toll, too. “Something that people don’t often talk about with Sjögren disease is the depression that comes along with it, and anxiety,” Inaba said. “The uncertainty of ‘When is a flare-up going to happen?’ The uncertainty of, ‘Do I have energy to get through the day today?’ You go on a high alert when you live with this condition, and it’s so challenging.” The impact of the disease often extends far beyond what people can see, said Couette. “Sjogren’s is a complex systemic autoimmune disease that can affect multiple organs and body systems,” she said. “In addition to dryness, patients may experience profound fatigue, brain fog , joint and muscle pain, nerve-related symptoms, and involvement of organs such as the lungs, kidneys, or nervous system.” Learning to manage Sjögren disease symptoms takes time Over time, Inaba learned how to best care for her body and mind. “Energy management is my number one focus at all times,” she said. “I’m constantly monitoring for how my body is reacting to things, and I really listen to my body.” She believes learning to “listen” to her body is one of the unexpected gifts of living with the disease. “I have really learned to pay attention to my body,” she said. “When it tingles about something, that’s a message, and I listen to it. If I’m starting to feel uncomfortable, that means this situation is not right for me, and I need to step away from it.” Her daily wellness routine includes yoga and mindful movement, such as rotating her joints to keep synovial fluid moving through her body. She also leans on acupuncture , Reiki , bodywork, and red-light therapy , and she sleeps on a heating pad. “Self-care and lifestyle measures play an important role in managing Sjögren disease,” said Couette. “[Adopting] a healthy lifestyle can help patients feel their best.” She said staying well hydrated, prioritizing adequate sleep, engaging in regular physical activity, managing stress, and following a balanced, nutritious diet can all contribute to improved overall well-being and quality of life. Medications also help Inaba manage symptoms While there is currently no FDA-approved treatment specifically for Sjögren disease, Couette said many current therapies foc...

More: “It’s like my body was just not working,” Inaba told Healthline, “All the things I could do, I couldn’t do anymore. “Sjögren disease…is something that people do not talk about…a lot of people don’t know how to pronounce it, don’t know much about it,” she said. “It broke my heart, honestly,” she said.

TL;DR: Medications also help Inaba manage symptoms While there is currently no FDA-approved treatment specifically for Sjögren disease, Couette said many current therapies foc...

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Bbc Jul 3, 14:56

German row over plan for workers to need sick note on first day of illness

A doctors' group says it "borders on madness" that patients will have to obtain the note in person.

More: German row over plan for workers to need sick note on first day of illness. A doctors' group says it "borders on madness" that patients will have to obtain the note in person.

TL;DR: A doctors' group says it "borders on madness" that patients will have to obtain the note in person.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jul 3, 14:05

Twice-Monthly GLP-1 Shot Helps Manage Blood Sugar, Weight Loss in Trial

A new biweekly GLP-1 injection has been shown to significantly reduce blood sugar in a clinical trial. Image Credit: Hannes P Albert/picture alliance via Getty Images A new GLP-1 medication demonstrated efficacy in reducing blood sugar in people with type 2 diabetes in a phase 2b clinical trial.  Bofanglutide is a biweekly (once every 2 weeks) injection compared to once-weekly shots like Ozempic and Wegovy.  The new biweekly GLP-1 also led to weight loss and improvement in cardiometabolic risk factors.  GLP-1 drugs like Ozempic and Wegovy are groundbreaking treatments for type 2 diabetes and obesity. As other drug manufacturers join the GLP-1 race, Gan & Lee Pharmaceuticals in Beijing, China, is developing a novel biweekly GLP-1 for weight loss. In a phase 2b randomized clinical trial, bofanglutide demonstrated a strong efficacy in reducing blood sugar in people with type 2 diabetes.  If approved, a biweekly shot could offer an alternative to once-weekly GLP-1 injections for the needle-averse. The results of the trial were published in Annals of Internal Medicine on June 30.  Biweekly GLP-1 lowers blood sugar, aids weight loss Bofanglutide is a biweekly (once every 2 weeks) injection, unlike most other GLP-1 medications (i.e., Ozempic , Wegovy , or Mounjaro ), which are once-weekly shots. The phase 2b clinical trial of bofanglutide included 272 adults with type 2 diabetes, with an average age of 50.8, from 37 sites across China. The participants were divided into five treatment groups:  bofanglutide 12 mg (biweekly) bofanglutide 18 mg (biweekly) bofanglutide 24mg (biweekly) bofanglutide 24mg (once weekly) semaglutide 1mg (once weekly) The primary measurement the researchers focused on was HbA1c levels from the baseline to the 24-week follow-up. At the end of 24 weeks, all bofanglutide groups showed significant reductions in blood sugar levels. Participants taking bofanglutide experienced weight loss and improvements in various cardiometabolic risk factors. How does bofanglutide compare to semaglutide? In some cases, blood sugar reductions among those taking bofanglutide were slightly greater than those taking semaglutide.  However, the semaglutide group received a relatively low dose, highlighting the need for further study. “More real-world comparisons are needed to determine whether this would be more effective than semaglutide,” said Mir Ali , MD, medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA. Ali wasn’t involved in the study.  The trial’s findings also suggest that bofanglutide could help manage diabetes and obesity.  However, Clare Thompson , a general practitioner and lead of the weight management service at Cadogan Clinic in the United Kingdom, further noted the study’s limitations. Thompson wasn’t involved in the study.  “The study is limited by its relatively small size and by population data from a Chinese cohort, where the starting BMI may be much lower than in Western populations,” she told Healthline. “[It] does not show what happens to patients after stopping these medications or titrating down to a maintenance dose. Twenty-four weeks is quite a short observation period for drawing full and meaningful conclusions,” she said. Bofanglutide side effects similar to other GLP-1s All GLP-1 drugs — semaglutide, bofanglutide, or tirzepatide — may cause side effects . Around 40% of people using a GLP-1 medication experience nausea, vomiting, diarrhea, or constipation.  Gastrointestinal symptoms, such as nausea, are among the most common . The researchers who conducted the trial found that while these side effects may be more frequent with bofanglutide, they were generally mild.  Other side effects may include a reaction at the injection site. This may include swelling, pain or discomfort, discoloration, or a rash. If you take a GLP-1 and experience side effects that concern you, speak with your healthcare professional.

More: Twice-Monthly GLP-1 Shot Helps Manage Blood Sugar, Weight Loss in Trial. Participants taking bofanglutide experienced weight loss and improvements in various cardiometabolic risk factors. Bofanglutide side effects similar to other GLP-1s All GLP-1 drugs — semaglutide, bofanglutide, or tirzepatide — may cause side effects .

TL;DR: A new biweekly GLP-1 injection has been shown to significantly reduce blood sugar in a clinical trial.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jul 2, 22:24

Louisiana Man Becomes First In Region to Be Functionally Cured of Sickle Cell Disease

A Louisiana man has become the first in the Gulf South to be functionally cured of sickle cell disease using gene therapy. Image Credit: Marti Sans/Stocksy Daniel Cressy of Louisiana has become the first person in the Gulf South to be functionally cured of sickle cell disease. The milestone highlights the growing promise of gene-editing therapies for the blood disorder, which disproportionately affects Black people. Cost, insurance approval, and limited access remain barriers for many eligible patients. A Louisiana man has become the first person in the state to be declared functionally cured of sickle cell disease after receiving the gene-editing therapy Casgevy, Manning Family Children’s Hospital announced on June 22. For Daniel Cressy, 23, the milestone marks the end of a more than two-year treatment journey. It also highlights the growing promise of CRISPR-based gene-editing treatments for people living with the blood disorder. Sickle cell disease (sickle cell anemia) affects more than 100,000 people in the United States, with Louisiana having the highest per capita rate of any state. The inherited disorder causes red blood cells to become rigid and crescent-shaped, restricting blood flow and leading to painful vaso-occlusive crises, organ damage, stroke, infection, and other serious complications. It also disproportionately affects Black Americans. Casgevy is among the first CRISPR-based gene-editing therapies approved by the Food and Drug Administration (FDA) to treat sickle cell disease by targeting the underlying cause of the condition rather than simply managing its symptoms. Daniel Cressy’s journey to a functional cure Diagnosed with sickle cell disease as an infant, Cressy spent much of his childhood in and out of hospitals because of painful sickle cell crises. At times, he was hospitalized between six and 12 times each year. Although his symptoms became more manageable during high school, the disease continued to shape his future. Cressy had long dreamed of becoming a commercial airline pilot, but he later learned that the Federal Aviation Administration would not medically certify him due to his diagnosis. Hoping there might be another path forward, he appealed the decision. “The answer came back,” Cressy said in the statement released by Manning Family Children’s Hospital. “If I could cure my sickle cell disease either through a bone marrow transplant or through gene therapy, then I could become a pilot.” When Casgevy became available, Cressy decided to pursue treatment. The process ultimately took more than two years and included collecting his stem cells, chemotherapy to prepare his bone marrow, an infusion of the gene-edited cells, and months of recovery and follow-up care. On June 22, Cressy rang the ceremonial bell at Manning Family Children’s Hospital to celebrate the end of his treatment journey and being declared functionally cured. What it means to be functionally cured Doctors use the term “functionally cured” because treatments like Casgevy are designed to prevent sickle cell disease from causing the painful complications that have historically defined patients’ lives. Casgevy works by collecting a patient’s blood-forming stem cells and using CRISPR gene-editing technology to modify them so they produce higher levels of fetal hemoglobin. After patients undergo chemotherapy, the edited cells are returned to the body, where they can produce healthier red blood cells that are less likely to sickle and block blood flow. Although patients continue to receive long-term medical follow-up, many no longer experience the repeated vaso-occlusive crises that frequently require emergency care and hospitalization. In clinical trials supporting the therapy’s approval, most participants remained free of severe vaso-occlusive crises for at least 12 consecutive months after treatment. Why access to Casgevy remains limited Getting access to the treatment can also be challenging, and proved to be an obstacle that Cressy needed to overcome. “I wasn’t denied gene therapy … I just had to go through extra hoops because it was new and expensive,” Cressy told  People . “Trying to navigate approval took a lot out of me, but my friends who are flying jets and fighting sickle cell all kept me going. The team at Manning Family is amazing too.” Patients must undergo chemotherapy, receive care at specialized medical centers, and spend months recovering after treatment. Cost, insurance approval, and strict eligibility requirements continue to limit access for many people who could potentially benefit from the therapy. Cressy hopes his experience encourages others living with sickle cell disease to learn about emerging treatment options and advocate for the care they need. He has also founded the Privileged Pilots Project , a nonprofit dedicated to helping aspiring pilots facing health and life challenges, raising awareness about sickle cell disease, and expanding access to opportunities. “While many spend their...

More: The milestone highlights the growing promise of gene-editing therapies for the blood disorder, which disproportionately affects Black people. It also highlights the growing promise of CRISPR-based gene-editing treatments for people living with the blood disorder.

TL;DR: A Louisiana man has become the first in the Gulf South to be functionally cured of sickle cell disease using gene therapy.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 2, 18:51

Young Adults Are Aging Faster, Which May Be Driving Higher Cancer Rates

Young adults appear to be aging faster than the previous generation, which could explain the rising early onset cancer rates. ZeynepKaya/Getty Images Researchers say younger generations appear to be aging faster than previous generations. They say the phenomenon may explain why certain cancers are rising drastically in young adults. The reasons for faster biological aging aren’t clear, but unhealthy diets, sedentary lifestyles, and exposure to carcinogens are likely factors. Younger generations are aging biologically faster than previous generations, which may have dire health consequences. A new study published in  Nature Medicine on June 22 suggests that rapid cellular aging may explain why certain cancers have risen sharply in younger generations over the past decade. Researchers from Washington University School of Medicine in St. Louis say that cancer can develop when genetic damage has accumulated in cells. When DNA is damaged, it can transmit flawed instructions, leading to malfunctions in cell division. That disruption can lead to cancer. This type of damage is commonly seen as people age. Ketan Thanki , MD, a colorectal surgeon specializing in benign and malignant disease of the colon, rectum, and anus at the MemorialCare Todd Cancer Institute at Long Beach Medical Center in California, said the new research provides valuable information. “The study shows that using established markers of biological age , we have evidence that younger generations are aging faster than previous generations,” he told Healthline. “The study doesn’t pinpoint exactly why but points toward factors that research has been suggesting for years,” Thanki told Healthline. Why are young adults aging faster? The researchers cited a  2021 study that identified several factors contributing to faster biological aging. These included: obesity and metabolic dysfunction unhealthy diet prolonged sedentary time circadian disruption exposure to environmental chemicals However, the researchers noted that further studies are needed to determine why biological aging has accelerated in younger generations. “A better understanding of how generational differences in accelerated aging relate to early onset cancers is needed urgently,” the study authors wrote. “This question is central because early onset cancers show strong birth-cohort effects, with more recent generations experiencing higher risk as they age,” they continued. Younger generations have a higher ‘age gap’ To reach their findings, the researchers examined data on three generations of people listed in two data banks. They studied blood markers from more than 150,000 adults in the UK Biobank , comparing people born in the early 1950s with people born in the late 1960s and early 1970s. The researchers also examined health data from more than 10,000 adults in the United States’ All of Us  research program, which includes people born from 1965 onward. The researchers compared people born in the 1960s with those born during the 1990s. Their primary metric was  PhenoAge , a measure of biological aging based on chronological age and 9 blood biomarkers. The team used that metric to calculate an “age gap” score to estimate whether a person appears biologically older or younger than expected for their actual age. They found that younger generations appeared biologically older than the previous generations at the same chronological age. People born in the United Kingdom between 1965 and 1974 had a 23% higher standardized PhenoAge-defined age gap than those born between 1950 and 1954. Similarly, in the United States, people born during the 1990s had a 92% higher standardized age gap than those born between 1965 and 1969. Higher ‘age-gap’ linked to early onset cancer risk Using a subset of the data, the researchers examined whether the age-gap scores were associated with cancer risk. They discovered that people with higher age-gap scores were more likely to develop cancer before age 55. This was particularly true with cancers of the  lung ,  digestive system , and  uterus . The researchers added that every increase in age-gap score increased the risk of early onset solid cancers by 8%. The strongest association was for lung cancer, in which the risk rose by 57% They reported that the associations persisted even after controlling for factors such as: smoking obesity telomere length genetic predisposition Thanki said the trend is concerning. “Age-related morbidities — diseases that we have previously associated with the elderly — will become more and more common in younger people,” he said. “Beyond the burden on individual quality of life, this will lead to greater healthcare costs as a society and potentially even a shortening of life expectancy.” Thanki added that changes in how healthcare is approached need to be made. “We are already facing clinical and diagnostic challenges in younger adults, meaning unless we change how and how well we screen, we will miss more cases and see more patie...

More: Young Adults Are Aging Faster, Which May Be Driving Higher Cancer Rates. Younger generations are aging biologically faster than previous generations, which may have dire health consequences. “The study shows that using established markers of biological age , we have evidence that younger generations are aging faster than previous generations,” he told Healthline.

TL;DR: Higher ‘age-gap’ linked to early onset cancer risk Using a subset of the data, the researchers examined whether the age-gap scores were associated with cancer risk.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jul 2, 15:39

Sitting Too Much Raises Cancer Risk, But Short Bursts of Light Activity May Help

New research shows that prolonged periods of sitting or lying down could increase the risk of certain cancers. Image Credit: Justin Paget/Getty Images A new study found that prolonged sedentary behaviors can raise the risk of various cancers, including colorectal, pancreatic, and breast cancer.  Replacing just 1 hour of prolonged sedentary behavior per day with light physical activity reduced the risk of cancer death by 12%. While the findings don’t establish causality, they can help guide personalized strategies to break up sitting time.  Sedentary behaviors are ubiquitous in modern life. Many jobs require long periods of sitting, and many people enjoy streaming television shows and movies or playing video games. Whatever the reason, a sedentary lifestyle may raise the risk of various health issues.  A new study published in PLOS Medicine on July 2 found that prolonged sedentary behavior could increase the risk of many types of cancer.  However, the findings also indicate that breaking up your sitting time, even with just an hour of light activity, can greatly reduce the risk.  “A sedentary lifestyle can lead to a person becoming overweight,” said David Yashar , MD, hematologist-medical oncologist of MemorialCare Todd Cancer Institute at Long Beach Medical Center in Long Beach, CA. Yashar wasn’t involved in the study. “We know that an increased amount of fat causes inflammation, which is a known risk factor for cancer. Obesity has also been associated with the development of colorectal cancer,” Yashar told Healthline. Prolonged sitting raises cancer-related death risk by 10% The study analyzed data from 91,292 participants in the UK Biobank . Each participant had worn an activity monitor for 7 days and was followed for an average of 12.38 years afterward. During the study, activity was categorized in the following ways: prolonged sedentary (bouts of at least 30 minutes, with at least 90% of the time sedentary) interrupted sedentary (lasted less than 30 minutes or was broken up with more than 10% non-sedentary time) varying degrees of physical activity Yashar explained that sedentary lifestyles may lead to hormonal imbalances that may contribute to the development of certain hormone-sensitive cancers, such as breast cancer. Prolonged sedentary behavior was associated with a higher risk of cancer death and overall cancer incidence. It was associated with cancers, such as:  colorectal cancer breast cancer liver cancer kidney cancer pancreatic cancer ovarian cancer esophageal cancer thyroid cancer For each additional hour of uninterrupted prolonged sedentary behavior, there was a 10% higher risk of cancer-related death.  Light physical activity reduces cancer death risk by 12% Current guidelines recommend 150 minutes of moderate-intensity activity each week. However, this study shows that even light-intensity activity can lower your cancer risk. The researchers found that replacing at least 1 hour of daily prolonged sedentary behavior with light physical activity can reduce the risk of cancer death by 12%. “Our findings suggest that the health effects of sedentary behavior may depend not only on total sedentary time, but also on whether that time is accumulated in prolonged bouts or interrupted by activity,” the study authors said in a press release . “This pattern is biologically plausible: experimental studies have shown that interrupting prolonged sitting with short bouts of activity can improve metabolic responses compared with uninterrupted sitting.” According to the United Kingdom’s National Health Service (NHS) , light physical activity is anything that involves moving rather than sitting or lying down. Light physical activity may include: getting up to get a drink moving around your house walking at a slow pace cleaning and dusting vacuuming making your bed standing up Regular physical activity can benefit your health in many ways. Moderate-intensity activity may provide more benefits. However, it is important to remember that some movement is better than none. Breaking up your sedentary time with light activity can be a good stepping stone to more vigorous activity.

More: Sitting Too Much Raises Cancer Risk, But Short Bursts of Light Activity May Help. Obesity has also been associated with the development of colorectal cancer,” Yashar told Healthline. Prolonged sedentary behavior was associated with a higher risk of cancer death and overall cancer incidence.

TL;DR: However, this study shows that even light-intensity activity can lower your cancer risk.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jul 1, 18:14

Creatine Supplements May Help Treat Depression, Early Evidence Shows

A large review suggests that creatine could help treat major depressive disorder (MDD), but evidence is mixed. ATHVisions/Getty Images A large review suggests that creatine could be an adjunct treatment for major depressive disorder (MDD). However, not all studies in the review found the same benefits for treating depression symptoms with creatine. Those with depression who would like to try creatine should continue with existing treatments, using it only as an add-on. Experts note that creatine supplements have an excellent safety profile when taken as directed. Lifestyle choices such as good sleep, exercise, nutrition, and stress management can also protect brain health. Creatine monohydrate, a popular dietary supplement commonly used by athletes and fitness enthusiasts to build muscle, could serve as an adjunct treatment for depression. A large systematic review explored the potential benefits of creatine for mental health.  Researchers from the University of Ottawa and the University of Toronto analyzed randomized controlled trials (RCTs) conducted worldwide and found that creatine supplementation shows promise for improving symptoms of major depressive disorder (MDD) . Their findings, however, are mixed, highlighting the need for further large-scale studies. The results were published in Brain Medicine on June 30. Depression affects around 332 million people worldwide, according to the World Health Organization (WHO) . As the review authors highlight, many people experience only partial or no response to depression medications, making it essential to explore other treatment options. The authors say that creatine, known for its role in cellular energy metabolism, may help by providing an energy buffer for brain cells. This is particularly relevant, they add, because impaired energy metabolism and mitochondrial dysfunction have been linked to depression. Evidence for creatine as depression treatment The researchers examined the effects of creatine monohydrate supplementation on mental health conditions, focusing mainly on mood disorders.  The review included five RCTs with a total of 238 participants: 126 received creatine supplementation, and 112 received a placebo.  The average age was 36 years, and the majority of participants were female; two of the five trials enrolled only women. Supplementation doses varied between studies, ranging from 2 grams to 10 grams per day, with treatment durations typically lasting from 4 to 8 weeks. Some trials investigated creatine as an add-on to pharmacological treatments such as antidepressants , while others combined it with cognitive behavioral therapy (CBT) .  The researchers assessed depressive symptoms using standard clinical scales like the Hamilton Depression Rating Scale and the Patient Health Questionnaire. Due to variations in the studies, including differences in creatine dosage, length of treatment, and participant characteristics, the team summarized the findings in narrative form rather than performing a meta-analysis. They also noted that some clinical trial data were unavailable, limiting the overall assessment. Mixed evidence on creatine and depression The review found mixed evidence that creatine can help treat depression when used alongside standard care. Two papers based on the same clinical trial found promising results in women with major depressive disorder who took 5 grams of creatine daily in addition to the antidepressant escitalopram (Lexapro) . After eight weeks, those taking creatine had greater improvements in depression symptoms and were more likely to go into remission than those taking a placebo. Another study found that people receiving creatine alongside CBT experienced greater symptom improvement than those who received CBT with a placebo. On the other hand, other studies found little or no benefit. One trial involving people whose depression had not improved with antidepressants found that adding creatine did not reduce symptoms after four weeks. Another study in teenage girls with depression found no meaningful differences between several creatine doses and a placebo after eight weeks. A third study involving people with bipolar disorder also found no benefit, and two participants taking creatine developed hypomania or mania , suggesting it should be used cautiously in people with bipolar disorder. Across the studies, creatine was generally well tolerated, with only mild digestive side effects reported. However, most participants were female, and the studies were relatively small, making it difficult to know whether the findings apply to the broader population. The authors further noted that animal research suggests creatine may affect males and females differently, which could help explain why study results have varied. They say there are several reasons creatine could help relieve depression. It helps the brain produce and replenish energy needed for normal cell function and may also affect brain chemicals involved in regul...

More: Creatine Supplements May Help Treat Depression, Early Evidence Shows. However, not all studies in the review found the same benefits for treating depression symptoms with creatine. Depression affects around 332 million people worldwide, according to the World Health Organization (WHO) .

TL;DR: Lifestyle choices such as good sleep, exercise, nutrition, and stress management can also protect brain health.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jul 1, 15:54

Chronic Pain? Melatonin May Provide Some Relief, Study Finds

Melatonin alleviated chronic pain about as effectively as over-the-counter painkillers, a new study found. Grace Cary/Getty Images A new study found melatonin eased chronic musculoskeletal pain about as effectively as over-the-counter painkillers. The benefit was clearest for chronic pain, but results for post-surgical pain were less clear, the study found. The study reported that melatonin is safe in the short term at low doses, defined as less than 3 months and less than 5 milligrams. Experts advise talking with a doctor before trying melatonin for pain, particularly if you don’t currently have trouble sleeping or take other medications. Poor sleep and pain often reinforce each other. Pain can make sleep harder to come by, and lost sleep can make pain feel more intense. Research has linked lost sleep to increased inflammation and a weakened pain-control system. That relationship is one reason researchers have begun studying whether melatonin, a hormone that regulates the sleep-wake cycle, might also help manage pain. A study published June 30 in the journal PAIN found that melatonin supplements reduced chronic musculoskeletal pain with effects comparable to over-the-counter pain medications like ibuprofen and aspirin. The research examined both chronic pain — pain lasting three months or longer — and acute, short-term pain following surgeries for conditions like knee and hip replacements , spinal procedures, and fractures. Here’s what they found. How melatonin helps ease chronic pain The researchers say that melatonin’s effects may depend on the type of pain. For chronic pain , the reduction was large enough to rival common painkillers. For post-surgical pain, the results were less clear. Lead study author Kangchao Wu, a PhD candidate, physiotherapy researcher, and faculty member at the University of Sydney’s School of Health Sciences , explained the two ways melatonin can help reduce pain. The first is in the makeup of the hormone itself.  “Melatonin may have some intrinsic pain-relieving properties, such as antioxidant and anti-inflammatory effects, which are very crucial effects during the pain process,” Wu told Healthline. The other is more indirect. “Melatonin can improve people’s sleep, help them feel better, help them move better, reduce anxiety and depression related to pain, and help them stay active during the daytime,” Wu said. “All of that together can help reduce pain intensity.” The difference, Wu said, comes down to the root causes of each pain type. “Post-operative pain is more acute. Chronic musculoskeletal pain is often related to long-term conditions, like poor sleep, inflammation, and nervous system sensitivity. That’s maybe why we see a difference in melatonin’s effects between the chronic and post-operative groups,” he said. Even so, researchers frame melatonin as an add-on option, not a replacement for existing pain treatment. “Melatonin could be an adjunctive treatment to your existing pain treatments for chronic musculoskeletal pain, especially if you have co-existing sleep problems,” Wu said. What’s still missing, he noted, is an optimal dose and a clear read on long-term use. Who should and shouldn’t try melatonin for pain Wu advised those considering melatonin for pain to begin by discussing any sleep troubles with their doctor. “Melatonin is very well established for short-term treatment of insomnia. Based on current evidence, melatonin is proven to be safe if used short-term and at a low dose,” he said. Melatonin dosage and duration Wu said that, based on the study’s findings, short-term use was defined as less than 3 months, and a low dose was defined as less than 5 milligrams, noting that most of the trials included in the study used 3 milligrams. For people experiencing pain but don’t have trouble sleeping , he recommended a conversation with their doctor before starting melatonin. Melatonin side effects Melatonin is generally considered safe, but it may have side effects . Wu’s study analyzed side effects in patients who used the supplements for pain.  ”The most common side effects with melatonin were headache , nausea, and daytime drowsiness ,” Wu said. “But the side effect rate of melatonin was similar to the placebo group.” Meaning, people who took melatonin reported side effects at rates similar to those who took a placebo. Who should avoid melatonin Wu’s guidance above is specific to using melatonin for pain. Melatonin carries broader restrictions that apply regardless of why someone takes it. Those who are pregnant or nursing should not use melatonin, according to the National Institutes of Health (NIH) . People with certain health conditions — including rheumatoid arthritis and conditions that affect the kidneys or liver — shouldn’t take it without clearing it with a healthcare professional first.  Because melatonin can interact with other drugs and supplements, anyone taking over-the-counter or prescription medication should talk to their doctor before adding...

More: The benefit was clearest for chronic pain, but results for post-surgical pain were less clear, the study found. “Melatonin can improve people’s sleep, help them feel better, help them move better, reduce anxiety and depression related to pain, and help them stay active during the daytime,” Wu said.

TL;DR: Melatonin alleviated chronic pain about as effectively as over-the-counter painkillers, a new study found.

Read original at Healthline →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Sciencedaily Jul 1, 03:08

The supplements older adults actually need and the ones they don't

Supplements are often marketed as shortcuts to better health, but for many older adults, the real issue is whether they have a specific deficiency. Vitamins like B12 and D can play an important role when levels are low, while protein may be one of the most overlooked nutrients for maintaining strength and independence. More isn’t always better, though—some supplements can cause harm or interact with medications.

More: The supplements older adults actually need and the ones they don't. Vitamins like B12 and D can play an important role when levels are low, while protein may be one of the most overlooked nutrients for maintaining strength and independence. More isn’t always better, though—some supplements can cause harm or interact with medications.

TL;DR: Supplements are often marketed as shortcuts to better health, but for many older adults, the real issue is whether they have a specific deficiency.

Read original at Sciencedaily →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 30, 18:28

Statins Rarely Cause Severe Muscle Problems, Researchers Say

A large new study found that people taking statins are unlikely to develop serious muscle problems. Sol de Zuasnabar Brebbia/Getty Images New research reports that serious muscular disorders are rare for people who take statins to help lower cholesterol levels. Researchers say their findings are important because many people avoid taking statins out of fear of side effects like muscle aches. Experts say statins are an effective tool in lowering the risks of heart disease and stroke. The risk of serious muscle issues for people who take statins is extremely low, according to a large study. Researchers said less than 1% of people who took the commonly prescribed cholesterol-lowering medication in a study had a 10-year risk of statin-related serious muscular disorders higher than 10%. The results of the study were published on June 25 in  The Lancet Digital Health . The findings follow a  February study  that concluded that the risks of serious side effects from statins are low . Studies dispelling concerns over statin use are noteworthy considering that statins can help lower cholesterol levels by as much as 60% , and consequently reduce the risk of heart disease. Despite this,  past research  shows that less than half of the 50 million people in the United States who might benefit from statins actually take them. In addition, it’s estimated that as many as one-third of people prescribed statins  never fill  that prescription. The authors of the new study say that “widespread and often misattributed concerns” about statin side effects have led to “low statin uptake and poor adherence in individuals eligible for treatment, consequently leading to increased [cardiovascular disease] and related deaths.” “Clinical treatment decision making can be better informed by personalized risk information about treatment outcomes, including both benefits and harms,” the authors wrote. Yu-Ming Ni , MD, a cardiologist and lipidologist at MemorialCare Heart and Vascular Institute at Orange Coast Medical Center in California, said the new research delivers an important message. “When you look broadly across all people currently on statins, the rate of side effects is very low,” he told Healthline. “When you consider the value that taking a statin daily provides to prevent heart disease , it is rare that the risk from the medication side effects outweighs the benefit of taking it.” Serious effects on muscles rare with statin use To reach their findings, researchers in the new report looked at the electronic health record data of more than 1.7 million participants in the Clinical Practice Research Datalink . The data included males ages 50 or older and females ages 60 or older. The participants were from England and were registered with the database between 1998 and 2018. The researchers used a model that was developed to predict the 1-year, 5-year, and 10-year risks of serious muscle disorders associated with hospitalization or death, adjusting for competing mortality risk. The researchers reported that they discovered that about 0.04% of the people studied had a 10-year risk of statin-related serious muscle disorders above 10%. The researchers said they hope their findings will convince patients and medical personnel that the benefits from statin use far outweigh the risks. “Serious muscle disorders have… been perceived by patients and physicians as a major concern for statin use, despite the incidence in the population being very low,” the study authors wrote. “This study aimed to derive and validate a prediction model for the personalized risk of serious muscle disorders in individuals eligible for statin treatment, to better inform clinical decision making on statin treatment and improve the use of statins in [cardiovascular disease] prevention,” they added. Cheng-Han Chen , MD, an interventional cardiologist and medical director of the Structural Heart Program at MemorialCare Saddleback Medical Center in California, said the new research reaffirms the benefits of statins. “These results confirm our understanding that statins are a very safe and effective medication for treatment of heart disease,” he told Healthline. Roger Blumenthal , MD, Chair of the American Heart Association (AHA) 2026  Dyslipidemia Guideline  writing committee, agreed. “The incidence of muscle side effects with statin therapy is extremely low. The benefits of lowering LDL-cholesterol are clear,” he told Healthline. “This study will help inform patients and clear up misinformation on the web,” said Blumenthal, who is also director of the Johns Hopkins Ciccarone Center for the Prevention of Heart Disease and a professor of cardiology at Johns Hopkins Hospital in Baltimore. Mild statin side effects may cause issues for some Rita Redberg , MD, a cardiologist and a professor at the University of California San Francisco’s Department of Medicine, said that this latest research only examined muscle disorders that can lead to hospitalization or death. She ...

More: Experts say statins are an effective tool in lowering the risks of heart disease and stroke. The results of the study were published on June 25 in  The Lancet Digital Health . “These results confirm our understanding that statins are a very safe and effective medication for treatment of heart disease,” he told Healthline.

TL;DR: A large new study found that people taking statins are unlikely to develop serious muscle problems.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govWHO NutritionWikipedia

Healthline Jun 30, 17:10

Heart Failure Gets a New Definition, Experts Say It Will Transform Care

A new definition for heart failure emphasizes earlier detection to improve treatment outcomes and survival rates. Halfpoint Images/Getty Images Global health experts have updated the definition and guidelines for heart failure. The experts say the new guidelines were spurred by the rising prevalence of heart failure. The guidelines include a standard definition of heart failure, emphasize early detection, and discuss how heart failure can be effectively managed through appropriate interventions. Health experts in the United States and around the world have updated their guidelines for identifying and classifying heart failure. They say their goal is to improve the prevention, diagnosis, and management of heart failure. The update was sparked by the increase in heart failure prevalence, a condition now affecting more than  64 million adults  worldwide. The increase is driven in part by aging populations and the rising rates of conditions that contribute to cardiovascular disease, such as  obesity ,  type 2 diabetes , and  high blood pressure . The experts say the new document “details a consistent and comprehensive framework, emphasizing early detection and individualized risk reduction of heart failure.” In June, the “Second Universal Definition of Heart Failure” was published in the American Heart Association (AHA) journal  Circulation on June 18. The new definition was also published in the American College of Cardiology (ACC) journal  JACC , the  European Heart Journal , and the World Heart Federation’s journal  Global Heart on June 29. The new guidelines reaffirm and update the First Universal Definition of Heart Failure , issued in April 2021. The updated document will serve as the foundation for the upcoming AHA/ACC Heart Failure Guideline, which is expected to be published in late 2027. “Heart failure remains a major challenge that continues to grow globally, and inconsistencies in how it is defined have limited progress in research and treatment,” Mary Norine Walsh , MD, co-chair of the consensus document for AHA and ACC, and medical director of the heart failure program at Ascension St. Vincent Heart Center and Ascension St. Vincent Cardiovascular Research Institute in Indianapolis, said in a  press release . “This updated definition provides a clearer, more consistent framework to help clinicians identify risk earlier and guide more personalized treatment approaches that can help improve patient outcomes worldwide,” Walsh continued. New heart failure definition will guide targeted care The new guideline introduces a standard classification system for the causes of heart failure. The document authors say the new classification framework will help with standardized reporting of data from trials and registries. They add it will also allow clinicians to “better identify underlying conditions and guide targeted care beyond the current standard treatment for heart failure.” Gregg Fonarow , MD, interim chief of the Division of Cardiology at the University of California Los Angeles, director of the Ahmanson-UCLA Cardiomyopathy Center, and co-director of UCLA’s Preventative Cardiology Program, explained why a consistent definition is important. “The updated universal definition of heart failure matters because it finally brings global consistency to how we diagnose and describe heart failure,” Fonarow told Healthline. “By modernizing the definition, clinicians can improve early detection, tailor treatment more precisely, and ultimately improve outcomes for millions of people worldwide at risk and with heart failure,” said Fonarow, who helped write the first set of guidelines in 2021, but was not involved in the updated document. Kevin Shah , MD, a cardiologist and the program director of Heart Failure Outreach at MemorialCare Heart & Vascular Institute at Long Beach Medical Center in California, agreed. “These guidelines are important because they provide a common framework for how we define, identify, and classify heart failure,” he told Healthline. “The new definition helps align clinicians, researchers, health systems, and policymakers around the same language and approach to this condition.” Early detection of heart failure improves outcomes The new guidelines emphasize identifying people at risk or in the early stages of heart failure before symptoms are detected. The document authors say this emphasis will “support prevention and earlier intervention that reduces the risk of progression to advanced heart failure.” Fonarow listed several reasons why early detection is important. Among them: Heart failure is often preventable. Treatments for hypertension , diabetes , obesity, and  chronic kidney disease  can dramatically reduce risk. Once symptoms develop, the condition becomes harder to reverse. “The earlier we identify risk, the more effectively we can intervene and prevent onset or progression,” Fonarow said. “By the time many patients develop symptoms, heart damage may be well established,” add...

More: The increase is driven in part by aging populations and the rising rates of conditions that contribute to cardiovascular disease, such as  obesity ,  type 2 diabetes , and  high blood pressure . Treatments for hypertension , diabetes , obesity, and  chronic kidney disease  can dramatically reduce risk.

TL;DR: Halfpoint Images/Getty Images Global health experts have updated the definition and guidelines for heart failure.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jun 29, 19:47

EMT Simone Kelly On the Opioid Overdose That Went Viral: ‘Don't Be a Bystander’

Simone Kelly went viral after reviving a man with Narcan at the Knicks parade. Here, she shares her passion for treating addiction. Kelly, 24, a pre-med student and volunteer EMT, is pursuing a calling in emergency psychiatry and addiction. Courtesy of Simone Kelly Simone Kelly was off-duty during the New York Knicks celebration parade in Lower Manhattan when she climbed a subway platform at the World Trade Center to save a man’s life with Narcan on June 18.  Kelly, a 24-year-old volunteer EMT with the South Orange Rescue Squad in New Jersey, and a pre-med student at Drew University, captured the attention and hearts of millions. Her act of heroism demonstrated that anyone can step in during an opioid emergency . Kelly was joined by another anonymous healthcare worker and several others. “It was a bit chaotic — people in the crowd were just throwing things they thought might help,” Kelly told Healthline. “A bottle of water came up, and we poured that on him, hoping he’s just overheating from hyperthermia . Then someone tossed up Narcan , and I was glad there was someone else in the crowd who was gauging what this could be. At that point, there is no harm in administering Narcan, so that is what we did,” she said. Kelly said she normally carries intranasal naloxone with her everywhere, but that day, she left it at home to lighten her load at the parade. “It’s on my keys. It’s very bulky, and my keys have broken numerous times, not necessarily from the Narcan. But that day I did not have it,” Kelly said. “I remember standing in my kitchen with my keys in one hand and the Narcan in the other, like I don’t have pockets, I can’t bring a bag. I’ve always brought it, but never had to use it on the street.” Kelly’s passion for treating those with addiction is evident. She’s studying neuroscience with a minor in psychology and chemistry, and says she’s found some of her favorite people riding the ambulance as an EMT. Her calling, she says, is in emergency psychiatry and addiction. “On the ambulance, I find a certain type of compassion and empathy toward those patients that — from my experience out in the world — not everyone has, so it is my belief that if you have the patience and the bandwidth to work with people who need help in that way, you should 100% go into it,” Kelly said. “So I’ve really been dedicating a lot of my time to uplifting those communities and empowering those voices.” And Kelly wasted no time in doing just that. As an advocate for OnPoint NYC , an organization that provides people who use drugs with clean syringes, overdose prevention, and nonjudgmental health services, she’s helped raise nearly $8,000 . Healthline spoke with Kelly to learn more about what happened during the viral moment and how it inspired her to speak out about addiction. This interview has been lightly edited for clarity and length. What were the signs of an overdose that prompted you to act? Kelly: Unresponsiveness, like if someone is passed out and not responding, there are a few different directions it can go. If you want to tell if it’s an opiate overdose, you’re going to look at their eyes and their pupils. If they’re very constricted and small, that’s usually a telltale sign of opiate overdoses. I’m not saying there aren’t other reasons someone might have constricted pupils . But when you have someone unresponsive with pinpoint pupils, and on top of that, you see shallow, slow breathing — that’s what I saw up there, that’s what prompted me to use the Narcan. Were you surprised that the rescue went viral? Kelly: I think there was an inkling in the back of my mind when we were up there, and there were so many phones recording us that I had a feeling that I might come across this again. I had no idea the magnitude, nor the opportunities and doors that have opened to continue this conversation and empower others to take action. It has turned into a platform where I can discuss harm reduction and get in touch with those who feel strongly about it, and meet with organizations and coalitions working on the front lines. There have been numerous people who have reached out to say thank you for what you’ve done, like one person who said, “It touched me greatly because no one was there for my brother last year when it happened to him.” Kelly has been a volunteer EMT with the South Orange Rescue Squad for the past three years. Courtesy of Simone Kelly What doors has the rescue opened for you? Kelly: Our New Jersey Congresswoman, Analilia Mejia (D) spoke about this event during a congressional hearing and she mentioned my name. I was also just in the New York City Health Commissioner’s office [ Alistar F. Martin , MD], and I was able to have a conversation with him about the events that transpired, and I picked his brain about everything that happened on top of that platform, like, “Hey, what would you have done? This is what I saw, what if it was this? What if I was wrong?” Every time you do any sort of medicine, the...

More: She’s studying neuroscience with a minor in psychology and chemistry, and says she’s found some of her favorite people riding the ambulance as an EMT. As an advocate for OnPoint NYC , an organization that provides people who use drugs with clean syringes, overdose prevention, and nonjudgmental health services, she’s helped raise nearly $8,000 .

TL;DR: “It was a bit chaotic — people in the crowd were just throwing things they thought might help,” Kelly told Healthline.

Read original at Healthline →

Further reading: PubMed NutritionEatRightNutrition.govWikipedia

Healthline Jun 29, 15:12

FDA Clears AI Tool to Spot Cardiovascular Disease Risk Ahead of Symptoms

A first-of-its-kind AI tool was cleared by the FDA to detect underlying structural heart disease before symptoms present. ljubaphoto/Getty Images The FDA cleared the first artificial intelligence tool to detect hidden structural heart disease during routine ECGs. EchoNext is a heart screening designed to detect underlying disease before symptoms present. The new tool is credited with spotting severe, undiagnosed heart failure in a 45-year-old man who ultimately received a successful heart transplant. Cardiovascular disease, the leading cause of death globally, has not yet had an early-detection test — until now. On June 22, the Food and Drug Administration (FDA) cleared a new tool to detect heart disease early. EchoNext is an artificial intelligence tool that reads a standard electrocardiogram (ECG) and flags those at high risk for structural heart disease, according to its maker, Pathway Labs . The company said that it’s the first AI tool approved by the FDA to detect this kind of hidden heart disease from an electrocardiogram, and that the clearance covers six indications. In June, Nature Medicine published the first peer-reviewed case in which EchoNext flagged severe, undiagnosed heart failure in a 45-year-old patient who ultimately received a heart transplant. Larger trials are underway, and Pathway Labs has raised $8.5 million to expand into more health systems, according to the company. EchoNext was built by researchers at NewYork-Presbyterian and Columbia University, led by Pathway Labs’ founder and CEO Pierre Elias , MD, an assistant professor of Medicine in the Department of Biomedical Informatics at Columbia University Data Science Institute. “We don’t have a screening test for the most common cause of death in the world, which is most forms of cardiovascular disease,” Elias said in a video released by NewYork-Presbyterian. “So we asked ourselves, could we take a cheap and ubiquitous test, and using AI, turn it into a screening test? And it turns out, we can do exactly that,” Elias continued. How the AI tool detects structural heart disease Structural heart disease means there’s a problem with the heart’s valves, chambers, or walls, and it keeps the heart from working the way it should. Unlike a heart attack , which happens when a blocked artery cuts off blood flow, structural problems are mechanical and don’t always involve blockages. A valve can stiffen and fail to open fully, forcing the heart to work harder to pump blood through. A valve can leak, allowing blood to flow backward instead of forward. Or the heart muscle can grow too thick or too weak to pump efficiently. The electrocardiogram (ECG or EKG) is one of the most common tests for cardiovascular disease because it’s quick, noninvasive, and commonly available in doctors’ offices and other clinical settings. “The heart is a house, and the [ECG] tells us about the electricity. Sometimes, if the electricity demonstrates that there may be issues, we may need additional tests,” said Rachel Bond , MD, co-chair of the Women and Children Committee for the Association of Black Cardiologists. ECGs have long been used to detect irregular rhythms and heart attacks, not structural problems, which require an echo to diagnose. EchoNext is designed to bridge that gap. According to Pathway Labs, the tool analyzes the ECG waveform to flag those who should proceed to an echocardiogram. The company said the model was trained on more than 700,000 paired ECG and echocardiogram records across the NewYork-Presbyterian health system. In a 2025 study published in Nature , EchoNext correctly identified 77% of structural heart problems from ECGs alone, while cardiologists reading the same ECGs were accurate 64% of the time. EchoNext is cleared to flag six conditions. Pathway Labs has shared five of them: right-sided heart failure left-sided heart failure valve disease severe thickening of the heart muscle pulmonary hypertension These conditions often build quietly. According to the Nature study, symptoms of the most common forms, like heart failure and valve disease , can stem from many causes and often surface only late in the disease’s course, after the options for treating it have narrowed. AI screening could improve early detection EchoNext could catch disease earlier; Elias said it spots conditions “the human eye can’t.” It could also help rule out unnecessary tests — something Bond said providers can underestimate. “The cost of these tests becomes very much of a strain on our patient populations just in terms of copayment and things of that nature,” Bond said. When a low-risk ECG reading helps confirm that an echocardiogram isn’t necessary, it can also spare a patient the hours off work and the child care and transportation needed for one more appointment, she said. Diagnosis often depends on whether a patient is referred for an echocardiogram in the first place, and who gets those referrals is uneven, said Aaron Horne , MD, a cardiologist and co-chair of...

More: FDA Clears AI Tool to Spot Cardiovascular Disease Risk Ahead of Symptoms. Pathway Labs has shared five of them: right-sided heart failure left-sided heart failure valve disease severe thickening of the heart muscle pulmonary hypertension These conditions often build quietly.

TL;DR: A first-of-its-kind AI tool was cleared by the FDA to detect underlying structural heart disease before symptoms present.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jun 29, 09:54

GLP-1s Like Ozempic, Mounjaro Linked to Reduced Stroke, Heart Risks

A growing body of evidence shows that GLP-1 drugs benefit cardiovascular health. Image Credit: Healthline/Munro/Getty Images GLP-1 medications like Ozempic and Wegovy help protect heart health, but stopping the medications may reduce the protective effects. Some research suggests that GLP-1s containing tirzepatide (Zepbound, Mounjaro) may help lower the risk of further complications in people with cardiovascular disease. Other research suggests that GLP-1s may help reduce thromboembolic events, such as deep vein thrombosis (DVT), in people with obesity and autoimmune diseases. GLP-1 medications were originally developed for the management of type 2 diabetes . Now, GLP-1 medications , such as Ozempic , Wegovy , and Mounjaro , are widely prescribed for weight management in people with overweight or obesity. A large body of evidence shows that GLP-1s offer health benefits beyond diabetes and weight loss. Recent research published in  BMJ Medicine suggests that GLP-1 medications may support heart health, with cardiovascular benefits increasing with longer duration of use. However, stopping the medication may reduce heart-protective benefits. Findings presented at the  SCAI 2026 Scientific Sessions & CAIC-ACCI Summit  in Montreal in April indicate that GLP-1 medications containing tirzepatide ( Mounjaro and Zepbound ) may help lower the risk of heart problems in people with  obesity undergoing certain heart procedures. A research article in the Journal of the American Heart Association (JAHA) explored additional benefits of GLP-1 drugs, with some findings suggesting a reduced risk of thromboembolic events, such as DVT and pulmonary embolism. Tirzepatide GLP-1s lower risk of heart procedure complications Two studies on the potential benefits of the GLP-1 receptor agonist tirzepatide were presented at the  SCAI 2026 Scientific Sessions & CAIC-ACCI Summit  in Montreal in April. The studies have not yet been published in a peer-reviewed scientific journal, but a news release detailed some of these findings. GLP-1s containing tirzepatide may reduce the risk of major heart problems like stroke by 30% in people with obesity who’ve undergone a heart procedure known as a transcatheter aortic valve replacement (TAVR) . Tirzepatide GLP-1s may also reduce the risk of mortality by 62% in people with type 2 diabetes who undergo a percutaneous coronary intervention (PCI) procedure compared with those taking dulaglutide. “These findings are consistent with what we are seeing broadly that medications like tirzepatide are not just weight loss drugs but have meaningful cardiometabolic benefits,” said Kevin Shah , MD, a cardiologist and the program director of Heart Failure Outreach at MemorialCare Heart & Vascular Institute at the Long Beach Medical Center, in a previous interview with Healthline. Shah wasn’t involved in the studies. Stopping GLP-1 treatment may reduce heart benefits GLP-1 medications may reduce the risk of heart disease. However, once you stop taking the medication, the protection may be reversed, according to research published in  BMJ Medicine in March. The research suggests that, while continued use may increase heart benefits over time, stopping the medication may reduce or reverse those benefits. The study followed 132,551 people taking GLP-1 medication and 201,136 people taking sulfonylurea for 3 years to treat diabetes. It noted that 26.36% of people discontinued GLP-1 treatment, most commonly during the first year. As the study found that GLP-1 medications are more likely to provide heart health protection over time, stopping treatment earlier means they are less likely to offer these benefits. “The main message is that GLP-1 therapy behaves more like a long-term risk-reduction treatment than a short-term fix,” said   Robert Glatter , MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hospital in New York City, and assistant professor of Emergency Medicine at Zucker School of Medicine at Hofstra/ Northwell, in a previous interview . Glatter was not involved in the study. “The study reinforces a broader lesson in chronic disease management: benefits that accumulate slowly can be lost surprisingly fast when treatment is interrupted, so persistence and follow-up truly matter,” he told Healthline. GLP-1s help lower risk of thromboembolic events Research published in June found that GLP-1 use was associated with fewer thromboembolic events, such as venous thromboembolism and pulmonary embolism , in adults with obesity and autoimmune diseases . “GLP-1 receptor agonists are increasingly recognized as having effects that extend beyond weight loss and glucose control,” said Christopher Yi , MD, board certified vascular surgeon at MemorialCare Orange Coast Medical Center in Fountain Valley, CA. Yi wasn’t involved in the study. “They reduce systemic inflammation, improve metabolic health, and may improve endothelial function — all mechanisms that could plausibly reduce thromboembolic r...

More: GLP-1s Like Ozempic, Mounjaro Linked to Reduced Stroke, Heart Risks. Image Credit: Healthline/Munro/Getty Images GLP-1 medications like Ozempic and Wegovy help protect heart health, but stopping the medications may reduce the protective effects. Stopping GLP-1 treatment may reduce heart benefits GLP-1 medications may reduce the risk of heart disease.

TL;DR: A growing body of evidence shows that GLP-1 drugs benefit cardiovascular health.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 27, 13:53

Just 2 Hours of Strength Training May Lower Heart Disease Risk in Women

Research shows that 2 hours of weekly strength training may help reduce the risk of cardiovascular disease in women. Image Credit: COROIMAGE/Getty Images A new study suggests that women who do at least 2 hours of strength training per week have a lower risk of cardiovascular disease.  The findings add that women who perform 150 minutes of weekly aerobic exercise and at least 2 hours of weekly strength training have a lower risk of heart attack.  Strength training is considered highly beneficial both during and after menopause. There are many well-known benefits of strength training, including stronger bones and muscles, improved heart health, and decreased abdominal fat.  A new study suggests that women who engage in more strength training during midlife and beyond have a lower risk of cardiovascular disease than those who do not. The findings, published on June 17 in JACC , the flagship journal of the American College of Cardiology, show that heart health benefits increased when strength training was paired with aerobic exercise.  Cardiovascular disease remains the leading cause of death worldwide. This makes accessible prevention strategies even more important.  “Beyond heart disease, resistance training uniquely addresses osteoporosis by improving bone mineral density at the femoral neck and lumbar spine, frailty due to muscle loss, and fall risk, which are all conditions that disproportionately affect postmenopausal women,” said Mary Greene , MD, board certified cardiologist with Manhattan Cardiology in NYC. Greene wasn’t involved in the study. “This makes resistance training a particularly high-value intervention in this population, [as it addresses] multiple morbidities simultaneously.” Strength training lowers heart disease risk by 20% The study analyzed 117,025 females from the Nurses’ Health Study and Nurses’ Health Study II, with average baseline ages of 66.8 and 48.1 years, respectively. The researchers assessed strength training every 4 years, with arm and leg training reported separately. The primary measure of sedentary behavior was time spent watching TV. This was assessed by averaging hours per week spent sitting at home watching TV. The primary outcome was measured in incidents of major cardiovascular disease. This was defined as: fatal or nonfatal myocardial infarction (heart attack) stroke coronary artery bypass grafting percutaneous coronary intervention (PCI) In both groups of participants, higher levels of strength training were associated with a lower risk of major cardiovascular disease, especially heart attack. However, there was no significant association for stroke. “One possible explanation is that heart attacks and strokes do not arise through identical pathways,” said study co-authors Tianyue Zhang , MD, and Edward Giovannucci , MD. “Resistance training is thought to improve factors such as cholesterol and other blood lipids, insulin sensitivity, and overall body composition, all of which are strongly linked to coronary artery disease and myocardial infarction,” they told Healthline. “Stroke, however, is a more heterogeneous outcome that includes several subtypes, ischemic, hemorrhagic, and cardioembolic, which may not all respond in the same way to the physiological changes associated with resistance training. In addition, we cannot fully exclude the role of chance, so these subtype‑specific differences should be interpreted with some caution,” the study authors explained.  Females who did 2 or more hours of strength training per week had a 20% lower risk of cardiovascular disease than those who did none.  Each additional hour of strength training per week was associated with a 5% lower risk of major cardiovascular disease and 14% lower risk of heart attack. These associations weakened after adjustments for body mass index (BMI) and cardiometabolic conditions, such as diabetes , high blood pressure , and high cholesterol . However, the researchers say the associations remained clear.  “[The findings] fit with what we know about the metabolic effects of maintaining muscle, including better insulin sensitivity, healthier body composition, and improved blood pressure control,” said Rigved Tadwalkar , MD, consultative cardiologist and director of Digital Transformation Pacific Heart Institute in Santa Monica, CA. Tadwalkar wasn’t involved in the study.  “I would not tell a patient that lifting weights guarantees a 20% reduction in risk, since this was an observational study. However, I would tell her that strength training now has a stronger cardiovascular case than many people realize,” he told Healthline. Strength training, aerobic exercise lower heart attack risk by 45% The researchers found that strength training provided additional benefits when combined with regular aerobic exercise.  Females who did 2 or more hours of weekly strength training along with 150 minutes of weekly aerobic exercise had a 45% lower risk of heart attack than those with no physical acti...

More: Just 2 Hours of Strength Training May Lower Heart Disease Risk in Women. Greene wasn’t involved in the study. Tadwalkar wasn’t involved in the study.  “I would not tell a patient that lifting weights guarantees a 20% reduction in risk, since this was an observational study.

TL;DR: Research shows that 2 hours of weekly strength training may help reduce the risk of cardiovascular disease in women.

Read original at Healthline →

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Healthline Jun 26, 17:29

Can GLP-1 Weight Loss Drugs Give Athletes an Unfair Advantage?

GLP-1 drugs can provide benefits that may boost an athlete’s performance, but do these medications give them the competitive edge? Getty Images/The Good Brigade Debates are emerging over whether GLP-1 drugs boost athletic performance . However, experts say the loss of lean mass associated with using these drugs may cancel out any competitive advantages. They say it’s essential to consider the legitimate medical uses of these medications before setting policy. More data is needed before sports organizations can make a decision that protects both athletes and sports. When do medications cross over from being about better health to providing an unfair boost to athletic performance? As more and more people, including well-known athletes like tennis champion Serena Williams, use popular GLP-1 drugs like Wegovy and Mounjaro (her medication of choice), to lose weight and get back in shape, this question is being asked more frequently. “I’ve got more energy for my workouts,” Williams proclaims in advertising for tele-health company Ro , with Ro further adding that it “helped her get back to her strongest self.” But is that just adspeak? Or do GLP-1s actually give athletes a physical advantage over those who don’t use them? Williams herself told Women’s Health that, “Being on a GLP-1 definitely doesn’t take away from who I am as a professional athlete. “In fact, I am enjoying sports now more than ever. And my body feels good doing it,” she added, noting that she would “never take a shortcut to living a healthy life.” How can GLP-1 drugs give athletes a performance boost? Sergio Guiteau , MD, a board certified family and sports medicine physician and Medical Director at South Florida Advanced Rejuvenation, in Miramar, Florida, said that there are benefits to be had from GLP-1s, including improvements in insulin resistance and body fat composition, as well as weight loss. There can also be indirect improvements in energy, mood, and endurance, he noted. “While these improvements may not be as pronounced as other PED’s [ performance enhancing drugs ], I certainly see some advantage for athletes using GLP-1’s,” said Guiteau. Going on to explain what constitutes a PDE, he said that the World Anti-Doping Agency (WADA), an independent international body aimed at developing and overseeing anti-doping rules and policies in sports, deems a substance to be a PED if: It has the potential to enhance or actually does enhance sports performance It represents an actual or potential health risk to athletes It “violates the spirit of sport.” When it comes to GLP-1s, Guiteau said he believes that the first requirement is met. Additionally, there may be some limited risk to healthy athletes. “Point 3 will likely be met at a point in time where an athlete utilizes a GLP-1 in a manner that results in a high achievement that was met with the use of the GLP-1 to enhance that athlete’s ability to achieve the result,” he said. As an example, Guiteau described a case where an athlete might use a GLP-1 to cut weight, giving them an edge during competitions such as cycling or horse racing. However, he added that “violates the spirit of sport” is a vague term and open to interpretation. “GLP-1 products can be considered substances that modify body composition, which can result in a change in performance as opposed to strictly performance enhancing,” he said. However, there’s no evidence at this time that GLP-1 medications give any direct competitive advantage, according to Guiteau. Any benefits of GLP-1s may be cancelled out by the loss of lean mass Karthik Achari , DNP-FNP(c), founder and CEO of PepMD, said that the strongest argument against GLP-1s being PEDs is the fact that the drugs would likely harm athletic performance more than they would help. “About 25 to 35% of the weight lost on GLP-1s is lean mass,” he explained. “For an athlete whose performance depends on power, explosiveness, and strength, that’s a real cost that may offset the body composition benefit entirely.” This occurs, he said, because people on GLP-1s don’t selectively burn fat. Instead, the body draws from both fat and muscle. “An athlete who is lighter but weaker isn’t necessarily a better athlete,” said Achari. Another concern is that elite athletes often need a large number of calories to support their intensive training regimens and recovery. “Appetite suppression and delayed gastric emptying make that intake genuinely difficult,” he said, adding that recovery is especially important since this is when the adaptations that lead to improvement in performance occur. Achari further noted the lack of direct scientific evidence, since most trials have included patients with obesity and diabetes, not elite athletes. “Extrapolating from ‘this drug helps a sedentary obese patient lose weight’ to ‘this drug improves elite athletic performance’ is a longer logical jump than the popular debate acknowledges,” he said. Achari added that improvements seen by athletes like Serena...

More: Can GLP-1 Weight Loss Drugs Give Athletes an Unfair Advantage?. Williams herself told Women’s Health that, “Being on a GLP-1 definitely doesn’t take away from who I am as a professional athlete. “About 25 to 35% of the weight lost on GLP-1s is lean mass,” he explained.

TL;DR: GLP-1 drugs can provide benefits that may boost an athlete’s performance, but do these medications give them the competitive edge?

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jun 26, 17:03

COVID Vaccine Study Previously Blocked By CDC Is Out — Here's What It Found

A study on COVID-19 vaccines that was previously blocked by the CDC’s acting director was published in a medical journal. luis velasco/Stocksy A COVID-19 vaccine efficacy study that had previously been blocked by the CDC was published in a scientific journal. Acting CDC Director Jay Bhattacharya blocked the study from appearing in the CDC’s Morbidity and Mortality Weekly Report (MMWR), prompting months of criticism. The study affirmed that COVID-19 vaccines reduced the risk of hospitalization and severe illness among older adults, reinforcing the safety and effectiveness of vaccination against the disease. A study on COVID-19 vaccines that was delayed and ultimately blocked from publication by the acting director of the Centers for Disease Control and Prevention (CDC) was published this week in a medical journal. The study, originally slated for publication in an edition of the CDC’s Morbidity and Mortality Weekly Report (MMWR) , concluded that COVID-19 vaccines reduced the likelihood of COVID-19 -related hospitalization and severe illness among adults by about half. The research was published on June 23 in JAMA Network Open .  The study’s publication arrives months after the Washington Post first reported that it had been blocked in April. Acting CDC Director Jay Bhattacharya questioned the study’s methodology after it had already completed scientific review and received editorial approval.  The controversy around the study has extended beyond the findings. Rather than centering on whether the updated vaccine provided protection, much of the debate has focused on the research method used to measure vaccine effectiveness. However, experts say that nothing in the study, nor its design, was significant enough to warrant its being pulled. “There are legitimate reasons to pause — a serious error, a data problem, conclusions that go further than the evidence supports,” said Robert Glatter , MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hospital in New York City, and assistant professor of Emergency Medicine at Zucker School of Medicine at Hofstra/ Northwell. Glatter wasn’t involved in the study. “But the fix for all of those is the open scientific process: revise, respond to reviewers, replicate. Quietly halting accepted research without a transparent scientific reason falls outside how regulators are supposed to operate,” he told Healthline. Blocked COVID study reaffirms vaccine efficacy The newly published study examined adults who sought medical care for COVID-19-like illness across hospitals and emergency departments in seven states. Researchers found that adults who received the updated 2025-2026 COVID-19 vaccine were substantially less likely to require emergency, urgent, or inpatient care for COVID-19 than comparable adults who had not received that season’s vaccine. It also addresses whether seasonal COVID-19 vaccines provide meaningful benefit after previous vaccinations and infections. “It really reinforces the message that COVID is still with us, and the vaccine provides substantial, not perfect, but substantial protection against more serious illness, and most importantly, reduces your risk of hospitalization,” said William Schaffner , MD, professor of preventive medicine and infectious diseases in the Department of Health Policy at Vanderbilt University Medical Center. Schaffner wasn’t involved in the study. Glatter said the study’s design makes the findings especially relevant because it reflects the reality that most adults already have some degree of immunity. “The real message isn’t ‘the vaccine is 50% effective, period.’ It’s that even if you’ve had COVID in the near or distant past, and been vaccinated before, the current vaccine still measurably reduces your odds of getting sick enough to require medical attention,” he said. Updated COVID vaccines still offer protection The study analyzed data from the CDC-funded Virtual SARS-CoV-2, Influenza, and Other Respiratory Viruses (VISION) Network , which links electronic health records and vaccination records across seven states. Researchers evaluated adults ages 18 years and older with healthy immune functioning who sought medical care for COVID-19-like illness between September and December 2025. The study used a test-negative case-control design, comparing patients who tested positive for SARS-CoV-2, the virus that causes COVID-19, with people who sought care for similar respiratory symptoms but tested negative. Among 85,725 emergency department and urgent care encounters, researchers identified 3,941 COVID-19 cases and 81,784 controls. Among those who tested positive, 5% had received the updated vaccine, compared with 12% among those who tested negative. After adjusting for factors including age, sex, and ethnicity, the researchers estimated the updated vaccine reduced the risk of COVID-19-associated emergency department or urgent care visits by 50%. The vaccine also reduced the risk of COVID-19-related hospit...

More: COVID Vaccine Study Previously Blocked By CDC Is Out — Here's What It Found. A study on COVID-19 vaccines that was previously blocked by the CDC’s acting director was published in a medical journal. The vaccine also reduced the risk of COVID-19-related hospit...

TL;DR: Glatter wasn’t involved in the study.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Sciencedaily Jun 26, 03:07

Omega-3 fish oil shows promise against type 2 diabetes

A new study suggests fish oil may help reduce insulin resistance even in people who aren't obese. In diabetic rats, omega-3 supplementation improved blood sugar levels, cholesterol, and inflammation by shifting immune cells into a more anti-inflammatory mode.

More: Omega-3 fish oil shows promise against type 2 diabetes. A new study suggests fish oil may help reduce insulin resistance even in people who aren't obese. In diabetic rats, omega-3 supplementation improved blood sugar levels, cholesterol, and inflammation by shifting immune cells into a more anti-inflammatory mode.

TL;DR: A new study suggests fish oil may help reduce insulin resistance even in people who aren't obese.

Read original at Sciencedaily →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 25, 17:14

Can GLP-1 Drugs Like Ozempic Really Change Your Sense of Smell and Taste?

Some GLP-1 users report changes in their taste and smell, according to a new study. Tatsiana Volkava/Getty Images Researchers report that GLP-1 drugs used to treat type 2 diabetes may impair a person’s sense of taste and smell. Experts say taste and smell dysfunction doesn’t appear to be a common side effect of GLP-1s, which are widely prescribed for weight loss. The weight loss benefits of these medications likely outweigh any negative effects on smell and taste. GLP-1 medications prescribed to treat type 2 diabetes may affect a person’s sense of smell and taste, according to a new study. Researchers report that study participants who used GLP-1 drugs had a higher rate of disturbances in taste and smell than people who were only prescribed diabetes medications . They said the effects of GLP-1s on these sensory functions could be connected to the drugs’ absorption into a person’s nervous system. “This study suggests that GLP-1RA therapy is associated with a higher risk of smell and taste disturbance, highlighting the need for closer monitoring and greater public health awareness,” the study authors wrote. “Future research is required to validate these findings and to further explore the mechanisms underlying this association,” they added. The researchers published their findings on June 25 in the journal JAMA Otolaryngology – Head & Neck Surgery . Experts say that loss of smell or taste from GLP-1 medications doesn’t appear to be widespread. Mir Ali , MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California, said he hasn’t heard many concerns from his patients about taste or smell impairment. Ali wasn’t involved in the study. “I don’t think it should discourage people from taking these medications,” he told Healthline. “The trade-off of getting to a healthy weight far outweighs any changes to taste or smell.” GLP-1s linked to taste, smell dysfunction For their study, the researchers examined the medical records of two groups of participants in the  TriNetX Global Collaborative Network program , which involved more than 170 healthcare institutions from December 2017 to April 2026. Each group consisted of more than 430,000 adults with a diagnosis of  type 2 diabetes  who had no history of taste or smell impairment. Participants in each group were about 55% female, with an average age of about 57 years. One group had been prescribed a GLP-1 medications after their diabetes diagnosis. The other group was prescribed a diabetes medication but did not use any GLP-1 drugs. GLP-1 medications approved to treat type 2 diabetes include:  Ozempic Rybelsus Mounjaro Trulicity There was a follow-up period of 3 months to 2 years after the discontinuation of the use of GLP-1 medications. The researchers reported that taste disturbances were identified in 769 participants in the GLP-1 group, compared with 445 in the control group. Smell disturbances were reported by 649 participants in the GLP-1 group, compared with 316 in the control group. The researchers said that the smell and taste dysfunction could be related to the olfactory bulb and chemosensory pathways. “These findings align with evidence that GLP-1 is widely expressed and secreted within the nervous system, supporting potential effects in either the central or peripheral nervous system,” the researchers wrote. Ali said weight loss can affect a person’s sense of taste and smell. He added that there aren’t really any treatments for temporary smell and taste dysfunction. “As weight stabilizes, taste and smell tend to return to a more normal state,” he said. Zhaoping Li , MD, a professor of clinical medicine at the University of California, Los Angeles, noted the new study is observational and doesn’t prove a cause-and-effect relationship between GLP-1s and impaired taste and smell. Li wasn’t involved in the study. Li shared that her patients have not encountered serious smell or taste dysfunction. “It has not been a major issue,” she told Healthline. “I don’t think it will have a major impact on people’s acceptance of these drugs.” Li said that taste and smell impairment caused by the medication has a simple solution. “If it is related to the drugs, then you stop taking the drugs,” she said. Why your sense of smell and taste matters It’s estimated that 12% of people in the United States have some sort of smell dysfunction. That percentage is higher in older age groups. Experts say smell has many important functions. They say it helps people determine what to eat, influences food taste, and affects socialization. Smell also provides a warning for hazardous events such as fires or gas leaks. The sense of smell is connected to the part of the brain involved in behavioral and emotional responses. That’s why certain odors spark strong emotions, influence behavior, and trigger memories, according to  UCLA Health . Impaired smell can be the complete inability to smell or the partial inability ...

More: Can GLP-1 Drugs Like Ozempic Really Change Your Sense of Smell and Taste?. The weight loss benefits of these medications likely outweigh any negative effects on smell and taste. Researchers report that study participants who used GLP-1 drugs had a higher rate of disturbances in taste and smell than people who were only prescribed diabetes medications .

TL;DR: Some GLP-1 users report changes in their taste and smell, according to a new study.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Nutritionletter Jun 25, 15:27

Download the Full July 2026 Issue PDF

Outdoor Food Safety NewsBites: Organic vs. synthetic vitamins and minerals; introducing food allergens; vitamin D and brain health. New Cholesterol Guidelines Special Report: Everyday Habits for Brain Health Container Gardening Featured Recipe: Grilled Balsamic Chicken Ask Tufts Experts: Are my tastebuds changing? The post Download the Full July 2026 Issue PDF appeared first on Tufts Health & Nutrition Letter .

More: Download the Full July 2026 Issue PDF. New Cholesterol Guidelines Special Report: Everyday Habits for Brain Health Container Gardening Featured Recipe: Grilled Balsamic Chicken Ask Tufts Experts: Are my tastebuds changing? The post Download the Full July 2026 Issue PDF appeared first on Tufts Health & Nutrition Letter .

TL;DR: synthetic vitamins and minerals; introducing food allergens; vitamin D and brain health.

Read original at Nutritionletter →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Nutritionletter Jun 25, 15:26

No Difference Found Between Organic and Synthetic Vitamins/Minerals

Some theorize that organic supplements may be more effective at raising blood levels of vitamins and minerals than synthetic formulations. A randomized controlled trail published in the journal Current Developments in Nutrition in April of 2026 found this is not the case. Organic vitamins are derived from organically grown foods or from algae or microorganisms. […] The post No Difference Found Between Organic and Synthetic Vitamins/Minerals appeared first on Tufts Health & Nutrition Letter .

More: Some theorize that organic supplements may be more effective at raising blood levels of vitamins and minerals than synthetic formulations. A randomized controlled trail published in the journal Current Developments in Nutrition in April of 2026 found this is not the case. Organic vitamins are derived from organically grown foods or from algae or microorganisms.

TL;DR: […] The post No Difference Found Between Organic and Synthetic Vitamins/Minerals appeared first on Tufts Health & Nutrition Letter .

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Nutritionletter Jun 25, 15:26

Early Introduction of Food Allergens May Reduce Allergy Risk

Peanuts are one of the most common causes of serious food allergy in children. While parents were once instructed to avoid exposing infants and young children to peanuts and peanut products, the most recent guidelines recommend the introduction of peanut, egg, and other major food allergens at age four to six months. This major shift […] The post Early Introduction of Food Allergens May Reduce Allergy Risk appeared first on Tufts Health & Nutrition Letter .

More: Early Introduction of Food Allergens May Reduce Allergy Risk. Peanuts are one of the most common causes of serious food allergy in children. While parents were once instructed to avoid exposing infants and young children to peanuts and peanut products, the most recent guidelines recommend the introduction of peanut, egg, and other major food allergens at age four to six months.

TL;DR: This major shift […] The post Early Introduction of Food Allergens May Reduce Allergy Risk appeared first on Tufts Health & Nutrition Letter .

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Nutritionletter Jun 25, 15:26

Midlife Vitamin D Levels Associated with Measure of Later-Life Brain Health

Having low blood levels of vitamin D (<20 ng/mL) in later life has been associated with higher risk of cognitive impairment and dementia, including Alzheimer’s disease. A study published in April of 2026 in Neurology Open Access found that vitamin D levels in midlife also were associated with later-life brain health. To continue reading this […] The post Midlife Vitamin D Levels Associated with Measure of Later-Life Brain Health appeared first on Tufts Health & Nutrition Letter .

More: Midlife Vitamin D Levels Associated with Measure of Later-Life Brain Health. Having low blood levels of vitamin D (<20 ng/mL) in later life has been associated with higher risk of cognitive impairment and dementia, including Alzheimer’s disease.

TL;DR: To continue reading this […] The post Midlife Vitamin D Levels Associated with Measure of Later-Life Brain Health appeared first on Tufts Health & Nutrition Letter .

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Nutritionletter Jun 25, 15:26

Protect Your Heart: New Cholesterol Guidelines

On average, someone in the U.S. dies of cardiovascular disease every 34 seconds. Dyslipidemia—abnormal levels of cholesterol, triglycerides, and other lipids or lipoproteins in the blood—raises risk for cardiovascular disease and is, therefore, a major contributor to these deaths, as well as to non-fatal heart attacks and strokes. To continue reading this article or issue […] The post Protect Your Heart: New Cholesterol Guidelines appeared first on Tufts Health & Nutrition Letter .

More: Protect Your Heart: New Cholesterol Guidelines. dies of cardiovascular disease every 34 seconds. Dyslipidemia—abnormal levels of cholesterol, triglycerides, and other lipids or lipoproteins in the blood—raises risk for cardiovascular disease and is, therefore, a major contributor to these deaths, as well as to non-fatal heart attacks and strokes.

TL;DR: To continue reading this article or issue […] The post Protect Your Heart: New Cholesterol Guidelines appeared first on Tufts Health & Nutrition Letter .

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Nutritionletter Jun 25, 15:26

Everyday Habits for 
Brain Health

Aging brings inevitable changes throughout the body—including the brain. Over time, many people notice they don’t feel as sharp as they once were. They have more trouble finding words, can’t remember why they walked into a room, or process information more slowly than they used to. Cognitive changes like these are a typical part of […] The post Everyday Habits for 
Brain Health appeared first on Tufts Health & Nutrition Letter .

More: Everyday Habits for 
Brain Health. Aging brings inevitable changes throughout the body—including the brain. Over time, many people notice they don’t feel as sharp as they once were.

TL;DR: Cognitive changes like these are a typical part of […] The post Everyday Habits for 
Brain Health appeared first on Tufts Health & Nutrition Letter .

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Further reading: EatRightWHO NutritionNutrition.govWikipedia

Nutritionletter Jun 25, 15:26

Container Gardening: Homegrown for Anyone

Container gardening is an excellent way to grow your own food. It’s ideal for small spaces, takes little time, effort, and money, and is perfect for beginners. Easier to maintain than in-ground gardens, with no weeds and fewer pests, container gardens bring a homegrown harvest of healthy and delicious veggies, fruits, and herbs to your […] The post Container Gardening: Homegrown for Anyone appeared first on Tufts Health & Nutrition Letter .

More: Container Gardening: Homegrown for Anyone. It’s ideal for small spaces, takes little time, effort, and money, and is perfect for beginners. Easier to maintain than in-ground gardens, with no weeds and fewer pests, container gardens bring a homegrown harvest of healthy and delicious veggies, fruits, and herbs to your […] The post Container Gardening: Homegrown for Anyone appear…

TL;DR: Container gardening is an excellent way to grow your own food.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Nutritionletter Jun 25, 15:26

Taste Changes with Age

Q:  I feel like my taste is changing 
as I age. Why is this? A:  Judith C. Thalheimer, RD, LDN, executive editor of Tufts Health & Nutrition Letter, answers: To continue reading this article or issue you must be a paid subscriber. Sign in Subscribe Subscribe to Tufts Health & Nutrition Get the next year […] The post Taste Changes with Age appeared first on Tufts Health & Nutrition Letter .

More: Q:  I feel like my taste is changing 
as I age. Thalheimer, RD, LDN, executive editor of Tufts Health & Nutrition Letter, answers: To continue reading this article or issue you must be a paid subscriber. Sign in Subscribe Subscribe to Tufts Health & Nutrition Get the next year […] The post Taste Changes with Age appeared first on Tufts Health & Nutrition Letter .

TL;DR: Sign in Subscribe Subscribe to Tufts Health & Nutrition Get the next year […] The post Taste Changes with Age appeared first on Tufts Health & Nutrition Letter .

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Further reading: Nutrition.govPubMed NutritionWHO NutritionWikipedia

Nutritionletter Jun 25, 15:26

Outdoor Food Safety

Picnics and cookouts are great ways to get outside and enjoy the warm, sunny weather on July 4th or anytime this summer, but food sitting out in hot temperatures can increase the risk of foodborne illness. A few food safety measures during food preparation, storage, cooking, and serving can help minimize this risk. Be Aware. […] The post Outdoor Food Safety appeared first on Tufts Health & Nutrition Letter .

More: Picnics and cookouts are great ways to get outside and enjoy the warm, sunny weather on July 4th or anytime this summer, but food sitting out in hot temperatures can increase the risk of foodborne illness. A few food safety measures during food preparation, storage, cooking, and serving can help minimize this risk.

TL;DR: […] The post Outdoor Food Safety appeared first on Tufts Health & Nutrition Letter .

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 25, 12:24

Intermittent Fasting Aids Weight Loss, With a Surprising Psychological Benefit

Researchers compared intermittent fasting with calorie counting and found that people following fasting protocols thought about food less often. Anchiy/Getty Images A recent study found that people who bounce from one diet to another — or “yo-yo dieters” — may have better results following an intermittent fasting diet plan. The study compared intermittent fasting to traditional calorie counting for weight loss.  The results suggest that people following intermittent fasting experienced psychological benefits related to food. Over the last few years, intermittent fasting (IF) has become a popular diet plan for people looking to lose weight. During intermittent fasting, you eat for a set number of hours or days, and then fast for the remainder. For example, if following the 16/8 Method , you would eat for 8 hours and fast for the remaining 16 hours of the day.  A new study found that following an intermittent fasting dietary plan may be more beneficial for people who tend to “yo-yo diet” — those who jump from one diet to another rather than following a lifelong healthy eating plan. The study compared intermittent fasting to traditional calorie counting . The findings showed that people following either diet lost about the same amount of weight. However, those who adhered to fasting protocols experienced psychological and behavioral benefits, feeling they didn’t need to monitor overeating or count calories to lose weight. The study was published on July 16 in Clinical Nutrition . “Many chronic dieters become trapped in a cycle of constantly tracking, counting, restricting, and thinking about food,” said Monique Richard , MS, a registered dietitian nutritionist and owner of Nutrition-In-Sight, who wasn’t involved in the study. “If a structured eating window helps simplify decisions and reduce decision fatigue, that may improve long-term adherence for some people,” Richard told Healthline. Intermittent fasting led to fewer thoughts about food The study analyzed data from more than 200 people with obesity . Participants were randomly split into three groups: intermittent fasting traditional calorie counting standard balanced diet People following the intermittent fasting diet were asked to eat only between 8 a.m. and 12 p.m., then fast for 20 hours. This cycle took place three times a week on non-consecutive days.  Those following the calorie counting diet were asked to eat 70% of their usual diet, and those on a standard balanced diet didn’t have any restrictions. The researchers found that people following the intermittent fasting and calorie-counting diets lost about the same amount of weight.  However, those in the intermittent fasting group reported said they felt that they didn’t need to make major changes to their eating behaviors — such as monitoring overeating or counting calories — in order to lose weight. “Previous research shows that people who improve their relationship with food and gain better control over cravings lose more weight — regardless of the specific diet they undertake,” said lead study author Leonie Heilbronn , PhD, professor and clinical research scientist in the School of Medicine at Adelaide University in Australia. “What our study suggests is that we may be able to better personalize diet recommendations. If someone finds it difficult to improve eating behaviors, intermittent fasting might be better to help them still lose weight,” Heilbronn told Healthline. Is intermittent fasting for everyone? Although intermittent fasting is a popular diet, experts agree that it’s not for everyone.  “Intermittent fasting may not be the best for people with certain medical conditions like diabetes and things like that, where maybe they’re on medication (or) their blood sugar may go too low,” said Mir Ali , MD, bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA. Ali wasn’t involved in the study.  “It’s best to start with their primary doctor, see if that’s a reasonable approach to dieting for them with their medical concerns,” he told Healthline. Richard said intermittent fasting is also not an appropriate diet for those who are:  nursing growing adolescents living with a history of eating disorders pregnant taking medications that affect blood glucose “The best dietary pattern is rarely the one that produces the fastest weight loss — it’s the one a person can realistically sustain while meeting nutritional needs, supporting metabolic health, and maintaining a healthy relationship with food,” Richard said. Getting started with intermittent fasting For some people, Richard explained, intermittent fasting may simplify eating decisions. Creating clear boundaries around when you eat, rather than requiring continuous calorie calculations and monitoring throughout the day, can help make diet adherence feel less rigid.   “Constantly monitoring, counting, and evaluating food choices can create what some refer to as...

More: Intermittent Fasting Aids Weight Loss, With a Surprising Psychological Benefit. The findings showed that people following either diet lost about the same amount of weight. “What our study suggests is that we may be able to better personalize diet recommendations.

TL;DR: Researchers compared intermittent fasting with calorie counting and found that people following fasting protocols thought about food less often.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 24, 15:16

GLP-1s for $50 a Month? 14 Million Medicare Recipients May Be Eligible

An estimated 14 million Medicare Part D recipients could obtain Wegovy, Foundayo, and Zepbound for $50 per month. Johner Images/Getty Images Federal officials announced the launch of a Medicare GLP-1 Bridge pilot program that reduces the cost of certain GLP-1 medications prescribed for weight loss. Under the program, Wegovy, Foundayo, and Zepbound KwikPens will cost $50 per month for eligible participants enrolled in Medicare Part D plans. The program begins on July 1 and continues through Dec. 31, 2027. Some Medicare recipients will soon be able to purchase a limited number of GLP-1 weight loss drugs at a guaranteed price of $50 per month. The Department of Health and Human Services (HHS) recently announced the formation of the  Medicare GLP-1 Bridge  pilot program, which begins on July 1 and lasts until December 31, 2027. Under the pilot project, people enrolled in  Medicare Part D  who have been prescribed certain GLP-1 medications will be able to purchase those drugs for $50 per month. It’s estimated that around  14 million people  in the United States could be eligible under the pilot program. Federal officials note that in the past, Medicare has not covered medications prescribed for weight loss. The pilot program lifts that restriction. “These treatments are a major medical advancement, but too many seniors are currently unable to access them due to high cost,”  Mehmet Oz , MD, the administrator of the Centers for Medicare and Medicaid Services, said in a  statement . “The Medicare GLP-1 Bridge changes that by making these medications more affordable and accessible, while advancing our broader goal of helping Americans live healthier lives.” The Medicare Bridge program follows the launch last year of a Trump Rx program to lower the cost of GLP-1 medications and other higher-cost drugs. Which GLP-1s are covered and how much will they cost? To be eligible for the Medicare GLP-1 Bridge program, a person must be at least 18 years old and be treated with the GLP-1 medication for weight loss and weight management. The medications covered under the pilot program are: Wegovy  (both injections and tablets) Zepbound  (KwikPen) Foundayo Zepbound single-use pens and vials will be not be covered. To be prescribed these medications, a person must meet one of the following criteria: a body mass index ( BMI ) measurement of 35 or higher a BMI of 30 or higher with certain comorbid health conditions (i.e., heart failure , uncontrolled hypertension , or chronic kidney disease ) a BMI of 27 or higher with other health risks (i.e., prediabetes or peripheral artery disease ) Medicare currently covers GLP-1 drugs prescribed for the treatment of certain conditions, such as type 2 diabetes and obstructive sleep apnea . Recipients who utilize the bridge pilot program will not be eligible for this current coverage. The $50 copays do not count toward the annual Part D deductible , which can be up to  $615  for 2026. These payments also won’t count toward the yearly Part D out-of-pocket spending cap, which is $2,100 in 2026. The cost of GLP-1 medications ranges from $149 per month from certain self-pay options to $1,349 per month. Will Medicare GLP-1 Bridge actually lower costs? Experts who spoke to Healthline said the Medicare pilot program will be helpful to a certain portion of the Medicare population. “The biggest benefit of this program is increased access,” said  Kanwar Kelley , MD, a specialist in otolaryngology head and neck surgery, obesity medicine, and lifestyle medicine, and the chief executive officer of Side Health in Orinda, CA. “These medications are a breakthrough for clinically significant weight loss for the improvement of conditions that are related to obesity ,” Kelley said. “However, in my practice, there are individuals that simply cannot afford the cost of these medications, even when insurance pays some of the cost. The bridge program, if it reaches its goal, will provide a road for patients to get started on these medications and get the help they need,” he continued. “I believe this is a viable option for Medicare patients seeking these types of medications,” said Mir Ali , MD, a bariatric surgeon, bariatric medicine specialist, and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California. “The primary benefit is the significant reduction in out-of-pocket costs for Medicare beneficiaries,” he said. Meredith Freed , a senior policy manager with KFF’s Program on Medicare Policy, agreed. “Overall, the new GLP-1 Bridge is good news for people with Medicare who might benefit from taking GLP-1s to treat obesity but who have been unable to access these medications due to Medicare’s coverage restrictions or the relatively high cost of these drugs,” she said. “At $50 per month, these drugs would be within reach for many more Medicare beneficiaries than they are today,” Freed added. Possible drawbacks GLP-1 drug pilot program The experts who s...

More: Under the pilot project, people enrolled in  Medicare Part D  who have been prescribed certain GLP-1 medications will be able to purchase those drugs for $50 per month. Federal officials note that in the past, Medicare has not covered medications prescribed for weight loss.

TL;DR: To be eligible for the Medicare GLP-1 Bridge program, a person must be at least 18 years old and be treated with the GLP-1 medication for weight loss and weight management.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Sciencedaily Jun 24, 03:14

Scientists say guava juice could make iron supplements work better

Researchers found that drinking guava juice may significantly improve anemia by helping the body absorb iron more efficiently. In a review of 17 studies, women and teenage girls who consumed guava juice — especially with iron supplements — experienced noticeable increases in hemoglobin levels. Since guava contains far more vitamin C than oranges, scientists believe it could become a simple, affordable nutrition tool in regions where anemia is widespread.

More: Scientists say guava juice could make iron supplements work better. In a review of 17 studies, women and teenage girls who consumed guava juice — especially with iron supplements — experienced noticeable increases in hemoglobin levels.

TL;DR: Researchers found that drinking guava juice may significantly improve anemia by helping the body absorb iron more efficiently.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 23, 18:53

HHS to Update Testosterone Therapy Labels for Prostate Cancer, Hypogonadism

HHS announced it would request updates to the warning labels for testosterone replacement therapy products. Malorny/Getty Images The Department of Health and Human Services (HHS) has proposed key changes to the labeling of testosterone replacement therapy (TRT) products. The proposed changes could expand access to TRT for men with idiopathic and age-related hypogonadism. According to HHS Secretary Robert F. Kennedy, Jr., the changes reflect the most current scientific evidence on the risks and benefits of TRT. The Department of Health and Human Services (HHS) announced plans on June 18 to update label information for testosterone replacement therapy (TRT) products, marking a significant shift in policy. The proposed changes would remove longstanding restrictions on TRT related to age-related hypogonadism , revise warnings about prostate cancer risk , and update safety information concerning benign prostatic hyperplasia (BPH), commonly known as an enlarged prostate . “During Men’s Health Month, we are putting science back at the center of men’s healthcare,” HHS Secretary Robert F. Kennedy Jr. said in the announcement. “By updating testosterone therapy labels to reflect current evidence, we are giving patients and physicians clearer information, supporting informed medical decisions, and improving care for millions of American men.” The announcement follows a December 2025 meeting of FDA experts , during which the panel signaled broad support for expanding access to TRT. In April, the FDA made an announcement encouraging manufacturers of approved TRT products to explore a potential new indication for low libido in males with idiopathic hypogonadism, or low testosterone without a known underlying cause. Currently, FDA-approved TRT products may only be prescribed for forms of hypogonadism with specific genetic or structural causes. Federal officials say the changes reflect a growing body of evidence supporting the safety and effectiveness of testosterone therapy when appropriately prescribed and monitored. For patients, the proposed updates could expand access to treatment while also clarifying risks based on the most up-to-date evidence. The announcement was supported by men’s health experts interviewed by Healthline, who agreed that TRT-associated cardiovascular, prostate cancer, and BPH risk have been overstated. 3 key revisions proposed for TRT labels The proposed labeling revisions focus on three major areas: age-related hypogonadism, prostate cancer risk, and BPH. The FDA is requesting the removal of a limitation stating that the safety and effectiveness of testosterone replacement therapy have not been established in males with age-related hypogonadism. The condition refers to the gradual decline in testosterone that can occur with aging, rather than due to an identifiable medical condition. That limitation was added in 2015 , when concerns arose about possible cardiovascular risks associated with testosterone therapy, and evidence supporting its use was considered limited. Since then, additional data have emerged, including the TRAVERSE trial , a large study involving more than 5,200 males. According to HHS, the trial found no meaningful increase in the risk of major adverse cardiovascular events, including heart attack and stroke , among males receiving testosterone replacement therapy. Based on its review of the TRAVERSE findings and other available evidence, the FDA concluded that the limitation is no longer warranted. Franck Mauvais-Jarvis , MD, PhD, a professor of medicine at Tulane University and director of the VA hormone therapy clinic at New Orleans Medical Center, called the decision “a very important victory.” Other experts said the findings reinforce what many men’s health experts have known for years. “Even before this trial had been conducted, it was well known in the men’s health community that testosterone replacement within physiologic ranges is safe and should not cause adverse cardiovascular events. This study reinforces this common knowledge,” said S. Adam Ramin , MD, board certified urologist, urologic oncologist, and medical director of Urology Cancer Specialists in Los Angeles, California. However, he emphasized that safety depends heavily on maintaining testosterone levels within the normal physiologic range. According to Ramin, clinicians should generally target testosterone levels between approximately 350 and 750 ng/dL. Super physiologic levels substantially above that range may increase red blood cell production and potentially raise the risk of blood clots , heart attack, or stroke. Ramin added that testosterone replacement has also been shown to be effective: consistently raising testosterone levels and improving symptoms associated with low testosterone. He noted that treatment may help prevent muscle loss and osteoporosis in appropriately selected individuals. “I am in agreement with the FDA removing this warning label. However, I would also suggest that healthcare pr...

More: HHS to Update Testosterone Therapy Labels for Prostate Cancer, Hypogonadism. According to HHS, the trial found no meaningful increase in the risk of major adverse cardiovascular events, including heart attack and stroke , among males receiving testosterone replacement therapy.

TL;DR: The announcement was supported by men’s health experts interviewed by Healthline, who agreed that TRT-associated cardiovascular, prostate cancer, and BPH risk have been overstated.

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 23, 17:00

EMT Revives Knicks Fan With Narcan as FDA Expands Access to the Medication

NEW YORK, NEW YORK – JUNE 18: Fans cheer for the New York Knicks as a float with Karl-Anthony Towns and teammates pass by during the New York Knicks Championship ticker tape parade and victory rally celebrating winning the 2026 NBA Finals on June 18, 2026 in New York City. The New York Knicks defeated the San Antonio Spurs in five games to win their first NBA Championship in 53 years. (Photo by Caleb Bowlin/Getty Images) An off-duty EMT saved a man’s life with Narcan during an apparent overdose at the NY Knicks championship parade. The incident highlights the need for quick action with a naloxone medication during an opioid emergency. The FDA recently approved another OTC naloxone, further broadening access to this lifesaving medication. The New York Knicks championship parade drew an estimated 2 million fans to Lower Manhattan on June 18 in celebration of the team’s first NBA title in 53 years. While the gathering was largely festive, it was not without incident. Simone Kelly , 24, a volunteer emergency medical technician, was off-duty when she and another anonymous first responder used Narcan to revive a man who had apparently overdosed, according to the New York Post , which was first on the scene. The heroic act amidst a throng of bystanders quickly went viral, highlighting the need for a fast response to opioid overdoses with naloxone-based medications. Kelly said that “anyone can learn” how to step in during an opioid emergency. Here’s what you need to know about naloxone, and why it’s more accessible than ever. FDA broadens access to naloxone Narcan, an over-the-counter nasal spray, was approved by the Food and Drug Administration in 2023 to rapidly reverse opioid overdoses . On June 16, the FDA further expanded access to this lifesaving medication with another intranasal naloxone product, Rextovy, to help reduce opioid-related deaths in the United States. The FDA states that while overdose deaths have dropped dramatically since Narcan’s approval, the problem, largely driven by synthetic opioids like fentanyl , persists. “Reducing opioid overdose deaths is a top priority for FDA,” Mike Davis , MD, PhD, Acting Director of the Center for Drug Evaluation and Research (CDER), said in a statement . “Empowering people without medical training to take immediate action with these products has been proven to save lives.” Rextovy, is now available for purchase without a prescription at pharmacies, stores, and online. “This is significant because it means anyone can walk into a pharmacy and get a medication that can save their own or someone else’s life from an opioid overdose, no prescription needed,” said Joseph Volpicelli , MD, PhD, Executive Director of the Institute of Addiction Medicine, Emeritus Associate Professor of Psychiatry at the University of Pennsylvania, and senior advisor at Oar Health. “In the U.S., where opioids are [a] leading cause of injury-related death for people under 45, this expansion removes major barriers to addiction medication access, which I hope will set the precedent for similar drugs like naltrexone ,” he told Healthline. Fentanyl crisis spotlights need for fast response Overdose deaths from synthetic opioids like fentanyl account for upward of 92% of all fatal opioid overdoses. Synthetic, illicitly made opioids have become so potent that naloxone may not be enough to undo the harm of an overdose. Worse, fentanyl is now mixed into many different types of drugs, often without the user’s knowledge. A recent study published in Anesthesiology found that naloxone may not fully reverse respiratory depression caused by a synthetic opioid overdose, further highlighting the need for fast intervention. “Our study shows that the current doses of naloxone may not be sufficient to reverse overdoses caused by newer synthetic opioids,” study lead author Maarten A. van Lemmen , PhD, of the Department of Anesthesiology and Anesthesia and Pain Research Unit at Leiden University Medical Center in Leiden, the Netherlands, said in a statement . “We hope these findings encourage institutions to update guidelines and reinforce the importance of fast emergency intervention.” An accompanying editorial explains that when someone who’s overdosed gets naloxone, they may wake up and seem alert, even before their breathing has returned to normal. Their breathing could still be slow even though they’re responsive, which does not indicate they’ve recovered. “Many overdose victims become unconscious or marginally conscious with very slow breathing that is enough to deliver oxygen to the brain without causing brain injury or death,” said James P. Rathmell, MD, Anesthesiology editor-in-chief and author of the editorial, and professor of anesthesia at Harvard Medical School. “Narcan could be given almost any time, [and] the person would regain consciousness without harm. On the other hand, if the overdose is extreme or if the individual has no tolerance, breathing may stop immediately as soon as the drug ...

More: EMT Revives Knicks Fan With Narcan as FDA Expands Access to the Medication. On June 16, the FDA further expanded access to this lifesaving medication with another intranasal naloxone product, Rextovy, to help reduce opioid-related deaths in the United States. “In the U.S.

TL;DR: “Our study shows that the current doses of naloxone may not be sufficient to reverse overdoses caused by newer synthetic opioids,” study lead author Maarten A.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Bbc Jun 23, 16:30

Is vaginal microbiome testing worth it?

Testing the vagina microbiome is increasing in popularity with companies offering at-home tests

TL;DR: Testing the vagina microbiome is increasing in popularity with companies offering at-home tests

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 23, 15:16

A Small Lump in Her Neck Led to 2 Rare Tumors and a 24-Hour Surgery

Jayme Cohen Lynde’s rare tumor diagnosis led to a major surgery and a long recovery. Now, she is a thriving mom of two daughters. Image Credit: Photos by Jayme Cohen Lynde/Collage by Andrew Nguyen A lump in Jayme Cohen Lynde’s neck led to a carotid body tumor diagnosis and a second rare tumor called a paraganglioma. Surgery to remove the paraganglioma lasted 24 hours and required months of recovery, including relearning how to speak and swallow. Years later, doctors discovered a recurring tumor and a new tumor during routine follow-up care. After seeking a second opinion, Cohen Lynde and her doctor opted to monitor the recurring tumor rather than pursue radiation treatment. In 2000, Jayme Cohen Lynde was finishing her junior year at Michigan State University when she noticed a lump on the side of her neck. While she was largely symptom-free, she followed up with a specialist and learned she had a carotid body tumor, a rare growth that develops near the carotid arteries in the neck. Because the tumor was benign (noncancerous), her doctors told her she could finish the school year and spend the summer in New York for an internship. When she returned home in August, she expected to undergo a relatively minor surgery with a short recovery. Instead, the specialist who treated her wasn’t convinced they had the full picture. “The weekend before the surgery, [the specialist] had me do all these extra tests,” she told Healthline. “What we found out was, not only was there a carotid tumor living on my carotid artery, but there was a paraganglioma tumor that was living on the base of my skull.” Paragangliomas are rare neuroendocrine tumors that can develop in various parts of the body, including along cranial nerves. Because the paraganglioma appeared to be growing slowly, doctors decided to remove the carotid body tumor as planned first and allow Cohen Lynde to complete her senior year of college before addressing the second tumor. “It was an 8-hour surgery, and it took me [about] a week to recover,” she said. Cohen Lynde returned to school, completed her senior year, and began preparing to move to New York City for a job in advertising. A follow-up MRI with contrast, however, revealed that the paraganglioma was affecting blood flow to her brain. Doctors believed she needed another surgery before moving forward with her plans. Surgery hindered her ability to speak, swallow When she met with her doctor, he outlined two possible approaches. He explained that one option would be to operate directly through her skull. However, the risks included stroke, long-term complications, and even death. The second option involved assembling a team of specialists, including a second ENT and a plastic surgeon, to access the tumor through her mouth. The surgery would require removing a tooth, breaking her jaw, and opening part of her face to reach the tumor. The tradeoff was that she would need a feeding tube and a tracheostomy . She also wouldn’t be able to speak because the surgery would affect her vagus nerve . However, her doctor believed she would eventually recover, even if he couldn’t predict exactly how long it would take. Cohen Lynde chose the second option. What was expected to be a 12-hour surgery ultimately lasted 24 hours. However, doctors were able to remove the entire tumor. Photos by Jayme Cohen Lynde/Collage by Andrew Nguyen Recovery became her full-time job When she woke up after surgery, Cohen Lynde couldn’t talk. She had a feeding tube in her nose and couldn’t perform many basic tasks independently. “Even two weeks later, when I was home, my mom had to get in the shower with me,” she said. Recovery became her full-time job. Cohen Lynde couldn’t speak for around 10 months, and her feeding tube was eventually moved from her nose to her stomach. Once she had healed enough, she began working with an ENT specializing in the vocal cords. He developed an implant for her right vocal cord, and she worked with a speech therapist several times a week as she relearned how to speak, swallow, and eat. “I made my parents take pictures of me. They weren’t happy about that. But I had them take pictures once a week, because I wanted to see that I was recovering. I wanted to see the swelling going down, and I needed to see somehow that I was healing,” Cohen Lynde said. Though swallowing remains difficult for her today, she made it through the long recovery by focusing on her goal of moving to New York and building a career in advertising — a goal she ultimately achieved. Photos by Jayme Cohen Lynde/Collage by Andrew Nguyen Recurrence brought new challenges and a second opinion While Cohen Lynde built her career in advertising and became a mom to two daughters, she continued to receive annual checkups. A lthough her surgeries had been successful, she still required ongoing monitoring to watch for tumor recurrence. Years later, during a telehealth appointment, Cohen Lynde learned that one of her tumors had recurred and that she had...

More: “The weekend before the surgery, [the specialist] had me do all these extra tests,” she told Healthline. A follow-up MRI with contrast, however, revealed that the paraganglioma was affecting blood flow to her brain. However, the risks included stroke, long-term complications, and even death.

TL;DR: Jayme Cohen Lynde’s rare tumor diagnosis led to a major surgery and a long recovery.

Read original at Healthline →

Further reading: EatRightPubMed NutritionWHO NutritionWikipedia

Healthline Jun 22, 17:57

Zepbound vs. Wegovy: Which GLP-1 Drug Is Best for Weight Loss?

Researchers say that GLP-1 drugs containing tirzepatide (Zepbound, Mounjaro) may lead to greater weight loss. Image Credit: Tatsiana Volkava/Getty Images A meta-analysis found that one type of GLP-1 medication may be more effective than others. The analysis showed that GLP-1s containing tirzepatide (Zepbound, Mounjaro) helped people lose more weight than those containing semaglutide (Ozempic, Wegovy). Liraglutide (Saxenda) had the lowest weight loss percentage among users. The success of tirzepatide may be due to its dual mechanism, which targets multiple receptors. As around 2 in 5 U.S. adults meet the criteria for obesity, GLP-1 drugs have exploded in popularity as a weight loss aid. This blockbuster class of medications includes semaglutide ( Ozempic , Wegovy ), tirzepatide ( Zepbound , Mounjaro ), and liraglutide ( Saxenda ). A recent meta-analysis found that one of these medications may promote weight loss more effectively than others. The findings indicate that GLP-1s containing tirzepatide yield greater weight loss than semaglutide or liraglutide. “We were interested in finding which drug gives the most weight loss and doesn’t have higher rates of side effects like nausea and gastrointestinal problems,” Pooja Gokhale , corresponding author of the review and a doctoral student in the University of Georgia College of Pharmacy, said in a press release . “Tirzepatide seems to be the better option,” Gokhale said. Zepbound, Mounjaro yields greater weight loss The analysis found that those using tirzepatide (Zepbound or Mounjaro) lost 15–20% of their body weight. By comparison, participants taking semaglutide (Ozempic or Wegovy) lost around 12–13% of their body weight. Liraglutide (Saxenda) showed the lowest weight loss percentage, around 5%. GLP-1 medications work by mimicking natural hormones in the gut, which help to lower blood sugar, slow digestion, and promote feelings of fullness to aid weight loss. Semaglutide and liraglutide target GLP-1 receptors, whereas tirzepatide targets both GLP-1 receptors and another gut hormone, GIP. This dual mechanism may be what’s driving greater weight loss results with tirzepatide. The researchers also suggest that the way the body processes and interacts with the medication may play a role in weight loss. Liraglutide, in particular, has a half-life of only around 13 hours and requires a daily injection. Semaglutide and tirzepatide have half-lives of 1 week and 5 days, respectively, allowing weekly injections. “While tirzepatide may achieve greater average weight loss, there is no single ‘best’ medication for every patient,” said Clare Thompson , a general practitioner and weight management services lead at Cadogan Clinic in the United Kingdom. Thompson wasn’t involved in the study. “Future research will help us better understand whether the additional weight loss seen with tirzepatide translates into superior long-term health benefits compared with other GLP-1 therapies.” When to choose Ozempic, Wegovy instead While tirzepatide may lead to greater weight loss, a semaglutide medication may be more suitable for some people. Semaglutide is often less expensive than tirzepatide, which may be a deciding factor. “Semaglutide has been on the market for longer and subsequently has more robust, long-term data on outcomes for reducing heart attacks and strokes, and also good evidence to support a reduction in renal disease ,” said Thompson. Semaglutide is also available as an oral pill , which may help those who are averse to injections. Oral semaglutide ( Rybelsus ) was the first oral GLP-1 approved by the Food and Drug Administration (FDA). It was originally approved to treat type 2 diabetes, but may also aid weight loss. In December 2025, the FDA also approved an oral form of Wegovy specifically for weight loss. Despite the widespread success of GLP-1s for weight loss, experts encourage healthy lifestyle habits, such as a balanced diet and regular exercise. “Obesity should be viewed as a chronic medical condition requiring a personalized treatment approach — there isn’t a one-size-fits-all,” said Thompson. “The best outcomes occur when pharmacological treatment is combined with sustainable lifestyle changes, including improved nutrition, regular physical activity, adequate protein intake, and resistance training to help preserve muscle mass during weight loss.”

More: Wegovy: Which GLP-1 Drug Is Best for Weight Loss?. A recent meta-analysis found that one of these medications may promote weight loss more effectively than others. Thompson wasn’t involved in the study.

TL;DR: Researchers say that GLP-1 drugs containing tirzepatide (Zepbound, Mounjaro) may lead to greater weight loss.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Nutritionletter Jun 22, 02:56

Grilled Balsamic Chicken

Steps: 1. Combine all the ingredients, except the chicken, in large sealable plastic container or resealable plastic bag. Mix well. 2. Place the halved chicken breasts in the marinade for no less than 3 hours and up to 24 hours. 3. Preheat an outdoor grill to high. 4. Remove the chicken from the marinade, place […] The post Grilled Balsamic Chicken appeared first on Tufts Health & Nutrition Letter .

More: Combine all the ingredients, except the chicken, in large sealable plastic container or resealable plastic bag. Place the halved chicken breasts in the marinade for no less than 3 hours and up to 24 hours. Remove the chicken from the marinade, place […] The post Grilled Balsamic Chicken appeared first on Tufts Health & Nutrition Letter .

TL;DR: Remove the chicken from the marinade, place […] The post Grilled Balsamic Chicken appeared first on Tufts Health & Nutrition Letter .

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 21, 13:57

Want to Slow Your Aging? Multivitamins, Diet, and Fitness May Help

Studies show that diet, fitness, and multivitamins may help slow the aging process. Image Credit: Maria Sher/Stocksy Research suggests that taking a multivitamin every day may help slow the signs of biological aging. A recent study found that higher midlife cardiorespiratory fitness levels may be associated with a longer life span. According to new research, short-term dietary changes may help lower the gap between biological age and chronological age in older adults. Diet, lifestyle factors, and physical activity levels may help you live longer. Research suggests that a higher level of midlife cardiorespiratory fitness may help you live longer. Frequent aerobic exercise may also slow down the onset of numerous health conditions, such as heart disease, diabetes, and stroke. Another recent study found that daily multivitamins may help slow biological aging, the deterioration of the body at the cellular level. This compares with the body’s chronological age, the time that has passed since birth. Additionally, an article published in Aging Cell in April suggested that some short-term dietary changes may affect biological aging. Focusing on a diet rich in plant-based foods may be particularly beneficial. “Although everyone ages over time, there may be simple ways to delay the aging process and help us live not only longer but also better,” Sidong Li , MD, PhD, a postdoctoral researcher in the Division of Preventive Medicine at Brigham and Women’s Hospital, Boston, MA, told Healthline in a previous interview . Daily multivitamins help slow biological aging A 2026 study involving 958 older adults assessed the potential benefits of taking a multivitamin daily for 2 years. It used “epigenetic clocks” to measure biological aging after participants took Centrum Silver multivitamins and 500 milligrams (mg) of cocoa flavanols per day for 24 months. Epigenetic clocks are assessment tools that measure chemical changes to DNA. The study found that those who took the multivitamins experienced slightly slower biological aging than those in the placebo group. In a previous interview with Healthline, Michelle Routhenstein , preventive cardiology dietitian at Entirely Nourished, explained that “these are changes in biomarkers, not direct evidence of fewer heart attacks, cancers, or longer life span. So I would view the findings as encouraging but still preliminary.” Routhenstein wasn’t involved in this study. Higher midlife cardiorespiratory fitness promotes longevity Higher levels of midlife cardiorespiratory fitness in adults may help lengthen life span, according to a 2026 study . Cardiorespiratory fitness refers to the ability of the heart and lungs to deliver oxygen to the muscles during exercise or physical activity. The study assessed 24,576 adults ages 65 years or younger. Using the treadmill test, it was determined that men with a higher cardiorespiratory fitness had: 2% longer health span 9% fewer diseases 3% longer life span The study noted similar findings among women. “This study confirms our understanding of cardiorespiratory fitness as a marker of future health outcomes, and should encourage all of us to make physical activity a part of our daily lives,” explained Cheng-Han Chen , MD, board certified interventional cardiologist and medical director of the Structural Heart Program at MemorialCare Saddleback Medical Center in Laguna Hills, CA, in a previous interview with Healthline. Chen was not involved in the study. Short-term dietary changes may slow aging process A study published in April 2026 examined whether short-term dietary changes could affect estimates from the Klemera-Doubal Method (KDM) in older adults. KDM is an algorithm for assessing a person’s biological age. Biological age refers to aging at a cellular level. To assess whether diet could impact biological aging, participants adopted one of the following diets: omnivorous/high fat (OHF) omnivorous/high carbohydrate (OHC) semi-vegetarian/high fat (VHF) semi-vegetarian/high carbohydrate (VHC) The difference between participants’ KDM-determined age and their chronological age was calculated before the study and then again after 4 weeks. Participants following the OHF diet showed no known meaningful change. The study notes that this diet was most like the participants’ baseline diet. However, compared with those following the OHF diet, those following the OHC diet showed a significant reduction in the difference between their biological and chronological a ges . The VHC and VHF diets also led to similar reductions in the difference between the two ages. The study concludes that the biggest improvements occurred in diets rich in complex carbs and plant-based foods. “It doesn’t surprise me that this study showed that, in just four weeks, dietary changes that shift eating habits toward a more plant-forward pattern can have a meaningful impact on blood pressure , cholesterol, insulin sensitivity , and energy levels,” Routhenstein told Healthline. ...

More: Multivitamins, Diet, and Fitness May Help. Frequent aerobic exercise may also slow down the onset of numerous health conditions, such as heart disease, diabetes, and stroke. The study notes that this diet was most like the participants’ baseline diet.

TL;DR: Chen was not involved in the study.

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 20, 14:16

How This Mother-Daughter Duo Lost 163 Pounds With a Noninvasive Procedure

Molly Madore (left) and her mother, Diane Madore, underwent the same noninvasive weight loss procedure, losing a combined 163 pounds. Design by Healthline / Photo Courtesy of Diane and Molly A mother and daughter teamed up to undergo the same noninvasive weight loss procedure after years of difficulty with weight management. After Molly Madore’s success following an endoscopic sleeve gastroplasty (ESG), her mother, Diane Madore, underwent the same procedure, resulting in a combined 163-pound weight loss. The mother-daughter duo wants others to know about this noninvasive, non-medication weight loss strategy. Molly Madore and her mother, Diane Madore, navigated weight management for most of their lives. Molly, 34, said she can’t remember a time when managing her weight wasn’t a concern. “I’ve been overweight my whole life,” she told Healthline. “I’ve never had to chase a weight I once was because I’ve always been trying to lose weight.” As a teenager, she tried eating salads and making small changes. In her early 20s, she moved on to protein shakes , meal supplements, and other diets. However, no matter what she tried, she always fell into the same pattern. “As soon as I’d fail one meal, I felt like I failed the diet completely,” she said. “And then I’d be like, ‘Well, I’ll start Monday,’ and then Monday would roll around, and I just wouldn’t continue.” Then, in late 2023, she saw a Facebook advertisement for GLP-1 injections. She went to a local health facility and received a prescription. However, after experiencing GI side effects, she considered stopping the medication. Around the same time, while taking an elevator at the hospital where she works as a medical assistant, Molly saw a poster for endoscopic sleeve gastroplasty (ESG) , a minimally invasive weight loss procedure that reduces stomach volume by 70–80% to limit food intake. The procedure is done during an endoscopy that includes a flexible scope for the physician to place sutures inside the stomach, reducing its size to cause fullness without the need for cutting or incisions. The approach was appealing to Molly. Compared with GLP-1 medications , a nonsurgical ESG procedure may be more effective in the long term. “Medication effects typically wear off after they are stopped and can result in recurrent weight gain,” said Rabia De Latour , MD, associate professor at NYU Grossman School of Medicine. “By reducing the volume of the stomach with [an ESG], one creates restriction and promotes satiety, or fullness, with less food.” Molly decided to undergo the procedure, and the results were so successful that her mother, Diane, soon followed suit. Diane, 59, underwent the procedure in September 2025, aiming to reach her goal weight before her 60th birthday. Here, this mother-daughter duo shares their weight loss success stories after an ESG procedure. Turning to a noninvasive weight loss procedure People with obesity who have a body mass index (BMI) of 30–50 and an interest in nonsurgical, minimally invasive options are considered ideal candidates for ESG. In the summer of 2024, Molly moved forward with an ESG consultation and planned to schedule the procedure once she received insurance approval. “At that time, they weren’t quite sure that I’d even be approved, just because I didn’t have too many comorbidities,” she said. “And it was going to be the first time they were performing it at our facility; it was brand-new, first in the state, actually.” While she waited to hear back from her insurance company, Molly continued taking GLP-1 injections through October 2024. In early November, she got the OK to proceed with ESG, and her procedure was scheduled for December 2024. Despite waking up to a snowstorm on the day of her ESG, all went as planned for Molly, and she recovered quickly. She had the procedure on a Thursday and was back at work on Monday. “I wasn’t in pain by any means,” she said. “I just was mindful of what I had just gone through.” For the first week, she wore a heated vest to work for extra comfort and took prescribed medication to help manage stomach muscle spasms. The most common side effects from an ESG procedure are gastrointestinal symptoms, such as: nausea abdominal pain vomiting constipation burping diarrhea These symptoms typically resolve within 30–60 days. In addition to ESG, other available options for stomach volume reduction and satiety promotion via restriction include: laparoscopic sleeve gastrectomy (LSG) Roux-en-Y gastric bypass gastric bands (used less often) GLP-1 drugs prescribed for weight loss “[Choosing a method] is a personal decision and should be made through counseling with your clinician to allow you to make the right decision for you based on your health, your priorities, availability of procedure, recovery expectations, and comfort with the intervention,” De Latour told Healthline. A daughter inspires her mother’s weight loss journey Since December 2024, Molly has lost 86 pounds and currently weighs 146 po...

More: “I’ve never had to chase a weight I once was because I’ve always been trying to lose weight.” As a teenager, she tried eating salads and making small changes. She went to a local health facility and received a prescription. Here, this mother-daughter duo shares their weight loss success stories after an ESG procedure.

TL;DR: Molly Madore (left) and her mother, Diane Madore, underwent the same noninvasive weight loss procedure, losing a combined 163 pounds.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 19, 09:55

What to Consider Before Taking Sunscreen Advice on Social Media

Misinformation about sunscreen on social media platforms like TikTok appears to attract more engagement, according to a new study. Image Credit: Photo by Westend61/GettyImages A new study found that TikTok videos promoting misinformation about sunscreen tend to receive higher engagement. However, while some videos containing sunscreen misinformation garner more attention, a majority of sunscreen content on the platform is positive.  Experts warn that even a small amount of misinformation can have serious consequences if it discourages people from using sunscreen. A new study suggests that misinformation about sunscreen on TikTok may receive disproportionate engagement, representing a small fraction of the platform’s sunscreen-related content, which is mostly positive. The findings, published June 18 in PLOS Digital Health , were based on an analysis of 971 TikTok videos. Researchers found that most videos promoted sunscreen use , while only 16 videos discouraged it or questioned its safety. However, posts containing sunscreen misinformation tended to generate higher engagement rates. “Social media tends to reward content that is provocative or challenges accepted advice, so claims that sunscreen is harmful or unnecessary are often going to generate more discussion than straightforward health messaging,” said Paul Banwell , a plastic and cosmetic surgeon and skin health expert in the United Kingdom who wasn’t involved in the study. Even so, Banwell noted that even a relatively small amount of misleading content can sometimes attract outsized attention online, allowing myths about sunscreen to thrive. A spokesperson for TikTok told Healthline that the platform prohibits health-related misinformation, including inaccurate medical advice that discourages people from seeking appropriate medical care. Healthline spoke with Banwell about how to separate fact from fiction when viewing sunscreen content on social media and why sun protection is your best defense against skin cancer. This interview has been lightly edited for clarity and length. Why is sunscreen misinformation concerning? Banwell: The issue is that people can start to mistake popularity for credibility. Just because a video has millions of views doesn’t mean the information is accurate, and when it comes to sun protection, that can have real consequences if people are discouraged from using sunscreen based on misinformation rather than evidence. How would you like to see sunscreen content on social media change? Banwell:  A lot of sunscreen content focuses on preventing wrinkles, pigmentation, and premature aging , which are all valid benefits, but they shouldn’t be the whole conversation. As a doctor, my primary concern is skin health. Skin cancer is one of the most common cancers worldwide, yet it seems to feature far less prominently in online discussions than beauty-related benefits. Ideally, we should be talking about both. Many people, particularly younger audiences, get significant health information from social media. Influencers have a real opportunity to encourage positive habits, but with that comes responsibility. If sunscreen is only framed as an anti-aging product, people may decide it isn’t relevant to them. Understanding that it also helps protect against long-term UV damage and reduces skin cancer risk gives people a much stronger reason to make it part of their daily routine. Choosing the best sunscreen Sunscreen: Does SPF Matter and Which One Should I Choose? Find Your Sunscreen Soulmate: 15 Options Based on Skin Types 17 Best Face Sunscreens Our Favorite Sunscreens for Sensitive Skin, Dermatologist Approved What Sunscreen Ingredients to Look for — and Which Banned Ones to Avoid What do you wish more people knew about sun safety? Banwell: The habits we develop when we’re young often stay with us throughout adulthood. We also know that sun damage accumulates over time, and childhood sunburns can increase the risk of skin cancer later in life. The earlier we can educate children and teenagers about sun safety, the better. Ideally, wearing sunscreen should become as routine as brushing your teeth. This recent news is a reminder that healthcare professionals, brands, and creators all have an important role to play in making accurate information accessible and engaging. Sunscreen isn’t about avoiding the outdoors or living in fear of the sun. It’s about enjoying the sun sensibly while protecting your skin for the long term.

More: Misinformation about sunscreen on social media platforms like TikTok appears to attract more engagement, according to a new study. Image Credit: Photo by Westend61/GettyImages A new study found that TikTok videos promoting misinformation about sunscreen tend to receive higher engagement.

TL;DR: As a doctor, my primary concern is skin health.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Sciencedaily Jun 19, 03:17

Intermittent fasting triggers surprising changes in the brain

Losing weight may involve rewiring the gut and the brain at the same time. In a study of obese adults, an intermittent fasting-style diet led to significant weight loss, healthier metabolic markers, and notable shifts in gut bacteria. Brain scans also revealed changes in regions tied to appetite, cravings, and self-control. The results suggest the gut microbiome and brain may work together to influence weight-loss success.

More: Intermittent fasting triggers surprising changes in the brain. In a study of obese adults, an intermittent fasting-style diet led to significant weight loss, healthier metabolic markers, and notable shifts in gut bacteria. The results suggest the gut microbiome and brain may work together to influence weight-loss success.

TL;DR: Losing weight may involve rewiring the gut and the brain at the same time.

Read original at Sciencedaily →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 18, 16:21

GLP-1s Like Ozempic, Wegovy Linked to Surprising Drop in Violent Behavior

GLP-1s may help reduce impulsivity, alcohol intake, and violent behaviors in adults. Image Credit: munro/gettyimages A recent study found that GLP-1 medications like Ozempic and Wegovy may help lower impulsive and violent behaviors. The researchers noted that higher impulsivity and alcohol use were significantly associated with violent behavior overall, but were weaker among those using GLP-1s.  The findings suggest additional mental health benefits of GLP-1 drugs beyond alcohol use and addiction. GLP-1 medications have been shown to have many benefits in treating obesity and type 2 diabetes. This class of drugs has also been found to lower the risk of cardiovascular disease and certain cancers . There are psychological benefits as well, such as reduced “ food noise ” and cravings for alcohol and other substances . Now, a new study found that GLP-1 drugs like Ozempic and Wegovy may also help reduce violent behavior among adults.  The researchers found that higher levels of alcohol use and impulsivity were associated with violent behavior overall. However, the behaviors were weaker among GLP-1 users. The results were published on June 17 in Criminology . Lead study author Daniel Semenza , PhD, director of research at the New Jersey Gun Violence Research Center and an associate professor at Rutgers University, explained that the study was not designed to identify the biological mechanisms driving the relationship between GLP-1 use and violent behavior. “We can’t say with certainty why these associations emerged in this paper,” Semenza told Healthline. “However, growing research suggests that GLP-1 medications may influence things like reward processing and impulse control. One interpretation is that GLP-1 medications may weaken the extent to which established risk factors like impulsivity translate into harmful behavior. However, this is a hypothesis that requires further investigation,” he said. GLP-1s may reduce impulsivity, violent behaviors The researchers analyzed data from a 2025 survey of 7,521 adults in the United States. Their primary focus, however, was on the 821 individuals who had ever used a GLP-1 drug.  The researchers compared current GLP-1 medication users with former users. They examined whether using the medications changed the relationship between impulsivity , violent behavior, and alcohol use. Violent behaviors were measured using a validated self-reporting offending scale that assessed behaviors, such as: assault fighting robbery The researchers found that the association between impulsivity and violent behavior was about 62% weaker among current GLP-1 medication users compared with former users of the medications. “The strongest signal was the interaction between GLP-1 use and impulsivity, suggesting that the usual association between impulsivity and violent behavior was substantially attenuated among current GLP-1 users,” said Betul Hatipoglu , MD, professor of Medicine, CWRU School of Medicine. Hatipoglu wasn’t involved in the study.  “This study is interesting because it does not show that GLP-1 receptor agonists directly reduce violent crime. Rather, it suggests that among people taking GLP-1 medications, two well-established risk factors for violence — impulsivity and alcohol use — appear to have a weaker relationship with violent behavior,” she told Healthline. How GLP-1s may affect mental health Recent evidence suggests that GLP-1 medications may help reduce the desire for alcohol, especially in those with alcohol use disorder . But experts say the effects of GLP-1s on mental health are nuanced. “We’re seeing early evidence that GLP-1s may reduce cravings not just for food, but for alcohol and other substances, which has significant implications for addiction treatment,” Matt Glowiak , PhD, chief addiction specialist at Recovered, told Healthline. Glowiak wasn’t involved in the study. “At the same time… some individuals report improved well-being or reduced ‘mental noise’ around cravings, while others may struggle with identity shifts, restrictive patterns, or unrealistic expectations,” Glowiak told Healthline. “Clinically, I think of these medications as potentially powerful adjuncts but not replacements for therapy, behavioral change, or deeper work around coping and meaning,” he said. Semenza cited other recent studies that have examined the link between GLP-1 use and behavioral changes, including: cravings substance use reward-seeking behavior some aspects of impulse control “There is also growing interest in potential effects on mood and stress responses,” Semenza continued. “At the same time, it’s important to note that this is an evolving area of research. Some findings are stronger and more consistent than others, and we are still learning which effects are robust and what biological mechanisms may be involved.”  Semenza added that the current study should be viewed as a first step rather than a definitive answer.  “We found that the relationships between impulsiv...

More: GLP-1 medications have been shown to have many benefits in treating obesity and type 2 diabetes. How GLP-1s may affect mental health Recent evidence suggests that GLP-1 medications may help reduce the desire for alcohol, especially in those with alcohol use disorder . But experts say the effects of GLP-1s on mental health are nuanced. Glowiak wasn’t involved in the study.

TL;DR: This class of drugs has also been found to lower the risk of cardiovascular disease and certain cancers .

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 18, 11:24

Yes, Stair Climbing, Housework Count as Exercise. They Can Even Boost Your Mood

Small amounts of physical activity, like everyday chores, can boost your mood and even count toward your exercise goals. Image Credit: Getty Images/Oleh_Slobodeniuk New research has found that as little as 5 to 10 minutes of physical activity can provide an immediate boost to both mood and energy. Exercise and everyday movement are associated with meaningful improvements in emotional health. Even small bursts of physical activity can help you meet your fitness goals. Exercise provides various benefits for physical and mental health — even in small amounts. A large-scale study found that even 5 to 10 minutes of physical activity can improve energy levels and mood.  The findings, recently published in   Nature Human Behavior , emphasize the value of light-intensity movement. Everyday activities, such as household chores, taking the stairs, or going for a short walk, can have immediate positive effects on well-being. The researchers identified a bidirectional connection between movement and mood. Translation: Movement boosts your mood, which in turn, only makes you want to move more.  “There is a wealth of research supporting the connection between movement and an enhanced mood, partially through the release of endorphins and dopamine. Those same neurotransmitters directly increase motivation and drive, thereby making us more willing to be physically active,” Dara Houp , PsyD, licensed clinical psychologist with Pathways Psychological Services, told Healthline. Houp wasn’t involved in the study. Role of physical activity on mood The study was one of the largest real-world behavioral tracking initiatives. The researchers analyzed 8,000 international participants and over 320,000 individual mood ratings spanning 67 distinct datasets. Traditional clinical definitions in the past have limited exercise to high intensity gym workouts. However, the authors of this study used fitness-tracking wearables to measure spontaneous everyday movements.  This allowed researchers to consider the biological impact of light– and moderate–intensity movements, such as walking, climbing stairs, and doing routine household chores. They found that everyday activities like these had a significant impact on emotional health. The findings suggest that you don’t always need structured, intense fitness sessions to experience the psychological benefits of exercise. Simply exceeding your personal baseline of movement triggers immediate mood- and energy–boosting benefits.  “As a practicing physician, I see every day how closely mental well-being is tied to overall health,” said Bert Mandelbaum , MD, sports medicine specialist, orthopedic surgeon, and co-director of the Regenerative Orthobiologic Center at Cedars-Sinai Orthopedics in Los Angeles. Mandelbaum wasn’t involved in the study.  “Mental well-being isn’t just the absence of illness — it’s a state of emotional, psychological, and social balance that helps us manage stress, stay resilient, and engage meaningfully with the world around us,” he told Healthline. “ Research continues to show that exercise, especially outdoors, has measurable mental health benefits. Time spent in green spaces, whether it’s a park, trail, or even a neighborhood garden, has been linked to lower cortisol, reduced blood pressure, and improved mood,” he said. Tips to fit more movement into your day Getting more movement into your day doesn’t have to involve a grueling gym workout. Experts recommend starting small and keeping it simple. Whether it’s a 10-minute walk, cleaning your floors, or taking the stairs, there are myriad ways to add more movement into your day. “Find something you actually enjoy and make it fit into your life,” said Houp.  “In many circumstances, action (working out) comes before motivation (the desire to work out). Making the action step small (i.e., 15 jumping jacks) increases the likelihood of achieving it and, upon success, your body provides itself with a reward (dopamine), thereby reinforcing the likelihood you will take an additional action step (i.e., 10 minutes of walking), she added. Houp described the process of starting with small actions that build with motivation as a “snowball effect.” She offered the following tips for getting started: If you’re not a runner, walk. If you can’t afford a gym membership, try a YouTube workout. If you don’t have time, “habit stack” by doing squats while brushing your teeth. If you’re worried about your ability to commit, find someone to help hold you accountable. “There will always be an excuse. Don’t wait for the motivation, time, or energy. Start small and start now,” she said.  Mandelbaum suggested adding an element of adventure to enhance the physical and mental health benefits. “Adventure doesn’t have to mean extreme activities, it can be as simple as trying a new hiking trail, taking a beginner fitness class, kayaking, or exploring a new neighborhood,” he said. “These experiences encourage mindfulness, helping people stay present rather...

More: Exercise provides various benefits for physical and mental health — even in small amounts. Houp wasn’t involved in the study. “ Research continues to show that exercise, especially outdoors, has measurable mental health benefits.

TL;DR: Exercise and everyday movement are associated with meaningful improvements in emotional health.

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 17, 17:48

Setting a Goal Weight May Lead to Greater Success With GLP-1s Like Zepbound

Setting a weight loss goal may yield greater success with GLP-1 drugs like Zepbound. Image Credit: Crispin la valiente/GettyImages A recent study found that people who set personal weight loss targets may achieve greater results with GLP-1 medications.  People using tirzepatide (Zepbound or Mounjaro) saw more weight loss if they set goals or had previously tried structured diet plans.  The results also indicate that women tended to experience greater weight loss with GLP-1s than men, suggesting sex-specific differences. Millions of people have achieved significant weight loss with GLP-1 medications, a blockbuster class of drugs that mimic an appetite-suppressing hormone to trigger significant metabolic changes. Some people may experience more weight loss than others while using these medications, but there are various strategies that can help promote long-term weight loss.  New research examined weight loss outcomes among people using tirzepatide ( Zepbound and Mounjaro ). The study included people who set personal weight loss goals and those without pre-existing conditions, such as type 2 diabetes.  The findings show that females lost more weight than males, and those who set personal weight loss goals experienced greater weight loss. The results have not yet been published in a peer-reviewed journal but were presented at ENDO 2026 , held from June 13–16 in Chicago, IL. “These findings align with my own clinical experience. I have found that patients who set realistic goals and actively work toward them through dietary and lifestyle changes are more likely to see significant benefits from weight loss medications,” said Mir Ali , MD, medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA. Ali wasn’t involved in the study.  Goal setting yields greater weight loss with GLP-1s The study analyzed data from 80,942 individuals with an average age of 43 who had just begun treatment with a GLP-1 drug containing the active ingredient tirzepatide. Of these, 21,490 reached the 6-month follow-up. At the 12-month follow-up, 4,429 participants were included. The majority of the participants were still accruing follow-up time.  The researchers found that females were significantly more likely than males to achieve a 20% total body weight loss by the 12-month follow-up. They also found that individuals who set a baseline weight loss goal and had previously attempted diet plans achieved a higher percentage of weight loss. The findings suggest that setting a weight loss goal while using a GLP-1 medication may lead to even greater weight loss.  “This isn’t surprising, given that psychological research has shown that setting goals provides direction, can help focus attention, and can help us maintain commitment and motivation to our goals,” said Nicole Andreoli , PhD, licensed psychologist with Pathway Psychological Services in New York, NY. Andreoli wasn’t involved in the study. “While the GLP-1 medications can help with the biological aspects of appetite and food noise, goal setting helps with the behavioral pieces, such as monitoring progress, making intentional choices, and maintaining consistency,” she told Healthline. Additionally, those with pre-existing conditions at the start of the study were less likely to achieve the 20% body weight loss target by the 12-month follow-up. These conditions included:  type 2 diabetes high cholesterol high blood pressure (hypertension) metabolically-dysfunctional-associated liver disease (MASLD) obstructive sleep apnea “These findings could help physicians better counsel patients about realistic expectations and tailor their support to the needs of each patient,” study author Hans Johnson , research lead in the Department of Clinical Research and Innovation at Voy, said in a press release . “For example, doctors could ensure patients with motivational barriers to losing weight receive additional behavioral interventions alongside their medication,” Johnson continued. Other tips for losing weight with GLP-1 drugs GLP-1 drugs promote weight loss, but many people may experience weight regain when they stop taking the medication. For long-term weight management, experts emphasize adopting healthy lifestyle habits. Pairing GLP-1 drugs with practical goal-setting and sustainable behavior change is key to success. “Regardless of whether a patient is using medication, has undergone weight loss surgery, or is seeking dietary advice, I emphasize that the most effective approach is to reduce carbohydrate and sugar intake while prioritizing proteins and vegetables. This approach encourages the body to burn fat stores,” Ali told Healthline. “Additionally, I recommend regular exercise — even walking — to help minimize muscle loss during the weight loss process,” he said. Andreoli noted that “food awareness” is important. “I always stress to my clients: pay attention to your relationship with food,” she said. “GLP-1 medications create a ...

More: Setting a Goal Weight May Lead to Greater Success With GLP-1s Like Zepbound. Andreoli wasn’t involved in the study. “GLP-1 medications create a ...

TL;DR: Other tips for losing weight with GLP-1 drugs GLP-1 drugs promote weight loss, but many people may experience weight regain when they stop taking the medication.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jun 17, 15:42

Mayim Bialik's GLP-1 Experience Left Her With ‘Uncontrollable’ GI Symptoms

Mayim Bialik recently shared the “nightmare” experience she had after using a GLP-1 drug. Image Credit: Laurent Koffel/Getty Images Actor Mayim Bialik has shared her “nightmare” experience that left her with weeks of side effects after one GLP-1 medication dose. Bialik said her symptoms included severe diarrhea and full-body aches.  She revealed that she tried a GLP-1 after her doctor suggested it may help with her autoimmune disease symptoms. Emmy Award-winning actor Mayim Bialik, of “Blossom” and “Big Bang Theory” fame, opened up about her experience with a GLP-1 medication.  In an essay for The Free Press , Bialik wrote, “To say I had an adverse reaction would be somewhat of an understatement.” After one low dose injection of the GLP-1 medication , she said she began to experience gastrointestinal symptoms that left her unwell for weeks.  When Bialik visited a gastroenterologist about her symptoms, she was told that dramatic side effects from GLP-1 drugs can be quite common. The doctor also informed Bialik that the other medications she was taking may have contributed to her symptoms.  Here’s why Bialik turned to GLP-1s and why her autoimmune disease symptoms may have exacerbated her side effects. Bialik’s GLP-1 experience was a ‘nightmare’  Bialik shared that she had gained around 20 pounds during early menopause . However, that wasn’t why she started using a GLP-1 medication. She had been told that the medication may help ease some of the symptoms she had lived with most of her adult life.  She was diagnosed with Graves’ disease , an autoimmune condition, when she was 23. At 48, Bialik consulted with various specialists for other symptoms she was experiencing after perimenopause . Each physician gave her a separate autoimmune diagnosis, but none seemed 100% certain. She decided to try a GLP-1, not for her postmenopause weight gain, but because three separate doctors suggested she try it to help with her autoimmune symptoms. There is evidence to show GLP-1s may help reduce inflammation. “There have been studies showing GLP-1 medications improving cardiovascular health , cognitive health , [and] kidney function , to name a few,” Mir Ali , MD, medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, told Healthline in a previous interview . However, after one dose of the GLP-1 medication, Bialik began to experience severe side effects. She wrote in her essay that she experienced “explosive, uncontrollable diarrhea. Sulfur burps so violent, they left me afraid to open my mouth in public. Sneezing attacks every time I tried to eat or drink—which apparently has a name: snatiation .” “Cramping. Bloating. Full-body aching, as though I had the flu,” she said. “And an inability to keep down even small sips of water without sprinting to the bathroom with yet more explosive diarrhea. More than three times, I didn’t make it.” Jeffrey Lee , MD, a double board certified plastic surgeon and founder of JL Plastic Surgery in Boston, MA, told Healthline in a previous interview that gastrointestinal side effects from GLP-1s are not unusual. “The most common side effects I see in practice are gastrointestinal, things like nausea, bloating, or constipation,” Lee said. Bialik said that although her GLP-1 experience was a “nightmare,” it shouldn’t overshadow the widespread success that millions of people have had with this class of drugs. “GLP-1s have helped people in serious need,” Bialik said. “Of that I am certain. But nobody talks much about what happens when it goes wrong.”

More: She decided to try a GLP-1, not for her postmenopause weight gain, but because three separate doctors suggested she try it to help with her autoimmune symptoms. “There have been studies showing GLP-1 medications improving cardiovascular health , cognitive health , [and] kidney function , to name a few,” Mir Ali , MD, medical director of MemorialCare Surgical Weight Loss Center…

TL;DR: Mayim Bialik recently shared the “nightmare” experience she had after using a GLP-1 drug.

Read original at Healthline →

Further reading: EatRightWHO NutritionNutrition.govWikipedia

Healthline Jun 16, 18:29

FDA Clears First Over-the-Counter Continuous Glucose Monitor for Kids

The FDA approved the first nonprescription sale of Dexcom’s continuous glucose monitor for children ages 2 to 18 with diabetes. Svetikd/Getty Images The Food and Drug Administration (FDA) approved the first over-the-counter continuous glucose monitor for children under 18. Experts say the over-the-counter version will make this helpful technology more widely available to families who need diabetes care. The devices could help parents and children make healthy lifestyle decisions, but the technology should still be used under a medical professional’s supervision. Federal regulators have authorized the first over-the-counter continuous glucose monitor (CGM) for children. Officials at the Food and Drug Administration (FDA)  approved  the nonprescription sale of the  Stelo Glucose Biosensor System  manufactured by Dexcom for children ages 2 to 18 years. The wearable device is designed for children, including those with diabetes, who receive oral medication to manage their condition. It is not intended for children who need insulin injections. The device can also be used by children and parents who want to understand how diet, exercise, and other lifestyle changes affect glucose levels. However, the FDA cautioned that the monitoring system is not intended for individuals with problematic hypoglycemia because it is not designed to alert users when low blood sugar occurs. It’s also not intended for people on dialysis. In addition, the FDA said individuals with eating disorders should consult their healthcare professional before use. Federal regulators added that children should use the glucose monitor only under an adult caregiver’s supervision. The FDA  approved  an over-the-counter version of the Stelo Glucose monitor for individuals 18 years and older in March 2024. Participants involved in previous research have reported mild side effects, including local infection, skin irritation, pain, and discomfort. The Stelo Glucose system uses a wearable sensor paired with a smartphone app to continuously measure, record, analyze, and display glucose levels. The app displays glucose measurements and trends every 15 minutes. Each sensor lasts for up to 15 days before it must be replaced. Regulatory officials said the new device will make it easier for parents and children to manage conditions such as diabetes. “Children deserve access to the best tools available to manage their health,” said  Michelle Tarver , MD, PhD, the director of the FDA’s Center for Devices and Radiological Health, in a statement .  “[The] clearance reflects the FDA’s commitment to fostering innovation for pediatric patients and supporting the safe and effective use of medical devices where children live, learn, and play,” Tarver continued. Benefits of continuous glucose monitors The first real-time continuous glucose monitor was released by Dexcom in 2006. There are four basic continuous glucose monitor systems approved for use in the United States. They are usually prescribed to individuals who have been diagnosed with diabetes. Researchers have stated that continuous glucose monitors have  revolutionized  diabetes care. They point to research that reports that continuous glucose monitor technology is beneficial for people with  type 1 diabetes  and  type 2 diabetes , as well as for individuals with  gestational diabetes  during pregnancy. A February 2025 study concluded that continuous glucose monitors have been beneficial in helping children manage type 1 diabetes. “[The glucose monitors] have been very helpful in managing diabetes,” said  Graham Tse , MD, a pediatrician and chief medical officer of MemorialCare Miller Children’s & Women’s Hospital in Long Beach, CA. Tse explained that the monitors provided a steady stream of information for parents monitoring their young children’s blood sugar levels , as well as for teens keeping track of their own levels. He said the data is more constant and less invasive than the occasional finger prick to draw blood for testing. Tse said parents and teens can make decisions about diet and exercise using the monitors, based on whether glucose levels are high or low at any given moment. “It allows them to make healthier choices,” he told Healthline. “Throughout the day, they can receive lots of data points.” Tse added that an over-the-counter option would make this technology more widely available. “It provides greater access to more of our community,” he noted. Daniel Ganjian , MD, a pediatrician at Providence Saint John’s Health Center in Santa Monica, CA, echoed these sentiments. “[Children] can learn how eating has an effect on their blood sugar,” he told Healthline. “It helps them make better decisions.” Marilyn Tan , MD, an endocrinologist and professor of medicine at Stanford University, said that continuous glucose monitors provide more convenient and more helpful information. “This [continuous glucose monitor] provides continuous glucose measurements every 15 minutes, which provides signific...

More: FDA Clears First Over-the-Counter Continuous Glucose Monitor for Kids. “Children deserve access to the best tools available to manage their health,” said  Michelle Tarver , MD, PhD, the director of the FDA’s Center for Devices and Radiological Health, in a statement .

TL;DR: “[Children] can learn how eating has an effect on their blood sugar,” he told Healthline.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 16, 15:20

Taking a GLP-1 Like Ozempic? These Health Risks Are Higher in the Heat

Using GLP-1s may increase your risk of heat-related illnesses. Image Credit: Nora Carol Photography/Getty Images GLP-1 medications may increase heat-related risks by suppressing thirst and reducing fluid intake. Thirst reduction may lead to severe dehydration and even kidney damage.  GLP-1 drugs may also lower blood pressure in some people, potentially leading to other heat-related issues in people with low blood pressure.  People using GLP-1s also need to properly store their medications, as heat can damage them.  Heat waves during the summer months are increasingly common. What does this mean for people using GLP-1 drugs like Ozempic , Wegovy , or Mounjaro ?  GLP-1 medications may increase the risk of dehydration, particularly in hotter weather. The Food and Drug Administration (FDA) warns that severe dehydration from GLP-1 drugs may raise the risk of kidney injury and damage.  Proper storage of these drugs is also important, as heat can damage the medication and render it ineffective. Clare Thompson , general practitioner and lead of the weight management services at Cadogan Clinic in the United Kingdom, advised extra precautions during hot weather for those taking GLP-1 drugs. Healthline spoke with Thompson about how taking GLP-1s may lead to dehydration and other heat-related illnesses, and how to properly store the medication during hot weather.  This interview has been lightly edited for length and clarity. Why do GLP-1s raise the risk of heat-related illness? Thompson: GLP-1 medications suppress your natural thirst cues , which means you naturally drink less fluid. They can also delay stomach emptying and cause nausea, which may result in drinking less fluid GLP-1 medications seem to lower blood pressure in some patients, which can also make patients susceptible to dizzy spells and fainting. This is further compounded by the heat, which can cause you to sweat more and lose further fluids. This slight lowering of blood pressure can sometimes be beneficial in people with hypertension . However, in patients with pre-existing n ormal to low blood pressure , special consideration must be taken to ensure their pressure doesn’t drop to dangerously low levels. Signs of dehydration Signs you may be dehydrated include: altered mental status or poor concentration fatigue low urine output darker-colored urine dry skin and cracked lips decreased skin elasticity headaches dizziness or lightheadedness heart palpitations low blood pressure How can people taking GLP-1 drugs stay hydrated? Thompson: There are simple steps patients can take to mitigate dehydration while taking GLP-1 medications during a heatwave. Drink electrolytes instead of plain water to replenish the sugar and salts needed to maintain hydration and bodily functions. Aim for 1.5–2 L of fluids per day and set a reminder on their phone to prompt them to drink. The heat itself also suppresses appetite, so having smaller, protein-rich foods can help stabilize blood sugar and prevent the effects of low blood glucose and feeling faint. Cutting back on alcohol and caffeinated drinks, which are diuretics and cause further fluid loss, can also help prevent dehydration. Signs of heat-related illness Signs of heat exhaustion can include: drop in blood pressure when exerting yourself dizziness nausea feeling faint sweating profusely moist, cool, or cold skin weak and rapid pulse headache muscle cramps The more severe condition, heatstroke , is a medical emergency. Signs include: running a high fever, skin hot to the touch excessive sweating or dry skin that doesn’t sweat muscle cramps rapid pulse or heart rate low blood pressure disorientation irrational or erratic behavior dizziness headache nausea or vomiting dry mouth and intense thirst physical collapse coma How should GLP-1 medications be stored during hot weather?  Thompson: Extreme heat can also damage the medication and alter the properties of the proteins. To protect the medication, store it away from direct sunlight. Ideally, it should be in the fridge at 2–5°C (35.6F–41F) before opening, or at room temperature once used.  GLP-1 medications should not go above 30°C (86F).  Use an insulating pouch or cool bag when traveling with the pen to prevent extreme temperature changes that could damage the medication.

More: Taking a GLP-1 Like Ozempic? These Health Risks Are Higher in the Heat. What does this mean for people using GLP-1 drugs like Ozempic , Wegovy , or Mounjaro ?  GLP-1 medications may increase the risk of dehydration, particularly in hotter weather.

TL;DR: Using GLP-1s may increase your risk of heat-related illnesses.

Read original at Healthline →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 15, 13:46

How Ultra-Processed Foods Are Made Matters as Much as What's in Them

The manufacturing processes used to produce ultra-processed foods are linked to negative impacts on human health. Image Credit: Andy Sacks/Getty Images A recent study has found that it may not just be what’s in ultra-processed foods that makes them unhealthy, but how they’re made. The study noted that factors such as changes in the food’s cellular structure, loss of beneficial chemical compounds, and additives and chemicals in packaging may all pose health risks. This adds to previous research that shows that ultra-processed foods can negatively affect health. Public concern over the effects of ultra-processed foods has been growing. Research has increasingly associated these foods with a higher risk of conditions like heart disease , diabetes , obesity , and even early death . Despite these concerns, ultra-processed foods make up around 55% of the American diet. “UPFs [ultra-processed foods] do offer some advantages, but at the expense of the consumer’s health. They are convenient, affordable, have a long shelf life, and are often engineered to be highly palatable, which contributes to their widespread consumption,” said Mir Ali , MD, medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA. Ali was not involved in the study. “Because of these factors, UPFs are extremely prevalent in the modern diet. While many people are generally aware that these foods are not optimal for health, convenience and taste often drive decision making,” he told Healthline. Experts are also still looking into exactly what drives the risks from ultra-processed foods. They are debating whether it is the nutritional quality of the foods, as they are often high in sodium, added sugars, and refined grains, or if it is the industrial processing and additives used to make them. A recent study published in the American Journal of Public Health (AJPH) suggests that processing may actually play an independent role in the health risks posed by ultra-processed foods. The researchers found that people who ate more ultra-processed foods had worse health outcomes. This was evident even after accounting for the overall nutritional values of the foods. How are ultra-processed foods made? The study used data from the National Health and Nutrition Examination Survey (NHANES) to investigate the relationship of ultra-processed foods with cardiometabolic risk factors, prevalent disease conditions, and all-cause mortality. The researchers evaluated the associations both with and without adjusting for the nutritional quality of the ultra-processed foods. The research team used a standard classification system to group foods according to how they were prepared. These groups ranged from minimally processed foods like fruits and vegetables to ultra-processed foods, which are made with industrial ingredients and additives that are not typically used in cooking.  They also rated the nutritional quality of foods by scoring them based on their overall healthfulness. Each participant also received an overall diet quality score based on the foods they reported eating. The researchers examined how the consumption of ultra-processed foods was linked to current health measures, such as blood sugar, weight, and cholesterol, as well as long-term risk of death. The study showed that for every 10% increase in calories from ultra-processed foods, individuals had worse health markers. Those who ate larger amounts of ultra-processed foods tended to have: higher body weight lower blood sugar management higher blood pressure worse cholesterol levels These individuals were also more likely to have conditions, such as diabetes , metabolic syndrome , and cancer . They also had a higher risk of dying during the study period. These connections remained even after accounting for the food’s nutrient quality, as well as the amount of saturated fat , added sugars , and sodium in the ultra-processed foods. The patterns remained largely the same across subgroups of individuals. “Overall, these findings reinforce existing concerns about ultra-processed foods. While awareness of their risks is relatively high, making consistent, healthier choices can be difficult — particularly when cost, convenience, and availability are limiting factors,” said Ali. Health effects of ultra-processed foods Ultra-processed foods can contribute to the development of various health conditions. “Numerous health studies have linked ultra-processed foods to a wide range of problems, including diabetes, hypertension , obesity , and hyperlipidemia ,” said Cheng-Han Chen , MD, medical director of the Structural Heart Program at MemorialCare Saddleback Medical Center in Laguna Hills, CA. Chen wasn’t involved in the study.  “These conditions can lead to serious adverse health outcomes, as they are known to be risk factors for cardiovascular diseases such as heart attack and stroke . It is thought that ultra-processed foods affect car...

More: The researchers found that people who ate more ultra-processed foods had worse health outcomes. The researchers examined how the consumption of ultra-processed foods was linked to current health measures, such as blood sugar, weight, and cholesterol, as well as long-term risk of death. They also had a higher risk of dying during the study period.

TL;DR: Health effects of ultra-processed foods Ultra-processed foods can contribute to the development of various health conditions.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Bbc Jun 15, 05:08

'I won't have another baby after breastfeeding trauma'

New mothers say they did not receive enough breastfeeding support when their babies were born.

More: 'I won't have another baby after breastfeeding trauma'. New mothers say they did not receive enough breastfeeding support when their babies were born.

TL;DR: New mothers say they did not receive enough breastfeeding support when their babies were born.

Read original at Bbc →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Bbc Jun 14, 23:10

Why you might not be buying the right pain relief for period cramps

Many women are buying less effective pain medication for period cramps, supermarket data suggests.

More: Why you might not be buying the right pain relief for period cramps. Many women are buying less effective pain medication for period cramps, supermarket data suggests.

TL;DR: Many women are buying less effective pain medication for period cramps, supermarket data suggests.

Read original at Bbc →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 14, 08:35

FDA Approval of Inhaled Insulin Has Been Life-Changing for This Teen with Diabetes

Jennifer Seigrist (left) and her daughter Taisie Seigrist (right). Photo by Jennifer Seigrist The FDA has approved Afrezza, an inhaled insulin, for children and adolescents. Taisie Seigrist is a 15-year-old who took part in the clinical trial for Afrezza. Seigrist said the needle-free option has changed her life. When Taisie Seigrist was 10 years old, she began experiencing persistent thirst and the urge to urinate frequently. “She would come home from school and drink five glasses of water instantly,” her mom, Jennifer, told Healthline. Concerned that Taisie might be ill, Jennifer turned to her sister-in-law, who lives with type 2 diabetes , for help. Jennifer asked her if she could borrow her glucose meter to test Taisie’s blood sugar . The device revealed that Taisie’s blood sugar was 684 mg/dL, which is dangerously high. “We called our doctor, and he said go straight to the children’s hospital, so we did, and we were there for about a week,” said Jennifer. Doctors diagnosed Taisie with type 1 diabetes in 2021. “It was scary for both of us to hear,” said Jennifer. Learning to live with type 1 diabetes While Taisie left the hospital with a continuous glucose monitor that helped manage her condition, she also relied on mealtime injected insulin shots , as often as seven times per day. “A pump wasn’t really a good option for us because of our lifestyles,” said Jennifer. For the first two years after Taisie’s diagnosis, her mom administered mealtime shots for her. Then Taisie began doing them herself. Because Taisie didn’t have a lot of body fat, she had to keep returning to the same injection sites. “Taking shots really hurt, especially doing it in the same place,” Taisie told Healthline. The shots also affected her quality of life. Injected rapid-acting insulin takes about 15 minutes to start working and stays in the body for 2 to 3 hours, which made it difficult for Taisie to administer during school and at track and cross-country. If her blood sugar needed correcting right before a race, she’d have to sit out. “It kept her from being able to participate at certain times,” said Jennifer. Managing her condition took an emotional toll, too. In elementary school, her classmates accused her of taking insulin shots for attention, which made an already difficult condition feel even more isolating. Michael Glazier, MD, Chief Medical Officer at Bluebird Kids Health, said mealtime insulin is challenging for anyone living with diabetes, but especially for children and adolescents. Varying schedules, feelings of denial and rebellion, as well as the inconvenience, embarrassment, and stigma associated with injection administration in front of peers, can add to the difficulty and make adherence more challenging, he said. “It is unfortunately obviously easier to ‘skip’ a mealtime dose than to give one, and this inevitably leads to less time their blood sugars are in the desired range and more complications as they age,” Glazier told Healthline. Finding a new treatment in a clinical trial In 2024, during a routine appointment, Taisie’s endocrinologist asked whether she would be interested in participating in a clinical trial of Afrezza, an inhaled mealtime insulin taken before eating that mimics the body’s natural insulin response at mealtime. “We jumped at the chance,” Jennifer said. While Taisie didn’t fully understand the science of the trial, she was intrigued by a new treatment option. “Once I heard that it was inhalable insulin, I got really excited because I didn’t have to take shots,” she said. She responded well to the medication. Jennifer said it gives her metabolic flexibility. “With injections, she would take a shot 15 minutes before she would start eating and then it would stay in her system for two to three hours, so we couldn’t do a correction for two to three hours, whereas with the inhaled insulin, as soon as you take it, it’s in your system and out of your system in an hour so we start doing corrections if we need to a lot sooner which keeps her A1C down and her number down and it’s really amazing and it’s so easy.” For Taisie, the difference is something she can feel. “It’s made my blood [sugar] more level than it was when I was taking shots,” she said. She also feels social and emotional benefits. Before, the thought of eating cake at a birthday party meant mentally calculating another shot and deciding whether the food was worth it. Now, Taisie just eats. “She doesn’t have to be like, ‘No, I don’t want that because I don’t want to do another shot,’” Jennifer said. Today, Taisie only takes one shot of long-acting insulin at night. Afrezza is FDA approved On May 29, 2026, Afrezza became FDA-approved for children ages 6 and older living with type 1 and type 2 diabetes, about 12 years after the medication was approved for adults. Jennifer and Taisie hope the news will help others get access to the medication, as they currently pay out of pocket for it at a discounted rate for participating in the tria...

More: FDA Approval of Inhaled Insulin Has Been Life-Changing for This Teen with Diabetes. Concerned that Taisie might be ill, Jennifer turned to her sister-in-law, who lives with type 2 diabetes , for help.

TL;DR: “It’s made my blood [sugar] more level than it was when I was taking shots,” she said.

Read original at Healthline →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 13, 08:14

People Using GLP-1s, Like Ozempic, Wegovy, Less Likely to Exercise Despite Benefits

Recent research has found that despite the benefits, people using GLP-1s may be less likely to exercise. Image Credit: Fiordaliso/Getty Images A recent study found that people taking a GLP-1 medication, like Ozempic or Wegovy, may be less likely to engage in regular exercise. The study showed that, among people with obesity, daily step count and moderate-to-vigorous activity duration decreased after starting GLP-1 medication. The greatest decline was seen in males and people with musculoskeletal pain. GLP-1 medications, like Ozempic , Wegovy , and Mounjaro , have become popular ways for people to lose weight and manage conditions like diabetes. A recent study found that people who begin using a GLP-1 medication appear to engage in less physical activity. However, evidence suggests that long-term weight management is most effective when combined with regular exercise. “This study aligns with my clinical experience. I often find that patients feel more fatigued while losing weight, which can make exercise feel like a chore,” Mir Ali , MD, medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, told Healthline. Ali wasn’t involved in the study. This study is being presented at ENDO 2026 , the Endocrine Society’s annual meeting in Chicago, Illinois, and has not yet been published in a peer-reviewed journal. “While many assume that weight loss leads naturally to increased physical activity, our study suggests otherwise,” Sajana Maharjan , MD, board certified internist at HSHS St. John’s Hospital in Springfield, IL, and lead author of the study, said in a press release .  “The findings in our study reinforce that exercise cannot be optional for people taking these medications. People need targeted interventions that encourage physical activity alongside medication for obesity.” Why do people using GLP-1 medications exercise less?  The study used data from the National Institutes of Health (NIH) All of Us Research Program . The All of Us Research Program links health records with Fitbit activity data. This enabled the researchers to objectively assess physical activity patterns. The researchers identified the individuals from the research program with obesity who had initiated a GLP-1 medication and who had Fitbit activity for both before and after the treatment. They identified 753 people with sufficient Fitbit data. Of these, 78.6% were female, with an average age of 52.7. Common comorbid conditions included: type 2 diabetes hypertension (high blood pressure) musculoskeletal (MSK) pain The research team compared each participant’s physical activity before and after starting a GLP-1 medication. They specifically focused on daily step counts and moderate-to-vigorous physical activity (MVPA) minutes. The researchers found that, on average, daily step counts decreased from 5,047 to 4,487. The MVPA fell from 28 to 22 per day after beginning their GLP-1 medication. The largest decline was observed among males and among people with muscle or joint pain. Factors such as age, prior stroke, or heart failure did not appear to change the results. The study found no evidence that weight loss from GLP-1 medications was associated with increased physical activity. Why exercise is important when using a GLP-1 Ali said that a lack of exercise can “lead to increased muscle loss, heightened fatigue, and suboptimal weight loss results.” Prior research also shows that regular exercise helps maintain weight loss. It can also improve cardiorespiratory fitness, lower chronic disease risk, and enhance mental well-being. Side effects of GLP-1 medications, such as fatigue, can make it more difficult to get regular exercise. However, Ali noted that “consistency is more important than intensity.” “The goal is 30 minutes per day, five days a week; even walking provides significant benefits. This can be broken into smaller segments if 30 minutes at once is not feasible. Ideally, a combination of aerobic exercise and resistance training is best for preserving muscle,” Ali said. “While the majority of weight loss stems from dietary changes, physical activity remains essential for muscle preservation and overall health.”

More: Ali wasn’t involved in the study. The study found no evidence that weight loss from GLP-1 medications was associated with increased physical activity. “While the majority of weight loss stems from dietary changes, physical activity remains essential for muscle preservation and overall health.”

TL;DR: Recent research has found that despite the benefits, people using GLP-1s may be less likely to exercise.

Read original at Healthline →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Cnn Jun 13, 03:13

The benefits of 'body doubling' when you have ADHD, according to experts

'Body doubling' is a strategy people with ADHD can use to accomplish more than they would alone. Here's how to do it.

More: The benefits of 'body doubling' when you have ADHD, according to experts. 'Body doubling' is a strategy people with ADHD can use to accomplish more than they would alone. Here's how to do it.

TL;DR: 'Body doubling' is a strategy people with ADHD can use to accomplish more than they would alone.

Read original at Cnn →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Cnn Jun 13, 03:13

The planet is getting hotter fast. This is what happens to your body in extreme heat

Human-caused climate change has already made heat waves around the world more frequent and intense.

More: The planet is getting hotter fast. This is what happens to your body in extreme heat. Human-caused climate change has already made heat waves around the world more frequent and intense.

TL;DR: Human-caused climate change has already made heat waves around the world more frequent and intense.

Read original at Cnn →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 12, 17:00

‘Spermmaxxing’: Social Media Influencers are Monetizing Male Fertility Anxiety

“Spermmaxxing” is the newest social media trend. Why are younger males so concerned with fertility? Image Credit: Irina Shatilova/Getty Images “Spermmaxxing” is one of the most recent social media “maxxing” trends. In this trend, men seek to increase their fertility through lifestyle changes and other approaches, such as eating raw garlic. “Maxxing” refers to maximizing almost anything and has become part of the broader trend in online culture. Social media is filled with trends that promise to help people “maximize” or “optimize” different aspects of their health and lives. From fibermaxxing  to  looksmaxxing  and even  ballmaxxing , there seems to be a “maxxing” trend for almost everything. The latest example is “spermmaxxing,” a trend centered on improving sperm count, fertility, and overall reproductive health. The trend has led some males to try unverified methods to “maximize” their sperm, such as eating raw garlic and even dipping their testicles in ice water. One particularly concerning recommendation promoted by some influencers is testicle tanning. Experts say the practice may actually reduce sperm counts and increase the risk of testicular tumors. Why are males, especially younger males, increasingly interested in optimizing their sperm health? Growing concerns about male fertility have become a popular topic in certain corners of social media. While research has found evidence of declining sperm counts over the past several decades, many influencers are packaging those concerns into content designed to drive engagement, sell supplements, or promote lifestyle programs. But while some influencers may be capitalizing on male fertility anxiety and promoting questionable advice, experts say the increased focus on reproductive health isn’t necessarily a bad thing. “I’m not going to dismiss this entirely. The underlying instinct that men should be paying attention to their reproductive health is actually correct. But the execution is often somewhere between ineffective and absurd,” Philip Werthman , MD, board certified urologist, men’s health specialist, and director of the Center for Male Reproductive Medicine and Vasectomy Reversal in Los Angeles, CA, told Healthline. “Raw garlic and ice baths for your testicles aren’t going to move the needle in any meaningful clinical way. What concerns me more is that these trends fill a vacuum that medicine has created by largely ignoring male fertility. Men have historically been an afterthought in reproductive medicine, and when mainstream healthcare doesn’t engage them, they turn to social media. That’s a failure on our part as much as anything else,” he said. Werthman spoke to Healthline about spermmaxxing, male fertility, and how ejaculation can affect prostate cancer risk. This interview has been lightly edited for clarity and length. Why are sperm counts in younger men declining, and how severe is the drop? Werthman: The data is pretty alarming. Meta-analyses show sperm counts in Western men have dropped roughly 50–60% over the past four to five decades. That’s not noise, that’s a signal.  The causes are almost certainly multifactorial: endocrine-disrupting chemicals like phthalates and BPA , obesogenic diets (diets high in ultra-processed foods ), sedentary lifestyles , chronic psychological stress , heat exposure from laptops, cannabis use, and anabolic steroid abuse are all implicated. The obesity epidemic alone is a major driver — excess adipose tissue converts testosterone to estrogen and directly impairs spermatogenesis . We’re also seeing later-in-life fatherhood, which compounds the picture. This deserves far more serious public health attention than it’s getting. Are there ways men can increase their sperm counts naturally? Werthman: There’s quite a bit men can do. The evidence-based interventions include: optimizing weight eliminating or dramatically reducing alcohol and cannabis quitting tobacco getting adequate sleep managing heat exposure, such as no hot tubs, no laptops directly on the lap, loose-fitting underwear addressing nutritional deficiencies, particularly zinc , folate , vitamin D , and CoQ10 managing chronic stress For men who are actively trying to conceive, a semen analysis is the starting point — you can’t manage what you haven’t measured, and it’s cheap, noninvasive, and incredibly informative. What are signs of reproductive health issues in males? Werthman: Clinically, the signs can be subtle or frankly absent until a couple is struggling to conceive. That said, things I tell men to pay attention to: changes in ejaculatory volume pain or swelling in the testes or epididymis, a narrow tube at the back of each testicle erectile or ejaculatory dysfunction gynecomastia or changes in secondary sex characteristics reduced libido varicocele Hormonal symptoms like fatigue , mood changes, and loss of muscle mass can also reflect underlying hypogonadism that impacts fertility. Any man who’s been trying to conceive ...

More: Social media is filled with trends that promise to help people “maximize” or “optimize” different aspects of their health and lives. Experts say the practice may actually reduce sperm counts and increase the risk of testicular tumors. Werthman spoke to Healthline about spermmaxxing, male fertility, and how ejaculation can affect prostate cancer risk.

TL;DR: What are signs of reproductive health issues in males?

Read original at Healthline →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Sciencedaily Jun 12, 03:12

Scientists found a smarter Mediterranean diet that slashes diabetes risk by 31%

A large European study revealed that a lower-calorie Mediterranean diet paired with exercise and coaching dramatically reduced the risk of type 2 diabetes. Participants who made these lifestyle changes were 31% less likely to develop the disease over six years. They also lost more weight and trimmed their waistlines compared to those following a standard Mediterranean diet alone.

More: Scientists found a smarter Mediterranean diet that slashes diabetes risk by 31%. Participants who made these lifestyle changes were 31% less likely to develop the disease over six years. They also lost more weight and trimmed their waistlines compared to those following a standard Mediterranean diet alone.

TL;DR: A large European study revealed that a lower-calorie Mediterranean diet paired with exercise and coaching dramatically reduced the risk of type 2 diabetes.

Read original at Sciencedaily →

Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Sciencedaily Jun 12, 03:12

Eating more beans and soy could slash high blood pressure risk by nearly 30%

Eating more beans, lentils, chickpeas, tofu, and other soy foods could be a surprisingly powerful way to fight high blood pressure. A major analysis of studies from around the world found that people with the highest intake of legumes were 16% less likely to develop hypertension, while those eating the most soy foods had a 19% lower risk.

More: Eating more beans, lentils, chickpeas, tofu, and other soy foods could be a surprisingly powerful way to fight high blood pressure. A major analysis of studies from around the world found that people with the highest intake of legumes were 16% less likely to develop hypertension, while those eating the most soy foods had a 19% lower risk.

TL;DR: Eating more beans, lentils, chickpeas, tofu, and other soy foods could be a surprisingly powerful way to fight high blood pressure.

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Sciencedaily Jun 12, 03:12

Surprising research reveals why you shouldn't add bananas to your smoothies

Researchers found that adding bananas to berry smoothies can dramatically reduce the body’s ability to absorb healthy flavanols. The surprising discovery shows that even simple food combinations can change how much nutrition your body actually gets.

More: Surprising research reveals why you shouldn't add bananas to your smoothies. Researchers found that adding bananas to berry smoothies can dramatically reduce the body’s ability to absorb healthy flavanols. The surprising discovery shows that even simple food combinations can change how much nutrition your body actually gets.

TL;DR: Researchers found that adding bananas to berry smoothies can dramatically reduce the body’s ability to absorb healthy flavanols.

Read original at Sciencedaily →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 11, 20:47

A New Vaccine Was Designed by AI and Safey Tested on Humans

A new vaccine designed by AI is the first to be tested on humans and may protect against a wide range of coronaviruses related to SARS and COVID-19. miodrag ignjatovic/GettyImages Researchers have tested a vaccine designed to protect against a range of coronaviruses. This new vaccine was the first designed by AI to be tested on humans . The pEVAC-PS vaccine could enable protection against future mutations. The use of AI also enables the development of new vaccines much faster. However, more research is needed to determine whether it works in a more diverse population. According to an article found in the June 2026 issue of the Journal of Infection , researchers have safely tested a new vaccine designed to protect against a wide range of coronaviruses related to SARS and COVID-19. As a press release from the University of Cambridge explains, this trial is the first time that a vaccine whose active component was designed entirely by computer simulations has been tested in humans. This vaccine, developed by a team of scientists from the University of Southampton, the University of Cambridge, and DIOSynVax Ltd., is called pEVAC-PS. The technology uses a “super-antigen” designed by artificial intelligence (AI) to create protection against a wide range of viruses, even when mutations occur. Current methods for developing vaccines lack this ability, making frequent reformulations necessary to keep up with ever-changing viruses. While the vaccine was found to be safe and without significant side effects, the authors say a larger trial is needed to determine whether it can provide strong protection in a more diverse population. AI-designed vaccine tested on humans for the first time In the study, it was given to healthy volunteers in the U.K. between December 2021 and September 2023. The goal was to create a vaccine that could defend not only against current COVID-19 variants but also against future coronavirus threats that might potentially jump from animals to humans. The authors say that the vaccine uses a needle-free DNA delivery system, making it easier to administer and store, especially in places with limited medical resources. This phase I clinical trial involved 39 healthy adults between the ages of 18 and 50 who had already received 2 or 3 doses of COVID-19 vaccines but had not recently contracted the virus. Participants were divided into four groups, each receiving different doses of the pEVAC-PS vaccine: 0.2 milligrams (mg), 0.4 mg, 0.8 mg, and 1.2 mg. The vaccine was administered twice: the first dose on day 0 and the second on day 28. Unlike traditional vaccines that use needles, pEVAC-PS was delivered intradermally (just under the skin) using a device called the PharmaJet Tropis, which delivers the vaccine without needles. This needle-free method reduces the need for specialized medical equipment and lowers the risk of needle-related injuries or infections. Volunteers were then carefully monitored for side effects and immune responses. They recorded any local reactions like redness or pain at the injection site, as well as systemic symptoms such as fever or fatigue, for seven days after each vaccination. Blood samples were collected at several points before and after vaccination to measure immune responses, including antibodies that target the spike protein receptor-binding domain (RBD) of SARS-CoV-1, SARS-CoV-2, and the vaccine construct itself. pEVAC-PS vaccine was safe with few side effects The pEVAC-PS vaccine was well tolerated by all participants, with no serious adverse events reported. Most side effects were mild or moderate and included expected reactions such as soreness at the injection site or mild fatigue. Additionally, no increase in side effects was observed with higher doses, and fewer side effects occurred after the second dose compared to the first. A small number of participants experienced mild COVID-19 infections during the trial, unrelated to the vaccine and requiring no medical attention. Regarding immune responses, the results were modest. The vaccine did not significantly boost antibody levels beyond those already present from prior COVID-19 vaccinations or infections. This was partly due to participants having varied histories of COVID-19 exposure and different vaccination schedules, according to the researchers, which made it difficult to measure the vaccine’s direct effects. That said, the highest dose group (1.2 mg) did show a small but statistically significant increase in antibodies targeting the vaccine’s designed spike protein region around six weeks after the first dose. Neutralizing antibodies, which can block viral infection of cells, were measured in the middle and highest dose groups. Some increases in neutralizing activity were seen against certain SARS-CoV-2 variants, including Delta and Omicron BA.1, but not against the original Wuhan strain or SARS-CoV-1. The authors say this suggests that while the vaccine may help improve protection against som...

More: AI-designed vaccine tested on humans for the first time In the study, it was given to healthy volunteers in the U.K. pEVAC-PS vaccine was safe with few side effects The pEVAC-PS vaccine was well tolerated by all participants, with no serious adverse events reported.

TL;DR: The authors say this suggests that while the vaccine may help improve protection against som...

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 11, 18:28

FDA Approves ‘New’ Sunscreen Ingredient Used in Europe and Asia for Years

Bemotrizinol (PARSOL Shield), an advanced sunscreen filter that has long been used in Europe and Asia, has been approved for use in the U.S. by the FDA. Image Credit: Photo by LumiNola/Getty Images The FDA has approved bemotrizinol (PARSOL Shield). This is the first new sunscreen ingredient approved in over 20 years, offering superior UVA and UVB protection. Consumers in the United States can expect new products featuring PARSOL Shield by the end of 2026, with broader availability to follow. This innovation closes the UVA protection gap and paves the way for more effective, cosmetically elegant sunscreens. The Food and Drug Administration (FDA) has approved bemotrizinol (PARSOL Shield), an advanced sunscreen filter that has long been used in Europe and Asia.  It is the first new sunscreen ingredient approved by the FDA in over 20 years and will offer consumers improved UVA protection. It will also pave the way for a new generation of sunscreens.  “Bemotrizinol has been used safely in Europe for decades, and [the] FDA’s action will increase competition and consumer confidence in sunscreen products,” HHS Secretary Robert F. Kennedy, Jr said in a press release .  Bemotrizinol (PARSOL Shield) is a chemical sunscreen filter that is recognized for its broad-spectrum UVA and UVB protection. It is photostable and effective at concentrations up to 6%. Unlike many older filters, bemotrizinol is absorbed minimally through the skin, with plasma levels rarely exceeding FDA thresholds . “This is exactly the kind of progress we can achieve when we modernize our processes and apply sound science to regulatory decisions,” Mike Davis , MD, Acting Director of the FDA Center for Drug Evaluation and Research (CDER), said in a press release . “The FDA is committed to ensuring the American consumer has access to the most effective and safe therapies, including over-the-counter products like sunscreens.” Why FDA approval of bemotrizinol is significant Bemotrizinol is the first new active ingredient added to an over-the-counter (OTC) monograph under the streamlined process established by the CARES Act . The approval of bemotrizinol aligns with the Make America Health Again (MAHA) strategy report priority that states, “FDA will promote innovation in the sunscreen market, and improve regulatory processes for over-the-counter sunscreen , which has fallen behind other countries.” Susan Mayou , a consultant dermatologist at the Cadogan Clinic in the United Kingdom, told Healthline that this FDA approval is an important development. “It introduces a modern UV filter that has been used safely and effectively in Europe and other parts of the world for many years. One longstanding criticism of the U.S. sunscreen market has been that consumers have had access to fewer advanced UV filters than those available internationally,” she said. “While existing U.S. sunscreens can provide excellent protection when used correctly, some of the newer filters available in Europe and elsewhere offer stronger UVA protection, improved stability in sunlight, and more cosmetically elegant formulations.”  The first products in the United States with the new ingredient are expected by the end of 2026 under the PARSOL Shield name. How to choose and use sunscreen When choosing and using a sunscreen , it is important to keep in mind the following: Look for “broad-spectrum” on the label, with SPF 30 or higher. Consider water resistance and suitability for your skin type. Use about 1 ounce (a shot glass full) for full-body application. Apply 15 minutes before sun exposure and reapply every 2 hours. Don’t forget ears, neck, hands, and other often-missed areas. How does bemotrizinol work differently? Bemotrizinol offers true broad-spectrum coverage and is highly photostable, meaning it does not degrade in sunlight. It is suitable for sensitive skin, with low risk of irritation and minimal systemic absorption. Formulations can be lighter and less likely to leave a white cast, especially compared to mineral-only sunscreens. “Unlike some older UV filters that protect only a narrow portion of the ultraviolet spectrum, bemotrizinol offers broad-spectrum coverage across both UVA and UVB rays,” said Mayou. “This is particularly important because UVB rays are primarily responsible for sunburn, while UVA rays penetrate deeper into the skin and contribute to premature aging, pigmentation, and skin cancer.” Mayou also told Healthline that bemotrizinol “is also highly efficient, providing strong protection at relatively low concentrations.” “This gives formulators greater flexibility to create sunscreens that are lightweight, comfortable to wear, and cosmetically elegant, without sacrificing protection. Ultimately, this can lead to products that people are more likely to apply correctly and use consistently, which is one of the most important factors in effective sun protection.”

More: FDA Approves ‘New’ Sunscreen Ingredient Used in Europe and Asia for Years. It is suitable for sensitive skin, with low risk of irritation and minimal systemic absorption. Ultimately, this can lead to products that people are more likely to apply correctly and use consistently, which is one of the most important factors in effective sun protection.”

TL;DR: Bemotrizinol (PARSOL Shield), an advanced sunscreen filter that has long been used in Europe and Asia, has been approved for use in the U.S.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Bbc Jun 11, 15:03

How do weight-loss drugs like Mounjaro and Wegovy work?

Home News US & Canada UK UK Politics England N. Ireland N. Ireland Politics Scotland Scotland Politics Wales Wales Politics Africa Asia China India Australia Europe Latin America Middle East In Pictu…

More: Home News US & Canada UK UK Politics England N. Ireland Politics Scotland Scotland Politics Wales Wales Politics Africa Asia China India Australia Europe Latin America Middle East In Pictures BBC InDepth BBC Verify Football 2026 Business World of Business Technology of Business NYSE Opening Bell Technology Artificial Intelligence Intelligence Revolution AI v the Mind Tech Now…

TL;DR: Wegovy and Mounjaro are available to certain patients on the NHS, and can also be bought privately.

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Further reading: EatRightWHO NutritionNutrition.govWikipedia

Bbc Jun 11, 08:47

What's really going on in your gut?

The gut is home to around trillions of microorganisms, including bacteria, viruses and fungi. What are they all doing down there!?

More: What's really going on in your gut?. The gut is home to around trillions of microorganisms, including bacteria, viruses and fungi. What are they all doing down there!?

TL;DR: The gut is home to around trillions of microorganisms, including bacteria, viruses and fungi.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jun 10, 17:35

More Than 1 Drink a Day Linked to Health Risks, Clashing With U.S. Guidelines

New research found that health risks accelerate after 1 drink per day. Oleg Breslavtsev/Getty Images New research suggests alcohol-related health risks may begin at lower levels of drinking than previously thought. Researchers found no clear health benefit from even moderate alcohol consumption and concluded that both men and women should limit intake to no more than 1 drink per day. The findings add to growing evidence that any amount of drinking may carry long-term health risks. A major new analysis suggests alcohol-related health risks may begin at lower levels of drinking. Researchers found no clear health benefit from low-level alcohol consumption and concluded that both men and women should limit intake to no more than 1 drink per day. The study concludes that the risk of alcohol-related death begins at lower levels of consumption than previously suggested by federal guidelines. The research, published on June 8 in the Journal of Studies on Alcohol and Drugs , estimated that the risk of death and other health risks begins with relatively small quantities. Researchers concluded that current U.S. alcohol guidance should recommend no more than 1 drink per day for both males and females. The findings add to growing evidence that even moderate or socially accepted levels of drinking may carry long-term health risks, making individualized conversations about alcohol use increasingly important. The new report was previously commissioned under the Biden administration to help inform the 2025–2030 Dietary Guidelines for Americans . Some of the findings were published in 2025 , but they did not include specific recommendations about the number of drinks per day. According to an editorial published alongside the study, the findings were not incorporated into the final guidelines released under the Trump administration. “Alcohol’s harmful effects on the body are well established, so these findings are not surprising. They reinforce the many biological pathways through which alcohol, especially in higher amounts, can negatively impact overall health,” said Ketan K. Thanki , MD, board certified colorectal surgeon with the MemorialCare Todd Cancer Institute at Long Beach Medical Center in Long Beach, CA. Thanki wasn’t involved in the study. Health risks accelerate after more than 1 drink a day Unlike previous studies that followed a single group of people over time, the new analysis combined multiple national datasets, including federal health surveys, mortality records, alcohol consumption data, and disease statistics. Researchers ultimately included 56 systematic reviews and meta-analyses for review. They found no statistically significant overall health benefit from low-level drinking. Instead, alcohol-related mortality risk began rising at relatively modest levels of consumption. The model estimated that lifetime alcohol-attributable mortality exceeded 1 death per 1,000 people at approximately 6.5 drinks per week for men and 7 drinks per week for females. Risk climbed quickly beyond that point. The estimated lifetime risk of an alcohol-related death exceeded 1 in 100 people at roughly 8.5 drinks per week for both males and females. For males consuming 14 drinks per week — the equivalent to the former U.S. recommendation of up to 2 drinks per day — the estimated lifetime risk of an alcohol-attributable death reached approximately 1 in 25, or 4%. The study also highlighted alcohol’s role in cancer risk. Researchers identified elevated risks for cancers of the throat , liver , colon and rectum , breast , and many others. Several cancer risks increased even at relatively low levels of alcohol consumption. The findings also suggest that how people drink matters in addition to how much they drink. Consuming larger amounts of alcohol on a single occasion, binge or heavy drinking , increases risks of breast cancer, cardiovascular events, injuries, suicide attempts , motor vehicle crashes, and interpersonal violence. In other words, two people consuming the same total amount of alcohol each week may face very different risks depending on their pattern of drinking. “What is clear is that heavy alcohol use, whether ongoing or occasional binge drinking, significantly increases the risk of a wide range of health problems,” Thanki told Healthline. The study also challenges one of the most persistent beliefs about alcohol, that moderate drinking protects heart health . Previous observational studies have suggested that moderate drinkers may experience lower rates of heart disease . However, the authors concluded that any apparent cardiovascular benefits were outweighed by alcohol’s harmful effects across a broader range of diseases and injuries.  “Alcohol use, especially heavy drinking, is a well-established risk factor for heart disease . It can raise blood pressure , contribute to weight gain , trigger abnormal heart rhythms , damage heart muscle, and increase the risk of heart attack and stroke ,” said Cheng-Han Chen ...

More: The study also highlighted alcohol’s role in cancer risk. The study also challenges one of the most persistent beliefs about alcohol, that moderate drinking protects heart health . It can raise blood pressure , contribute to weight gain , trigger abnormal heart rhythms , damage heart muscle, and increase the risk of heart attack and stroke ,” said Cheng-Han Chen ...

TL;DR: New research found that health risks accelerate after 1 drink per day.

Read original at Healthline →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 10, 12:40

Shaquille O’Neal Shares How Zepbound Helped with Sleep Apnea and Weight Loss

NEW YORK, NEW YORK – MAY 12: Shaquille O’Neal attends the 2026 Disney Upfront at Jacob K. Javits Convention Center on May 12, 2026 in New York City. (Photo by John Nacion/FilmMagic) Shaquille O’Neal is taking Zepbound to help manage his weight and reduce obstructive sleep apnea (OSA) symptoms. Zepbound is FDA approved for moderate to severe OSA in adults living with obesity. Excess weight, especially around the neck, can worsen OSA symptoms by narrowing the airway and increasing the risk of collapse during sleep. Shaquille O’Neal says taking Zepbound has helped improve symptoms of obstructive sleep apnea (OSA), a condition he has lived with for years. In 2011, the NBA legend was diagnosed with moderate obstructive sleep apnea after taking part in an overnight sleep study conducted at Harvard Medical School. “[The doctors] told me the what and whatnots to do and talked about certain things, but I ignored it…because I thought I was superhuman,” he told Healthline. OSA is often an obesity-related disease in which the airway in the throat repeatedly collapses or becomes blocked while sleeping, said Karl Nadolsky , DO, director of the diabetes & endocrinology clinic at The Gym and an assistant clinical professor of medicine at Michigan State University. “This causes you to briefly stop breathing multiple times per hour, leading to drops in oxygen, disrupted sleep, loud snoring, and daytime tiredness,” Nadolsky told Healthline. “Over time, untreated OSA can increase the risk of high blood pressure , heart disease, and other serious health problems.” Why O’Neal decided to take his sleep apnea more seriously After his diagnosis, O’Neal tried using a CPAP (Continuous Positive Airway Pressure) machine , which involved wearing a mask to help keep his airway open while sleeping. However, he said he didn’t use it effectively, so he stopped and his snoring continued to get worse. “My snoring got so bad that my friends started making…funny videos out of them. And then I was always tired during the daytime,” said O’Neal. O’Neal said moments like that helped him realize the importance of taking his health more seriously. “[I] got with my doctor, and my doctor’s like, ‘Uh, you know what? You should think about Zepbound.’” After discussing treatment options with his doctor, O’Neal decided to try Zepbound, a GLP-1 drug that is currently the only prescription medication that is FDA approved for moderate to severe OSA in adults with obesity. Since he began taking the medication, O’Neal said he’s experienced improvements in his OSA symptoms, including fewer breathing interruptions during sleep. Now he’s sharing his experience and using his platform to help raise awareness about the treatment option for others who are living with OSA, especially men who may be putting off seeking treatment. “The problem with men? We think we’re superhuman, especially athletic men. Because, you know, when you play, you never get sick, and you never catch the flu, you just think you’re [invincible],” said O’Neal. Why Zepbound may help reduce sleep apnea symptoms Zepbound may help with moderate to severe OSA by addressing obesity, which plays a significant role in OSA, said Alex Dimitriu , MD, founder of Menlo Park Psychiatry & Sleep Medicine. “Excess weight, especially around the neck, can narrow the airway and increase the risk of collapse during sleep,” he told Healthline. “Clinical evidence suggests that weight loss is highly effective in reducing disease severity.” Losing 10% to 15% of body weight can reduce OSA severity by as much as 50% in people with moderate obesity, Dimitriu said. Sleep apnea treatment often requires a personalized approach For people seeking ways to treat sleep apnea symptoms, O’Neal encourages people to talk with a healthcare professional. “If you’re experiencing snoring , daytime tiredness, fatigue, get with your doctor and let him prescribe what’s best for you,” O’Neal said. Dimitriu agreed, noting that several treatment options are available and that a doctor can help determine which is most appropriate. “CPAP remains the gold standard for treating OSA because it effectively uses pressurized room air to keep the airway open,” said Dimitriu. “Even while taking Zepbound, many patients with OSA may still require CPAP to manage their symptoms effectively, especially while the weight loss is in progress or if they have anatomical factors like a small jaw (and crowded teeth to prove it) that contribute to the obstruction,” he added. However, he also noted that many people like O’Neal have a hard time using CPAP, with roughly 30% to 60% of people using it consistently. “It’s exciting to see new pharmacologic options like GLP-1 agents being utilized for OSA, as CPAP adherence has historically been poor,” Dimitriu said. “There’s also a sleep apnea pill in the pipeline, but weight loss helps overall health in general, in addition to sleep, so it’s a win.” Why lifestyle changes still matter When O’Neal learned that a reduced-c...

More: Shaquille O’Neal Shares How Zepbound Helped with Sleep Apnea and Weight Loss. “Excess weight, especially around the neck, can narrow the airway and increase the risk of collapse during sleep,” he told Healthline. “Clinical evidence suggests that weight loss is highly effective in reducing disease severity.

TL;DR: “There’s also a sleep apnea pill in the pipeline, but weight loss helps overall health in general, in addition to sleep, so it’s a win.” Why lifestyle changes still matter When O’Neal learned that a reduced-c...

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 9, 17:56

Drinking Alcohol May Lead to Ultra-Processed Food Cravings. Here’s Why

New research found that more unhealthy, savory foods were consumed on drinking days versus non-drinking days. Jovana Milanko/Stocksy Drinking alcohol may lead to increased consumption of ultra-processed savory foods. Researchers found that alcohol can amplify the FGF21 hormone, which can cause cravings for protein and savory foods. Natural cravings for protein may be disrupted due to the widespread availability of ultra-processed foods that taste savory but lack protein. Drinking alcohol may cause people to over-consume savory ultra-processed foods.  Researchers at the University of Sydney found that alcohol consumption may amplify a biological drive for salty, umami-flavored foods. The findings were recently published in Obesity Reviews . “Many people will recognise the experience of having a few drinks and suddenly craving something salty, like chips, French fries, pizza or other savoury foods. Now we have a better understanding of the hormonal dynamic at play, which may be driving overconsumption of ultra-processed foods,” Amanda Grech , lead study author and a researcher at the Charles Perkins Centre at the University of Sydney, said in a press statement .  The research dovetails with mounting evidence showing that alcohol consumption in any amount is associated with negative health outcomes . If you choose to enjoy alcohol in moderation, here’s what you should know about pairing alcohol with your diet. More savory foods consumed on drinking days In conducting their study, the researchers examined data from the Australian National Nutrition and Physical Activity Survey (NNPAS) to explore patterns of food intake associated with alcohol consumption.  They found that more savory foods were consumed on drinking days than on non-drinking days.  For every standard drink consumed, there was an increase in savory food intake as well as a reduction in sweet food intake. The researchers say that drinking alcohol triggers an increase in levels of a hormone known as FGF21. This can cause cravings for salty or savory flavors. Traditionally, the human body associates savory flavors with protein-rich foods. But the researchers note that in the modern food environment, this association can be disrupted by the availability of umami and savory flavors in ultra-processed foods that are low in protein.  The availability of ultra-processed savory foods, often artificially flavored, can act as a “protein decoy,” tricking the body into seeking foods that might taste like they are protein-rich but don’t actually deliver protein.  As a result, people may consume more food to satisfy their cravings, leading to greater intake of total energy, carbohydrates , and fats.  “Our study suggests that when dietary protein is diluted, people compensate by eating more overall to satisfy the increased protein appetite induced by alcohol,” David Raubenheimer , senior study author and a researcher at the  Charles Perkins Centre, said in a press statement. “In this way, alcohol may contribute to overeating particularly when ultra-processed, low-protein savory foods are readily available,” he continued. How alcohol use may lead to unhealthy food cravings Wesley McWhorter , DrPH, MS, a spokesperson for the Academy of Nutrition and Dietetics, explained that hormones may play a role in food cravings associated with alcohol use . McWhorter wasn’t involved in the study. He cited FGF21, a metabolic hormone secreted by the liver that responds specifically to nutritional stress. “The hormone story is one piece, but it’s not the whole story. Alcohol lowers inhibition, so people are more likely to make food choices they might otherwise avoid,” he told Healthline. “Drinking often happens late at night, when people are tired, hungry, and making quick decisions — with limited options. There’s also the social environment; if everyone is ordering pizza or stopping for fast food, it becomes an easy default,” McWhorter said. “Alcohol can also affect blood sugar and appetite, which may make people feel genuinely hungry. And with a hangover , people are often dehydrated, tired, and craving something salty and satisfying. So it’s biology, environment, and convenience. What this study adds is a possible explanation for why those cravings often skew savory and salty rather than sweet,” he continued. The researchers note that alcohol can have different effects on total energy intake, depending on the “dietary environment” of the person consuming alcohol.  Whitney Linsenmeyer , PhD, a spokesperson for the Academy of Nutrition and Dietetics and an assistant professor of nutrition and dietetics at Saint Louis University, explained that food cravings associated with alcohol use may not be a bad thing if a person’s dietary environment has fewer ultra-processed foods and healthier options. Linsenmeyer wasn’t involved in the study. “Craving protein is not likely to be problematic when you’re reaching for fresh, nutrient-dense, lean cuts of meat, such as a pork tenderl...

More: McWhorter wasn’t involved in the study. Alcohol lowers inhibition, so people are more likely to make food choices they might otherwise avoid,” he told Healthline. “Alcohol can also affect blood sugar and appetite, which may make people feel genuinely hungry.

TL;DR: New research found that more unhealthy, savory foods were consumed on drinking days versus non-drinking days. Jovana Milanko/Stocksy Drinking alcohol may lead to increased consumption of ultra-processed savory foods.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jun 9, 14:52

AstraZeneca's New Oral GLP-1 Aids Weight Loss and Lowers Blood Sugar

AstraZeneca’s new oral GLP-1 pill showed promising results for weight loss and blood sugar in a phase 2 trial. Guido Mieth/Getty Images A new GLP-1 oral medication from AstraZeneca, known as elecoglipron, lowered blood sugar levels and led to 10.5% weight loss in a phase 2b clinical trial. Experts say GLP-1 drugs in tablet form may encourage more people to take these medications to help treat type 2 diabetes and obesity. When using any GLP-1 medication, it’s still important to maintain a healthy lifestyle, including regular exercise and a balanced diet. A new GLP-1 oral tablet has shown promising results in a phase 2b clinical trial for the treatment of type 2 diabetes. Officials at AstraZeneca report that their new medication, elecoglipron, helped people with type 2 diabetes reduce blood glucose levels and lose 10.5% of their body weight at 26 weeks. The results were reported at the  American Diabetes Association 2026 Scientific Sessions  in New Orleans and were published in The Lancet on June 8. AstraZeneca’s elecoglipron is the latest GLP-1 medication to be developed in pill form, rather than injectable treatments like  Ozempic,   Wegovy ,  Zepbound , and  Mounjaro . The first oral pill was  Rybelsus , a tablet manufactured by Novo Nordisk, initially approved by the Food and Drug Administration (FDA) in 2019 for adults diagnosed with type 2 diabetes. In December 2025, the FDA approved a new  Wegovy pill , also manufactured by Novo Nordisk, for weight loss treatment. In April, FDA officials gave the green light to  Foundayo , an oral tablet manufactured by Eli Lilly, which is also used for weight management. Experts not involved in AstraZeneca’s trial say the results are a promising step toward treating type 2 diabetes and obesity. “It’s exciting to see another new oral medication that reinforces the positive effects of non-injectable GLP-1 medications,” said Pouya Shafipour , MD, a family and obesity medicine physician at Providence Saint John’s Health Center in California. “The GLP-1 agonist market is expanding quickly and this study’s results indicate there may eventually be another oral GLP-1 agonist on the market if the phase 3 trial is successful and if the manufacturer seeks FDA approval,” added Marilyn Tan , MD, an endocrinologist and professor of medicine at Stanford University. AstraZeneca’s oral GLP-1 led to 10.5% weight loss The phase 2b SOLSTICE randomized placebo-controlled clinical trial involved 406 adults with type 2 diabetes. The participants were from nine countries, including the United States. The trial, which was funded by AstraZeneca, tested different starting doses, dose-escalation schemes, and maintenance doses over a 26-week period. The participants were assigned to different treatment groups, including those given a placebo. Researchers reported that nearly 90% of participants who took the medication achieved an  HbA1c level  of 7%, the standard target for average blood glucose levels. That compared with about 25% of participants who were administered a placebo. The researchers added that 72% of participants in the treatment groups achieved at least a 5% weight reduction with an average of 10.5% at 26 weeks. They also reported that the safety and tolerability of elecoglipron were similar to those of other GLP-1 medications at this stage of development. Shafipour noted that elecoglipron is still in the early stages of testing. He said a phase 3 clinical trial is necessary to determine the new drug’s effectiveness and safety. “So far, however, from the data that’s been collected, it looks like it’s very effective,” Shafipour told Healthline. Tan was equally encouraged. “Newer agents appear to be more effective at A1c and weight lowering, and it’s a very exciting time for the treatment of type 2 diabetes and obesity when the new GLP-1 agonists are able to achieve more robust A1c lowering than any other existing diabetes medication other than insulin ,” she told Healthline. “The weight loss is also beneficial for multiple other metabolic diseases associated with obesity.” What to know about GLP-1 drugs GLP-1 medications were originally utilized to treat type 2 diabetes by lowering blood glucose levels. However, researchers began to notice that these drugs were also effective in suppressing appetite , helping promote weight loss . Since then, researchers have reported that GLP-1 medications may also help with heart health , along with other benefits. Mir Ali , MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California, said GLP-1 medications have changed the medical landscape, especially in the treatment of obesity. “They’re the best option we have right now,” he told Healthline. “They’ve created a shift in thinking in terms of treating obesity as a long-term chronic condition.” “They have really adjusted treatment to a more metabolic approach,” added Shafipour. Shafipour said there are advantages to ...

More: AstraZeneca's New Oral GLP-1 Aids Weight Loss and Lowers Blood Sugar. Experts say GLP-1 drugs in tablet form may encourage more people to take these medications to help treat type 2 diabetes and obesity. Since then, researchers have reported that GLP-1 medications may also help with heart health , along with other benefits.

TL;DR: AstraZeneca’s new oral GLP-1 pill showed promising results for weight loss and blood sugar in a phase 2 trial.

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 8, 15:09

Flavanol-Rich Fruits, Veggies May Be Best for Heart Health. Here's Why

Research shows that certain fruits and vegetables may be higher in flavanols, which improve heart health. Image Credit: Alex_Schmidt/Getty Images A recent study has found that most people are not getting enough flavanols in their diet. Flavanols are naturally occurring compounds that are found in various foods and drinks, including fruits and vegetables. Research has found that eating around 500 mg of flavanols per day can reduce your risk of death from cardiovascular disease. Not all fruits and vegetables are equal. Some have higher levels of flavanols than others. Eating plenty of fruits and vegetables is an important part of a healthy and balanced diet. The current Dietary Guidelines for Americans recommends 2–3 servings of fruits and vegetables each day. The  United Kingdom’s National Health Service (NHS)  takes this a step further and recommends 5 portions of fruits and vegetables each day.  Whichever recommendation you choose to follow, a recent study publi shed in  Food and Function  found that most people are not getting enough flavanols in their diets to protect heart health.  The researchers note that some fruits and vegetables are higher in flavanols than others. This doesn’t mean you shouldn’t eat the lower-level ones, but it may mean you want to eat more of the higher-level ones, especially if you’re concerned about cardiovascular disease risks. “Flavanols can significantly reduce the risk of dying from cardiovascular disease , but only if you consume enough of them,” Javier Ottaviani , PhD, director of the Core Laboratory of Mars Edge, part of Mars Inc, and lead author of the study, said in a press statement . “Most people assume that eating plenty of fruit and vegetables covers this, but what this research shows is that the specific choices you make matter far more than the total amount. Including a handful of blackberries, a whole apple, or having a cup of green tea alongside your meal could make a real difference to how much of these beneficial compounds you actually consume and absorb from the diet,” Ottaviani continued. Flavanols help lower cardiovascular disease risk by 27% The study tracked the diets of 30,000 participants across the United Kingdom and the United States using biomarker measurements. Previous research from the largest randomized controlled study on polyphenols , COSMOS , found that eating 500 milligrams (mg) of flavanols daily helped lower the risk of death from cardiovascular disease by up to 27%.  This study used data from COSMOS to develop and assess the hypothesis that adhering to current recommended amounts of fruit and vegetables meets the 500mg of flavanols daily. It then used EPIC Norfolk to assess replication in an independent, population-based sample with differing dietary patterns. The researchers found that most people fell well short of meeting the 500mg of flavanols each day, even when following standard healthy eating guidance from sources like the Dietary Guidelines for Americans and the NHS Eating Well guide. “This study highlights the value of being more intentional within broader food groups. While all fruits can fit into a healthy diet, regularly choosing flavanol-rich options like berries and apples may offer added cardiovascular benefits,” said Michelle Routhenstein , preventive cardiology dietitian at EntirelyNourished. Routhenstein wasn’t involved in the study. “This is not about focusing on a few ‘ superfoods ,’ but about thoughtfully including evidence-based, nutrient-rich choices within an overall balanced dietary pattern. The overall diet remains most important, with these findings helping refine which foods may provide an extra layer of heart protection,” she told Healthline. Which fruit, veg are high in flavanols? According to other research , there are certain fruits and vegetables that have the highest levels of flavanols: Plums (500 g): approximately 450mg of flavanols  Cranberries (250 g): approximately 300mg of flavanols  Blackberries (200 g): approximately 250mg of flavanols  Green tea (one 250 ml cup): approximately 200mg of flavanols  Broad beans or fava beans (80 g): approximately 140mg of flavanols  Cherries (400 g): approximately 130mg of flavanols  Apples with skin (200 g, or one medium apple): approximately 110mg of flavanols  Strawberries (200 g): approximately 90mg of flavanols  Blueberries (150 g): approximately 80mg of flavanols  Pinto beans (40 g, 2 Tbsp dry): approximately 70mg of flavanols “Rather than focusing on adding every flavanol-rich food, I find it is more sustainable to choose one or two favorites and make them a consistent part of the diet,” said Routhenstein. “For example, someone who enjoys berries could add them to breakfast several times per week, while a tea drinker might benefit from incorporating a daily cup of green or black tea . Small, enjoyable habits are often the most effective way to increase flavanol intake and support long-term heart health,” she added. The study findings may raise q...

More: Research has found that eating around 500 mg of flavanols per day can reduce your risk of death from cardiovascular disease. Routhenstein wasn’t involved in the study. The study findings may raise q...

TL;DR: Research shows that certain fruits and vegetables may be higher in flavanols, which improve heart health.

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 7, 13:54

An Avocado a Day May Keep Diabetes, Hypertension, and Obesity at Bay

Research shows that eating more avocado can reduce your risk of diabetes, hypertension, and obesity. Image Credit: Anjelika Gretskaia/Getty Images Research suggests that females who eat 30–38 grams of avocado per day may have a lower risk of diabetes.  A recent study also found that eating one avocado and 1 cup of mango each day may help lower blood pressure in people with prediabetes. A new study found that eating fresh avocado each day may help improve your body’s blood sugar response, lower diabetes risk, and reduce cardiometabolic risks. Avocados can provide various health benefits , including improving heart and gut health. Recent research has examined other potential benefits of regularly adding avocados to your diet. One 2025 study found that females who ate 30–38 grams of avocado per day may have a lower risk of diabetes than those who didn’t eat it. No significant association was shown in males, however. Another recent study showed that eating 1 avocado and 1 cup of mango each day helped improve heart health and lower blood pressure in people with prediabetes in as little as 8 weeks. A recent study published in Current Developments in Nutrition also found that eating fresh avocado daily may help improve blood sugar response, lower diabetes risk, and lower other cardiometabolic risk factors.  There are many ways you can add avocado to your diet and get the full spectrum of health benefits. Avocado may help lower diabetes risk A 2025 study showed that a daily dose of avocado may help reduce the risk of diabetes in females. “Given what we know about the nutritional profile of avocados — they have good unsaturated fats, a good source of fiber , and a multitude of vitamins, minerals, and phytonutrients , I’m not surprised to see these findings suggesting that eating avocados may play a role in lower diabetes risk,” registered dietitian Wendy Bazilian told Healthline in an earlier interview . Bazilian wasn’t involved in the study.  The study found that females who consumed 30–38 grams of avocado per day had a lower risk of diabetes than those who didn’t. While the study didn’t show the same association in males, experts say this may be due to lifestyle factors, such as more males in the study being smokers, or hormonal differences between males and females. Not only can eating avocado help reduce the risk of diabetes, but you don’t have to eat a lot of it each day to reap the benefits.  Daily avocado, mango helps lower blood pressure A study published in February found that combining avocado and mango could improve heart health and lower blood pressure in people with prediabetes.  Karen E. Todd , a registered dietitian nutritionist at The Supplement Dietitian, told Healthline in an earlier interview that while the findings of the study are promising, it doesn’t mean that a mango-avocado combination is a magic bullet. Todd wasn’t involved in the study.  The researchers found that eating one avocado and 1 cup of mango each day may help improve heart health in as little as 8 weeks.  Participants who followed the avocado and mango diet showed improvements in flow-mediated dilation (FMD), a measure of blood vessel function. Their FMD rose to 6.7%, whereas the control group’s FMD fell to 4.6%. This indicates better vascular health among those who consume the fruit combination. Males also saw a notable improvement in diastolic blood pressure . Those in the control group experienced an average central blood pressure increase of 5 mmHg, while males in the avocado–mango group saw a reduction of around 1.9 mmHg. “The sample size was relatively small, with 82 participants enrolled and 68 completing the protocol,” Brett A. Sealove , MD, chair of cardiology at Hackensack Meridian Jersey Shore University Medical Center, and associate professor and vice chair of cardiology, Hackensack Meridian School of Medicine, told Healthline in an earlier interview. Sealove was not involved in the study.  “The study duration was only 8 weeks, which is brief, given that vascular and metabolic remodeling typically occurs over several months. The study was also partially controlled, as participants prepared some of their own meals, introducing variability,” Sealove noted. Despite the limitations, the study still showed that adding more avocado and mango to your diet can help improve heart health. Tips to add avocado to your diet There are many ways you can add avocado into your diet, aside from simply eating them by themselves. stuffed avocados, add an egg into half an avocado, and bake it until the egg is set added to scrambled eggs guacamole added to soup added to salads used as a substitute for mayonnaise or sour cream used in ice cream used as a substitute for shortening, butter, oil, or eggs in baking added to smoothies If you do wish to eat avocado on its own, you can season it, grill it, pickle it, or have it on top of toast. Avocado may reduce cardiometabolic risk A new study found that consuming avocado daily can...

More: Avocados can provide various health benefits , including improving heart and gut health. Despite the limitations, the study still showed that adding more avocado and mango to your diet can help improve heart health. Avocado may reduce cardiometabolic risk A new study found that consuming avocado daily can...

TL;DR: Research shows that eating more avocado can reduce your risk of diabetes, hypertension, and obesity.

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 6, 13:28

Peptide Injections Touted as ‘Fountain of Youth.’ Spoiler Alert: They’re Not

Influencers tout peptide injections for fitness and longevity, but experts warn of health and safety risks. Mariya Borisova/Getty Images Injectable “wellness” peptides have become wildly popular among health and wellness enthusiasts, despite lacking credible evidence for their safety and effectiveness. Social media influencers and biohackers tout wellness peptides as a “fountain of youth” to achieve longevity and fitness gains. Experts in the medical community have raised alarms about the safety of compounded peptides marketed for wellness, calling for federal oversight of these products, which are largely sold online. During the 1980s, anabolic steroids emerged out of elite athletic circles and rose to popularity among fitness and gym enthusiasts. It didn’t take long for the medical community to question their safety. Researchers and athletic organizations raised concerns over the health risks associated with recreational anabolic steroid use, such as cardiovascular disease . By 1991, the substances were banned for non-medical use under the Anabolic Steroids Control Act . But the quest for fast-tracked, unproven methods to achieve peak fitness is far from over. Today, influencers and biohackers tout peptide injections as a “fountain of youth,” a one-stop shop to achieve muscle gain, longevity, and more. Echoing the past, so-called “wellness” peptides have become ubiquitous despite lacking any credible evidence. No studies to date have verified their safety for use in humans. A recent position paper by the Institute for Safe Medication Practices on the safety and efficacy of wellness peptides highlights an “alarming safety concern” about their widespread use. Unlike well-studied commercial peptide drugs (i.e., insulin and GLP-1s ), compounded peptide products marketed for “wellness” are unregulated by the Food and Drug Administration (FDA). While no states have outright banned non-FDA-approved peptides, some have stepped up public health messaging, aiming to crack down on online sales. For instance, Alabama’s medical regulator recently issued a warning against the use of non-FDA-approved research-grade peptides due to health and safety risks. The FDA is expected to decide in July whether certain compounded wellness peptides should be officially authorized for use .  Experts are concerned that Health and Human Services Secretary Robert F. Kennedy Jr., an avid supporter of peptides who oversees the FDA, could ease some of the red tape. “This has nothing to do with wellness,” said Bert Mandelbaum , MD, sports medicine specialist, orthopedic surgeon, and co-director of the Regenerative Orthobiologic Center at Cedars-Sinai Orthopedics in Los Angeles.  “I would call it more of an uninformed fad. It’s worse than that — it’s criminal. The influencers, including RFK Jr., are abusing the system and not following the science,” he told Healthline. Healthline spoke with Mandelbaum to learn more about the dangers of unregulated peptides and why most people should probably steer clear. This interview has been lightly edited and condensed for clarity and length. What are wellness peptides? Mandelbaum: Peptides are a group of compounds that come together to have a wide variety of functions in our body. Peptides are leucine, the amino acid that’s fantastic for building muscle, and it’s been well studied . Since peptides are protein derivatives, they’ve been exploited on social media. The peptides BPC-157 , TB-500, and CJC-1295 have been marketed by influencers for anything from performance to joint healing to fat loss and anti-aging. They’re just peptides that are being abused. There’s no research, there’s no label, there’s no associated effects. Fortunately, our real athletes haven’t fallen prey to this. The good news is we have biologics that can make a difference in many of the things that peptides claim to do. If you’re a bodybuilder and you’re trying to build your muscles, you might think that peptides are going to do it for you. At one time, that was about anabolic steroids and combinations of anabolic steroids, but we have since proven the titanium to be unsafe. Are compounded peptides illegal? Mandelbaum: In the sense of the legality of these self-injections, this whole thing is a farce. From a regulatory perspective, they’re not FDA-approved. They’re banned by the World Anti-Doping Administration (WADA), the Department of Defense (DoD), and the Department of Justice (DoJ). BP-157 (15-amino acid pentadecapeptide) is a synthetic derivative of human gastric juice, and it’s promoted online as having incredible healing capabilities and also for performance and longevity, none of which have ever been substantiated in anything other than rodents. It’s almost like a group of gym rats got together and said, “Let’s see how much of this stuff we could sell.” It’s totally unregulated. What are the risks of wellness peptide injections? Mandelbaum: There are risks, some of which we don’t know, like tumor risk, for exa...

More: Researchers and athletic organizations raised concerns over the health risks associated with recreational anabolic steroid use, such as cardiovascular disease . There’s no research, there’s no label, there’s no associated effects. Mandelbaum: There are risks, some of which we don’t know, like tumor risk, for exa...

TL;DR: Influencers tout peptide injections for fitness and longevity, but experts warn of health and safety risks.

Read original at Healthline →

Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jun 5, 17:21

Oura Ring 5: Upgraded Smart Ring Takes Your Health, Fitness to the Next Level

is smaller and has upgraded features to improve how you track your health and fitness. Image courtesy of Oura Ring Oura Ring has announced the release of the newest generation of its smart ring. The Oura Ring 5 promises to be smaller, more proactive, and more personalized than before.  With the new software portfolio, Oura Ring includes upgraded features that help track more than 50 metrics. Oura rings are smart devices that help you track your health and fitness. The smart rings track sleep metrics, activity and fitness, and women’s health, such as period tracking. The Oura Ring 5 , released on June 4, promises to deliver even more insights than previous generations. Every Oura ring has helped you track various health metrics, such as: sleep timing and quality sleep regularity sleep oxygen levels average heart rate activity level step count female fertility windows period cycle days and phases Oura Ring 5 offers even more features and personalized tracking. “Oura Ring 5 is a big step toward our vision of giving every body a voice. By reimagining Oura Ring 5 to be smaller and easier to wear, and pairing it with our most advanced software yet, we’re making it possible for many more people to wear Oura every day—and to benefit from the personalized, predictive health insights that come with it,” Tom Hale , CEO at Oura, said in a statement . What makes Oura Ring 5 different? The new Oura Ring 5 is 40% smaller than previous generations, making it the smallest smart ring. It is lighter in order to be more comfortable both day and night. It also has upgraded, precision sensors to achieve better skin contact, greater consistency, and improved accuracy across more finger types and skin tones. Alongside the new ring launch, Oura is also releasing a new portfolio of software that promises to make the app more proactive, personalized, and useful in daily life. New software features include: Health radar: This includes two new proactive capabilities in addition to the existing experiences — blood pressure signals and nighttime breathing. Live activity tracking: This lets you start a workout directly in the app and view key metrics in real time. It also improves the accuracy of automatic activity detection for more than 40 activities, including low-motion workouts like yoga and Pilates . GLP-1 insights: This brings together information people often track in multiple apps, such as dosing, side effects, and weight. It provides a single longitudinal view of your GLP-1 journey, along with Oura insights, so you can see how your medication and daily habits work together over time. Oura Ring 5 also offers the same long battery life as previous generations. This smaller ring still allows 6 to 9 days between charges. It is also waterproof up to 100 meters. The Oura Ring 5 comes in six finishes and starts at $399.

More: Oura Ring 5: Upgraded Smart Ring Takes Your Health, Fitness to the Next Level. Oura rings are smart devices that help you track your health and fitness. GLP-1 insights: This brings together information people often track in multiple apps, such as dosing, side effects, and weight.

TL;DR: is smaller and has upgraded features to improve how you track your health and fitness.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline Jun 5, 14:38

FIFA World Cup: Biggest Health Risks for Fans and How to Avoid Them

Experts say the World Cup may put pressure on the standard health protection guidelines. Image credit: Photo by wakila/GettyImages Public health experts are concerned that the 2026 FIFA World Cup may test the public health playbook.  While Ebola and measles may not pose a high risk for these games, the spread of other respiratory illnesses is possible, as are heat-related illnesses. The CDC and other government agencies are putting plans in place to help protect people from health concerns. There are steps you can take to protect yourself from infectious diseases and other health issues while attending World Cup games this summer. The FIFA World Cup kicks off on June 11 and is expected to draw millions of spectators to North America. The international tournament is hosted by 16 cities across the United States, Canada, and Mexico and runs through July 19. Fans can expect 104 games from 48 teams , with the opening match featuring Mexico vs. South Africa in Estadio Azteca in Mexico City. There is generally a well-established “ playbook ” for protecting the public’s health during mass events like this. However, there are also broader circumstances this year that experts believe could put that playbook to the test. With any mass gathering , there’s always a risk of common respiratory illnesses spreading among crowds. However, all three countries hosting the World Cup this year have also seen a recent resurgence in measles, which is highly contagious and can be deadly among unvaccinated individuals. Still, the risk of measles transmission at the games is low. Despite concerns over Ebola and hantavirus, experts say it’s unlikely these rare diseases would circulate during the World Cup. In past tournaments, heat-related illnesses posed the greatest threat during matches, which typically take place outdoors in the summer months. Of course, there’s also the risk of mosquito bites , which is more of a nuisance than anything else. “The most common issue was heat-related illness, with falls, diabetes, seizures, and chest pain also noteworthy,” said William Schaffner , MD, professor of medicine, health policy, and infectious diseases at Vanderbilt University. “A fundamental concept is preparation — planning by all the relevant agencies. We have done this well before and ought to be able to manage the World Cup events also,” he told Healthline. Risk of measles, Ebola remains low The current Ebola outbreak in the Democratic Republic of Congo and Uganda poses a global health concern. The World Health Organization (WHO) has described the outbreak as a “public health emergency of international concern.” However, the risk of Ebola spreading at the World Cup remains low. “The risk of importing Ebola is very low. If such should occur, with heightened awareness, the patient should be diagnosed promptly and can be cared for safely by U.S. hospitals and personnel using rigorous infection control procedures,” said Schaffner. “Remember, Ebola does not spread readily, in contrast to influenza and COVID .” Another potential concern is measles amid recent surges in across the United States, Canada, and Mexico. However, experts say the risk of measles during the games remains low. “It is possible that there could be importations of measles or other vaccine-preventable illnesses,” Schaffner said. “Given the less-than-optimal vaccination rates in the U.S., there could be limited spread to unvaccinated persons. This would be detected quickly and would evoke a public health response. Again, the risk of this happening is low.” CDC aims to minimize health risks at World Cup Government organizations, such as the Centers for Disease Control and Prevention (CDC), are working hard to plan for and mitigate potential health risks during the World Cup. “CDC is actively engaged in World Cup preparedness as part of the federal coordination structure led by the White House FIFA World Cup 2026 Task Force,” a CDC spokesperson told Healthline. “As part of HHS, CDC is regularly engaging with public health departments in host cities, other federal agencies, and partner organizations.” The CDC is also using its Insight Net Cooperative Agreement Program to work with partners to assess importation risk and the potential for outbreaks of pathogens of concern. “At U.S. ports of entry, CDC Port Health maintains around-the-clock protocols for identifying and responding to ill travelers arriving from international destinations, in coordination with U.S. Customs and Border Protection,” said the CDC spokesperson. The CDC has also developed a dedicated World Cup data dashboard (currently in final development) to provide state and local health departments with enhanced visibility into disease trends within and beyond their jurisdictions. You can also visit the CDC Safety for Soccer Fans . It gives health and safety tips to help keep players, travelers, and visitors safe this summer. Healthline contacted WHO for more information on how it is preparing for ...

More: FIFA World Cup: Biggest Health Risks for Fans and How to Avoid Them. The CDC and other government agencies are putting plans in place to help protect people from health concerns. “The risk of importing Ebola is very low.

TL;DR: Experts say the World Cup may put pressure on the standard health protection guidelines.

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 4, 18:44

Diseases Like Measles, Whooping Cough Rising Due to Low Vaccination Rates

Doctors say a rise in infectious disease rates in the U.S. is largely due to declining vaccination rates. Luis Velasco/Getty Images Doctors are reporting increases in infectious diseases, including measles, whooping cough, rotavirus, and others, especially in children. Experts say the primary reason for the rise of these illnesses is the increasing number of adults and children who are not vaccinated. They say it’s important for medical professionals to educate their patients about the safety and effectiveness of vaccines. Doctors are reporting what they describe as an alarming rise in a variety of serious illnesses due to declining vaccination rates. Measles is a significant concern amid ongoing outbreaks in the United States, but concerns about whooping cough , rotavirus , and other diseases are also mounting. Children who aren’t vaccinated appear to be bearing the brunt of these illnesses, but officials also note an increase in unvaccinated adults requiring hospitalization, including some who refuse tetanus shots and blood transfusions . The news comes a week after President Donald Trump signed an  executive order  reaffirming an assessment by the Department of Health and Human Services (HHS) that aligns “the United States’ childhood vaccine practices with scientific evidence and best practices from peer, developed countries.” The executive order notes that in 1980, the Centers for Disease Control and Prevention (CDC) recommended children in the United States receive 23 vaccine doses in seven shots against seven different diseases. In 2024, that number had risen to at least 84 vaccine doses in at least 57 shots for 17 diseases, more than any other developed nation. In January, HHS officials led by Health Secretary Robert F. Kennedy Jr. released a new  childhood vaccination schedule  that recommended vaccination against 11 diseases. The six other diseases were recommended only for children at higher risk. “After an exhaustive review of the evidence, we are aligning the U.S. childhood vaccine schedule with international consensus while strengthening transparency and informed consent . This decision protects children, respects families, and rebuilds trust in public health,” Health Secretary Kennedy said in a  statement  at the time. However, experts who spoke with Healthline say the decrease in vaccination rates and the resulting increase in disease are worrisome. “I am very concerned about the increase in cases of vaccine-preventable infections in children in the United States,” said William Schaffner , MD, a professor of medicine at Vanderbilt University in Tennessee and a specialist in infectious diseases. “Large measles outbreaks have been well-publicized; less well known are recent increases in whooping cough and rotavirus (diarrheal) infections in children,” he said. “There also have been clusters of chickenpox . All these illnesses can make children feel miserable, and that would be bad enough, but all can result in serious illness that requires hospitalization and can cause death.” Measles cases rising in U.S. By late May, the CDC reported 30 measles outbreaks in 2026, resulting in 1,983 cases. In 2025, there were 48 measles outbreaks with 2,288 confirmed cases. The major measles outbreaks this year have occurred in South Carolina, with 669 cases so far. Utah is next with 484 cases, followed by Texas with 182 and Florida with 139. About 21% of this year’s cases involve children under 5. About 72% involve children and young adults 19 years and younger. About 6% of cases this year have required hospitalization, compared to 11% last year. So far, no deaths related to measles have been reported this year. Last year, three deaths were recorded. The CDC reports that 92% of measles cases this year involve unvaccinated individuals or those with unknown vaccination status. “Measles infection can result in serious complications, hospitalization, and death. Vaccination remains a critical tool for the prevention of measles infection and severe disease,” CDC officials wrote in another report . Health experts recently told the New York Times that measles can be a harbinger of things to come. They say that’s because measles is highly contagious and can be the first disease to spike as vaccination rates broadly decline. Graham Tse , MD, a pediatrician and chief medical officer of MemorialCare Miller Children’s & Women’s Hospital in California, is among the physicians noticing the trend. Tse said that his facility had gone more than two decades without a measles case. Now, these cases are starting to crop up. “I’m deeply concerned,” he said. “We’re talking about a disease that can have serious consequences,” Tse said the reason for the increase in cases is simple. “It’s vaccine hesitancy,” he said. “It’s because more and more people aren’t getting vaccinated.” Rising rates of other infectious diseases Increasing rates of infectious diseases have spread beyond measles, raising alarms among experts. Meghan Hof...

More: This decision protects children, respects families, and rebuilds trust in public health,” Health Secretary Kennedy said in a  statement  at the time. Health experts recently told the New York Times that measles can be a harbinger of things to come. “We’re talking about a disease that can have serious consequences,” Tse said the reason for the increase in cases is simple.

TL;DR: The six other diseases were recommended only for children at higher risk.

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 4, 13:58

Drinking Alcohol Can Raise Your Risk of These 20 Health Conditions

Research shows that any amount of drinking can increase your health risks. Image Credit: Catherine Falls Commercial/Getty Images A recent study found an association between alcohol consumption and 20 different health outcomes.  The findings show that any amount of alcohol may increase the risk for various cancers.  The researchers noted that the effects of alcohol can vary based on factors like sex, age, drinking patterns, and other behavioral risk factors.  The study found that there is no evidence to support sex-specific thresholds on alcohol guidelines. It’s well-established that consuming alcohol can have negative effects on overall health. The Centers for Disease Control and Prevention (CDC) states that moderate drinking may have health risks, while the World Health Organization (WHO) warns that no amount of alcohol is safe.  A new study found that any alcohol consumption can raise the risk for major cancers, including colorectal cancer, breast cancer, and pancreatic cancer. The findings, published on June 1 in Nature Health , show associations between alcohol use and several additional health outcomes, including other forms of cancer.  The researchers noted that while there are limitations to the study, the results present a clearer picture of the risks associated with alcohol consumption to help inform personalized decisions about alcohol use. “This is not surprising and illustrates the many mechanisms through which alcohol, especially when consumed in large amounts, is toxic to our bodies,” said Ketan Thanki , MD, board certified colorectal surgeon with the MemorialCare Todd Cancer Institute at Long Beach Medical Center in Long Beach, CA. Thanki wasn’t involved in the study.  Low-to-moderate alcohol use linked to health risks Even moderate alcohol consumption may increase the risk for certain health conditions, especially cancers.  The study analyzed 843 cohort and case-control studies published through 2023 using the Burden of Proof meta-analytic framework.  The researchers aimed to systematically re-evaluate the relationship between alcohol consumption and 20 health outcomes. These included 10 types of cancer:   breast colorectal esophageal laryngeal liver lip and oral pharyngeal pancreatic prostate stomach It also included four cardiovascular diseases: atrial fibrillation and flutter ischemic stroke hemorrhagic stroke ischemic heart disease The study included six other conditions as well: Alzheimer’s disease and other dementias cirrhosis and other chronic liver diseases lower respiratory infections pancreatitis tuberculosis type 2 diabetes Alcohol use raises risk of multiple health conditions by up to 50% Alcohol raised the risk of five health outcomes by 15–50%, including: lip and oral cavity cancer laryngeal cancer cirrhosis and other chronic liver diseases pancreatitis colon and rectal cancer The strongest association was between alcohol consumption and pharyngeal cancer, with a 105% increased risk. Any amount of alcohol consumption appeared to increase the risk for pharyngeal cancer more than the other health conditions that were considered.  Nine outcomes met the criteria for an increased risk of developing a health condition by 0–15% or, in some cases, a decrease in risk by 0–13%. These included: esophageal cancer breast cancer Alzheimer’s disease and other dementias atrial fibrillation and flutter type 2 diabetes liver cancer pancreatic cancer lower respiratory infections prostate cancer There were five health outcomes that showed weak or inconsistent evidence: stomach cancer, hemorrhagic stroke, ischemic stroke, tuberculosis, and ischemic heart disease.  Effects of alcohol use on type 2 diabetes The researchers found some evidence that the risk of type 2 diabetes actually decreased with low consumption of alcohol and increased with higher consumption. However, this is not to say that you should start drinking alcohol if you currently don’t.  “While I readily recognize the role that alcohol consumption plays in the human experience, when anyone asks me about safe alcohol consumption, I always begin by saying that abstinence is the safest and truest bet,” Matt Glowiak , PhD, licensed counselor and chief addiction specialist with Recovered, told Healthline. Glowiak was not involved in the study. “If one is going to drink, it is within their legal right if of age. However, they must make themselves fully aware of the health implications, which extend greatly beyond any warning label posted directly on beverage labels,” he said. Reducing alcohol intake may improve health While current CDC guidelines define moderate drinking as 2 drinks per day for males and 1 drink per day for females, the WHO states that no safe amount of alcohol is safe for health. CDC alcohol consumption guidelines The CDC defines moderate alcohol use as: 2 drinks or less per day for males 1 drink or less per day for females In the United States, 1 standard drink is equivalent to :  1.5 o...

More: Drinking Alcohol Can Raise Your Risk of These 20 Health Conditions. Any amount of alcohol consumption appeared to increase the risk for pharyngeal cancer more than the other health conditions that were considered.  Nine outcomes met the criteria for an increased risk of developing a health condition by 0–15% or, in some cases, a decrease in risk by 0–13%.

TL;DR: Research shows that any amount of drinking can increase your health risks.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Bbc Jun 4, 11:19

Could gut parasites be influencing your behaviour?

Could the parasite also impact human behaviour? Made in partnership with UKRI.

More: Could gut parasites be influencing your behaviour?. Could the parasite also impact human behaviour? Made in partnership with UKRI.

TL;DR: Could the parasite also impact human behaviour?

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Further reading: WHO NutritionPubMed NutritionNutrition.govWikipedia

Healthline Jun 3, 18:18

GLP-1s Like Ozempic May Help Lower Breast Cancer Risk. Here’s How

New research suggests that GLP-1 drugs could serve as an effective strategy for breast cancer prevention. ruizluquepaz/Getty Images A new study found that females using GLP-1 drugs had about a 30% lower risk of developing breast cancer. The effect may be related to the metabolic improvements associated with this class of medications . More research is needed before GLP-1 drugs can be recommended for breast cancer prevention. Experts say that regular screening and a healthy lifestyle remain important preventive measures. A new study from the University of Pennsylvania has found that women who take GLP-1 medications are about 30% less likely to develop breast cancer. Semaglutide, the active ingredient in GLP-1 drugs like Ozempic and Wegovy , mimics a hormone called glucagon-like peptide-1, which helps regulate blood sugar and appetite. GLP-1 medications were originally developed to treat type 2 diabetes , but are also widely prescribed for weight loss. The new research raises hope that GLP-1 drugs could serve as a strategy for breast cancer prevention , especially among higher-risk females with overweight and obesity . The study was presented at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting and published on June 2 in  JCO Oncology Practice . The findings come at a moment when scientists are exploring the use of GLP-1 drugs to treat other conditions beyond type 2 diabetes and obesity, such as sleep apnea and addiction . Examining GLP-1 use prior to breast cancer diagnosis The research team conducted a retrospective cohort study using electronic health records from the University of Pennsylvania Health System, which includes both academic and community medical sites across Pennsylvania and New Jersey. During this process, they identified 217,624 females who underwent breast imaging between January 1, 2022, and June 30, 2025. The study focused on 111,646 females ages 45 to 80 who were overweight or obese (BMI ≥ 25) and had documented breast imaging outcomes. Among these participants, 15,264 (13.7%) had been prescribed GLP-1 medications prior to their imaging exam, while 96,382 (86.3%) had no record of GLP-1 use. To ensure a fair comparison and reduce bias, the researchers performed a one-to-one case-control matching. Each woman taking GLP-1 drugs was matched with a woman not taking the drugs, based on factors such as age, race, ethnicity, BMI, breast density, and diabetes status. This matching process helped control for variables that could independently influence breast cancer risk, independent of GLP-1 use. The primary outcome measured was the diagnosis of new breast cancer during the study period. Statistical modeling was used to analyze the association between GLP-1 exposure and breast cancer incidence. GLP-1s associated with reduced breast cancer risk The researchers’ analysis found a significant association between GLP-1 use and reduced breast cancer risk. Females taking GLP-1 medications had about 35% lower odds of developing breast cancer compared to those who did not use these drugs in the full cohort. In the matched cohort, which controlled for potential confounding factors, GLP-1 use was associated with a 30.5% reduction in breast cancer incidence. Specifically, among the 15,264 females on GLP-1 drugs, 1.62% were diagnosed with breast cancer during the study, compared to 2.47% of the 96,382 females who did not use GLP-1 medications. This translated into an absolute risk reduction of about 0.69%. The protective effect of GLP-1 medications was consistent across racial groups, including Black and white females, and was independent of diabetes status, age, BMI, and breast density. The researchers believe several mechanisms could explain these findings. GLP-1 drugs not only promote weight loss , which is known to reduce breast cancer risk, but they also reduce systemic inflammation , a known contributor to cancer development. Laboratory studies have also shown that GLP-1 agonists may directly inhibit cancer cell growth and alter metabolic pathways essential to tumor survival. While the study was observational and cannot prove causation, its large sample size and rigorous matching lend weight to the results. However, the researchers emphasized that prospective clinical trials are necessary to definitively determine whether GLP-1 medications can prevent breast cancer and to understand the underlying biological mechanisms. This study opens the door to exploring GLP-1 drugs as a potentially safer alternative to existing breast cancer preventive medications, which often have significant side effects. Given the widespread use of GLP-1 medications for weight management and diabetes, the findings could have significant public health implications. Are GLP-1s the future of breast cancer prevention? Monique Gary , DO, a breast surgical oncologist at St. Luke’s University Health Network who wasn’t part of the research team but did attend the conference, said that GLP-1 could be exerting this ...

More: GLP-1s Like Ozempic May Help Lower Breast Cancer Risk. ruizluquepaz/Getty Images A new study found that females using GLP-1 drugs had about a 30% lower risk of developing breast cancer. GLP-1s associated with reduced breast cancer risk The researchers’ analysis found a significant association between GLP-1 use and reduced breast cancer risk.

TL;DR: New research suggests that GLP-1 drugs could serve as an effective strategy for breast cancer prevention.

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Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 2, 22:00

Just 2 Hours of Strength Training a Week May Help You Live Longer

Researchers say that 90–120 minutes of strength training per week can help reduce the risk of early death. Image Credit: People Images/Getty Images A new study found that 90–120 minutes of strength training each week could help promote longevity. Around 1.5 to 2 hours of weekly strength training lowered the risk of death from cardiovascular and neurological diseases, and death from any cause.  The findings add to the known health benefits of strength training, including bone health, improved balance, and weight management.  Strength training is heralded as a valuable aspect of an exercise regimen and regular physical activity. Strength and resistance training offer myriad benefits , including improving bone strength and balance, and helping with weight management.  A new study found that aiming for 90-120 minutes of strength training each week may help lower your risk of death.  The 30-year study, published on June 2 in the British Journal of Sports Medicine , found no additional benefits from more than 120 minutes of strength training.  This means for most people, around 1.5 to 2 hours per week is sufficient for overall health and longevity. “It is important to engage in aerobic exercise that increases the heart rate. This new study finds [that] another important aspect of exercise is strength training, including free weights, weight machines, and body weight exercises,” said Clarinda Hougen , MD, a primary care sports medicine specialist at Cedars-Sinai Orthopedics in Los Angeles. Hougen wasn’t involved in the study. “By training and growing your muscle mass, you can improve your metabolic health and help reduce cardiovascular risk,” Hougen told Healthline. 1.5 to 2 hours of strength training lowers death risk by 13% The researchers for this study drew on 30 years of data from three large groups of study participants: Health Professionals Follow-up Study, 1992–2022 Nurses’ Health Study, 2002–21 Nurses’ Health Study II, 2003–21 These totaled 147,374 participants, of whom 31,540 were males, and 115,834 were females. The average age at the beginning of the study was 54. Participants were questioned every 2 years about the time they spent on strength training and aerobic exercise each week for up to 30 years. Aerobic exercise included: brisk walking running or jogging swimming cycling tennis and squash, strenuous outdoor work stair climbing Strength training included exercises using weights or body weight, such as push-ups, lunges, and squats. During the course of the study, 35,798 participants died. A higher weekly and long-term level of strength training was associated with a lower risk of death. The researchers found that 90–119 minutes per week of strength training was associated with a 13% lower risk of death from any cause. No further benefits were seen above 120 minutes per week. Lower risk of cardiovascular, neurological deaths The researchers found that 90–120 minutes of weekly strength training was associated with a 19% lower risk of dying from cardiovascular disease. The same amount of strength training also lowered the risk of death from neurological disease by 27%.  A lower risk of cancer was only seen at lower levels of strength training. A 9% lower risk was observed at 1–29 minutes per week, and an 12% lower risk at 30–59 minutes per week. As this is an observational study, no firm conclusions of cause and effect can be drawn. The researchers also acknowledge the study’s limitations. These limitations include the self-reported nature of the data, the exclusion of strength-training activities such as calisthenics and Pilates, and the lack of information on the duration of each exercise session or the intensity of strength training, any of which might have influenced the findings. However, the findings still show an association between regular strength training and mortality rates and overall health. “This particular study reported an optimal range of 90–120 minutes per week, although benefits may be seen with lower targets. This adds to a growing body of already established evidence touting these benefits,” said Mary Greene , MD, board certified cardiologist with Manhattan Cardiology in NYC. Greene wasn’t involved in the study.  What counts as strength training? When you think of strength training , you may automatically think of exercising with weights. However, there are other ways to add strength training to your routine, even if you don’t have weights. resistance band training push ups squats lunges gardening yoga Pilates Other benefits of strength training This study focuses on the mortality benefits of strength training. But there are various other benefits of this type of exercise as well. Greene told Healthline some of the other benefits of strength training include: cardiovascular benefits, such as lowered blood pressure , improved cholesterol , improved endothelial function (blood flow, inflammation control, and cardiovascular health) metabolic health, such as a de...

More: Hougen wasn’t involved in the study. “By training and growing your muscle mass, you can improve your metabolic health and help reduce cardiovascular risk,” Hougen told Healthline. Greene told Healthline some of the other benefits of strength training include: cardiovascular benefits, such as lowered blood pressure , improved cholesterol , improved endothelial function (blood f…

TL;DR: Researchers say that 90–120 minutes of strength training per week can help reduce the risk of early death.

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Further reading: PubMed NutritionNutrition.govWHO NutritionWikipedia

Healthline Jun 2, 13:57

Groundbreaking New Drug Nearly Doubles Pancreatic Cancer Survival

An experimental new pill, daraxonrasib, significantly improved survival rates of participants with pancreatic cancer. Israel Sebastian/Getty Images A new medication performed remarkably well in a phase 3 clinical trial for treating pancreatic cancer. The drug daraxonrasib reduced the risk of death by nearly half, as well as shrank tumors in people who were given the drug. Pancreatic cancer has the highest mortality rate of all major cancers, and early detection is the key to treating the disease. A new type of medication is showing promise in the treatment of pancreatic cancer, one of the deadliest forms of cancer. In a phase 3 clinical trial, the drug daraxonrasib significantly improved survival rates of participants with pancreatic cancer who had previously been treated with chemotherapy. The researchers found that daraxonrasib reduced the overall risk of death by 60% compared with people with advanced pancreatic cancer who were treated with chemotherapy. The medication also helped shrink or eliminate tumors among participants in the trial. The findings were recently published in the  New England Journal of Medicine  and presented at the American Society of Clinical Oncology (ASCO) 2026 annual meeting from May 29 to June 2 in Chicago, IL. Officials at  Revolution Medicines , the manufacturer of daraxonrasib, said the clinical trial results are a major breakthrough in pancreatic cancer treatment. “These results represent a potentially transformative advance for patients and underscore daraxonrasib’s potential to redefine the treatment landscape,” said Mark Goldsmith , MD, the chief executive officer and chairman of Revolution Medicines, in a statement . Experimental pancreatic cancer drug shows promise The RASolute 302 clinical trial involved a total of 500 participants with solid tumors and activating RAS mutations , a gene mutation found in the cancer cells of 92% of pancreatic cancer cases. Participants were given doses of between 10 milligrams (mg) and 400 mg of daraxonrasib orally once a day, with 300 mg selected as the phase 3 dose. The researchers focused on 168 participants who had been previously treated with chemotherapy. The researchers reported that participants using daraxonrasib had an average survival rate of 13 months from diagnosis to death compared to 6 months for participants treated with standard chemotherapy. In people with a known RAS mutation called G12, tumors remained ⁠under control for a median of about 7 months among participants on daraxonrasib compared to about 3 months for those treated with chemotherapy. The percentage of patients whose cancer shrank or disappeared was about 33% in patients with the G12 mutation compared to about 12% for people given chemotherapy. Overall, about 31% of trial participants saw their tumors shrink or disappear compared with 11% who received chemotherapy. Experts not involved in the trial are very encouraged by the findings. “This is an extraordinarily hopeful moment for the pancreatic cancer field,” said Diane Simeone , MD, the director of the UC San Diego Moores Cancer Center, as well as the founder and chief scientific advisor of the Pancreatic Cancer Early Detection Consortium ( PRECEDE ), in a statement shared with Healthline. “Pancreatic cancer patients have had far too few effective treatment options,” she added. “The progress around daraxonrasib shows what is possible when long-term scientific investment, academic discovery, and industry innovation come together,” Simeone continued. Christina Annunziata , MD, senior vice president of Extramural Discovery Science at the American Cancer Society (ACS), was also buoyed by the research. “These results are extremely promising since this drug doubled overall survival for patients with relapsed pancreatic cancer,” she told Healthline. Side effects of daraxonrasib Daraxonrasib is the first in a new class of drugs called RAS(ON) inhibitors that target variants of the RAS gene that drive cancer growth. Side effects were reported in 96% of participants who received doses of 300 mg or less. Those included: rash diarrhea nausea stomatitis mucositis vomiting fatigue Side effects were grade 3 or higher in about a third of participants. Annunziata, however, noted that “the side effects were lower compared to standard chemotherapy typically used in this second-line treatment setting.” However, she had concerns about access to the new medication. “The only concern will be the availability of this drug to people who need it. This will depend on the cost and level of insurance coverage,” Annunziata said. Why is pancreatic cancer so deadly? Pancreatic cancer has the highest mortality rate of all major cancers. The American Cancer Society (ACS)  reports  that 68,000 Americans will be diagnosed with pancreatic cancer this year, and roughly 53,000 will die from the disease. Pancreatic cancer affects the pancreas, an organ that plays an essential role in digestion by producing enzymes that the body needs...

More: The drug daraxonrasib reduced the risk of death by nearly half, as well as shrank tumors in people who were given the drug. The researchers found that daraxonrasib reduced the overall risk of death by 60% compared with people with advanced pancreatic cancer who were treated with chemotherapy. “The only concern will be the availability of this drug to people who need it.

TL;DR: An experimental new pill, daraxonrasib, significantly improved survival rates of participants with pancreatic cancer.

Read original at Healthline →

Further reading: EatRightNutrition.govWHO NutritionWikipedia

Healthline Jun 2, 09:33

Anne Hathaway Was ‘Legally Blind’ for a Decade Due to Early Onset Cataract

Anne Hathaway recently shared how an early onset cataract left her legally blind in one eye for a decade. Getty images Anne Hathaway recently shared about the early onset cataract that left her legally blind in one eye for 10 years. The Centers for Disease Control and Prevention (CDC) states that 17.2% of Americans ages 40 and older have a cataract in one or both eyes. Cataracts generally begin to occur in people over 40, but they can and often do occur in people younger than this. Academy Award and Golden Globe-winning actor Anne Hathaway recently spoke out about the early onset cataract that left her nearly legally blind for 10 years. “I was half blind for 10 years — age 30 to 40,” Hathaway told the New York Times’ Popcast in an earlier interview. “I had an early onset cataract, and it affected my vision so much that I was basically legally blind out of my left eye.” Hathaway said she underwent surgery to fix her cataract. “I didn’t realize how bad it had gotten until I could finally see the full spectrum,” she told the Popcast. According to the Centers for Disease Control and Prevention (CDC) , around 20.5 million (17.2%) Americans ages 40 and older have a cataract in one or both eyes. While cataracts typically develop after age 40, they can occur in younger people. Cataracts are common among middle-aged and older adults. They affect approximately 94 million people globally and are one of the leading causes of vision impairment. “Everyone will develop at some point in their lifetime, and while they typically begin forming between ages 40 and 50, we do see cases that develop earlier, often referred to as early onset cataracts,” said Ashley Brissette , MD, an ophthalmologist and eye surgeon specializing in cataract surgery in New York City. Healthline spoke with Brissette to learn more about early onset cataracts and how they’re treated. This interview has been lightly edited for clarity and length. What causes early onset cataracts? Brissette: These earlier cases may be influenced by factors such as genetics, certain medical conditions, medications, or environmental exposures. So while early onset cataracts are less typical, they are not uncommon, and they are a reminder to pay attention to changes in your vision at any age. Do early onset cataracts always lead to blindness? Brissette: Cataracts can progress to significantly impact vision if left untreated. As the lens becomes more clouded, patients may experience blurred or cloudy vision, difficulty seeing at night, and faded colors. The old thinking was to wait until cataracts became advanced before removing them surgically, but a more modern approach is to remove them as soon as they affect your vision and quality of life. We have excellent options for lens implants that are placed inside the eye after cataract surgery. These lenses can provide a range of vision to limit the need for glasses after surgery. The important thing to know is that this kind of vision loss is treatable with modern cataract surgery. What are the signs of early onset cataracts? Brissette: Early signs of cataracts are often subtle and easy to overlook. Patients may notice: blurry or cloudy vision increased sensitivity to light or glare difficulty seeing at night colors appearing faded needing brighter light for everyday tasks Over time, cataracts can also affect independence and quality of life, contributing to reduced mobility and an increased risk of falls. If something feels different with your vision, do not ignore it. Regular eye exams are key because cataracts develop gradually. How are early onset cataracts treated? Brissette: In the early stages, some patients can manage with stronger lighting or updated glasses. But when cataracts begin to interfere with daily life, surgery is the standard, highly effective, and safe treatment. And it can help you see better with less dependence on glasses. Cataract surgery is one of the most common procedures performed in the United States. What’s really exciting today is how much the procedure has evolved. We are not just removing the cataract. We are replacing it with an intraocular lens that can correct vision. With advanced technologies, including some of the latest presbyopia correcting options, I am seeing patients achieve a range of vision that can significantly reduce their need for glasses. In many cases, patients are not just getting back the vision they had before their cataract. They are actually seeing better than they did before it developed. One of the biggest misconceptions is that cataracts are just something you have to live with, but that is not true. Cataracts are highly treatable, and addressing them can make a meaningful difference not just in vision, but in overall quality of life, from maintaining independence to reducing risks like falls and even reducing the risk of dementia. The key takeaway is to stay proactive. The earlier we evaluate changes in vision, the more options we have to deliver t...

More: Anne Hathaway Was ‘Legally Blind’ for a Decade Due to Early Onset Cataract. The important thing to know is that this kind of vision loss is treatable with modern cataract surgery. And it can help you see better with less dependence on glasses.

TL;DR: Cataracts generally begin to occur in people over 40, but they can and often do occur in people younger than this.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline Jun 1, 20:24

Waist-to-Hip Ratio May Offer Better Indicator of Obesity, Health Over BMI

BMI measurements may drastically underestimate obesity rates among U.S. adults, new research suggests. Thomas Barwick/Getty Images A growing body of evidence suggests that a waist-to-hip ratio (WHR) measurement is a better indicator of obesity and health than body mass index (BMI). New research suggests that BMI measurements may be significantly underestimating the number of U.S. adults with obesity, which can lead to other chronic diseases. Experts say obesity misdiagnoses may be preventing people from getting the treatments that they need. New research suggests that body mass index (BMI) may be drastically underestimating the number of people in the United States with obesity. Around a quarter of people considered to have a healthy BMI measurement may actually meet the standard of having obesity, which raises the risk of various chronic health conditions. Researchers say that half of those classified as “overweight” based on their BMI should be reclassified as having obesity. The findings were published on June 1 in the Annals of Internal Medicine . The authors said that measurements of abdominal fat may be better indicators of obesity. They noted that people who are misdiagnosed based on BMI may not be getting the medical intervention they need or qualify for pharmacologic or surgical treatments for obesity. In addition, physicians may not flag these patients as needing lifestyle modifications that could improve their health. “Many people assume that if their BMI says they are not obese, they don’t have to worry about the many health problems linked to obesity,” said Brian P. Lee , MD, a hepatologist and liver transplant specialist with Keck Medicine and principal investigator of the study, said in a statement . “Our findings show that millions of Americans may already have obesity-related health impacts and may be missing needed health interventions.” BMI may not accurately measure obesity For their study, researchers from Keck Medicine at the University of Southern California examined data from the National Health and Nutrition Examination Survey (NHANES) . They included results from more than 5,600 participants, with an average age of 49, who’d been tested for BMI and hip and waist circumferences , such as the waist-to-hip ratio (WHR) . They concluded that 26% of people with a “normal” BMI and 50% of people with an “overweight” BMI actually qualified as having obesity. “BMI is problematic because it does not specifically measure body fat and instead reflects total body weight , which includes muscle and bone,” Lee said in a statement. “So, a muscular person can have a very high BMI but not have excess fat, while someone without much muscle can have a normal BMI but have excess fat causing health problems.” David Cutler , MD, a family medicine physician at Providence Saint John’s Health Center in California, who wasn’t involved in the study, said that, based on BMI, some professional athletes might be classified as overweight or obese when, in reality, they are in peak shape. “All you have to do is watch a football game to see that,” he told Healthline. Mir Ali , MD, a bariatric surgeon, bariatric medicine specialist, and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California, said that while BMI alone isn’t the most accurate measure of obesity, there are reasons for its use. Ali wasn’t involved in the study. “I agree that BMI is not the ideal indicator of obesity and that measuring the waist-to-hip ratio offers certain advantages,” he told Healthline. “However, BMI remains the most widely used measure by providers and insurance companies because it is easier to calculate, whereas waist-to-hip measurements can vary.” Is the waist-to-hip ratio a better indicator of health? In recent years, research has suggested that the waist-to-hip ratio (WHR) may be a more accurate measure of overweight and obesity. For instance, a 2023 study found that WHR measurements had the strongest association with all-cause mortality risk regardless of a person’s BMI. The authors suggested that body fat distribution, rather than body weight, should be considered in clinical recommendations. Cutler said he favored waist-to-hip ratio measurements over BMI. “BMI measures weight. The others measure fat. They’re two different things,” Cutler said. Ali noted that WHR, DEXA scans , and body roundness can more accurately determine whether a person has obesity. “However, these methods have not been widely adopted due to drawbacks like cost and complexity,” he said. “While BMI fails to account for body composition — potentially categorizing muscular individuals as overweight — it will likely remain the standard until a more effective, simple calculation is established,” Ali continued. Dan Azagury , MD, an associate professor of surgery at Stanford University and the medical director at the Stanford Lifestyle and Weight Management Clinic, shared similar thoughts. Azagury wasn’t invo...

More: Waist-to-Hip Ratio May Offer Better Indicator of Obesity, Health Over BMI. “Many people assume that if their BMI says they are not obese, they don’t have to worry about the many health problems linked to obesity,” said Brian P. Ali wasn’t involved in the study.

TL;DR: “BMI measures weight.

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Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia

Healthline May 30, 13:55

Beer, Body Scent May Make You a Mosquito Magnet. Can DEET Help?

Some people are more prone to mosquito bites than others, and scientists may have figured out why. Jaromir/Getty Images Researchers have identified several reasons why mosquitoes are more attracted to some people than others. The scent you give off through carbon dioxide and through your skin can make you more prone to mosquito bites. Mosquitoes may also be more attracted to people who drink beer. While DEET offers protection, research suggests that mosquitoes could evolve to become attracted to it. If you’ve ever felt like you’re a mosquito magnet, you’re not alone. Research shows that mosquitoes may be more attracted to some people than others. A 2026 preprint study found that mosquitoes are also more attracted to those who drink beer compared to those who don’t. Other recent studies have found that mosquitoes are attracted to the carbon dioxide (CO2) humans exhale.  Older studies suggest that mosquitoes may be attracted to chemical odors emitted by your skin. Regardless of what attracts them, it’s safe to say that no one wants to be their next meal. “Mosquitoes are said to be the most dangerous animals on our planet because they can transmit serious infections, including malaria , yellow fever , Zika , dengue , and chikungunya, among others,” said William Schaffner , MD, professor of infectious diseases at Vanderbilt University. Schaffner wasn’t involved in the studies. “Thus, learning how to avoid mosquito bites has long been a public health priority. It is a common experience that mosquitoes seem to have a preference for some persons while avoiding others,” he told Healthline. DEET has long been considered the gold standard repellent for protection against mosquito bites . However, a new study found that mosquitoes may have learned how to associate DEET with food and even become attracted to it. Of course, this doesn’t mean you should stop using DEET altogether. Any protection against mosquitoes is better than none at all. Whether you plan to travel this summer or attend World Cup matches, you may need to take extra precautions against mosquitoes, especially if you’re more prone to bites than others. Here’s what you need to know. Why are some people tastier to mosquitoes than others? Mosquitoes are attracted to the CO2 we exhale. They can fly up a CO2 “plume” that a person creates when they breathe and find a host. However, whether they land or not may depend on other factors. Some studies have pointed to our unique heat signatures as a reason mosquitoes may choose to land and feed on some people rather than others. Mosquitoes may be more attracted to stronger heat signatures. Other studies have found that mosquitoes may be attracted to chemical odors emitted by human skin. People who are more attractive to mosquitoes appear to produce more carboxylic acids. Carboxylic acids are naturally occurring compounds. They are found in human sweat and generated by skin microbes. Researchers believe that understanding how mosquitoes are attracted to certain skin odors may help develop more effective repellents. A recent study at a festival also found that what you drink may be more likely to attract mosquitoes. The researchers examined mosquito behavior among 465 participants from the festival. They found that factors such as consuming beer appeared to attract mosquitoes more. The researchers noted that this may be due to the smell of beer attracting mosquitoes rather than blood alcohol levels. However, they also note that further research is needed to verify the findings. “This study, conducted during a music festival in the Netherlands, suggested that mosquitoes were attracted to the skin of persons who had consumed beer,” Schaffner said. “However interesting, the result is inconclusive and must be confirmed by further research. It is unlikely that this study will result in a notable reduction in beer consumption.” DEET: It’s what’s for dinner A recent study published in the Journal of Experimental Biology found that mosquitoes may begin to associate the smell of DEET with food and even become attracted to it. The researchers trained mosquitoes by gradually introducing DEET and using a bag of warm blood kept just out of reach. As the mosquitoes began feeding on blood, the team introduced DEET into their environment. After repeating this process 4 times, they found that more than 60% of the mosquitoes attempted to feed when presented only with the smell of DEET. The insects were then given a choice of human hands. The “untrained” mosquitoes avoided the DEET-covered hand, while the “trained” ones were drawn to it. “The common assumption has always been that repellents work because of their chemistry — that DEET simply smells bad to mosquitoes and they flee or that its chemistry prevents mosquitoes from smelling us,” Clément Vinauger , associate professor of biochemistry at Virginia Tech, and co-author of the study, said in a press release . “But what we are showing is that the mosquito’s bra...

More: Research shows that mosquitoes may be more attracted to some people than others. However, a new study found that mosquitoes may have learned how to associate DEET with food and even become attracted to it. A recent study at a festival also found that what you drink may be more likely to attract mosquitoes.

TL;DR: A recent study at a festival also found that what you drink may be more likely to attract mosquitoes.

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Further reading: Nutrition.govEatRightWHO NutritionWikipedia

Healthline May 29, 11:36

Only 20% of Sunscreens Meet Safety Standards. What to Know Before You Buy

The EWG reports that only 20% of sunscreens meet safety standards. Image Credit: Ani Dimi/Stocksy Only about 20% of sunscreens meet leading safety and efficacy standards, according to a recent report from the Environmental Working Group (EWG). Mineral sunscreens are generally considered safer, but the best sunscreen is one you use consistently and reapply regularly. Broad-spectrum SPF 30 to 50, proper application, and regular reapplication are the keys to effective sun protection. Sunscreen is a key aspect of sun protection, especially in the summertime. However, your sunscreen may not be protecting you as well as you think.  According to a recent report by the Environmental Working Group (EWG) , only about 20% (550 out of 2,784) of SPF products met its rigorous safety criteria in 2026. The EWG rates products based on five factors that relate to ingredient hazard and efficacy in providing sun protection: health hazards UVB (ultraviolet B) protection UVA (ultraviolet A) protection balance of UVA and UVB protection sunscreen stability, or how quickly ingredients break down in the sun While sunscreen is important, it shouldn’t be the only thing you rely on to protect yourself from the sun.  “The recent report from the Environmental Working Group raises some important points about sunscreen formulation, labeling, and regulation, but it is also important to interpret the findings based on what is available,” said Tanya Evans , MD, board certified dermatologist and medical director of the Skin Cancer Program at the Melanoma Clinic at MemorialCare Saddleback Medical Center in Laguna Hills, CA. Evans wasn’t involved in the report.   “Sunscreen is still one of the most effective tools we have to reduce sunburn, photoaging, and skin cancer risk, including melanoma. The main message should not be to avoid sunscreen, but instead to choose and use sunscreen wisely,” she told Healthline.  Sunscreen regulatory gaps and industry responses There have been no fully approved new UV-blocking ingredients for sunscreen since 1999. For 27 years, Americans have relied on older filters, while products with safer, potentially more effective filters have become standard across Europe and Asia.  The Food and Drug Administration (FDA) proposed classifying bemotrizinol as a safe and effective sunscreen ingredient in late 2025. This would be the first time in decades that a new filter was allowed in U.S. markets. However, this has not yet been fully approved.  Mineral vs. chemical sunscreen Paul Banwell , a cosmetic surgeon and skin cancer specialist, said that as awareness of sunscreen ingredients broadens, more people are asking about the differences between chemical and  mineral sunscreens . Banwell wasn’t involved in the report. “Mineral sunscreens usually contain zinc oxide or titanium dioxide and sit on the skin to physically reflect UV rays away, whereas chemical sunscreens absorb UV radiation and convert it into heat,” Banwell told Healthline. “Neither is automatically ‘good’ or ‘bad’ and both can be effective, but certain skin types may tolerate one better than the other. In my clinic, particularly after procedures like laser resurfacing, peels, or surgery, I will often recommend mineral sunscreens because they tend to be gentler on healing or more reactive skin,” he said. Evans agreed and noted that the “best” sunscreen is the one that’s used every day. Protecting yourself from the sun year round It’s important to apply sunscreen properly to get the most protection during sun exposure.  Aim to apply 6 to 8 teaspoons of sunscreen to your entire body as an adult. Apply sunscreen 15 to 30 minutes before going out in the sun. Reapply sunscreen liberally at least every 2 hours. You should also consider other options besides sunscreen for sun protection : Try to plan outdoor activities outside of the peak hours, 10 a.m. to 4 p.m., when the sun’s rays are most intense.  Wear a hat and other protective clothing to cover your skin. Try to spend as much time as you can in the shade. Choosing a safe and effective sunscreen With so many options available, choosing the most effective sunscreen may seem daunting. “When choosing a sunscreen, I always tell patients to keep it simple and focus on the basics,” Banwell said. Evans offered the following tips when choosing sunscreen:  Look for broad-spectrum protection (covers both UVA and UVB). SPF 30 to 50 is sufficient for most people, but most dermatologists recommend SPF 50 or higher. Use water resistance when swimming or sweating. Remember to reapply regularly. Opt for a texture or formulation you will use consistently. Sensitive skin or rosacea -prone people benefit from zinc oxide-based formulas. “Using extremely high SPFs such as SPF 100+ can create a false sense of security and does not dramatically offer greater protection,” Evans said. “The most important thing is not to abandon sunscreen altogether.”  “The risks associated with chronic UV exposure are very real and very we...

More: Evans wasn’t involved in the report.   “Sunscreen is still one of the most effective tools we have to reduce sunburn, photoaging, and skin cancer risk, including melanoma. SPF 30 to 50 is sufficient for most people, but most dermatologists recommend SPF 50 or higher. “The most important thing is not to abandon sunscreen altogether.

TL;DR: Evans wasn’t involved in the report.   “Sunscreen is still one of the most effective tools we have to reduce sunburn, photoaging, and skin cancer risk, including melanoma.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Eating Avocado and Mango Daily May Improve Blood Pressure in Prediabetes

A recent study suggests a daily avocado-mango combo may offer heart health benefits, such as lowering blood pressure. Nadine Greeff/Stocksy Eating one avocado and 1 cup of mango daily may improve blood vessel function in as little as 8 weeks, according to new research.  The avocado-mango combo was linked to better flow-mediated dilation in both men and women, with lower diastolic blood pressure more pronounced in men. Researchers say the benefits likely come from a mix of fiber, potassium, vitamin C, and heart-healthy fats. Experts stress that overall diet quality matters most, and mango and avocado work best as part of a balanced eating pattern. Eating one avocado and 1 cup of mango daily may help improve heart health in as little as 8 weeks, according to a recent study. Researchers at the Illinois Institute of Technology found that adults with prediabetes who followed this combination experienced improved blood vessel function and reductions in diastolic blood pressure. Participants who followed the avocado and mango diet showed a notable improvement in flow-mediated dilation (FMD), a measure of blood vessel function. Their FMD rose to 6.7%, whereas it fell to 4.6% in the control group, indicating better vascular health in those consuming the fruit combination. Diastolic blood pressure also improved in males. Those in the control group experienced an average increase in central blood pressure of 5 mmHg, while men in the avocado and mango group saw a reduction of around 1.9 mmHg. Importantly, these benefits were observed without changes in calorie intake or body weight. The results were recently published in the Journal of the American Heart Association . The researchers acknowledged that the study was funded by the National Mango Board and the Hass Avocado Board, which is important to consider when interpreting the findings. Avocado-mango combo improves heart health Karen E. Todd , a registered dietitian nutritionist at The Supplement Dietitian, said that while the findings of the new study are promising, it doesn’t mean that a mango-avocado combination is a magic bullet. Todd wasn’t involved in the study. Rather, she said the research highlights how replacing lower-quality foods with nutrient-dense options can improve heart health markers over time. “The study fits with what we already know about diet quality and heart health . In this trial, adults with prediabetes who ate one avocado plus 1 cup of mango daily for 8 weeks had better flow-mediated dilation, a marker of blood vessel function, than the control group,” she told Healthline. “The intervention also increased intake of fruit, fiber , vitamin C, and monounsaturated fat , which are all consistent with a more heart-supportive eating pattern.”  Todd noted that certain nutrients in mangos and avocados likely contributed to the positive results. “Mango likely helps heart health through a combination of vitamin C, potassium , and fiber,” she said. “Vitamin C acts as an antioxidant and supports blood vessel integrity, potassium helps regulate blood pressure, and fiber supports cholesterol and blood sugar control . Together, these nutrients support both vascular function and overall cardiometabolic health .”  Todd said the biggest heart-health advantage of avocados is their unsaturated fat profile, especially monounsaturated fats, along with fiber and potassium. “Replacing saturated fat with unsaturated fat is associated with improved cholesterol levels and lower cardiovascular risk ,” she said. “The added fiber and potassium further support heart health through cholesterol management and blood pressure regulation.” Of course, the study looked at the heart health benefits of eating these two foods together, not each food on its own. “Nutritionally, they complement each other well,” Todd said. “Mango provides vitamin C and carbohydrates , while avocado contributes healthy fats and fiber. Together, they create a more balanced, satisfying option that may support heart health more effectively than either food alone, particularly when they replace processed foods,” she explained. Long-term benefits of eating avocado, mango are unclear A significant finding of this study is that participants who added one avocado and 1 cup of mango to their daily diet showed measurable improvements in blood vessel function, along with reductions in diastolic blood pressure.  Brett A. Sealove , MD, chair of cardiology at Hackensack Meridian Jersey Shore University Medical Center, and associate professor and vice chair of cardiology, Hackensack Meridian School of Medicine, said the new study warrants “serious consideration,” but noted some limitations. Sealove wasn’t involved in the research. “The sample size was relatively small, with 82 participants enrolled and 68 completing the protocol. And the study duration was only 8 weeks, which is brief given that vascular and metabolic remodeling typically occurs over several months,” he told Healthline. “The study was also part...

More: Eating Avocado and Mango Daily May Improve Blood Pressure in Prediabetes. A recent study suggests a daily avocado-mango combo may offer heart health benefits, such as lowering blood pressure. “The study fits with what we already know about diet quality and heart health .

TL;DR: A recent study suggests a daily avocado-mango combo may offer heart health benefits, such as lowering blood pressure.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

The Longer Poop Stays in Your Body, the More It Can Affect Your Health

The time it takes for stool to transit through your body can affect your health. Image Credit: AUDSHULE/Stocksy Research suggests that the amount of time stool spends in your body may affect your overall health.  This may be due to changes in gut microbiomes associated with how quickly or slowly stool moves through the body. An expert explains long-term health issues associated with slow digestion, chronic constipation, and chronic diarrhea.  The amount of time it takes for stool to move through your body may impact your health in more ways than you may think. A 2023 study showed that there may be distinct differences in gut microbiomes depending on whether your stool is fast or slow.  The human gut microbiome is closely linked to overall health. Slow transit times of stool and constipation have shown associations with metabolic and inflammatory conditions, as well as neurological conditions, such as Parkinson’s Disease . This study also looked at previous research on gut transit time. All of the research had the same goal of estimating how long food stays in a person’s colon. The longer it stays, the more time bacteria have to ferment the contents, regulate acidity in the gut, and produce metabolites that can influence the body’s health. The study found that people with faster gut transit times had drastically different microbiomes than those with slower transit times. One approach to estimating the gut transit time was the Bristol Stool Scale . This is a visual tool that classifies stool by consistency. For example, hard, rock-like pellets typically mean a long transit time. Watery, mushy stool often indicates a short transit time.  Transit time can also influence how your body responds to probiotics , as well as supplements and medications that interact with the gut. “The gut is far more than a digestive organ — it is a finely tuned ecosystem whose balance underpins everything from immune function and metabolic health to neurological well-being and cancer risk,” said Ketan Thanki , MD, board certified colorectal surgeon who specializes in benign and malignant disease of the colon, rectum, and anus with the MemorialCare Todd Cancer Institute at Long Beach Medical Center in Long Beach, CA. Healthline spoke with Thanki to learn more about how poop transit time can impact health.  This interview has been lightly edited for length and clarity. How does poop transit time affect gut health? Thanki: Gut transit time is a major determinant of microbiome composition, diversity, and metabolism. Slower colonic transit time is consistently associated with a shift away from beneficial sugar fermentation, which produces health-promoting short-chain fatty acids (SCFAs) and toward protein fermentation that generates potentially harmful byproducts like ammonia and phenols.  The relationship works both ways: transit time shapes which microbial communities thrive, but microbiota and their metabolites — including SCFAs and secondary bile acids — directly influence gut motility. Why does poop transit time lead to inflammatory and metabolic disorders?  Thanki: When transit slows, fermentable carbohydrates become depleted before stool reaches the distal colon, and bacteria switch from fermenting carbohydrates into healthful short-chain fatty acids to fermenting proteins instead ( proteolysis ). This produces metabolites — ammonia, hydrogen sulfide, phenols, indoles, and branched-chain fatty acids — that are directly toxic to colonocytes, damage colonocyte DNA, cause cancer-causing mutations, and promote a leaky gut lining, thereby promoting systemic inflammation. Meanwhile, increased methane production further slows the gut, and increased estrogens in the blood can increase the risk of malignancies like breast cancer and dysregulate levels of other hormones.  SCFA depletion affects systemic metabolism. SCFAs are not just local (colonocyte) fuel. They also signal to the liver to regulate glucose production, and influence adipose tissue metabolism, insulin sensitivity, and secretion of appetite hormones (GLP-1, PYY). When prolonged transit time reduces SCFA production, these regulatory signals are diminished. This is particularly relevant in diabetes and obesity , where gastroparesis and altered transit compound glycemic control problems and energy dysregulation.  Lastly, gut bacteria convert choline and carnitine from meat and eggs into trimethylamine (TMA), which the liver converts to TMAO , a metabolite linked to cardiovascular disease. The paper notes the transit-TMAO link hasn’t been fully characterized yet, but it’s a plausible pathway to worsened heart disease. What are the long-term health risks of slow digestion and constipation? Thanki: Prolonged gut transit time is associated with a broad range of serious long-term health risks: colorectal cancer breast cancer neurological diseases, including Parkinson’s and Alzheimer’s disease cardiovascular and kidney disease metabolic dysregulation contributing t...

More: The Longer Poop Stays in Your Body, the More It Can Affect Your Health. The time it takes for stool to transit through your body can affect your health. How does poop transit time affect gut health?

TL;DR: The time it takes for stool to transit through your body can affect your health.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Aspirin Doesn't Prevent Colorectal Cancer, Review Says. Here's What Helps Instead

A new study demonstrates limited protective benefits for daily aspirin use and colorectal cancer risk. Viktoriya Skorikova/Getty Images Research suggests that daily low dose aspirin doesn’t appear to reduce a person’s risk of colorectal cancer. Frequent aspirin use may increase a person’s risk of bleeding in and around the brain. Experts say you can lower your colorectal cancer risk with lifestyle habits such as eating a plant-based diet, limiting alcohol consumption, and exercising daily. A daily regimen of low dose aspirin probably does not significantly reduce the risk of colorectal cancer but may increase the risk of bleeding in the brain area, according to a large-scale analysis of previous research. Researchers reported that daily aspirin probably does not help in preventing colorectal cancer in the first 15 years of use, although it might have some preventive benefits in the longer term. However, the researchers stated that they are “not confident” in the long-term assessment. They also reported that daily aspirin use may increase deaths from colorectal cancer in the short term but may help reduce deaths after 15 years. Again, the researchers noted they are “not confident” in these conclusions. They did report that daily aspirin use may increase the risk of bleeding outside the skull as well as bleeding in and around the brain. “It is not possible to draw definitive conclusions or outline specific implications for the routine use of aspirin for [colorectal cancer] primary prevention based on the current evidence,” the researchers wrote. “Our findings reveal complex, time‐dependent preventive effects and concerns about potential harms for clinicians and patients to consider.” They published their findings in the Cochrane Database of Systematic Reviews on April 1. They were an update to a previous study they published in February. Ketan Thanki , MD, a colorectal surgeon who specializes in benign and malignant disease of the colon, rectum, and anus at the MemorialCare Todd Cancer Institute at Long Beach Medical Center in California, said this latest report provides cautionary advice for anyone considering an aspirin regimen. “This study demonstrates limited (if any) protective benefit from aspirin on risk of developing colorectal cancer in the general population,” Thanki told Healthline. “With the known potential complications of long-term aspirin use, I would recommend that people don’t take daily aspirin solely with the intent of reducing your risk of developing colorectal cancer.” Low dose aspirin and colorectal cancer risk To reach their findings, the researchers analyzed data from 10 randomized controlled clinical trials. They compared aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) with either no treatment or a different treatment for preventing colorectal cancer or colorectal adenoma in the general population. The studies included more than 120,000 participants. Most of the research was conducted in North America and Europe. Low‐dose aspirin (75-100 mg per day) was typically used, although three studies evaluated higher doses. The researchers said they found that daily aspirin “probably results in little to no difference” in reducing colorectal cancer risks after 5 to 15 years of use. They added that aspirin might slightly reduce colorectal cancer risk after 15 years of use. “I would advise that you only consider daily aspirin for this purpose, either if you have a genetic syndrome that predisposes you to cancer (specifically  Lynch Syndrome ) or have had adenomatous polyps removed during a prior colonoscopy ,” Thanki said. “In those populations, there is  good evidence  that it may decrease risk of cancer and may decrease risk of adenoma recurrence , respectively. Those patients should speak with their doctors.” The researchers also reported that daily aspirin “may increase mortality” from colorectal cancer between 5 and 10 years of use, as well as producing “little to no difference in mortality” between 10 and 15 years, and a possible reduction in mortality after 15 years. They added that aspirin “may result in little to no difference” in colorectal adenoma between 5 and 10 years, but “the evidence is very uncertain.” The researchers also noted that daily aspirin use produced “little to no difference’ in overall serious adverse events, but they said “aspirin does increase the risk of serious extracranial hemorrhage” and “probably increases the risk of hemorrhagic stroke.” The researchers said their findings should raise concerns for medical professionals and patients alike. “The uncertain and delayed potential for benefit must be weighed against a definite harm,” they wrote. “In light of the mixed evidence, clinical practice should continue to center on an individualized assessment and a shared decision‐making process, carefully balancing a patient’s established cardiovascular risk profile against their risk of bleeding,” the researchers wrote. Benefits, risks of daily as...

More: A new study demonstrates limited protective benefits for daily aspirin use and colorectal cancer risk. Experts say you can lower your colorectal cancer risk with lifestyle habits such as eating a plant-based diet, limiting alcohol consumption, and exercising daily. They added that aspirin might slightly reduce colorectal cancer risk after 15 years of use.

TL;DR: A new study demonstrates limited protective benefits for daily aspirin use and colorectal cancer risk.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Egg Coffee Is Percolating on TikTok, but May Pose Serious Health Risks

Egg coffee is going viral on social media, but experts say the trendy drink may come with food safety risks depending on how it is prepared. VU PHAM VAN/Getty Images Egg coffee, made with whipped egg yolks, sugar, and condensed milk, is going viral on social media platforms like TikTok. Experts warn that the drink may increase the risk of Salmonella contamination from raw or undercooked eggs. It can also be high in sugar and saturated fat. Simple swaps can make it safer and healthier. A sweet, creamy twist on your morning cup of coffee is going viral on social media. It’s called egg coffee, and it’s typically made by whisking egg yolks with sugar and condensed milk into a rich, custard-like foam, then layering it over a strong cup of joe or espresso. While the drink is currently trending on TikTok, it isn’t exactly new. Versions of the dessert-like beverage have been around for decades, including Vietnamese egg coffee (cà phê trứng), Swedish egg coffee, and Italian egg-based drinks like zabaglione al caffè. But as the drink gains popularity, some experts are warning that it can carry some serious health risks. Raw eggs in egg coffee may raise salmonella risk One of the biggest concerns about egg coffee is how it’s made. Many recipes call for raw or lightly heated egg yolks, which can carry Salmonella bacteria. “Consuming egg coffee using raw or undercooked yolk does carry a salmonella risk that shouldn’t be ignored,” said Michelle Routhenstein , a preventive cardiology dietitian at Entirely Nourished. While some people may assume that hot coffee is enough to make the drink safe, Routhenstein warns that’s usually not the case. “Hot coffee does not typically reach a safe temperature to cook the egg and reduce the potential risk of salmonella contamination,” Routhenstein said. Salmonella infection can cause symptoms such as diarrhea , fever, and stomach cramps , which may begin anywhere from a few hours to a few days after exposure. While many healthy people recover without treatment, the infection can be more serious for certain groups, including older adults, pregnant people, and those with compromised immune systems. Although the risk of contamination from any single egg is relatively low, food safety experts generally recommend avoiding raw or undercooked eggs when possible. Egg coffee often high in sugar and saturated fat Beyond food safety concerns, egg coffee may also come with nutritional drawbacks. The drink is typically made with sweetened condensed milk and added sugar , which can significantly increase its overall calorie and sugar content. Combined with egg yolks, it can also contribute a notable amount of saturated fat. “We want to be mindful of the saturated fat content that this can add into your day,” Routhenstein said. “Egg yolks and condensed milk can carry several grams of saturated fat, and depending on what else you are eating, this can raise apoB and LDL cholesterol levels.” Higher levels of LDL cholesterol have been linked to an increased risk of heart disease over time. While occasional egg coffee consumption is unlikely to have a major impact on health, regularly drinking high-sugar, high–saturated–fat drinks may not be the best choice for long-term health. Safer ways to try egg coffee at home For those who are curious about egg coffee, there are ways to recreate a similar texture and flavor while reducing potential risks. “To lower salmonella risk, we need to eliminate the raw egg yolk ,” Routhenstein said. One option is to swap in steamed milk or barista-style plant-based alternatives, such as oat milk, to create a creamy, foamy texture without using eggs. These options can mimic the drink’s signature richness while avoiding the food-safety concerns associated with raw or undercooked eggs. Another alternative is aquafaba (the liquid from canned chickpeas), which can be whipped into a stable foam and used as a coffee topping. Using aquafaba “adds an airy cloud effect to your coffee without the salmonella [risk],” Routhenstein said. For those who still want to incorporate eggs, using pasteurized eggs may help reduce the risk of contamination. However, experts still recommend handling them carefully and avoiding recipes that rely on raw or undercooked eggs whenever possible. Healthier substitutions for egg coffee In addition to food safety concerns, making a few ingredient adjustments can help reduce the drink’s overall sugar and saturated fat content. Traditional recipes often rely on sweetened condensed milk and added sugar, which can quickly increase the calorie load. Swapping in lower-sugar alternatives, such as unsweetened or lightly sweetened milk, may help reduce added sugars while still providing a creamy texture. Using lower-fat dairy or plant-based milk can also help reduce saturated fat intake. For example, oat milk or almond milk can offer a similar richness without contributing as much saturated fat as condensed milk. Adjusting portion sizes or treating egg coffee as an...

More: Egg Coffee Is Percolating on TikTok, but May Pose Serious Health Risks. It can also be high in sugar and saturated fat. But as the drink gains popularity, some experts are warning that it can carry some serious health risks.

TL;DR: It can also be high in sugar and saturated fat.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Taking Xanax XR? FDA Recalls Batch Over Effectiveness Concerns

The FDA issued a nationwide recall of Xanax XR for failing to meet dissolution specifications. BSIP/Universal Images Group via Getty Images The FDA has issued a report regarding the voluntary recall of a single lot of Xanax XR. Viatris has recalled 3-milligram tablets in 60-tablet bottles with the lot number 8177156. The company reports that this lot failed to meet dissolution specifications. Experts say this could cause the pills to not be as effective in controlling symptoms. They advise that you continue taking the pills until your doctor can issue a new prescription. A nationwide recall of Xanax has many people wondering whether their anti-anxiety medication has been affected. According to an Enforcement Report issued by the Food and Drug Administration (FDA) , Viatris, Inc., a major pharmaceutical company, has voluntarily recalled a specific lot of Xanax XR (alprazolam extended-release tablets) distributed across the United States. The recall, initiated on March 17, affects 3-milligram tablets packaged in 60-tablet bottles, produced in Ireland and distributed by Viatris Specialty LLC in Morgantown, W.Va.  The decision comes after the product failed to meet dissolution specifications, which are critical for ensuring proper drug release and effectiveness. Patients and healthcare providers are urged to check their medication and contact Viatris or their healthcare professional if they have the affected lot, numbered 8177156, with an expiration date of February 28, 2027. No safety concerns over affected Xanax XR pills The issue was identified through quality control testing, which revealed that the tablets failed to meet the FDA dissolution specifications .  Dissolution testing measures how quickly and efficiently the active ingredient is released from the tablet into the body. As noted in the Enforcement Report, the formulation of the drug being recalled is Xanax XR, a medication commonly prescribed for the treatment of anxiety and panic disorders. This extended-release formulation is designed to release the medication gradually over time, providing more consistent symptom control. Aleksey Aronov , AGPCNP-BC, a board certified adult geriatric primary care nurse practitioner and the founder and CEO of VIPs IV, told Healthline that if the pill does not meet dissolution specifications, it may not break down as it should in the body, which could result in the medicine not working properly. “When a pill does not dissolve the right way, the body may not absorb the correct amount of the medicine, which may result in not treating anxiety or panic symptoms appropriately,” he said. “Pills that fail to dissolve essentially may not be effective.” The Enforcement Report further notes that the recall is classified by the FDA as a Class II recall. Class II indicates that the use of this medication could cause “temporary or medically reversible adverse health consequences,” however, there is little risk of serious adverse health consequences, according to the agency. Aronov clarified this description further by explaining that failed dissolution is not a safety hazard, nor will the drug cause harm to your body. “It is just a quality control issue that may result in the patient not benefiting from the medicine when they take it,” he said. What should you do if you take Xanax XR? People taking Xanax should speak with their doctor about getting a replacement prescription, Aronov said. “Patients should not abruptly stop taking Xanax because this medicine requires a very gradual taper in order to prevent withdrawal symptoms,” he said. Roger Flugel , chief scientific officer for Neurogan Health, emphasized that patients using this drug “shouldn’t panic.” Firstly, it’s only the 3-milligram tablets of Xanax XR in 60-tablet bottles identified by the lot number 8177156 that are affected, he said. “It’s important that you know the lot number before anything else, and see to it that you take the necessary steps,” said Flugel. Even if you have this lot number, he explained that you aren’t in any imminent danger since any health effects are temporary and reversible. “My advice is that you shouldn’t abruptly stop taking it, even when the lot number [of the] medication matches the one above, as that can be riskier,” Flugel said. Instead, continue to take your medication as directed and speak with your doctor right away about your concerns. No press release has been issued by the FDA for this recall, and the recall remains ongoing as of the latest available data from April 8, 2026. Consumers and healthcare professionals can stay informed by monitoring the FDA website or contacting Viatris directly.

More: Taking Xanax XR? Class II indicates that the use of this medication could cause “temporary or medically reversible adverse health consequences,” however, there is little risk of serious adverse health consequences, according to the agency. Even if you have this lot number, he explained that you aren’t in any imminent danger since any health effects are temporary and reversible.

TL;DR: Class II indicates that the use of this medication could cause “temporary or medically reversible adverse health consequences,” however, there is little risk of serious adverse health consequences, according to the agency.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Mounjaro, Zepbound Lower Death Risk for People With Serious Heart Conditions

GLP-1 drugs containing tirzepatide significantly reduce cardiovascular risks in people with serious heart conditions. Indranil MUKHERJEE / AFP via Getty Images GLP-1 weight loss medications containing tirzepatide (Mounjaro, Zepbound) can reduce heart-related health risks for people with serious heart conditions, according to new research. Experts say the heart health benefits are produced by the drugs’ ability to help people lose weight and control blood sugar levels. People using these medications should also maintain a healthy lifestyle, including daily exercise and a balanced diet, to maintain overall health. Weight loss medications containing the active ingredient tirzepatide significantly reduce cardiovascular risks in people with serious heart conditions, according to new research. The results of two studies indicate that GLP-1 drugs containing tirzepatide (i.e., Mounjaro , Zepbound ) may lower heart-related risks for people undergoing percutaneous coronary intervention (PCI) and those with obesity undergoing transcatheter aortic valve replacement (TAVR) . The researchers presented their findings at the SCAI 2026 Scientific Sessions & CAIC-ACCI Summit in Montreal from April 23–25. The two studies have not yet been published in a peer-reviewed scientific journal. Tirzepatide medications are usually prescribed to help treat type 2 diabetes . According to a news release for the two studies, tirzepatide’s ability to manage blood sugar levels and promote weight loss delivers “meaningful cardiovascular benefits.” While prior research has established these benefits, their impacts on patients undergoing interventional heart procedures have not yet been extensively evaluated. Notably, the researchers found a 62% lower risk of death among participants receiving tirzepatide who underwent a PCI procedure. “GLP-1 agonists represent an important evolution in cardiometabolic care,” said SCAI President Srihari Naidu , MD, an interventional cardiologist, in the news release. “Clinicians already recognize the benefits of glycemic control and weight reduction, but we are now beginning to understand how these therapies can improve outcomes in patients undergoing transcatheter cardiovascular interventions.” Experts not involved in the new studies say the research supports earlier studies on the cardiovascular benefits of weight loss drugs. “These findings are consistent with what we are seeing broadly that medications like tirzepatide are not just weight loss drugs but have meaningful cardiometabolic benefits,” said Kevin Shah , MD, a cardiologist and the program director of Heart Failure Outreach at MemorialCare Heart & Vascular Institute at the Long Beach Medical Center. “We do need prospective studies to validate the findings from these analyses.” Tirzepatide lowers stroke, heart attack risk In the first study , researchers from John H. Stroger Jr. Hospital of Cook County, Chicago, IL, sifted through the TriNetX database . They identified adult participants with type 2 diabetes who received GLP-1 drugs containing tirzepatide or older medications with the active ingredient dulaglutide at the time of their PCI procedure. The researchers did not compare tirzepatide drugs with medications that contain the active ingredient semaglutide, such as Ozempic and Wegovy . In all, the researchers examined the medical records of 1,281 study participants. One month after PCI, they reported that the participants who used tirzepatide drugs experienced lower rates of major adverse cardiovascular events, such as: acute myocardial infarction heart failure ventricular arrhythmias They noted there was no difference in rates of stroke among participants using tirzepatide drugs and those using dulaglutide medications. One year after PCI, researchers observed reductions in MACE, myocardial infarction, and heart failure exacerbation, remaining consistent after one year. There were also further reductions in mortality, stroke, and cardiac arrest at one year. “The study adds on additional data to what we’ve already previously known about GLP-1 containing agents: these drugs hope to reduce risk for cardiovascular complications from obesity,” said Yu-Ming Ni , MD, a cardiologist and lipidologist at MemorialCare Heart and Vascular Institute at Orange Coast Medical Center in Fountain Valley, CA. Ni wasn’t involved in the study. “This patient population in this study is automatically higher risk because they need an intervention for their conditions,” Ni told Healthline. “Consequently, seeing a reduction in risk of cardiovascular events is promising, albeit not surprising.” Jackie DesJardin , MD, a cardiologist and an assistant clinical professor of medicine at the University of California San Francisco’s Division of Cardiology, cautioned that there may be more to these results than simply the medications. DesJardin wasn’t involved in the study. “The dramatic reductions seen here, more than 50% lower heart attack risk within just one ...

More: Mounjaro, Zepbound Lower Death Risk for People With Serious Heart Conditions. GLP-1 drugs containing tirzepatide significantly reduce cardiovascular risks in people with serious heart conditions. Experts say the heart health benefits are produced by the drugs’ ability to help people lose weight and control blood sugar levels.

TL;DR: GLP-1 drugs containing tirzepatide significantly reduce cardiovascular risks in people with serious heart conditions.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Trump Reclassifies State-Licensed Medical Cannabis, but It’s Not Legal Just Yet

Flowers, also known as buds, grow at the top of a mature marijuana plant on a farm owned and operated by Qualla Enterprises, LLC in Cherokee, NC. Image credit: Charlotte Observer/Getty Images An executive order signed by the Trump administration reclassifies medical cannabis as a less dangerous drug. Although this does not legalize cannabis under federal law, it marks a significant shift in policy. The change will provide significant tax breaks for businesses that sell cannabis and ease barriers for researchers who possess the drug in order to study it. Acting Attorney General Todd Blanche signed an order on April 23 to reclassify state-licensed medical marijuana as a less dangerous drug. This major shift in policy does not legalize cannabis for recreational or medical use under federal law. However, reclassifying cannabis as a Schedule III drug changes how it’s regulated. For instance, licensed medical cannabis businesses will receive tax breaks. Researchers studying the drug’s effects will run into fewer roadblocks. The move aligns with advocates who’ve long said the substance shouldn’t be held in the same regard as drugs like heroin by the federal government. Trump told the press that he had received several phone calls pleading for restrictions to be lifted. In December, he told his administration to move quickly on reclassifying cannabis.  “The Department of Justice is delivering on President Trump’s promise to expand Americans’ access to medical treatment options,” Blanche said in a statement issued by the U.S. Department of Justice (DOJ). “This rescheduling action allows for research on the safety and efficacy of this substance, ultimately providing patients with better care and doctors with more reliable information.” Reclassification of marijuana doesn’t mean legalization The move to reclassify marijuana focuses on medical cannabis and products approved by the Food and Drug Administration (FDA). The Trump administration has scheduled a June hearing that will provide a pathway for evaluating broader changes to cannabis status under federal law. For now, cannabis remains illegal at the federal level. Most states allow recreational use, medical use, or both. Only 2 states — Idaho and Kansas — do not have any legal cannabis programs whatsoever. This means that anyone researching or selling cannabis in a state where it was legal was subject to federal prosecution.   Currently, cannabis has been classified as a Schedule I drug in the same class as LSD and heroin, which have significant potential for abuse and “no currently accepted medical use.”  Reclassifying marijuana as a Schedule III drug puts it in the same bracket as Tylenol mixed with codeine : Medically beneficial drugs with low potential for abuse. Although this change will not be welcomed in all quarters, public sentiment is broadly aligned. A 2025 Gallup poll , for instance, showed that support in the United States for cannabis legalization had almost doubled from 36% in 2005 to 64%.  What does reclassification mean for the cannabis industry? Currently, businesses in states that allow medical or recreational cannabis use face significant headaches. While their business may be entirely legal in their state, it is illegal at the federal level, making banking and tax compliance challenging. This new legal change will make a significant difference. Terry Mendez , CEO of Safe Harbor Financial, a company that works with the cannabis industry, called the order “the most significant federal action on cannabis policy in more than 50 years.” From a business standpoint, changes in how taxes are collected will have the greatest impact. Now, for the first time, state-licensed medical cannabis companies will be able to deduct business expenses on their federal taxes. On the same point, Anthony Coniglio , CEO at NewLake Capital Partners, Inc , said that this “is a material shift not only for operators and patients, but also for investors, lenders, and real estate partners evaluating the cannabis sector.”  Similarly, Nico Richardson, CEO of Texas Original , a provider of medical cannabis, told Healthline that the move is “a significant step for Texans who will benefit from easier access to needed medicine.” A new dawn for cannabis research? Industry aside, scientists will benefit from this shift in cannabis regulation. With easier access to the drug and a significant reduction in red tape, it will be much easier (and cheaper) to investigate cannabis for the treatment of health conditions. Sasha Kalcheff-Korn is the executive director of Realm of Caring, a nonprofit that provides information about cannabinoid therapies, conducts research, and awards research grants. Realm of Caring is currently partnering with the Johns Hopkins Behavioral Pharmacology Research Unit to conduct a national medicinal cannabis use registry. “Rescheduling will make it easier to complete this research and conduct future studies,” Kalcheff-Korn told Healthline. “Helping build th...

More: Trump Reclassifies State-Licensed Medical Cannabis, but It’s Not Legal Just Yet. Most states allow recreational use, medical use, or both. With easier access to the drug and a significant reduction in red tape, it will be much easier (and cheaper) to investigate cannabis for the treatment of health conditions.

TL;DR: With easier access to the drug and a significant reduction in red tape, it will be much easier (and cheaper) to investigate cannabis for the treatment of health conditions.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

A Simple Sugar in Ultra-Processed Foods May Drive Obesity, Metabolic Disease

Research shows that fructose, especially in ultra-processed foods, may increase the risk of metabolic diseases. Image Credit: Ivan Solis/Stocksy A recent study has shown that fructose plays a role in driving disease. The research shows that the effects fructose can have on the body may be associated with metabolic syndrome. Understanding the effects of fructose on the body may help develop new strategies to prevent and treat metabolic diseases. Fructose is a simple sugar that is found both naturally, in honey and fruits, and in sweeteners like high-fructose corn syrup and sucrose (table sugar). A recent review published in Nature Metabolism highlights the role fructose plays in driving disease. This is separate from its role as a source of calories. Consumption of  fructose  has grown significantly over the past  few centuries,  driven by the increased use of sweeteners in the average diet. Fructose can be problematic because it has twice the sweetness of glucose . This may lead to increased cravings for more fructose-containing foods and drinks. “Fructose found in these processed forms is not handled the same way as regular blood sugar,” said Michelle Routhenstein , preventive cardiology dietitian at EntirelyNourished, who wasn’t involved in the study.  “When it is consumed, it goes to the liver, where it easily turns into fat, which can build up in the liver and around the organs and contribute to conditions like fatty liver and metabolic syndrome,” she told Healthline. Effects of fructose on metabolic health Unlike glucose, fructose has unique metabolic effects. These effects may help contribute to obesity and related conditions. “The emerging body of research suggests that fructose is not metabolically identical to all other carbohydrates, especially when it is consumed in excess through sugar-sweetened beverages and ultra-processed foods,” said Serena Poon , certified nutritionist & longevity wellness advisor. Poon wasn’t involved in the study.  “Excess calories still matter, but fructose may affect metabolism differently than other sugars, particularly in the liver … In my view, this supports a more nuanced conversation because it is not just about sugar in the abstract, but also about the form, dose, and dietary context in which fructose is consumed,” Poon told Healthline. The review highlights how the metabolism of fructose bypasses key regulatory steps in the energy processing pathways. This can have various effects, including: increased fat synthesis depletion of cellular energy production of compounds associated with metabolic syndrome Metabolic syndrome is a group of conditions that includes obesity , insulin resistance , and cardiovascular risk . Other health impacts of fructose The review points out that fructose metabolism can contribute to more than metabolic syndrome. It has associations with: metabolic dysfunction-associated steatotic liver disease (MASLD) hypertension (high blood pressure) kidney disease gout cancer growth, including breast , lung , pancreatic , and prostate “High intakes of ultra-processed or concentrated fructose can also raise uric acid and increase oxidative stress ,” said Routhenstein. Poon echoed these remarks. “There is also emerging evidence that high fructose exposure may affect appetite regulation , satiety signaling, and gut barrier function, especially when intake is chronic and concentrated in liquid form,” she said. “That said, the strongest concerns are generally tied to patterns of habitual excess intake rather than to modest amounts consumed in whole foods.”  Poon cautioned that people should “not turn this into a fear-based conversation about all fructose-containing foods. Whole fruit can absolutely fit into a healthy dietary pattern and is consistently viewed differently from added sugars in the research.”  Routhenstein agreed. “The study is really about large amounts of added fructose (like in sodas and ultra‑processed foods), which overload the liver and drive fat buildup and metabolic problems, not the smaller amounts naturally present in whole fruit,” she said. “Whole fruits don’t contain excessive amounts of fructose, and they come packaged with fiber and beneficial plant compounds. These beneficial compounds found in fruit help slow sugar absorption, and help reduce inflammation around the liver and support cholesterol-lowering and metabolic functions,” Routhenstein continued. What foods contain fructose? Fructose is naturally found in foods like fruits and honey. The sweeteners sucrose and high fructose corn syrup are often found in: many baked goods soft drinks sweet teas fruit punches candy processed sauces salad dressings flavored yogurt Tips to limit fructose intake To limit your intake of fructose, Poon recommended reading food and beverage nutrition labels. “Fructose often appears through ingredients such as high-fructose corn syrup, cane sugar, fruit juice concentrate, and other added sweeteners,” she said.  Routhenstein ...

More: A Simple Sugar in Ultra-Processed Foods May Drive Obesity, Metabolic Disease. Research shows that fructose, especially in ultra-processed foods, may increase the risk of metabolic diseases. The research shows that the effects fructose can have on the body may be associated with metabolic syndrome.

TL;DR: Research shows that fructose, especially in ultra-processed foods, may increase the risk of metabolic diseases.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Want to Recover Like an Olympian? Allyson Felix Says ‘Fill Your Cup First’

Track and field star Allyson Felix shares rest and recovery tips and explains why motherhood inspired her to advocate for paid leave. Allyson Felix, mom of two and the most decorated track and field athlete in U.S. history, understands the importance of rest and recovery. Photography courtesy of Allyson Felix When it comes to national policies around paid sick or family leave, the United States falls short compared to other developed countries. Around 28 million Americans lack access to paid sick time, which disproportionately affects low-income workers and their families, particularly caregivers. A recent survey from Theraflu and Wakefield Research of more than 1,000 employed U.S. adults who care for someone in their household found that 80% of respondents couldn’t afford to take a sick day. More than half of respondents said they worked while sick because they needed the income, while 28% said that taking a sick day could put their job at risk. Working parents are often obligated to continue their responsibilities even when they’re sick. Mothers are more likely than fathers to bear the brunt of this responsibility , even in the most egalitarian households. Without paid sick leave, burnout is inevitable — whether you’re a caregiver or not. If left unchecked, burnout can lead to serious health issues like heart disease and type 2 diabetes . That’s why track and field icon Allyson Felix is on a mission to help make paid sick time a fundamental right rather than a privilege.  The five-time U.S. Olympian partnered with Theraflu to raise awareness for The Right to Rest & Recover Fund , which has offered microgrants to families that help offset lost income from unpaid sick days. The Fund has distributed more than $1 million in microgrants since 2021. As a mom of two, Felix knows firsthand how physically and emotionally taxing it can be to care for young children when you’re unwell. The elite sprinter specializing in the 200m, 400m, and relay events understands the importance of rest and recovery for the body and mind. At 40, her recent announcement to make a comeback for the 2028 Olympic Games in Los Angeles is a testament to this. As the most decorated American track and field athlete in history — with 11 Olympic medals across five Games and a three-time world champion — Felix has her heart set on another goal: Paid sick leave for all. “I don’t think it’s a conversation that we’re having enough of,” Felix told Healthline. “I love that Theraflu is doing something about it for people who are experiencing this hardship.” Rest and recovery prevent burnout Regardless of your parenting or caregiving status or even your fitness level, everyone benefits from rest and recovery — and from sick days when you need them. Clarinda Hougen , MD, primary care sports medicine specialist at Cedars-Sinai Orthopaedics in Los Angeles, CA, said that from an exercise science standpoint, rest and recovery are fundamental. “When we exercise, we place stress on our muscles, tendons, and other tissues,” she told Healthline. “Healing the microtears that occur in muscle tissues during exercise results in muscle hypertrophy and can only occur during periods of rest. In other words, strength gains and improved endurance occur during recovery rather than during the exercise itself.” Hougen shared a few tips to prioritize rest and recovery: Get at least 7 hours of sleep per night. Build 1–2 rest days into your weekly exercise regimen. Practice “ active recovery ” (i.e., light walking , cycling, yoga , or other low intensity activities immediately after a high intensity workout). Eat a nutritious diet including protein and carbohydrates. “Athletes who participate in a variety of different activities that involve different types of movement are less likely to experience injury,” she said. I just try to do the best that I can each day Allyson Felix Quality sleep and self-care promote recovery Hougen explained that inadequate sleep can negatively impact performance and raise the risk of injury in athletes and non-athletes. “Rest and recovery should absolutely be considered a core pillar of every individual’s wellness regimen,” Hougen said. “If rest periods are inadequate over many weeks, the body is not able to fully repair and heal damaged tissues, and overtraining syndrome may develop,” she said. “When this occurs, athletes may feel decreased enjoyment in their sport and increased perceived exertion during activity.” From a physical standpoint, recovery practices might include intentional rest, sleep, and other forms of lighter exercise. Taking time to rest can also help reduce stress and improve mood , fostering mental resilience , Hogen said. Felix echoed this sentiment, emphasizing that it’s important to recognize when you need rest and recovery and to carve out time and space for it. “I just try to do the best that I can each day by being intentional and planning out how I’m going to take care of my body,” Felix said. Allyson Felix...

More: If left unchecked, burnout can lead to serious health issues like heart disease and type 2 diabetes . “When we exercise, we place stress on our muscles, tendons, and other tissues,” she told Healthline. Taking time to rest can also help reduce stress and improve mood , fostering mental resilience , Hogen said.

TL;DR: If left unchecked, burnout can lead to serious health issues like heart disease and type 2 diabetes .

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Trump Administration Aims to Fast-Track Psychedelic Therapies for PTSD

The Trump administration has directed the FDA to fast-track psychedelic therapies like ibogaine to treat PTSD and other mental health disorders. farmer images/Getty Images A sweeping executive order aims to fast-track psychedelic therapies, putting drugs like ibogaine in the national spotlight. The policy expands research funding, accelerates FDA review pathways, and opens access routes for patients with serious mental illness. The executive order explicitly calls out ibogaine therapy, despite limited research and serious questions about its safety profile . The move coincides with Trump’s recent call to reclassify medical cannabis as a less dangerous drug, marking major shifts in national policy around controlled substances. President Trump signed an executive order aimed at expanding research and improving access to psychedelic drug therapies. The April 18 order also aims to streamline and expedite the Food and Drug Administration’s approval process for certain high-priority treatments. The Trump administration has touted the executive order as an important step toward addressing the nation’s mental health crisis , especially among U.S. veterans, who bear an outsized share of that burden. A diverse coalition, including psychedelic research organizations, medical professionals, veterans groups, and podcaster Joe Rogan, has publicly celebrated the decision. The order also allocates $50 million to support state-level psychedelic research. The shift in policy coincides with Trump’s recent move to reclassify medical cannabis as a less dangerous drug. Matthew Johnson , PhD, professor of psychiatry and behavioral sciences at Johns Hopkins University, called the decision “welcome news,” adding that it is “building upon decades of science.” Psychedelics are a class of drugs that act on the body’s serotonin system. They can produce well-known effects, including changes to visual perception, hallucinations , an altered sense of self, and feelings of insight or connection. Primary examples of psychedelics include LSD , psilocybin (“magic mushrooms”) , and DMT . Over the past several decades, research into psychedelic therapies has moved from the counterculture fringes to the White House. Today, psychedelics are actively being studied for a number of mental health conditions, including substance misuse , alcohol use disorder , depression , anxiety , and post-traumatic stress disorder (PTSD) . The President’s executive order is one of the boldest federal actions on psychedelic drugs to date. However, it is also being met with caution by some experts who expressed concern that expedited FDA approval of experimental therapies could be harmful to patients. “It’s important to explore the use of psychedelics to treat [hard-to-treat] disorders like PTSD, that’s completely reasonable,” said Richard Friedman , MD, psychiatrist and director of the Psychopharmacology Clinic at Weill Cornell Medicine. “What we don’t want to do is speed up the testing and evaluation of drugs if it means that we’re giving short shrift to the rigorous analysis of safety,” Friedman told Healthline. Targeting suicide, serious mental illness with psychedelics Trump’s executive order is intended to target “the burden of suicide and serious mental illness rates in Ameica” through a number of levers involving research, access, and FDA review. Here are the main points: The executive order directs the FDA to provide Commissioner’s National Priority Vouchers to eligible psychedelic therapies that have received Breakthrough Therapy designation for serious mental illnesses.  Breakthrough Therapy is an expanded Fast Track designation intended to expedite the development of drugs that have shown early clinical evidence of substantial improvement over existing therapies. The voucher program is designed to shorten the FDA’s review period for such drugs; a process that might typically take six months or more could be reduced to 1 or 2 months.  Taken together, these two programs could significantly accelerate the development and approval of high-priority psychedelic therapies with promising clinical data. Next, the order seeks to expand psychedelic research by allocating $50 million through the Advanced Research Projects Agency for Health (ARPA-H) to match state investments in psychedelic research programs. It also requires collaboration among the FDA, the Department of Health and Human Services (HHS), the Department of Veterans Affairs, and the private sector to increase interest and participation in psychedelic research clinical trials. For patients, the executive order emphasizes the use of the Right to Try Act . This federal law allows eligible patients with life-threatening conditions to access investigational drugs outside of clinical trials. A White House fact sheet explicitly includes experimental psychedelic therapies within the scope of the Right to Try Act, so long as they “have met basic safety requirements.” While psychedelic therapy drugs, including...

More: The Trump administration has directed the FDA to fast-track psychedelic therapies like ibogaine to treat PTSD and other mental health disorders. farmer images/Getty Images A sweeping executive order aims to fast-track psychedelic therapies, putting drugs like ibogaine in the national spotlight.

TL;DR: The Trump administration has directed the FDA to fast-track psychedelic therapies like ibogaine to treat PTSD and other mental health disorders.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Mounjaro May Lead to Greater Lean Body Mass Loss than Ozempic. Here's Why

Research shows that Ozempic may preserve lean body mass better than Mounjaro. Image Credit: Iuliia Burmistrova/Getty Images A recent study found that semaglutide medications, such as Ozempic, may better preserve lean body mass than tirzepatide medications, such as Mounjaro.  This may be due in part to tirzepatide leading to more significant weight loss.  The findings show that maintaining a strength-training routine may help reduce muscle loss when using GLP-1s.  GLP-1 drugs have exploded in popularity due to their ability to promote significant weight loss. This class of medications has helped transform the way healthcare professionals treat obesity.  Semaglutide medications, such as Ozempic or Wegovy , and tirzepatide medications, such as Mounjaro and Zepbound , are the most popular GLP-1 drugs for weight loss.  A study recently published in medRxiv has shown that while tirzepatide appears to lead to greater weight loss, there may be a trade-off of a higher loss of lean body mass than semaglutide. Lean body mass includes muscle, connective tissue, and other essential components that support metabolism, strength, and overall physical function.  This study is a preprint and has not yet been peer-reviewed in a scientific journal, but here’s what the researchers found. Mounjaro led to 2% higher loss of lean body mass The study examined 7,965 individuals who were newly initiating a GLP-1 medication . Of these, 6,196 were using semaglutide , and 1,769 were using tirzepatide . The researchers measured each participant’s lean body mass before and after beginning their first prescription of either semaglutide or tirzepatide. They found that those on tirzepatide consistently showed a greater loss of lean body mass. People on tirzepatide lost about 1.1% more lean body mass than those using semaglutide in the first 3 months of using the medications. This increased to 2% more lean body mass loss by 12 months. “This finding is not entirely surprising. Tirzepatide is generally more potent than semaglutide, and with greater overall weight loss, you often see a higher degree of lean mass loss as well,” said Jeffrey Lee , MD, double board certified plastic surgeon and founder of JL Plastic Surgery, who also prescribes GLP-1s. Lee was not involved in the study. “In other words, the more aggressive the weight loss, the greater the likelihood that some of that loss includes muscle, not just fat,” Lee told Healthline. Why does muscle loss matter? With greater weight loss often comes greater muscle loss. This is important because muscle, especially skeletal muscle, helps control mobility and strength, energy expenditure, and metabolism. Excessive muscle loss affects your overall health. It can lead to fatigue, reduced physical performance, and increased risk of injury. Who is at higher risk of muscle loss from GLP-1s? The study highlights certain factors that may increase your risk of losing more lean body mass, including: higher doses and longer treatment duration lower tolerance for exercise during treatment pre-existing musculoskeletal conditions Around 10% of people using trizepatide achieved a 20% weight reduction and a 5% reduction in lean body mass. This type of loss was observed in only about 7% of those using semaglutide.  How can you manage lean body mass loss with GLP-1s? The study emphasizes the importance of physical activity while taking GLP-1s. Lee agreed. “Exercise (particularly strength training ) plays a critical role in preserving lean muscle mass while on GLP-1 medications,” he said. “I emphasize to my patients that both adequate protein intake and exercise are essential for preserving muscle. Both aerobic exercise and resistance training are highly beneficial,” added Mir Ali , MD, bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA. Ali wasn’t involved in the study.  Lee noted that resistance training signals the body to maintain muscle, even in a calorie deficit , and should be a core part of any weight loss plan using GLP-1 drugs.  Ali emphasized that adequate protein intake is also an important factor in supporting muscle preservation. “Just as important is the pace of weight loss — slower, more gradual weight reduction tends to better preserve lean mass compared to rapid weight loss. This is why careful dose titration and ongoing monitoring are key when using GLP-1s,” Ali told Healthline.

More: Mounjaro May Lead to Greater Lean Body Mass Loss than Ozempic. With greater weight loss often comes greater muscle loss. Who is at higher risk of muscle loss from GLP-1s?

TL;DR: With greater weight loss often comes greater muscle loss.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Your Fitness Level After 40 Can Add Years to Your Life and Boost Health

A recent study found that your midlife fitness can affect your life span and health span. Image Credit: Emilija Manevska/Getty Images Recent research has shown that adults with higher levels of midlife cardiorespiratory fitness may live longer, healthier lives. The study found that people with higher fitness levels not only lived longer but also developed chronic conditions later than those with lower fitness levels. Experts share tips to help improve your cardiorespiratory fitness. Regular physical activity and fitness levels are important for overall health and well-being. According to a recent study, your level of cardiorespiratory fitness in midlife can not only help determine how long you live, but also how many of those years you spend in good health.  Cardiorespiratory fitness refers to how well your heart and lungs supply oxygen during physical activity.  The study showed that adults with higher midlife cardiorespiratory fitness lived longer, developed fewer chronic diseases, and spent more years free from serious illness than those with lower fitness. The results were recently published in the JACC , the flagship journal of the American College of Cardiology. “People with higher fitness may also have had other health advantages, such as better diet, less smoking, or more consistent access to care,” said Robert Glatter , MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hospital in New York City, and assistant professor of emergency medicine at Zucker School of Medicine at Hofstra/Northwell. Glatter wasn’t involved in the study. “The findings are very much in line with decades of research showing that cardiorespiratory fitness is one of the strongest markers of long-term health,” Glatter told Healthline. Higher midlife fitness prolongs life span by 3% Life span refers to how long you live. Health span refers to how long you live free of any major chronic diseases.  The study results showed that cardiorespiratory fitness can not only affect life span but also health span.  It followed 24,576 adults, 25% of whom were females, from the Cooper Center Longitudinal Study (CCLS). The participants were healthy individuals ages 65 or younger. The researchers later tracked their health outcomes using Medicare data.  Participants’ fitness was measured before age 65 using a treadmill test. During the study, the researchers used Medicare data to identify major chronic diseases for each participant.  They defined major diseases using 11 chronic conditions: heart failure ischemic heart disease stroke chronic obstructive pulmonary disease (COPD) chronic kidney disease (CKD) diabetes Alzheimer’s disease and dementia colorectal cancer lung cancer breast cancer (females) prostate cancer (males) The results showed that males with higher fitness levels had a 2% longer health span, 9% fewer diseases, and a 3% longer life span than those with lower fitness levels. The results showed similar patterns among females. “This study confirms our understanding of cardiorespiratory fitness as a marker of future health outcomes, and should encourage all of us to make physical activity a part of our daily lives,” Cheng-Han Chen , MD, board certified interventional cardiologist and medical director of the Structural Heart Program at MemorialCare Saddleback Medical Center in Laguna Hills, CA, told Healthline. Chen wasn’t involved in the study. Mary Greene , MD, a board certified cardiologist with Manhattan Cardiology in NYC, wasn’t involved in the study but noted a “dose-response benefit” in the findings. “Even modest increases in cardiovascular fitness can lead to a 10–25% improvement in survival,” said Greene. Still, Glatter said the findings should be interpreted with caution. “The study does not prove cause and effect. It was an observational study, so it cannot prove that higher fitness directly caused the better outcomes,” he said. Why is cardiorespiratory fitness important? Strong cardiorespiratory fitness can help lower your risk of heart disease. Improving your cardiorespiratory fitness can also:  decrease cardiovascular and all-cause mortality decrease the incidence of heart failure decrease the risk of cardiometabolic diseases (i.e., diabetes, high blood pressure, and kidney disease) Tips to improve cardiorespiratory fitness The main way to improve your cardiorespiratory fitness is to maintain regular physical activity.  “The encouraging answer is that improvement does not require becoming an athlete,” said Glatter. “For most adults, the target is at least 150 minutes of moderate-intensity aerobic activity per week, or 75 minutes of vigorous activity, plus muscle-strengthening exercise at least twice a week.” Examples include: brisk walking cycling jogging swimming water aerobics “A useful rule of thumb is this: during moderate exercise, you can talk but not sing; during vigorous exercise, you can only say a few words before needing a breath,” Glatter said.  Chen agreed. “I would encour...

More: Your Fitness Level After 40 Can Add Years to Your Life and Boost Health. A recent study found that your midlife fitness can affect your life span and health span. Strong cardiorespiratory fitness can help lower your risk of heart disease.

TL;DR: A recent study found that your midlife fitness can affect your life span and health span.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Coffee May Alter Gut Microbiome to Reduce Stress (Yes, Even Decaf)

Coffee, even without caffeine, can reduce stress, improve learning, and boost mood by influencing your gut-brain axis. Oleg Breslavtsev/Getty Images New research suggests both caffeinated and decaffeinated coffee can improve mood and reduce stress by influencing the gut–brain axis. Coffee may alter the gut microbiome, increasing bacteria linked to digestion, immunity, and emotional regulation. Decaf coffee was associated with improved learning and memory, while caffeinated coffee enhanced attention and reduced anxiety and inflammation. Experts say coffee’s polyphenols and other compounds may support mental well-being by lowering inflammation and strengthening communication between the gut and brain. Your morning cup of coffee may be more than just an energizing ritual. New research from APC Microbiome Ireland suggests that both caffeinated and decaffeinated coffee can improve mood and reduce stress by acting on the gut–brain axis. Researchers analyzed 62 adults, including 31 regular coffee drinkers and 31 non-drinkers, using psychological assessments, diet tracking, and stool and urine samples to examine changes in the gut microbiome and mood.  Coffee drinkers, defined as those consuming 3 to 5 cups daily, first abstained for two weeks, which led to notable shifts in gut metabolite profiles. When coffee was reintroduced in a blinded trial, half consumed caffeinated and half decaffeinated. Both groups reported reduced stress, depression, and impulsivity, suggesting benefits beyond caffeine.  Researchers also observed increases in specific gut bacteria linked to digestion and immune function.  Decaffeinated coffee was associated with improved learning and memory, while caffeinated coffee was linked to reduced anxiety, better attention, and lower inflammation, highlighting distinct but complementary effects. How coffee affects the gut-brain axis  Coco Pierrel , is a certified integrative nutritionist and founder of Eat Shed Glow, who was not involved in the research. She told Healthline that this study is the first to confirm what gut health specialists have seen in clinical practice for years: that coffee is a functional beverage.  “Coffee feeds your gut microbes through plant compounds called polyphenols and fiber-like molecules called melanoidins,” Pierrel explained.  “Your gut bacteria ferment these into short-chain fatty acids, which send signals directly to the brain through the vagus nerve.”  Pierrel recommended thinking of your gut as a second brain that is in constant communication with your first brain, and coffee is one of the loudest messages you send it every morning.  “Caffeine blocks adenosine receptors in the brain to sharpen alertness, while stimulating gastric acid and motility in the gut,” she explained.  “Coffee is one of the few daily habits that synchronizes your metabolism with your mental clarity, which is exactly what makes it such a powerful player on the gut-brain axis.”  Caffeinated and decaffeinated coffee have health benefits People often associate the mental benefits of coffee with caffeine. However, this study shows that when it comes to lowering stress, boosting learning, and improving memory, decaf coffee has merit too.  “The polyphenols in coffee, whether caffeinated or decaffeinated, lower inflammation, and chronic low-grade inflammation is one of the most underrated drivers of low mood and anxiety ,” Pierrel pointed out.  “Those same polyphenols get fermented by gut bacteria into short-chain fatty acids like butyrate, which strengthens the gut barrier and quiets inflammatory signaling to the brain.”  Coffee polyphenols also help regulate the HPA axis, the body’s central stress response system, which is likely why both caffeinated and decaf drinkers in this study reported feeling less stressed.  “A healthy brain is often the byproduct of a healthy gut ,” Pierrel said.  Caffeine can boost mental health Still, the study noted some differences between caffeinated and decaffeinated coffee. Caffeinated coffee, in particular, was associated with reduced anxiety and improved vigilance and attention. Why is this the case?  “Caffeine blocks adenosine, the molecule that tells your brain it is tired, which is why you feel sharper within 30 minutes of your first cup,” Pierrel explained.  “What most people miss is that habitual coffee drinkers develop a blunted cortisol response over time, meaning daily coffee may actually train your nervous system to handle pressure with less reactivity,” she noted.  The study also found caffeine specifically reduced inflammation. “When you lower the noise of inflammation in the brain, you naturally raise the signal of focus and vigilance. That is why moderate daily coffee tends to leave habitual drinkers composed rather than just jittery,” Pierrel pointed out.  Ways to optimize your coffee intake  Of course, you can have too much of a good thing, and how you take your coffee matters, too.  “Two to three cups a day is the sweet spot for gut and brain...

More: Coffee May Alter Gut Microbiome to Reduce Stress (Yes, Even Decaf). Oleg Breslavtsev/Getty Images New research suggests both caffeinated and decaffeinated coffee can improve mood and reduce stress by influencing the gut–brain axis.

TL;DR: Coffee, even without caffeine, can reduce stress, improve learning, and boost mood by influencing your gut-brain axis.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Colorectal, Thyroid Cancer Risk May Be Higher for Males With Infertility

Research shows a possible association between male infertility and the risk of certain cancers. Image Credit: Fiordaliso/Getty Images A recent study has found a possible association between severe male infertility and an increased risk of thyroid and colorectal cancers. The study notes that this association may be due to genetic factors. Certain lifestyle factors may also increase the risk of developing these cancers, such as obesity and diabetes. Around 1 in 6 people will experience infertility at some point in their lives, according to the World Health Organization (WHO) . Previous research has linked male infertility to greater risks of adverse health outcomes, such as cardiovascular diseases and diabetes. Research has also found associations with infertility and an increased risk of testicular cancer and prostate cancer. A recent study published in the European Journal of Epidemiology showed that there may be an association between severe male infertility and non-reproductive cancers, namely thyroid cancer and colorectal cancer. “The study found that men with severe cases of infertility run a higher risk of developing colon cancer and thyroid cancer,” said S. Adam Ramin , MD, board certified urologist, urologic oncologist, and medical director of Urology Cancer Specialists in Los Angeles, CA. Ramin wasn’t involved in the study. “The proposed relationship may be genetic mutations that predispose to cancer but also cause infertility,” he told Healthline. While the study notes the association may be due in part to genetic factors, lifestyle factors, such as smoking, alcohol consumption, obesity, and physical inactivity, may also increase a person’s risk of cancer.  Severe infertility and non-reproductive cancer risk The study used registry data to analyze more than 1.1 million Swedish males who had children between 1994 and 2014. Of these, 14,450 became fathers through the use of intracytoplasmic sperm injection (ICSI) . ICSI is an assisted reproduction technique that is typically used in cases of severe male infertility. The researchers cross-referenced all of the males against the national cancer registry . This revealed a significantly increased risk of thyroid and colorectal cancer among males who had become fathers using ICSI. “This research does not show that use of ICSI causes infertility,” Ramin said. “It merely indicates that men who have very severe infertility, meaning those who need ICSI rather than in vitro fertilization (IVF) , are at higher risk of these cancers.” The researchers also emphasized that the assisted reproductive intervention itself does not cause cancer.  The study notes that more than 2,300 genes are involved in reproductive function. This means that it is plausible that genetic mutations that both impair male reproductive function and increase the risk of cancer may at least partly explain the higher risk of colorectal cancer. Certain lifestyle factors can also increase your risk for various cancers, including colorectal cancer. These include smoking, excessive alcohol consumption, and obesity, which can all also be associated with low semen quality. The study considered the age at which males became parents and their educational level. However, the data used did not include lifestyle factors. Despite this, males with severe infertility appear to be at an increased risk for both reproductive and non-reproductive cancers. “It is important to understand that when an association is found between two medical conditions, it does not mean that the treatment for one of these conditions or the medical condition itself is for sure the reason for [the] development of the secondary condition,” said Ramin. The research team notes that this study should inform future disease prevention initiatives for males seeking care for fertility issues. Screening these men for potential colorectal and thyroid cancer, as well as testicular cancer during treatment and in follow-ups, is one of their suggestions. “Most men who undergo fertility testing are between 30 and 35 years old,” study author Angel Elenkov , docent and researcher at Lund University and consultant physician at the Centre for Reproductive Medicine, Region Skåne, said in a press release .   “The aim is to help them become fathers, and there is no subsequent follow-up on their health. These findings are important from a public health perspective, given that cancers of the colon and rectum, as well as thyroid cancer, are on the rise among younger people. These cancers could be prevented through early screening,” Elenkov continued.  Lifestyle factors that help lower cancer risk Ramin recommended adhering to an overall healthy lifestyle to help reduce cancer risk, such as: avoiding processed foods maintaining a moderate weight and managing obesity limiting alcohol intake quitting or avoiding smoking “It is important to note that a genetic predisposition to [the] development of a certain condition, such as cancer, does not m...

More: Colorectal, Thyroid Cancer Risk May Be Higher for Males With Infertility. Research has also found associations with infertility and an increased risk of testicular cancer and prostate cancer. “The study found that men with severe cases of infertility run a higher risk of developing colon cancer and thyroid cancer,” said S.

TL;DR: Research shows a possible association between male infertility and the risk of certain cancers.

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Healthline May 28, 23:31

Nicole Kidman Says She's Training to Become a Death Doula After Mom’s Passing

Nicole Kidman’s recent announcement that she’s training to become a death doula is increasing visibility for the profession and the need to improve how end-of-life care is approached. Gilbert Flores/Variety via Getty Images Nicole Kidman says she’s training to become a death doula following her mother’s death in 2024. Death doulas provide non-medical support to people nearing the end of life, focusing on emotional, practical, and spiritual care. Experts say growing awareness is helping spark conversations about end-of-life care. Nicole Kidman is drawing new attention to end-of-life care after revealing she’s begun training to become a death doula. The Oscar-winning actor first shared the news during an appearance at the University of San Francisco, where she sat down for a conversation with journalist Vicky Nguyen as part of the university’s Silk Speaker Series, according to the San Francisco Chronicle . Kidman said she was inspired to explore becoming a death doula following the passing of her mother in 2024, an experience that shifted how she thinks about support in a person’s final days. “As my mother was passing, she was lonely and there was only so much the family could provide,” Kidman told attendees, per the Chronicle. “And that’s when I went, ‘I wish there was these people in the world that were there to sit impartially and just provide solace and care.’” “So that’s part of my expansion and one of the things I will be learning,” she added. Kidman later expanded on her decision and the public’s reaction to it during a HISTORYTalks event in Philadelphia. “I did this talk recently where I said I’m expanding into learning to be a death doula, which seemed to have people confused or intrigued,” she said, according to The Hollywood Reporter. Kidman explained that she finds the work of death doulas “fascinating” and “beautiful,” noting that “you have to be a certain personality to be able to do it. But I found out that I’m actually that personality.” “It’s very important to me,” she continued. “There is always suffering, but if there are people there who can help with that, help those final stages be less painful — if you feel the connection in your heart, then that’s lovely. So that’s what I’m exploring.” Kidman’s announcement is bringing increased visibility to the need for death doulas and how they can improve end-of-life care. What is a death doula? According to The International End of Life Doula Association , a death doula­ — sometimes referred to as an end-of-life doula — is “a nonmedical companion who provides personalized and compassionate support to individuals, families, and their circles of care as they encounter and navigate death, loss, and mortality.” They also advocate self-determination and impart “psychosocial, emotional, spiritual, and practical care to empower dignity throughout the dying process.” Unlike doctors, nurses, or other healthcare professionals, death doulas do not provide medical treatment. Instead, they often work alongside existing healthcare teams to offer a wide range of additional support. This support can include sitting with someone in their final days, helping facilitate difficult conversations, or assisting with end-of-life planning, such as advance directives. Raising awareness about death doulas, end-of-life care In addition to Kidman’s announcement, portrayals of death doulas in popular media are also bringing new attention to their role in healthcare. A recent episode of the popular medical drama “The Pitt” featured a nurse acting as a death doula for a terminal patient as she navigated end-of-life care in the emergency department. In a recent interview with Healthgrades , physician and death doula Shoshana Ungerleider , MD, said portrayals like those seen in “The Pitt” can have a real-world impact by helping people better understand end-of-life care and prompting them to think about their own wishes. Ungerleider is also the founder of End Well , a nonprofit focused on improving end-of-life care, and has worked to educate the writers of “The Pitt,” helping guide the show’s depiction of end-of-life moments. That growing awareness, she said, also highlights a deeper issue in how end-of-life care is delivered, and why she founded End Well. “I saw a gap between how we die and how most of us say we want to die,” Ungerleider said. “Over and over, I witnessed patients spending their final days in environments that felt impersonal and overly medicalized. Conversations about what truly mattered were happening too late, or not happening at all.” “I came to understand that dying is not primarily a medical issue. It is a human one,” she added. More research on the impacts of death doulas needed Experts like Ungerleider applaud the increased visibility death doulas have been receiving, hoping it will lead more people to become interested in the field. “I think we need more people who feel called to care for the dying and their loved ones. Death doulas play an important ro...

More: “There is always suffering, but if there are people there who can help with that, help those final stages be less painful — if you feel the connection in your heart, then that’s lovely. More research on the impacts of death doulas needed Experts like Ungerleider applaud the increased visibility death doulas have been receiving, hoping it will lead more people to become interes…

TL;DR: “There is always suffering, but if there are people there who can help with that, help those final stages be less painful — if you feel the connection in your heart, then that’s lovely.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

This Type of Exercise Can Help You Build More Muscle With Less Effort

Eccentric exercise may help build muscle strength with less strain on the body, which may benefit older individuals. DragonImages/Getty Images A lesser-known type of exercise can build strength and improve fitness while remaining accessible to less active individuals. Eccentric exercises like lowering weights or walking downhill can generate more force with less energy while supporting muscle, heart, and even brain health. Whether you’re an advanced athlete or just beginning, eccentric exercise can offer unique benefits to your training regimen. When people think about exercise or weight training , they tend to focus on concentric exercises : those powerful movements that shorten muscles, like curling a dumbbell or powering upward in a squat. Concentric exercise is a well-established way to build muscle and improve fitness, but eccentric exercise , the portion of a movement that lengthens the muscle, may offer additional benefits. Eccentric training, an often-overlooked form of exercise, can help build strength with less perceived effort. Eccentric exercise may help build muscle strength with less strain on the body, according to an article recently published in the Journal of Sport and Health Science . It may also offer specific advantages over concentric exercise for muscle rehabilitation and even brain health. These benefits may be particularly meaningful for certain groups. For older adults and those who are less physically active , eccentric exercise may provide an accessible, low impact form of training that can improve fitness.  Study author Kazunori (Ken) Nosaka , PhD, director of Exercise and Sports Science at Edith Cowan University in Western Australia, said he aims to help normalize eccentric exercise. “Every eccentric contraction counts. People may be discouraged by thinking they have to do lots of exercise to get fitter and healthier. But people can do a small amount of these exercises and still benefit,” Nosaka told Healthline. What is eccentric exercise? Muscles have three fundamental types of contraction : Concentric — muscle shortening, such as lifting a dumbbell. Eccentric — muscle lengthening, such as lowering a dumbbell. Isometric — a static muscle contraction without a change in length, such as holding a plank. In physiology and exercise science, eccentric contractions were not well understood until the mid-20th century. “The word eccentric literally means something that’s odd or peculiar. This type of contraction was given that term because for a long time, scientists weren’t able to explain it. How muscle produces force while it is being lengthened was a big question mark,” said Lindsey Lepley , PhD, associate professor of athletic training, director of the Comparative Orthopaedic Rehabilitation Laboratory (CORL), and co-director of the Orthopedic Rehabilitation & Biomechanics Laboratory (ORB) at the University of Michigan School of Kinesiology. Lepley wasn’t involved in the study. In simpler terms, what puzzled scientists was how a muscle could generate force while being stretched. The concept of a concentric contraction feels intuitive because the muscle is visibly doing the work. However, research into muscle biomechanics has shown that muscles can also produce substantial force during eccentric movements.  Even more unintuitive, muscles may be capable of generating significantly more force — more than 20%, according to Nosaka — than during concentric or isometric contractions , while requiring less metabolic energy.  Benefits and risks of eccentric exercise The biomechanics of eccentric exercise mean it offers unique benefits, but also some drawbacks, compared with more common concentric exercise. For athletes and weightlifters, eccentrics allow for greater mechanical loading: you can literally handle heavier weight during an eccentric than during a concentric, which can aid both strength development and muscle growth . At the same time, eccentric movements tend to be less fatiguing, allowing people to achieve greater training volume through additional repetitions. Research suggests that eccentric exercise may also benefit the brain through neural adaptations related to motor control and coordination. Even for people who are not athletes, eccentric exercise can be a low-friction way to improve fitness. Eccentric exercise is more than just weightlifting: walking downhill and going down stairs are both forms of eccentric exercise — and they both have demonstrated health benefits. A 2017 study found significant multisystemic benefits in older women with obesity after a 12-week program emphasizing eccentric contractions during downhill walking and stair descent. At the end of the program, participants showed improvements in heart rate, systolic blood pressure , oral glucose tolerance , and lipids . “You don’t have to be super fit to walk down a flight of steps. This is helpful to get people who are potentially less fit to be able to see that they can be doing eccentric-b...

More: This Type of Exercise Can Help You Build More Muscle With Less Effort. Eccentric exercise may help build muscle strength with less strain on the body, which may benefit older individuals. Lepley wasn’t involved in the study.

TL;DR: Eccentric exercise may help build muscle strength with less strain on the body, which may benefit older individuals.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Cardiovascular-Kidney-Metabolic Syndrome Tied to Major Risk for Cancer

Healthline Health Conditions Health Conditions All Breast Cancer Cancer Care Caregiving for Alzheimer's Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease (COPD) Digestive Health Ey…

More: Cardiovascular-Kidney-Metabolic Syndrome Tied to Major Risk for Cancer. Healthline Health Conditions Health Conditions All Breast Cancer Cancer Care Caregiving for Alzheimer's Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease (COPD) Digestive Health Eye Health Heart Health Menopause Mental Health Migraine Multiple Sclerosis (MS) Parkinson’s Disease Psoriasis…

TL;DR: Featured Health News All Medicare 2026 Changes Can 6-6-6 Walking Workout Help You Lose Weight?

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Do You Dream in Fear or Joy? The Answer Could Affect Your Morning Mood

Research shows that your dreams may affect your morning mood. Image Credit: Studio Firma/Stocksy A recent study has found that your dreams can affect your mood in the morning.  The study showed that those who experienced fear in their dreams were more likely to have a low mood upon waking. The researchers suggest that dreams may help you process emotions. Sleep is an important part of overall health, but the impacts of your dreams are less well understood. A study recently published in Sleep suggests that the type of dreams you have may influence your morning mood. While the study does not suggest that bad dreams can cause your mood in the morning to be lower, it does show that fear or joy in dreams may play a role in your psychological function. The researchers emphasize the need for further research. “Dreams are such a popular topic in therapy. I find that clients often ask about dream interpretation and trying to understand their meaning, or link their significance to daily life,” said Nicole Andreoli , PhD, licensed psychologist and author of “ Mindfulness & the ADHD Parent .” Andreoli wasn’t involved in the study.   “This is especially true for the more emotionally charged dreams because they do tend to influence morning mood. Many of my clients talk about subsequently waking up experiencing anxiety or depressed mood due to the content of their dreams,” she told Healthline. Fear-based dreams linked to low morning mood The study used data from the Boston College Daily Sleep and Well-Being survey . The researchers analyzed 1,518 participants ages 18 or older. Participants were sent a survey that included a brief sleep diary and a morning mood report. Over the year-and-a-half study, participants completed a maximum of 55 surveys. The surveys included factors like: bed time time they tried to sleep sleep latency (how long it took to fall asleep) how much time they spent awake after falling asleep and getting up in the morning time of last awakening how long they had been out of bed in the morning The participants were also asked about their dreams and how well they could recall them.  They were also given a survey to record how they were feeling and their overall mood in the morning. The researchers found that those who experienced fear in their dreams were 7% more likely to have a lower mood in the morning. Those who experienced a combination of joy and fear in their dreams were around 20% more likely to wake up in a placid mood. Meanwhile, individuals who experienced a high level of joy in their dreams were 9% more likely to wake up in a positive mood. “It has been proposed that REM sleep, in which dreaming occurs, is almost a virtual therapy or sandbox environment,” said Alex Dimitriu , MD, double board certified in Psychiatry and Sleep Medicine and founder of Menlo Park Psychiatry & Sleep Medicine. Dimitriu wasn’t involved in the study.   “In the dream state, and absent any norepinephrine (adrenaline), the brain replays emotional experiences to plans for future ones. Dream sleep is like an emotional playground for the mind. Building on this, people who have more active dream lives may enjoy the benefit of better emotional regulation. Their sleeping brains have had more time in the sandbox. Fear, primal as it is, may be the emotion that requires the most processing in our dreams,” Dimitriu told Healthline.  The researchers also found that people who had higher adaptive emotional regulation were over 3% more likely to be negatively affected by fearful dreams the next day.  However, people with higher-than-average dream fear were also more likely to have higher adaptive emotional regulation. “Those who more actively suppress or avoid emotion may experience less emotionally intense or vivid dreams, and therefore, remember them less,” said Andreoli. “[However], those who use healthier strategies to cope with fear, such as acceptance, are less avoidant of negative emotional experiences. They are more open to engaging with negative emotions, such as fear, making it more likely to show up in dreams,” she explained. These findings show a nuanced relationship between dreams and waking psychological function. While fear in dreams is linked to lower mood the next day, the interplay between adaptive emotional regulation and mixed dream emotions suggests that your dream emotions may play a dynamic and functional role in psychological regulation.  How to start your day with a positive mindset It may be harder to start your day if you wake up in a low mood. However, there are some ways you can shift your mindset toward the positive. “A clean break from sleep to wake helps. Get out of bed, get outdoors in the sunshine, and get moving. Music also moves our emotions deeply — for that drive to the office after a rough night,” Dimitriu said. Andreoli suggested avoiding analyzing your dreams. “Instead, orient to the present moment by naming what’s happening, ‘that dream is still with me’; or narrating what yo...

More: A study recently published in Sleep suggests that the type of dreams you have may influence your morning mood. The researchers emphasize the need for further research. The researchers found that those who experienced fear in their dreams were 7% more likely to have a lower mood in the morning.

TL;DR: Research shows that your dreams may affect your morning mood.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Heart Failure Couldn’t Stop This Couple from Saying ‘I do’ in the ICU

Daniel Phan was in heart failure and days from undergoing lifesaving surgery when he and his girlfriend, Julia, decided to get married — in the ICU. Daniel and Julia Phan on their wedding day in the ICU. Daniel Phan Daniel and Julia Phan met when they were kids after Daniel’s parents hired Julia’s mom to work at their nail salon. “We were the same age. I went to her house when I was, like, eight years old, not knowing she was going to be my future wife,” Daniel told Healthline. While the two drifted apart for several years, they reconnected on Facebook after college in 2014, but it wasn’t until 2023, when they were both in their early 30s, that they began dating. “I reached out because I saw [on Facebook] that she was at a concert and I love concerts, so I asked her if she wanted to go to a concert with me,” said Daniel. “And that’s how it started.” About a year into dating, the couple discussed marriage; however, their path to tying the knot took a turn when Daniel became ill. Living with hypertrophic cardiomyopathy When Daniel was 11 years old, he was diagnosed with hypertrophic cardiomyopathy (HCM), a genetic heart disease in which the heart muscle becomes too thick, making it harder to pump blood. Daniel’s older sister also has the condition, and their mom carried the genetic mutation that causes HCM. Shortly after his diagnosis, he got a pacemaker. “I was excluded from many activities like sports,” he said. “It was a very sad, traumatic time.” Playing guitar and drums became his outlet, and he went through high school without any major health incidents. However, in his early 20s, he had a few occurrences where he over-exerted himself exercising, causing him to pass out and end up in the emergency room. Then in 2024, he began having arrhythmias without exerting himself. On January 15, 2025, he was sitting on his couch watching TV and experienced an intense arrhythmia. “It was the worst one. I was super dizzy, threw up everywhere, my heart wouldn’t calm down…so I called 911, and they showed up, and I ended up in the ER for a week in Gainesville Northeast Georgia,” said Daniel. Because Daniel was in heart failure, he was transferred to Piedmont Heart in Atlanta, where he originally hoped to receive a heart transplant. Turning to LVAD when a heart transplant isn’t an option Circumstances didn’t allow Daniel to receive a heart transplant, and he ended up getting a Left Ventricular Assist Device (LVAD). LVADs are recommended when patients have heart failure that has become refractory to medical therapy, said Sagar Damle, MD, cardiothoracic surgeon at Piedmont Heart. “In this situation, the heart is too weak to adequately pump blood to the entire body, and patients have worsening heart failure. They usually have significant symptoms, such as shortness of breath with activity, fatigue, and tiredness,” he told Healthline. “When medications are no longer effective, LVADs, and sometimes transplant, are the next steps.” The LVAD works like a water pump, taking blood from the left ventricle and sending it to the body through the aorta. “In a nutshell, it effectively functions as the patient’s own left ventricle,” said Damle. “Since most patients who have heart failure have predominantly left ventricular failure, LVADs work very well in that scenario.” A heartfelt moment after heart failure Before undergoing the LVAD surgery, Daniel felt compelled to ask Julia to marry him. “While I was in the hospital, I said, ‘Do you want to marry me?’ She was there every day. It was a huge commitment for her, and we already knew we wanted to be married,” he said. Julia said, “Yes.” “He handed me his mother’s ring, and it fits perfectly,” she told Healthline. The next day, on January 29, 2025, the couple married in the ICU, with their uncle officiating and some of their closest family members and friends in attendance. “We had like 12 or 13 people surrounding Daniel’s bed and around the machines too,” said Julia. “We always joke about how our wedding costs the most, surrounded by expensive machines.” The next day, Julia hustled to the courthouse to get their marriage license and make it official. This meant Daniel could get coverage for the LVAD surgery under Julia’s insurance. “Time was ticking. Daniel was on life support, and the doctors were telling us, ‘the longer you are on life support, the worse you’re going to get,’ and we had to come to a decision,” she said. A few days later, on February 5, 2025, Daniel underwent surgery to receive the Abbott HeartMate 3 LVAD . Married and thriving with an LVAD Recovery was tough for Daniel at first. Being on life support required an extra surgery to repair a damaged vein. “I was super fatigued, still recovering, I could barely walk to my driveway without being out of breath,” he said. Several months of physical therapy got him back to feeling about 80-85% better. “Going up the stairs before the LVAD, I’d need to stop and take a breath,” said Daniel. “Now I can go upstairs, and I’m a...

More: Heart Failure Couldn’t Stop This Couple from Saying ‘I do’ in the ICU. Because Daniel was in heart failure, he was transferred to Piedmont Heart in Atlanta, where he originally hoped to receive a heart transplant. “In this situation, the heart is too weak to adequately pump blood to the entire body, and patients have worsening heart failure.

TL;DR: “In this situation, the heart is too weak to adequately pump blood to the entire body, and patients have worsening heart failure.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

‘Next-Gen’ GLP-1 Leads to 16% More Weight Loss. Is It Better Than Zepbound?

A new GLP-1 drug shows promise for improving metabolic health and treating obesity-related diseases like liver disease. camacho9999/Getty Images A new weight loss drug called survodutide has shown promising results in a phase 3 clinical trial. The drug, which stimulates GLP-1 and glucagon receptors, led to a 16.6% drop in body weight. Survodutide also reduced waist circumference, an indicator of metabolic health. Experts hope the drug will be useful for both obesity and liver disease; however, it is not yet approved for use . Boehringer Ingelheim, a biopharmaceutical company headquartered in Ingelheim, Germany, has announced promising results from its Phase 3 SYNCHRONIZE-1 clinical trial testing survodutide. Survodutide is a novel dual-action drug designed to treat obesity and related metabolic conditions. The trial, conducted across multiple international sites and involving 725 adults living with obesity or overweight but without type 2 diabetes, concluded in April 2026 after 76 weeks of treatment. Survodutide, which activates both glucagon-like peptide-1 (GLP-1) and glucagon receptors, demonstrated significant and sustained weight loss. Participants lost an average of 16.6% of their body weight, a significant improvement compared to just 3.2% in the placebo group.  Treatment with survodutide also showed meaningful metabolic improvements, including reductions in waist circumference, a key predictor of cardiometabolic risk . These findings demonstrate the drug’s potential to improve overall metabolic health and address obesity-related diseases such as liver dysfunction and metabolic dysfunction-associated steatohepatitis (MASH) . Is survodutide safe and effective for weight loss? Survodutide (BI 456906) is similar to the active ingredient tirzepatide ( Mounjaro , Zepbound ) in that it combines two mechanisms of action. However, it acts on a different combination of hormone receptors. While GLP-1 receptor agonists can aid weight loss by reducing appetite and increasing fullness and satiety, survodutide goes a step further by activating glucagon receptors, which are believed to help regulate metabolic functions in the liver.  This is significant because it may allow an additional reduction in liver fat, potentially helping to reduce liver inflammation and fibrosis, two causes of obesity-related complications. The SYNCHRONIZE-1 trial evaluated survodutide’s safety and efficacy in adults with overweight or obesity , excluding those with type 2 diabetes.  Participants received weekly injections of survodutide at doses of 3.6 milligrams or 6.0 milligrams, or a placebo, over nearly a year and a half.  The primary goals of the study were to assess the percentage change in body weight and the proportion of participants achieving at least a 5% reduction in body weight from baseline after 76 weeks of treatment. According to the researchers, up to 85.1% of those treated with survodutide achieved at least a 5% reduction in their weight, contrasting with only 38.8% in the placebo group who reached this goal. On average, people lost 16.6% of their weight, which was equivalent to about 39.2 pounds. The researchers further noted that this was mainly composed of fat rather than lean muscle tissue. Another positive indicator was a significant decrease in waist circumference among the participants. Waist circumference is associated with visceral abdominal fat , which is linked to metabolic dysfunction and cardiovascular risk . The researchers further reported that common GLP-1 gastrointestinal side effects , such as nausea and vomiting , were mostly mild to moderate and temporary. These events occurred mainly during the early phase of treatment when the dose was being titrated up. No new safety concerns emerged during the trial. Full data from the study will be presented at the American Diabetes Association (ADA) 2026 Scientific Sessions in June 2026. How does survodutide compare to other GLP-1s? Hector Perez , MD, lead bariatric surgeon at Renew Bariatrics and an advisor at Bariatric Reports, told Healthline that when it comes to weight loss, it’s too early to call survodutide a “game-changer.” “[W]hile the reported weight loss number is impressive, we already have very strong performers in this category,” he said. Perez, who was not involved in the SYNCHRONIZE-1 trial, cautioned that the full data should be made available before any claims are made about its side effects. “In real life, the best drug is often the one patients can actually stay on,” he said. However, survodutide acts on multiple metabolic pathways, so it could be useful beyond its appetite-suppressing effects, Perez noted. “I’m personally most interested [in] liver disease because a lot of my patients don’t just have obesity, they have fatty liver , elevated liver enzymes, insulin resistance , and visceral fat,” he said. Survodutide may treat liver disease by addressing the underlying metabolic problems that cause fatty liver, such as excess body fat , ...

More: ‘Next-Gen’ GLP-1 Leads to 16% More Weight Loss. A new GLP-1 drug shows promise for improving metabolic health and treating obesity-related diseases like liver disease. Is survodutide safe and effective for weight loss?

TL;DR: A new GLP-1 drug shows promise for improving metabolic health and treating obesity-related diseases like liver disease.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Deadly Hantavirus May Have Spread Among Cruise Ship Passengers, WHO Says

Three passengers have died and several others have fallen ill aboard a cruise ship in a deadly hantavirus outbreak. AFP via Getty Images A cluster of three deaths among passengers aboard a cruise ship in the Atlantic Ocean has been linked to a deadly hantavirus outbreak. Human-to-human transmission of hantavirus is rare, but it appears to have spread among passengers, according to the World Health Organization (WHO). A suspected total of 7 cases has been identified, and investigators are working to manage the outbreak. As the ship prepares to dock in the Canary Islands in Spain, the WHO maintains that the risk to the general public is low. Three people have died and several others have fallen ill aboard a Dutch cruise ship in a deadly hantavirus outbreak. Hantavirus , which typically spreads after exposure to rodent urine, feces, or saliva, may have spread between passengers on a cruise ship, the World Health Organization (WHO) said in a briefing on May 6. The specific hantavirus associated with human-to-human transmission, known as Andes Virus , is present in Argentina, where the MV Hondius, a cruise liner operated by Oceanwide Expeditions, began its voyage. The MV Hondius, currently anchored off the coast of Cape Verde, is expected to dock in the Canary Islands, Spain, in the coming days, sowing fear around the risk of further transmission among locals. Roughly 150 people, including passengers and crew, from more than 20 nations, still remain aboard the ship. The WHO reports that seven cases of hantavirus have been identified — two confirmed “laboratory cases” and five suspected cases. At this time, two of the three deaths have been linked to hantavirus. A married Dutch couple and a German national who were passengers on the ship have died. A British national aboard the ship was evacuated and is being treated in South Africa. That passenger was the first to be diagnosed with hantavirus infection. According to Oceanwide Expeditions, evacuations of sick passengers requiring medical assistance began on May 5. “[We are] working closely with local and international authorities,” said Oceanwide Expeditions in a statement on May 4 . “Strict precautionary measures are in process on board, including isolation measures, hygiene protocols and medical monitoring. All passengers have been informed and are being supported. Oceanwide Expeditions is in close contact with those directly involved and their families, and is providing support where possible.” Human-to-human transmission of hantavirus is exceptionally rare. The WHO, which is managing the outbreak, maintains that the risk to the general public is low. “It’s possible someone got the infection in Argentina, got on the boat, and it spread from person to person. It’s also possible that passengers on the boat got it from the rodents that were already present on the ship,” said Steven Bradfute , PhD, an associate professor at the University of New Mexico Health Sciences Center who specializes in hantavirus research. Bradfute described the situation aboard the cruise ship as unusual. “Usually you have isolated cases, so to hear about a cruise ship with multiple people being infected was definitely not something on our radar,” he told Healthline. Timeline of the hantavirus outbreak at sea The incubation period for hantavirus ranges from 1 to 8 weeks after exposure. This may have complicated investigations aboard the ship and public health risk assessments. The Dutch-flagged MV Hondius, operated by Oceanwide Expeditions, left Ushuaia, southern Argentina, in March, roughly three weeks ago, on a long expedition cruise. Its route included several stops in the Atlantic Ocean, including Antarctica, the Falkland Islands, and Cape Verde. A 70-year-old Dutch man died on April 11 after reportedly developing fever, headache, and abdominal pain . On April 24, his body was removed in Saint Helena, a British territory in the South Atlantic. His wife, a 69-year-old Dutch woman, also disembarked, accompanying his body for repatriation. After disembarking, the woman began showing signs of illness during her journey home. She later died in South Africa at O. R. Tambo International Airport while attempting to return to the Netherlands. On April 27, the same day that the Dutch woman died, a British national aboard the MV Hondius became seriously ill after the ship left St. Helena. The passenger was subsequently transferred to South Africa and treated in Johannesburg. The patient is in critical but stable condition. This case was the first laboratory-confirmed hantavirus infection linked to the incident. Onboard the ship, the situation continued to escalate. A German national died on May 2; details are sparse and the cause of death has not yet been established by Oceanwide Expeditions or the World Health Organization (WHO). Two crew members, one British and one Dutch, have also reported symptoms consistent with possible hantavirus illness. One was described as mild, and the other as...

More: Deadly Hantavirus May Have Spread Among Cruise Ship Passengers, WHO Says. Human-to-human transmission of hantavirus is rare, but it appears to have spread among passengers, according to the World Health Organization (WHO). This may have complicated investigations aboard the ship and public health risk assessments.

TL;DR: This may have complicated investigations aboard the ship and public health risk assessments.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

New Ozempic Pill Could Revolutionize Type 2 Diabetes Treatment. Here's How

Ozempic is now available as a reformulated oral tablet for people with type 2 diabetes. Image courtesy of Novo Nordisk The GLP-1 medication Ozempic is now available in pill form for people with type 2 diabetes. The oral tablet is a reformulated version of the current Rybelsus pill but comes in smaller doses. Experts say the pill may be a better alternative for people who don’t want to administer weekly injections of Ozempic. A pill form of the widely prescribed GLP-1 medication Ozempic is now available in the United States. Officials at Novo Nordisk have announced that an oral tablet version of the GLP-1 drug became available on May 4 for adults diagnosed with type 2 diabetes . The Ozempic pill is replacing Novo Nordisk’s Rybelsus daily oral medication, which was approved in 2019 for type 2 diabetes by the Food and Drug Administration (FDA) in 3 milligram (mg), 7 mg, and 14 mg doses. The Ozempic daily pill is a reformulation of Rybelsus and comes in 1.5 mg, 4 mg, and 9 mg doses. Novo Nordisk officials say the new formulation delivers the same efficacy and safety profile as the originally approved formulation, but at a lower dose. Ozempic will also remain available as a weekly injection for diabetes treatment. It is also commonly prescribed off-label for weight loss. This is the third GLP-1 medication to be approved in pill form this year. In January, FDA regulators gave the OK for another Novo Nordisk product, Wegovy, to be sold as an oral tablet. Wegovy is approved for use for weight management. In April, the FDA also approved the Eli Lilly medication Foundayo in pill form, but the agency ordered the company to study the heart, liver, and other potential risks associated with this new pill. Foundayo has been approved for use in weight management . Novo Nordisk officials say they expect a decision from federal regulators on a 25-mg Ozempic tablet dose by the end of 2026. They add that the new pill provides more options for patients. “With an updated formulation and new branding, oral semaglutide, now under the Ozempic name, helps patients and healthcare professionals more easily recognize the available FDA-approved treatment options for type 2 diabetes that contain the semaglutide molecule,” said Michael Radin , MD, the executive medical director for Novo Nordisk. “By offering Ozempic in both a pill and injection form, patients can work with their healthcare professional to pick the option that best fits their lives and daily routines,” Radin told Healthline. Pouya Shafipour , MD, a family and obesity medicine physician at Providence Saint John’s Health Center in Santa Monica, CA, said a pill form of Ozempic will likely be more appealing to many people than an injection. “A lot of people are needle-averse,” Shafipour told Healthine. “Over the long term, a lot of people get tired of poking themselves.” Mir Ali , MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, said the significance of the new Ozempic-branded pill is that it “carries greater name recognition.” Who’s eligible for the new Ozempic pill? A diagnosis of type 2 diabetes and a prescription are needed for a person to obtain the new Ozempic pill. Novo Nordisk officials say the oral tablet will be available in more than 70,000 pharmacies in the United States. They add that the Ozempic pill will be covered by insurance for most patients with type 2 diabetes, at as little as $25 for a 3-month prescription. People who don’t want to use insurance can purchase the tablets through the NovoCare Pharmacy or certain telehealth providers for $149 for the starting dose of 1.5 mg, $199 per month for the 4 mg pills, and $299 per month for the 9 mg pills. Company officials say the Ozempic pill is effective in improving blood sugar levels when taken in conjunction with a healthy diet and daily exercise. They add that the pill has also proven effective in reducing the risk of major cardiovascular events such as heart attack, stroke, or death in those who are also at high risk for these events. Radin said it’s important for people to know that the Ozempic pill is not the same as the injection. “Oral and injectable Ozempic are not interchangeable. Before a patient considers any transition between formulations, they should consult a healthcare professional,” he said. Ozempic, whether in a pill or an injection, can produce side effects in some people. Some of the common side effects are: abdominal pain constipation diarrhea nausea Shafipour said more GLP-1 medications may be offered in pill form in the near future, as scientists appear to be solving the “absorption issue.” Shafipour explained that injections go directly into the bloodstream, so they are absorbed quickly by the body. He said that pills take longer to be absorbed, so a higher dose has been necessary to achieve the same effectiveness. He said higher doses can lead to more side effects and le...

More: New Ozempic Pill Could Revolutionize Type 2 Diabetes Treatment. It is also commonly prescribed off-label for weight loss. Wegovy is approved for use for weight management.

TL;DR: Ozempic is now available as a reformulated oral tablet for people with type 2 diabetes.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Can ‘Office Air’ Really Affect How Your Skin and Hair Looks?

A new viral theory circulating on social media platforms claims ‘office air’ can negatively affect the health and appearance of your skin and hair. Mihajlo Ckovric/Stocksy “ Office Air Theory” is trending on social media, with claims that office environments can negatively impact skin and hair throughout the day. Experts say there is some truth to the trend, as low humidity and dry indoor air can dehydrate skin. Stress, screen time, hormones, and hygiene habits can also play a role. Staying hydrated, moisturizing, and avoiding touching your face throughout the day can also help. A new theory about skin and hair health has been gaining traction on social media platforms like TikTok. Known as the “office air theory,” proponents claim that indoor environments, such as offices, can negatively affect the appearance and health of skin and hair. In one now-viral TikTok video, creator Noa Donlan attempted to document the effects of “office air,” showing how , at 9 am, her hair appears “clean, skin clear,” and “face not puffy.” However, by 1 pm the same day, her hair is “oily, eye bags dark,” and her face looks “puffy.” In other videos she has shared, Donlan suggests that air quality and other factors in an office environment can contribute to a variety of dermatological issues, including dry or greasy skin and frizzy hair. The comment sections of these videos are full of people sharing similar experiences, which may seem to lend credibility to the claims. But can “office air” really affect the health of your skin and hair, or is it just another overhyped social media trend? How office environments can affect skin and hair Brendan Camp , MD, a double board certified dermatologist at MDCS Dermatology, said the “office air theory” straddles the line between fact and fiction. He explained that when people say “office air” is affecting their skin or hair, they’re usually referring to factors like air conditioning, heating, and ventilation, all of which can contribute to low humidity in a workspace. “A lot of offices do have low humidity levels,” he told Healthline. “The low humidity in offices can pull water from the skin, leading to dehydration.” A little dehydration may not seem like a big issue, but Camp noted that even a small change can make skin look dull and feel dry, which explains why your face may not appear as perky as it did in the early morning. “When the skin is dehydrated , it can sometimes overcompensate by producing more oil,” he said, pointing out that dehydration can also alter your skin barrier. “When you have an altered skin barrier, your skin can be more prone to inflammation, which may present as eczema or even acne.” Other factors can contribute to changing appearance throughout the day Camp said the biggest misconception about the viral “theory” is that “office air” is the primary cause of changes in skin and hair appearance throughout the day. In reality, he said it may be due to other factors. “Beyond air quality, stress is a big one and impacts a lot more than people think,” he said. “Stress causes inflammation, which can impact the skin. On top of that, it can also cause hormonal imbalances , which can further affect your skin.” He noted that screen time can also be a factor. “After a long day of staring at the screen, the eyes may feel strained and can appear more tired looking,” Camp said. Camp also pointed out that shared office environments can harbor a surprising amount of bacteria. Frequently touched surfaces like keyboards, desks, phones, and door handles can transfer germs to your hands and, ultimately, your face. Touching your face throughout the day can introduce germs to your skin, potentially causing irritation, breakouts , or, in some cases, infections. How to protect your skin while at work “Some easy ways to help protect the skin daily are to use a moisturizer to support the skin barrier and keep the skin hydrated,” Camp said. Other helpful habits include using a gentle cleanser morning and night to remove buildup, avoiding touching your face, and keeping items like your phone and keyboard clean. You may also benefit from using a hydrating facial mist during the day, and choosing lightweight, noncomedogenic skin care and makeup products that won’t clog pores. “Don’t forget your daily SPF either,” Camp added. Camp also suggests incorporating a humidifier into your workspace, if possible. “Other things that may help include blue light glasses to reduce eyestrain ,” he said. “It’s also important to manage stress levels , prioritize good sleep, and stay hydrated by drinking water , since dehydration can contribute to dry skin , too.” “Office air theory” is overhyped online Ultimately, while the “office air theory” may be overblown on social media, the underlying factors behind it are real. However, small, consistent habits can make a noticeable difference in maintaining how your skin and hair look and feel throughout the workday.

More: Can ‘Office Air’ Really Affect How Your Skin and Hair Looks?. A new theory about skin and hair health has been gaining traction on social media platforms like TikTok. But can “office air” really affect the health of your skin and hair, or is it just another overhyped social media trend?

TL;DR: A new viral theory circulating on social media platforms claims ‘office air’ can negatively affect the health and appearance of your skin and hair.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Dolly Parton Shares Good and ‘a Little Bad News’ About Her Health

NASHVILLE, TENNESSEE – JUNE 06: Dolly Parton speaks onstage during Kicking Off CMA Fest: A Special Conversation With Dolly Parton Hosted By Rachel Smith at Music City Center on June 06, 2024 in Nashville, Tennessee. (Photo by Terry Wyatt/WireImage) Dolly Parton shared a new health update with fans in an Instagram video. Though she didn’t specify exactly what health issues she’s facing, Parton noted previous challenges with her kidney health as well as weakened immune and digestive systems. The country music legend also revealed that medication side effects forced her to cancel her upcoming Las Vegas shows. Dolly Parton shared “some good news, and a little bad news,” about her health in an Instagram reel posted across her various social media accounts on May 4. “The good news is, I’m responding really well to meds and treatments, and I’m improving every day,” the country music icon said. Parton, 80, didn’t specify exactly what she’s being treated for, but she noted that she’s “always had problems with my kidney stones ,” joking that “they dig more stones out of me a year than the rock quarry in Rockwood, Tennessee.” She further elaborated that her immune and digestive systems “got all out of whack over the past three years,” and that her care team is “working real hard on rebuilding and strengthening those.” She also apologized to fans for needing to cancel her previously postponed Las Vegas shows “because some of the meds and treatments make me a little bit swimmy-headed … and of course, I can’t be dizzy carrying around banjos, guitars and such on five-inch heels.” The new update comes only eight months after Parton originally announced on Instagram that she needed to postpone her Las Vegas concerts due to “health challenges” she was facing that would require “a few procedures.” However, despite the “serious business” of her current health, Parton assured fans that she is “doing really well” and has “great doctors” who told her “everything I have is treatable.” Though Parton said “it’s going to take me a little while before I’m up to stage-performance level,” she hopes to be “up to snuff again soon” and intends to continue working during her recovery. “The truth is, I am still working. I still do videos. I still record. I run up and down to Dollywood now and then,” Parton said. She also noted that she’s “working hard on getting my museum and my hotel open in Nashville later this year,” as well as “spending a lot of time writing and reworking” her upcoming Broadway musical, Dolly: A True Original Musical , which is set to open in “fall or early winter” of 2026. Thank you for standing by me and showing me so much love and support over the past year. I’ve still got some healing to do, but I am on my way! See you soon. 💖 🦋 pic.twitter.com/HXpJqTUJXZ — Dolly Parton (@DollyParton) May 4, 2026 Parton thanks fans for support after husband’s death Parton also thanked fans for the outpouring of love and support she received following the death of her husband, Carl Dean. Dean, who married Parton in 1966 and largely stayed out of the public spotlight throughout their decades-long marriage, passed away on March 3, 2025, at the age of 82. “A lot of you’ve been concerned about me and Carl, and you were so great about that,” she said in the video. “I will always love him, and I will always miss him, but you would be surprised at how much your love and concern meant to me during that time.” “From the bottom of my heart, I thank you,” she continued. “You have been a big part of my healing.” Despite the challenges she’s faced, Parton told fans she remains optimistic about the future and grateful for the support she continues to receive, noting in the video’s caption, “I’ve still got some healing to do, but I am on my way!” This is a developing story. Check back soon for more updates.

More: Dolly Parton Shares Good and ‘a Little Bad News’ About Her Health. (Photo by Terry Wyatt/WireImage) Dolly Parton shared a new health update with fans in an Instagram video. Though she didn’t specify exactly what health issues she’s facing, Parton noted previous challenges with her kidney health as well as weakened immune and digestive systems.

TL;DR: Though she didn’t specify exactly what health issues she’s facing, Parton noted previous challenges with her kidney health as well as weakened immune and digestive systems.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Ultra-Processed Foods Linked to Heart Disease, but Healthy Swaps May Lower Risk

European scientists are advocating for more education on the health harms of ultra-processed foods. Trinette Reed/Stocksy European scientists say ultra-processed foods increase the risks of a variety of health ailments, particularly heart disease. They recommend that medical professionals discuss the health dangers of ultra-processed foods with their patients. Experts agree that doctors should advise their patients on how to identify ultra-processed foods and reduce them in their daily diets. European scientists say that medical professionals aren’t doing enough to warn the public about the health dangers of ultra-processed foods . The scientists are urging doctors to talk with their patients about the amount of ultra-processed foods they eat and how to reduce them in their daily diets. They said those discussions should include an explanation that many foods marketed as “healthier” are often ultra-processed. The scientists said this guidance is particularly important for people at risk for heart disease. They further noted that most dietary guidelines prioritize nutrient-centered recommendations but don’t address food processing. The scientists recommended that medical professionals promote better public understanding of food labeling , food regulation, and updated guidelines. They reached their conclusions by reviewing all published research on ultra-processed foods and cardiovascular health. The findings were published in a clinical consensus statement in the European Heart Journal on May 6. The scientists are from the European Society of Cardiology’s Council for Cardiology Practice and the European Association of Preventive Cardiology , along with a group of topic experts. “[Ultra-processed foods], made from industrial ingredients and additives, have largely replaced traditional diets,” Luigina Guasti , MD, an associate professor at the University of Insubria in Italy and a co-author of the statement, said in a press release . “Research suggests these foods are linked to several risk factors for cardiovascular disease, such as obesity , diabetes, and high blood pressure, and to the risk of developing and dying from heart disease . However, this evidence has not yet made its way into the advice we give to patients on healthy eating,” Guasti continued. Health dangers of ultra-processed foods Ultra-processed foods are foods that have been altered from their original form and contain additives such as sugar and salt, as well as substances that aren’t typically used in culinary preparations. Those additional substances add flavor and texture to foods but can also increase the risk of several diseases. A 2023 research review and analysis reported that there are associations between ultra-processed foods and an increased risk of several diseases. These include: hypertension diabetes obesity dyslipidemia A 2025 study concluded that ultra-processed foods are tied to more than 120,000 preventable deaths in the United States every year. Recent research has also linked ultra-processed foods to worse muscle health, weakened bones, and fertility issues in females. Further, research has linked ultra-processed foods to an increased risk of cancer mortality as well as a higher risk of cognitive decline . The European scientists reported that adults with a high consumption of ultra-processed foods have a 19% higher risk of coronary artery disease , a 13% higher risk of atrial fibrillation (AFib) , and as much as a 65% higher risk of cardiovascular-related death compared with adults with a lower consumption of ultra-processed foods. They added that ultra-processed foods also worsen key risk factors for conditions such as obesity, type 2 diabetes , high blood pressure, and the buildup of unhealthy fats in the bloodstream. They reported that the risk from ultra-processed foods seems to be consistent across large, diverse populations. Cheng-Han Chen , MD, an interventional cardiologist and medical director of the Structural Heart Program at MemorialCare Saddleback Medical Center in Laguna Hills, CA, wasn’t involved in the study, but agreed with the scientists’ recommendations. “This review of the current evidence regarding the health effects of ultra-processed foods makes it clear that consumption of ultra-processed foods is associated with increased risk of cardiovascular disease,” Chen told Healthline. “We need to better educate the public on the risks of these foods and on the need to prioritize eating whole foods.” Jennifer Wong , MD, a cardiologist and medical director of Non-Invasive Cardiology at MemorialCare Heart and Vascular Institute at Orange Coast Medical Center in Fountain Valley, CA, echoed this sentiment. Wong wasn’t involved in the study. “This [paper] highlights an important and increasingly relevant issue — the impact of ultra-processed foods on cardiovascular health,” she told Healthline. “Bringing attention to this topic is critical given how prevalent these foods are in modern diets.” ...

More: Ultra-Processed Foods Linked to Heart Disease, but Healthy Swaps May Lower Risk. They reached their conclusions by reviewing all published research on ultra-processed foods and cardiovascular health.

TL;DR: European scientists are advocating for more education on the health harms of ultra-processed foods.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

FDA Blocks Publication of Vaccine Safety Studies. Why Experts Are Concerned

The FDA has blocked the publication of COVID-19 and shingles vaccine safety studies. What does this mean for public health? Image credit: Gerardo Vieyra/NurPhoto via Getty Images The Food and Drug Administration (FDA) has blocked the publication of COVID-19 and shingles vaccine safety studies, citing concerns over their conclusions. Experts question the decision to withdraw the studies, since both vaccines have substantial evidence supporting their safety and effectiveness. Some experts say the decision may be influenced by HHS Health Secretary Robert F. Kennedy Jr.’s anti-vaccine agenda. The Food and Drug Administration (FDA) has pulled back the publication of several studies on the safety and efficacy of broadly used COVID-19 and shingles vaccines. The Department of Health and Human Services (HHS), which oversees the FDA, confirmed the decision, which was first reported by The New York Times . The studies, which involved millions of patient records and taxpayer dollars, were conducted by FDA scientists and data contractors before they were blocked from publication. Two studies on COVID-19 vaccines that were accepted by medical journals were withdrawn in October 2025 before they were published. The FDA also failed to sign off on two safety studies on the shingles vaccine, Shingrex, which required the federal agency’s approval prior to their submission to a drug safety conference. The Department of Health and Human Services couldn’t be reached for comment, but an HHS spokesperson told The New York Times that the studies were blocked due to concerns about their conclusions. “Scientists and physicians aren’t buying that explanation,” said Robert Glatter , MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hospital in New York City, and assistant professor of Emergency Medicine at Zucker School of Medicine at Hofstra/ Northwell. “The public health implications of blocking such studies are serious … secrecy can backfire. People who are already distrustful may see suppression where officials see caution,” Glatter told Healthline. A robust body of evidence supports the safety and effectiveness of both COVID-19 and shingles vaccines, which has experts concerned about the FDA’s decision to pull the recent studies. Monica Gandhi , MD, MPH, a professor of medicine at the University of California, San Francisco, echoed Glatter’s remarks. “The COVID-19 vaccine safety studies had been peer reviewed and would have been extremely important to be published for reassurance of the public of the safety of these vaccines,” she said. William Schaffner , MD, professor of preventive medicine and infectious diseases in the Department of Health Policy at Vanderbilt University Medical Center in Nashville, agreed. “Both vaccines are in widespread use, not only here in the United States, but around the world. Having these data available so that professional people can look at them and make their own assessments when they see the data is very important.” We spoke with infectious disease experts unaffiliated with the studies to find out why scientific research might be barred from publication, and why it’s potentially problematic to block it from public view. These interviews have been lightly edited and condensed for clarity and length. The opinions expressed in this article do not necessarily reflect the views of Healthline Media. Why is the FDA’s decision to pull the publication of two studies a concern? Gandhi: I am extremely concerned about the FDA’s decision to pull publications of well-conducted studies documenting the safety of COVID-19 vaccines, as well as a study showing the effectiveness of the Shingrix vaccine in preventing shingles.  The COVID-19 safety studies reviewed side effects of these vaccines among millions of people with data collected by FDA scientists from Medicare and other insurance databases, and found the vaccine to be safe among those who are 65 and older and those between the ages of 6 and 64 years. The FDA’s decision suggests a political rather than a scientific motivation and aligns with the anti-vaccine views of the Secretary of the Department of Health and Human Services, Robert F. Kennedy Jr. Glatter: The broad reaction from my colleagues and myself is skepticism and outrage toward the decision itself, not because every study is beyond criticism, but more to the point that withholding research is viewed as unethical and irresponsible. In science, disagreement is normally handled through peer review, editorial commentary, replication, and publication of rebuttals, not by stopping publication of a research paper altogether. That is especially true for vaccines, where confidence depends on showing the public both the evidence and the process. Federal health agencies themselves routinely argue that transparency is essential to trust, and the FDA has recently emphasized the importance of making trial results public to avoid distorted perceptions of safety and efficacy. W...

More: FDA Blocks Publication of Vaccine Safety Studies. What does this mean for public health? “The public health implications of blocking such studies are serious … secrecy can backfire.

TL;DR: What does this mean for public health?

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

New Breast Density Treatment May Have Fewer Side Effects, Lower Cancer Risk

New research found that the drug endoxifen reduced mammographic breast density with fewer side effects. praetorianphoto/Getty Images A study has found promising results with the breast cancer prevention drug (Z)-endoxifen. The drug reduced breast density safely and with fewer side effects than tamoxifen . It also had fewer troublesome side effects than this standard preventive treatmen t. Experts say that if further research confirms these findings, the endoxifen could help increase compliance and improve outcomes. Nearly half of all females ages 40 and older have dense breasts , which can impact breast cancer risk . A clinical trial published in the Journal of the National Cancer Institute on April 27 revealed promising results for a new breast cancer prevention approach targeting breast density. The protocol involves low doses of (Z)-endoxifen, a metabolite of the well-known drug tamoxifen .  The study, known as the KARISMA Endoxifen trial, tested the effects of two daily doses of (Z)-endoxifen on mammographic breast density , a known marker of breast cancer risk and treatment response.  Researchers examined whether (Z)-endoxifen could reduce breast density safely and with fewer side effects than tamoxifen, potentially offering a new option for breast cancer prevention. Here’s what they found. Studying the effects of endoxifen on breast density The KARISMA Endoxifen trial was a double-blind, randomized, placebo-controlled phase II study that enrolled premenopausal women ages 40 to 55. Researchers recruited 240 healthy participants from Sweden’s national breast cancer screening program between December 2021 and November 2023. To be eligible, participants needed to have regular menstrual cycles or confirm premenopausal status via blood tests, and to have a baseline mammogram showing measurable breast density. Women taking medications that could interfere with endoxifen metabolism were excluded. Participants were randomly assigned to one of three groups receiving daily oral capsules for six months: a placebo, 1 milligram (mg) of (Z)-endoxifen, or 2 mg of (Z)-endoxifen. The study was “double-blinded,” meaning neither the participants nor the researchers knew who was receiving which treatment until the trial was completed, ensuring unbiased results. Mammographic breast density was measured from full-field digital mammograms obtained at the start, 3 months, 6 months, or upon early discontinuation. A specialized automated method, STRATUS, assessed breast density area in square centimeters, and images were aligned to reduce measurement errors. Safety and tolerability were evaluated throughout the study by monitoring vital signs and blood chemistry, and by assessing participant-reported side effects via a digital application and questionnaires. Tolerability was assessed using the Breast Cancer Prevention Trial Eight Symptom Scale (BESS Plus), a validated symptom questionnaire, supplemented with questions specific to tamoxifen-related symptoms based on previous research. The trial’s main goal was to determine whether either dose of (Z)-endoxifen was better than placebo at reducing mammographic breast density, a proxy for breast cancer risk reduction. Statistical analysis focused on relative changes in breast density adjusted for baseline values and compared the results between placebo and active treatment groups. Endoxifen reduced breast density with fewer side effects Of the over 126,000 females invited to participate, 240 were enrolled and randomly assigned to the three treatment groups, with 75 females in each group completing baseline and end-of-treatment mammograms for analysis. The groups were balanced in terms of age, body mass index (BMI) , smoking status, and family history of breast cancer. The key finding was that both doses of (Z)-endoxifen significantly reduced mammographic breast density compared to placebo. Females receiving 1 mg of (Z)-endoxifen showed a 19.3% reduction in breast density, while those on 2 mg experienced a 26.5% reduction. In contrast, the placebo group showed virtually no change. These reductions are comparable to those previously seen with the standard 20 mg dose of tamoxifen used for breast cancer prevention and treatment. Blood tests confirmed that (Z)-endoxifen levels in the blood corresponded with the doses given, with average plasma concentrations of 4.75 ng/mL in the 1 mg group and 9.69 ng/mL in the 2 mg group. However, breast density reduction plateaued at concentrations of 3-4 ng/mL, suggesting that higher doses may not provide additional benefit. Regarding safety, the overall number of adverse events (AEs) reported was similar across all groups; however, more women in the (Z)-endoxifen groups reported side effects related to the study drug. The most frequently reported side effects in the treatment groups included: irregular menstrual cycles night sweats hot flashes Additionally, the 1 mg dose had fewer participants discontinue treatment due to side effects than ...

More: Experts say that if further research confirms these findings, the endoxifen could help increase compliance and improve outcomes. Nearly half of all females ages 40 and older have dense breasts , which can impact breast cancer risk .

TL;DR: New research found that the drug endoxifen reduced mammographic breast density with fewer side effects. praetorianphoto/Getty Images A study has found promising results with the breast cancer prevention drug (Z)-endoxifen.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

She Was Diagnosed with HIV in 1996 and Still Thriving Today at 74

Barbara Roberts has lived with HIV for 30 years. Now, a new FDA-approved medication is changing how she manages it at the age of 74. Barbara Roberts (pictured above) was diagnosed with HIV at the age of 44. Today, at 74, she continues thriving with the help of a new FDA-approved medication. In 1996, Barbara Roberts thought she had a bad case of the flu that wouldn’t go away. After several days of experiencing a high fever and sweating, she decided to go to the emergency room, where she was sent home with antibiotics. “I just still didn’t feel well,” Roberts told Healthline. “And I remember going back to the emergency room.” She stayed in the hospital for three days while doctors ran tests. On December 21, 1996, Roberts was diagnosed with HIV . She was 44 years old. “It surprised me because it never occurred to me that that’s what was going wrong with me,” she said. “I was in total shock, disarray, scared to death because back then, it was like a death sentence.” In fact, in 1996, the total life expectancy for a 20-year-old person with HIV was 39 years. In 2011, the total life expectancy jumped to about 70 years. Roberts left the hospital with a medication regimen and visited an HIV clinic for guidance. “Everyone was so nice to me there. They were so kind and calmed all my fears; they tried to at least,” said Roberts. Initially, her medications helped ease symptoms, and she felt better. However, a year after her diagnosis, Roberts became extremely tired and experienced shortness of breath and nosebleeds. She also noticed that the skin on her hands and the bottom of her feet darkened. An intense nosebleed led her back to the ER, where doctors discovered she had significantly low blood platelets. For 25 days straight, she received blood and platelet transfusions in the hospital. During this time, doctors determined that one of her medications caused her symptoms, and they adjusted accordingly. “After that, I have never gone back to the hospital or had any problems with my medications, and I’ve had different ones over the years,” said Roberts. Participating in a clinical trial changed how she manages HIV In 2021, Roberts’ primary care physician, Debbie Hagins , MD, medical director of the Coastal CARE Centers in southeast Georgia, asked if she would like to participate in a clinical trial for try Idvynso , a daily two-drug single-tablet treatment for people with HIV who are virally suppressed.  “She explained the medication to me and asked if I would like to be in a study,” said Roberts. “I felt it was a privilege for her to ask me to be in this study.” She decided to enroll in the clinical trial because she couldn’t pass up the opportunity to take only one medication a day. “The only thing I remember from initially taking the medication was I had really vivid dreams for about two weeks, and it’s been smooth sailing [since],” said Roberts. On April 21, 2026, the FDA approved Idvynso. Roberts continues to participate in the clinical trial as part of an open-label extension, in which additional data are collected to better understand the drug’s long-term safety profile. Idvynso is the only medication she now takes, aside from Vitamin D and folic acid supplements . While she lives with age-related back pain and arthritis , at 74 years old, she said she’s grateful she doesn’t live with any other chronic conditions that require medication. “I hear of people [having to take] many different medications in a day because their HIV had caused them so many other problems like organs breaking down and skin tissue issues, so that was a reason that I decided to get in the study…if this could help me, why shouldn’t I be able to help someone else?” HIV is a manageable chronic disease, but it is associated with additional increased health risks Hagins said that although HIV is a chronic and manageable disease, it is associated with increased risks of bone, cardiovascular, and renal diseases, and accelerated aging. “Prescribing the least amount of medication and at the lowest dose possible to achieve the desired goal is always the objective,” Hagins told Healthline. An HIV provider since 1989, Hagins said she witnessed treatment undergo revolutionary advances. She remembers patients who felt that the treatment was worse than the disease and whose quality of life was reduced. “They gave up their dreams of having a family, of traveling, of pursuing a career, and the like,” she said. “Today, with HIV medications like Idvynso, persons living with HIV no longer embrace those limitations.” However, she said more treatment options are needed, especially because those living with HIV require lifelong treatment, which can cause unwanted side effects that may not appear until several years into treatment. “And though our currently FDA-approved medications have not changed in their efficacy, people change. As we age, our bodies respond and react to illnesses and their treatments differently with each decade of life,” said Hagins. “It i...

More: “After that, I have never gone back to the hospital or had any problems with my medications, and I’ve had different ones over the years,” said Roberts. “I hear of people [having to take] many different medications in a day because their HIV had caused them so many other problems like organs breaking down and skin tissue issues, so that was a reason that I decided to get in the…

TL;DR: Barbara Roberts has lived with HIV for 30 years.

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Healthline May 28, 23:31

Weight Loss Surgeries Decline as GLP-1 Use Skyrockets. Why This Matters

The number of people getting bariatric surgery for weight loss has declined, partly due to the rise of GLP-1 medications. KARRASTOCK/Getty Images A new study has found a decline in the number of people getting bariatric surgery for weight loss. The widespread availability of GLP-1 medications and weight management programs is likely contributing to this trend. Experts say that bariatric surgery has been shown to be an effective long-term strategy for weight loss . Bariatric surgery also has quick recovery times due to procedural advancements, such as laparoscopic techniques. Your doctor can help you decide whether weight loss surgery or weight loss drugs are best for you. Until recently, bariatric surgery was considered a first-line treatment for weight loss. Now, a recent study from Loyola University Chicago researchers has uncovered a significant shift in the bariatric surgery landscape. The study’s authors aimed to understand how the types and numbers of bariatric surgeries have changed in response to the growing popularity of GLP-1 drugs and other weight loss treatments . After examining data from 2020 to 2024, the researchers observed a decline in the number of bariatric surgeries performed across the United States. The findings have not yet been published in a peer-reviewed scientific journal, but were presented during the American Society for Metabolic and Bariatric Surgery (ASMBS) Annual Meeting from May 3–7 in San Antonio, TX. The study highlights how patients and doctors are increasingly opting for surgery alternatives, reflecting evolving attitudes and options to treat obesity. Bariatric surgeries decline in recent years Bariatric surgery, which includes procedures like sleeve gastrectomy and gastric bypass , has long been considered an effective solution for severe obesity. However, as noninvasive therapies advance, it’s important to track how these shifts affect surgical practices and patient choices. To investigate these trends, the researchers analyzed a large national database called the ACS-MBSAQIP, which tracks bariatric surgeries performed in the United States. They focused on surgeries performed from the beginning of 2020 through 2024, including both initial weight loss surgeries and follow-up revision or conversion procedures — procedures performed to modify or adjust earlier operations. The data revealed that the overall number of bariatric surgeries reached its highest level in 2022, then declined in the following years. This drop reflects a growing preference for nonsurgical options among patients and healthcare professionals. Alongside this reduction, the study found that the types of surgeries being performed have also shifted. One key finding is a decrease in the frequency of sleeve gastrectomy , a common procedure in which a portion of the stomach is removed to reduce its size. While still the most popular surgery, its share of total procedures has steadily decreased since 2020.  In contrast, Roux-en-Y gastric bypass surgeries — which create a small stomach pouch and reroute the intestines — have become more common, particularly as conversion surgeries. Many people who initially had a sleeve gastrectomy later undergo a gastric bypass to further aid weight loss or address complications. Additionally, the study noted an overall increase in other bariatric procedures, including sleeve gastrectomy, gastric bypass, and lap-band surgeries . This suggests that surgeons and patients are exploring a wider variety of surgical options tailored to individual needs. By examining these trends, the study sheds light on how the field of weight loss treatment is evolving. It underscores the importance of ongoing research and adaptation in medical practice as new therapies emerge and patient preferences evolve. Bariatric surgery vs. GLP-1s: Which is best for weight loss? John DeBarros , MD, Chief Medical Officer at Pivot Weight Loss Center, said he doesn’t necessarily feel this trend is either positive or negative for those seeking help with weight loss. DeBarros wasn’t involved in research. “The honest answer would be it depends,” he told Healthline. “It depends on the reason why patients are making that choice.” If they have researched their options and discussed their decision with a qualified surgeon before making their decision, and they still feel that a GLP-1 medication is best for them, that’s patient-centered care, according to DeBarros. “What very much concerns me deeply, however, is when patients bypass surgery simply because GLP-1 feels easier or the less intimidating choice,” he said. “I think the decline in bariatric surgery becomes a grave problem when patients with severe obesity, those with a BMI of 35+ with serious comorbidities , without understanding that surgery may be infinitely more effective for them,” said DeBarros. Sergey Terushkin, MD, a bariatric surgeon with ThinEra, added that he thinks the conversation around GLP-1 medications has become too extreme on both sides...

More: Weight Loss Surgeries Decline as GLP-1 Use Skyrockets. Your doctor can help you decide whether weight loss surgery or weight loss drugs are best for you. GLP-1s: Which is best for weight loss?

TL;DR: The number of people getting bariatric surgery for weight loss has declined, partly due to the rise of GLP-1 medications.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Hantavirus Arrives in U.S.: Could Cruise Ship Outbreak Cause Next Pandemic?

As passengers aboard a cruise ship linked to a deadly hantavirus outbreak return to their home countries, experts say the risk of another pandemic remains low. Chris McGrath/Getty Images 18 American passengers have been airlifted home to the U.S. after a deadly hantavirus outbreak aboard an Antarctic expedition cruise ship. Investigators believe the rare Andes virus strain may have spread among passengers in the ship’s close quarters. Experts say the outbreak highlights the severity of hantavirus, but stress that the broader risk of a COVID-like pandemic remains low. Health officials say that 18 Americans have returned safely to the United States after traveling on a cruise ship in the Atlantic linked to a deadly hantavirus outbreak. The U.S. State Department airlifted the passengers from the Spanish island of Tenerife on May 10. Two of those passengers are being treated in biocontainment units “out of an abundance of caution,” according to the Health and Human Services X account . One passenger tested positive for hantavirus, while the other developed mild symptoms, officials said. Of the repatriated Americans, 16 are being treated at an ASPR Regional Emerging Special Pathogen Treatment Center in Omaha, NE. Two others are being treated at a RESPTC in Atlanta, GA. The Americans are among dozens of passengers monitored as international health officials continue investigating the outbreak aboard the ship. The Dutch-flagged MV Hondius departed from southern Argentina on April 1 with roughly 150 passengers and crew aboard for an expedition cruise through the Atlantic Ocean. Just 11 days into the voyage, a 70-year-old man died after developing fever, headaches, and abdominal pain. After several additional passengers became ill, the World Health Organization (WHO) identified the ship as the site of a hantavirus outbreak . As of May 12, the number of confirmed hantavirus cases linked to the ship rose to 11 , according to the WHO. Three deaths have also been confirmed: a Dutch married couple and a German national. All remaining passengers have disembarked and are being repatriated to their home countries, according to the latest statement from Oceanwide Expeditions, the ship’s operator. The WHO stated that while it expects to see more hantavirus cases, the broader public risk remains low. “We expect more cases given the dynamics of spread on a ship and the virus’ incubation period,” the agency wrote on X on May 12. “At the moment, there is no sign that we are seeing the start of a larger outbreak.” Still, repatriation efforts of cruise ship passengers have fueled fears of another pandemic — concerns that experts say are overstated.  “I think we’re actually in very good shape,” said Lina Moses , PhD, an epidemiologist and disease ecologist at Tulane University’s Celia Scott Weatherhead School of Public Health & Tropical Medicine, who specializes in rodent-borne diseases. “It’s not surprising we’re starting to see more suspected cases. That means that the process is working right. They are monitoring people effectively and identifying people as they become ill,” Moses told Healthline. Could hantavirus cause the next pandemic? Pandemic fears have largely been driven by what is believed to be human-to-human transmission of hantavirus aboard the Hondius, a rare but documented phenomenon. Hantavirus is typically transmitted through exposure to the urine or droppings of infected mice and rats. The virus can survive in dust and debris, and when that dust is inhaled, infection can occur. However, one strain of hantavirus endemic to South America, the Andes virus , has been linked to cases of human-to-human transmission. It is the only hantavirus known to spread from person to person. The leading theory on the outbreak aboard the Hondius is that an individual carrying the Andes virus boarded the ship and subsequently passed it on to other passengers. Experts say that the level of transmission aboard the ship is reasonable given the circumstances and does not indicate anything out of the ordinary. “Previously, we’ve seen person-to-person spread with Andes virus in situations such as close household contacts or at a large social gathering. There’s nothing here that is remarkably different from what we’ve seen in the past,” said Steven Bradfute , PhD, an associate professor at the University of New Mexico Health Sciences Center who specializes in hantavirus research. Researchers have documented this transmission in Argentina , including “super spreader” events that resulted in numerous infections at once. Cruise ships can be the perfect environment for disease outbreaks, such as norovirus, which have been documented regularly . “The most plausible explanation is that the passengers of the cruise ship likely became infected before boarding the cruise, then human-to-human transmission occurred among close contacts,” said Robert Glatter , MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hos...

More: Hantavirus Arrives in U.S.: Could Cruise Ship Outbreak Cause Next Pandemic?. As passengers aboard a cruise ship linked to a deadly hantavirus outbreak return to their home countries, experts say the risk of another pandemic remains low. Experts say the outbreak highlights the severity of hantavirus, but stress that the broader risk of a COVID-like pandemic remains low.

TL;DR: As passengers aboard a cruise ship linked to a deadly hantavirus outbreak return to their home countries, experts say the risk of another pandemic remains low.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Healthgrades Names America’s Top Hospitals for Patient Experience in 2026

Healthgrades has announced the recipients of the 2026 Outstanding Patient Experience Awards. Healthgrades recently announced the recipients of the 2026 Outstanding Patient Experience Awards . The awards recognize hospitals that excel at delivering top-quality care while ensuring a positive patient experienc e. The 2026 recipients include 373 hospitals from 46 states and represent the top 15% of hospitals nationwide for patient experience. Healthgrades has announced the recipients of the 2026 Outstanding Patient Experience Awards , which recognize “hospitals that excel at delivering top-quality care while ensuring a positive patient experience.” The recipients for this year represent the top 15% of hospitals nationwide for patient experience and include 373 hospitals from 46 states. Texas is home to the most 2026 award-winners, with 31 hospitals recognized, followed by Wisconsin with 28, Pennsylvania with 25, and California and Ohio with 23 each. Of this year’s winners, only 16 hospitals were triple recipients, earning the Outstanding Patient Experience, Patient Safety Excellence, and America’s Best Hospitals distinctions. However, 80 hospitals were dual recipients, earning both the Outstanding Patient Experience Award and the Patient Safety Excellence Award. “Better patient experiences are correlated with better health outcomes, which is why patients should always consider patient experience during the care search,” Alana Biggers , MPH, medical advisor at Healthgrades, said in a press release . “Healthgrades’ Outstanding Patient Experience Award recognizes hospitals that prioritize high-quality, patient-centered care and ensure that patients feel heard, empowered, and confident throughout the care journey.” How the 2026 Outstanding Patient Experience Award recipients were evaluated To determine the recipients of the 2026 Outstanding Patient Experience Awards, Healthgrades analyzed Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey data collected from patients and submitted to the Centers for Medicare and Medicaid Services (CMS). The surveys ask patients about multiple aspects of their hospital experience, including: communication with doctors and nurses staff responsiveness discharge information room cleanliness hospital quietness Hospitals were required to submit at least 100 surveys to be considered for the awards. Healthgrades evaluated hospitals across 10 patient experience measures to identify facilities with the highest overall patient experience scores nationwide. According to the organization, doctor communication, nurse communication, and clear communication during discharge were the factors most strongly associated with whether patients would recommend a hospital to friends and family. Healthgrades also noted that the findings highlight the important role communication and patient-centered care can play in how patients perceive their hospital experience. How awards like these can help patients make better decisions about their care While awards like these recognize hospitals for high quality performance, experts say they can also help patients make more informed choices about where they receive care. “These insights give individuals and families the information they need to make confident and better-informed healthcare decisions,” Biggers said in a previous press release announcing its 2026 Patient Safety Excellence Awards . However, Healthgrades also notes that these awards are not recommendations or endorsements for particular hospitals, and patient experience scores should not be used alone to determine a hospital’s quality of care. Patients should consider multiple factors when making healthcare decisions, including their own medical needs, physician recommendations, insurance coverage, and access to specialty care. The full 2026 Outstanding Patient Experience Awards recipient list and methodology are available on the Healthgrades website. *Healthgrades and Healthline are part of the RVO Health portfolio of brands.

More: Healthgrades Names America’s Top Hospitals for Patient Experience in 2026. Healthgrades has announced the recipients of the 2026 Outstanding Patient Experience Awards. How awards like these can help patients make better decisions about their care While awards like these recognize hospitals for high quality performance, experts say they can also help patients make more informed…

TL;DR: Healthgrades has announced the recipients of the 2026 Outstanding Patient Experience Awards.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

PCOS Is Now PMOS: Doctors Say Name Change Will Improve Diagnosis, Care

After years of debate, global experts announced that PCOS will now be called PMOS to better reflect the multisystem effects it has on the body. Image Credit: ruizluquepaz/GettyImages Global experts have officially announced a change in name for polycystic ovary syndrome (PCOS). The condition will now be known as polyendocrine metabolic ovarian syndrome (PMOS). This name change was made to reflect the multisystem effects the condition has on the body. In a culmination of more than 10 years of global consultation, polycystic ovary syndrome (PCOS) has officially been renamed as polyendocrine metabolic ovarian syndrome (PMOS). This hormonal disorder affects an estimated 1 in 8 females worldwide. The name change was announced at the European Congress of Endocrinology in Prague and was published in The Lancet on May 12. “Polycystic ovarian syndrome or PCOS has long been a confusing and misleading diagnosis for women that has not properly described this underdiagnosed medical condition,” said Sherry Ross , MD, board certified OB-GYN and Women’s Health Expert at Providence Saint John’s Health Center in Santa Monica, CA. “Using the updated name of polyendocrine metabolic ovarian syndrome, or PMOS, gives a more accurate and inclusive name to this medical condition, which affects women far beyond the ovaries,” she told Healthline. PCOS name change: PMOS reflects multisystem disease Over the past 14 years, 56 academic, clinical, and patient organizations have been campaigning to change the name of PCOS. The aim was to prioritize a new, accurate name rather than retaining the PCOS acronym or a generic name. The preferred terms to focus on were ovarian, metabolic, and polyendocrine in order to reflect the condition’s multisystem effects. This led to a consensus for the new name, PMOS. “By putting ‘endocrine’ and ‘metabolic’ in the name, PMOS tells clinicians this is a whole-body condition, not just a gynecologic diagnosis,” said Steven Vasilev , MD, gynecologic oncologist specializing in endometriosis and founder of the Lotus Endometriosis Institute in Santa Monica, CA. The accuracy of the name was improved by omitting cysts and emphasizing metabolic, endocrine , and ovarian dysfunction. It was important to omit “ cysts ” because not everyone with PCOS will experience ovarian cysts . “PCOS has long been linked to polycystic ovaries seen on ultrasound, which is misleading, since [the] ovaries of affected patients can be completely normal. Having normal ovaries does not mean you do not have PCOS, and here lies the confusion,” Ross said. “Renaming PCOS to PMOS creates a better backdrop to really understanding this multisystem endocrine condition. PMOS better identifies the patient experience of those who are suffering from the complex symptoms associated with this condition,” Ross continued. “PMOS provides more transparency and less confusion for those experiencing symptoms associated with this condition,” she said. Why did PCOS’s name change? The name “polycystic ovary syndrome” has long been recognized as a limiting and inaccurate name. This misrepresentation has led to various consequences, including: diagnosis delays fragmentation in care stigma missed opportunities regarding early intervention for metabolic and cardiovascular risks The new name, PMOS, addresses these issues in a few different ways: reflects the hormonal complexity acknowledges the condition’s strong metabolic and cardiometabolic effects continues to focus on the role of ovaries in the condition without overemphasizing the reproductive aspects The experts who were part of the renaming effort noted that this change may help to reshape how the condition is diagnosed, treated, and researched globally. “The new name should help push research toward the metabolic and hormonal roots of the disease — insulin resistance, androgen excess, and chronic inflammation — rather than focusing on ovarian cysts,” said Vasilev. Ross agreed and added, “Even though this new name for a long-standing condition affecting women may take some time to associate with PCOS, it is worth the time and patience to better diagnose this whole-body medical phenomenon.”

More: PCOS Is Now PMOS: Doctors Say Name Change Will Improve Diagnosis, Care. This name change was made to reflect the multisystem effects the condition has on the body. Why did PCOS’s name change?

TL;DR: After years of debate, global experts announced that PCOS will now be called PMOS to better reflect the multisystem effects it has on the body.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

8,500 Daily Steps Can Help You Lose Weight and Keep It Off

A new study demonstrates that 8,500 daily steps is the sweet spot for weight management. Stewart Cohen/Getty Images Walking 8,500 steps per day can help people maintain weight loss after an initial lifestyle modification program that includes dietary intervention. The authors of a research analysis say that walking is a simple, attainable activity for most people. Experts emphasize that exercise and diet are the foundations of any successful weight loss strategy. Walking 8,500 steps per day is a simple, effective way to help lose weight and keep it off, according to a new research analysis. Participants who followed an exercise regimen of 8,500 steps a day lost an average of 4.4% of their body weight or nearly 9 pounds during an initial 8-month weight loss phase that included a dietary intervention. During a 10-month follow-up period, participants only regained an average of about 2 pounds. “The findings suggest that higher daily step counts may be associated with improved outcomes in obesity treatment , highlighting a simple and feasible behavior that could be considered within lifestyle interventions,” the researchers wrote. They are presenting their findings at the  European Congress on Obesity ECO 2026  conference in Istanbul, Turkey, from May 12–15. The research was published in the International Journal of Environmental Research and Public Health . Experts not involved in the analysis say the findings reaffirm that exercise is a key component of weight management. “This systematic review and meta-analysis confirmed that higher daily step counts are associated with improved outcomes in obesity treatment,” said  Michael Fredericson , MD, a professor of orthopedic surgery at Stanford University. “These findings support the current recommendations to combine weight loss with exercise for optimal results.” “I believe this is a strong study that highlights the critical role regular exercise plays in both achieving and maintaining a healthy weight ,” added  Mir Ali , MD, a bariatric surgeon, bariatric medicine specialist, and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California. You don’t need 10,000 daily steps for weight loss For their report, researchers analyzed the results of 14 previous studies that included 3,758 adults. The participants had an average age of 53 years and were from several countries, including the United States, the United Kingdom, Australia, and Japan. In those studies, a total of 1,987 participants were enrolled in lifestyle modification programs. The remaining 1,771 participants were in control groups: either on diet-only regimens or given no weight management plan. The lifestyle modification programs combined dietary guidance with recommendations to walk more and track daily steps. Both groups began the study periods walking an average of about 7,200 steps per day. The researchers reported that people in the control group did not increase their daily walking and did not experience weight loss during the initial 8-month phase. The group with life modification programs increased their walking to an average of almost 8,500 steps per day and achieved an average weight loss of nearly 9 pounds during that period. Researchers, however, cautioned that modifications such as calorie reduction were probably the main factor in this short-term weight loss. They said the more significant result was that participants in the life modification programs maintained their higher activity levels, averaging more than 8,200 steps per day during 10-month follow-up periods. Those participants still had an overall average weight loss of about 7 pounds from the start of the study period to the end of the follow-up phase. “On a general level, the significance of this work to public health lies in assessing the association between lifestyle modification programs and weight-related outcomes, given their potential as an affordable way for obesity management,” the researchers wrote. They added that their findings provide evidence for medical professionals to recommend increased daily walking for people trying to lose weight. “During lifestyle modification programs for obesity, practitioners may encourage patients to increase their average daily steps, as this appears to be associated with better clinical outcome,” the researchers wrote. Role of diet and exercise in weight loss Experts say they agreed with the researchers’ conclusions. “Regular exercise, such as walking, helps maintain metabolic rate and burn calories. However, diet remains the most significant component of a healthy lifestyle,” Ali told Healthline. “If an individual consumes excessive calories or poor-quality food, they will likely experience weight gain despite walking 8,500 or more steps per day.” “I emphasize to my patients that the majority of weight loss results from a proper diet , specifically by reducing carbohydrates and sugars while focusing on proteins and vegetables,” he added. ...

More: 8,500 Daily Steps Can Help You Lose Weight and Keep It Off. Experts emphasize that exercise and diet are the foundations of any successful weight loss strategy. Role of diet and exercise in weight loss Experts say they agreed with the researchers’ conclusions.

TL;DR: A new study demonstrates that 8,500 daily steps is the sweet spot for weight management.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Why 'Ballmaxxing' May Be More Dangerous Than You Think

Experts say that “ballmaxxing” may lead to permanent damage to male genitalia. Image Credit: Heathline/Paloma Rincon Studio/GettyImages “Ballmaxxing” is a viral social media phenomenon in which fluids are injected into the testicles to increase their size. Some men are injecting fluids until their testicles become the size of grapefruits. Experts caution that ballmaxxing could cause infection and may result in long-term damage to male genitalia. There is no shortage of “maxxing” trends on social media, from “ looksmaxxing ” to “ fibermaxxing ” to “ sleepmaxxing .” The latest, known as “ballmaxxing,” has men injecting fluids like saline or Surgilube into their testicles to increase their size. Some proponents say that ballmaxxing helped inflate their testicles to the size of grapefruits. But the question on everyone’s mind is, “Why?” Some say that increasing their scrotum size makes them feel more masculine and confident, while others claim they believe women prefer larger testicles. Some have also suggested that ballmaxxing can enhance sexual pleasure and performance. However, saline and Surgilube were not intended for these purposes. Saline is a sterile solution of sodium chloride in water used for medical and health reasons. Surgilube is a sterile, water-soluble surgical lubricant used clinically to facilitate the insertion of medical instruments, catheters, and endoscopes. Both fluids are intended for external medical use and instrument lubrication. Why they’ve been repurposed for ballmaxxing is unclear. Whatever the reason, experts warn that ballmaxxing may cause more harm than good. “Physicians have called ballmaxxing one of the most reckless body modification trends to emerge from male online communities, warning that the temporary size increase often leads to permanent damage,” said Robert Glatter , MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hospital in New York City, and Assistant Professor of Emergency Medicine at Zucker School of Medicine at Hofstra/ Northwell. Healthline spoke with Glatter to learn more about this potentially dangerous trend. This interview has been lightly edited for clarity and length. Is ballmaxxing safe? Glatter: The short answer: The scrotum was not built for this. The area is extremely sensitive and contains delicate structures — including the testicles, blood vessels, and nerves — that are simply not designed to accommodate fluid distension. Specific risks include infection , abscess formation, and cellulitis from the introduction of unregulated fluid outside a medical setting. Pressure from fluid accumulation may also impair blood flow, potentially affecting testicular function — in other words, the very organs someone is trying to “enhance” can be permanently damaged in the process. Most ballmaxxing happens at home with kits bought online, with no sterile field and no trained operator, making sepsis a potential and serious outcome. Others may purchase materials from underground sources, which may contain toxic materials that are not only harmful but also unsterile, increasing the risk of severe infection, sepsis, and the need for surgical intervention with potential permanent disfigurement. Can saline injections cause permanent damage? Glatter: Even medical-grade saline, when injected outside a clinical setting by an untrained individual, carries serious risks. Without proper sterile technique, you are essentially introducing bacteria directly into a warm, enclosed anatomical space — ideal conditions for a rapidly spreading infection, death of tissue, requiring surgical debridement and potentially scrotal removal or resection in the setting of impending necrotizing fasciitis , a potentially fatal condition if not recognized and treated immediately with surgical intervention and aggressive IV antibiotics. Surgilube compounds this further: it is not bioabsorbable, meaning the body cannot break it down and eliminate it, unlike saline, which it can eventually reabsorb. The result can be persistent foreign body reactions, disfigurement, and the need for surgical intervention to remove embedded material. Simply put, it is not intended for injection into body tissue. Injecting a viscous lubricant into scrotal tissue introduces a foreign substance that the body has no mechanism to absorb or clear, raising the risk of granuloma formation (localized area of inflammation), chronic inflammation, and necrosis (tissue destruction) on top of all the infection risks saline alone already poses. What are some proven ways to help enlarge testicles? Glatter: [Safer strategies] involve going to see a board certified urologist for evaluation. Testicular atrophy is a real phenomenon that can accompany aging, low testosterone levels, or certain medical conditions. Evaluation often begins with a testicular ultrasound to check for anatomical issues that could contribute to a smaller testicular size. Next, evaluation of testosterone, FSH (follic...

More: Why 'Ballmaxxing' May Be More Dangerous Than You Think. Experts caution that ballmaxxing could cause infection and may result in long-term damage to male genitalia. Saline is a sterile solution of sodium chloride in water used for medical and health reasons.

TL;DR: Saline is a sterile solution of sodium chloride in water used for medical and health reasons.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

GLP-1 Drugs May Improve Breast Cancer Survival, Lower Risk of Recurrence

A recent study shows that GLP-1 drugs may help improve survival rates in people with breast cancer, obesity, and diabetes. Image Credit: Tatsiana Volkava/Getty Images A recent study found that GLP-1 drugs like Ozempic and Wegovy may improve breast cancer survival and recurrence in those with obesity and related health conditions. The findings suggest that GLP-1 medications were associated with a lower risk of mortality in those with type 2 diabetes than insulin or metformin alone. Experts say that while the findings are promising, more research is still needed. Breast cancer is one of the most common cancers in the United States, accounting for 30% of all new female cancers each year. Individuals with breast cancer that co-occurs with obesity or type 2 diabetes may experience lower survival rates . As GLP-1 medications become a widespread option for the treatment of obesity and type 2 diabetes, a recent study examined their effects on breast cancer outcomes.  The findings, published in JAMA Network Open , show that for those with obesity, type 2 diabetes, or both, the use of GLP-1 drugs helped improve breast cancer survival rates and lower the odds of recurrence.  “[Breast cancer] patients with obesity or pre-existing type 2 diabetes often face more complex breast cancer journeys, ” said lead study author Kristina L. Tatum , PsyD, MS, an instructor in the Department of Social and Behavioral Sciences at the School of Public Health at Virginia Commonwealth University. “ Our findings are encouraging because they suggest that GLP-1RA use may be associated with improved survival and lower recurrence among these patients ,” Tatum told Healthline. “While causation cannot be confirmed from this observational study, the findings provide important data for clinicians and patients with obesity and/or type 2 diabetes to consider as we continue to learn more about the possibilities of GLP-1RA therapies in breast cancer survivorship,” she said. Role of obesity in breast cancer With around 1 in 8 U.S. adults having used a GLP-1, like Ozempic , Wegovy , and Mounjaro , at some point, including 40% with diabetes and 25% with heart disease, the broader health implications of this class of drugs are of increasing interest to researchers.  While the effects of GLP-1 drugs on breast cancer warrant further investigation, the relationship between obesity and cancer may play a role.  In fact, overweight and obesity are known risk factors for breast cancer . Having excess weight also increases the risk of breast cancer recurrence. GLP-1 medications, which are highly effective for weight loss, could therefore help lower these risks, as the new study suggests. Amy Bremner , MD, breast surgical oncologist and medical director of breast surgical oncology at MemorialCare Saddleback Medical Center in Laguna Hills, CA, who wasn’t involved in the study, said the findings were promising. “We know that obesity is well-established as an obesity-associated cancer risk factor. Fat produces estrogen, which promotes certain breast cancer subtypes. By reducing body weight and fat mass, this could potentially reduce recurrence risk,” Bremner told Healthline. Study co-author Bernard F. Fuemmeler , PhD, MPH, professor and Gordon D. Ginder, MD Chair in Cancer Research, said they were encouraged by the findings. “They tell us there is a story here with GLP1 RAs and cancer survivor outcomes that deserves more attention,” he told Healthline. “We plan to continue this work to help build a clearer understanding of these therapies and support providers and cancer survivors as the science continues to evolve,” he said. GLP-1s improve 5- and 10-year breast cancer survival rates The recent study included 841,831 participants with breast cancer and an average age of 69. After taking into account any exclusions, the researchers identified three cohorts: GLP-1 use vs. non-use in people with obesity (BMI of 30 or more) GLP-1 use vs. insulin or metformin in people with type 2 diabetes GLP-1 use vs. sodium-glucose cotransporter 2 inhibitors (SGLT2) in people with type 2 diabetes The 5-year survival probability for those with obesity and breast cancer using a GLP-1 was 97.4%, with the 10-year survival being 96%. This compares to a 5-year survival rate of 93.2% for those not using a GLP-1 and a 10-year survival rate of 88.6%. GLP-1 use was also associated with a lower risk of all-cause mortality in the 10-year follow-up period. “This paper adds to growing evidence that GLP-1 receptor agonists may have an oncologic impact by improving metabolic health,” said Paunel Vukasinov , MD, a dual board certified internist and obesity medicine specialist at Medical Offices of Manhattan. Vukasinov wasn’t involved in the study. “We should use appropriate caution when interpreting these results. This is an observational, retrospective study, not a prospective randomized trial,” Bremner said. “Problems with this type of study include selection bias and confounding variable...

More: GLP-1 Drugs May Improve Breast Cancer Survival, Lower Risk of Recurrence. A recent study shows that GLP-1 drugs may help improve survival rates in people with breast cancer, obesity, and diabetes. GLP-1 medications, which are highly effective for weight loss, could therefore help lower these risks, as the new study suggests.

TL;DR: A recent study shows that GLP-1 drugs may help improve survival rates in people with breast cancer, obesity, and diabetes.

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Healthline May 28, 23:31

Antidepressants During Pregnancy Not Linked to Autism, ADHD. Here’s Why

A large study found no link between SSRI use before or during pregnancy and neurodevelopmental disorders in children. Ekaterina Goncharova/Getty Images A comprehensive review found no causal link between antidepressant use before or during pregnancy and ADHD or autism . Any association of neurodevelopmental disorders appears to be linked to genetic or environmental factors. While antidepressants do have potential risks, it’s important to weigh them against the benefits. Untreated depression is associated with serious risks to both the pregnant person and their baby. Antidepressants have recently come under scrutiny by top U.S. health officials despite their well-established safety and efficacy profiles. A large international study investigated whether antidepressant use before or during pregnancy is linked to neurodevelopmental disorders in children. Researchers from the University of Hong Kong and several global institutions aimed to clarify concerns about whether prenatal exposure to antidepressants raises the risk of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in offspring. The comprehensive review, published online in The Lancet Psychiatry on May 14, found no such association. According to the American College of Obstetricians and Gynecologists (ACOG), around 10% of pregnant people experience depression. Untreated mental illness can lead to risks for both the pregnant person and their baby. Antidepressants, therefore, are commonly prescribed during and after pregnancy. Despite this, Secretary of Health and Human Services Robert F. Kennedy Jr. discourages the use of selective serotonin reuptake inhibitors (SSRIs), a commonly prescribed class of antidepressants. These new findings could help dispel misinformation around antidepressant use during pregnancy. Massive study examines SSRI use during pregnancy The researchers reviewed dozens of previous studies to better understand whether antidepressant use before or during pregnancy was linked to neurodevelopmental conditions in children. They examined outcomes including ADHD, autism spectrum disorder, intellectual disabilities , motor disorders, and speech or language delays. To do this, they searched several major medical research databases and screened nearly 2,000 studies before selecting 37 high quality studies to include in their final analysis. Altogether, the research covered more than 648,000 pregnancies involving antidepressant exposure and nearly 25 million pregnancies without exposure. The researchers combined the findings from these studies and adjusted for factors that could affect the results, such as maternal mental illness, family genetics, and differences in how antidepressant exposure was measured. They also looked at different types of antidepressants , when they were used during pregnancy, dosage levels, and even paternal antidepressant use to help determine whether other underlying factors could explain the findings. To improve transparency and research quality, the study plan was registered in advance through PROSPERO, an international database for systematic reviews. No link between SSRIs and autism, ADHD The analysis found that when mothers used antidepressants during pregnancy, there was a small increase in the chance of their children developing certain neurodevelopmental disorders, such as ADHD and autism. This increased risk was seen whether the antidepressants were used before or during pregnancy. However, the researchers also found that when they carefully considered other factors — like the pregnant person’s mental health history or comparisons between siblings — the link between antidepressant use and these disorders became much weaker or disappeared entirely.  The researchers suggest that the underlying mental health of the parents and other family factors might explain most of the risk, rather than the antidepressant use itself. Further bolstering the idea of the role of genetic or environmental factors, the team also found that the fathers’ antidepressant use during their partner’s pregnancy was linked to a greater chance of ADHD or ASD in children. The study, however, did not find increased risks for other developmental issues , such as intellectual disabilities or speech and language problems. Also, taking higher doses of antidepressants did not appear to increase the risk. Among the different types of antidepressants, only two older medications, amitriptyline and nortriptyline , were consistently linked with higher risks. However, these drugs are less commonly prescribed and often reserved for severe depression.  More commonly prescribed antidepressants, like the SSRIs fluoxetine and sertraline , did not show a clear increased risk once the pregnant person’s mental health was taken into account. Overall, the evidence was not strong and was limited by differences in study methods and remaining uncertainties. The authors also emphasize that untreated depression during pregnancy c...

More: Antidepressants During Pregnancy Not Linked to Autism, ADHD. A large study found no link between SSRI use before or during pregnancy and neurodevelopmental disorders in children. A large international study investigated whether antidepressant use before or during pregnancy is linked to neurodevelopmental disorders in children.

TL;DR: A large study found no link between SSRI use before or during pregnancy and neurodevelopmental disorders in children.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Want to Slow Your Biological Aging? Sleeping 6.4 to 7.8 Hours a Night May Help

Recent research has found an association between sleep duration and biological aging. Image Credit: ArtistGNDphotography/Getty Images A recent study found that too little or too much sleep may speed aging in the brain and other organs. The study used aging clocks to examine associations between sleep and various mental health and medical conditions. The researchers also found a direct link between sleep and late-life depression. Sleep is an important aspect of overall health and emotional well-being. The amount and quality of sleep you get can affect your body in various ways. A recent study published in Nature found that getting too little or too much sleep may speed aging in the brain and other areas of the body. Previous research has linked low sleep to faster brain aging. This study, however, takes that further and shows an association between the amount of sleep you get and the aging of nearly every organ. “Sleep is fundamental for healthy aging and longevity. More importantly, it is potentially modifiable,” said lead study author Junhao Wen , PhD, assistant professor of radiological sciences at Columbia University. “In this study, we measure biological aging clocks across organs to link these clocks with sleep duration,” Wen told Healthline. Sleep duration may speed up aging in brain, organs Chronological age is the number of years you have been alive. Biological age measures how quickly your cells and tissues are aging. Studies like this examine biological aging and the various factors that can affect it. Aging clocks have become increasingly popular in these types of studies. These clocks are scientific, computational models that estimate a person’s biological age and how they are aging faster or slower than their chronological age. These estimates are based on biological data from the individual. Most aging clocks measure age across the whole body. However, organs may age at different rates. The research team behind the study has been instrumental in developing aging clocks for specific organs. These clocks can provide more specific and personalized information to individuals. The study used data from half a million participants in the UK Biobank and machine learning to identify signatures of aging in the organs. The researchers then assessed the relationship between a person’s self-reported sleep duration and their biological age, using 23 aging clocks across 17 organs. The study defined too little sleep as less than 6 hours and too much sleep as more than 8 hours. They found that, in general, people who slept too little or too much showed signs of faster biological aging than those who reported sleeping between 6.4 and 7.8 hours each day. It is important to note that this doesn’t mean that your sleep duration alone causes organs to age faster or slower. However, it does suggest that both too little or too much sleep may play a role in poorer overall health across your body. “Short sleep duration is associated with immune dysregulation and increased systemic inflammation , impairing tissue repair and metabolic homeostasis. It also disrupts glucose regulation and overall energy balance,” said Sarathi Bhattacharyya , MD, pulmonologist, sleep medicine specialist, and medical director of MemorialCare Sleep Disorders Center at Long Beach Medical Center in Long Beach, CA. Bhattacharyya wasn’t involved in the study. “Additionally, insufficient sleep increases sympathetic nervous system activity, which may contribute to accelerated cellular aging across multiple organ systems,” he told Healthline. Bhattacharyya noted that too much sleep can have adverse effects. “Prolonged sleep duration may be associated with similar adverse aging outcomes,” he said. “In many cases, longer sleep may reflect underlying or subclinical pathology that itself contributes to accelerated aging.” How sleep duration affects chronic disease risk The study showed a relationship between sleep and chronic diseases. This suggests that a connection exists beyond brain influence. Too little sleep was associated with brain disorders like depression and anxiety disorders . An association was also found between short sleep and medical conditions, such as: obesity type 2 diabetes hypertension ischemic heart disease heart arrhythmias “Short sleep is often more associated with stress of a busy lifestyle, and anxiety. It can lead to elevated blood pressure , cortisol , and blood glucose levels, which all have detrimental effects over time,” said Alex Dimitriu , MD, a double board certified psychiatry and sleep medicine specialist and founder of Menlo Park Psychiatry & Sleep Medicine in California. Dimitriu wasn’t involved in the study. Too little and too much sleep were also found to be associated with chronic obstructive pulmonary disease (COPD) , asthma , and various gastrointestinal disorders like gastroesophageal reflux disease (GERD) and gastritis . “Longer sleep is associated with depression, but more so [with...

More: Recent research has found an association between sleep duration and biological aging. Bhattacharyya wasn’t involved in the study. An association was also found between short sleep and medical conditions, such as: obesity type 2 diabetes hypertension ischemic heart disease heart arrhythmias “Short sleep is often more associated with stress of a busy lifestyle, and anxiety.

TL;DR: Recent research has found an association between sleep duration and biological aging.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Real Housewives Star Says Breast Cancer Gave Her a ‘Different Type of Strength’

Real Housewives of Miami star Guerdy Abraira says her breast cancer journey has given her a “different type of strength and confidence.” Real Housewives of Miami star Guerdy Abraira. Photos courtesy of Guerdy Abraira\ In March 2023, Real Housewives of Miami star Guerdy Abraira planned to undergo breast augmentation surgery . “My breast was very dense to the point where [my doctor said], ‘We’re not touching anything until you get a mammogram,’” she told Healthline. The mammogram led to a diagnosis of stage 1B estrogen-receptor-positive breast cancer in her left breast. This type of cancer feeds on estrogen to grow. “You feel such a helplessness,” Abraira said. “[There’s] a disbelief that you cannot get over for the first few months, you know? And then … you have to face the reality of it and then figure it out.” In June 2023, Abraira had surgery to remove the cancerous tumor. She then chose to have tissue from the tumor tested with the  Oncotype DX Breast Recurrence Score  to determine the likelihood that the cancer would return, and whether having chemotherapy would benefit her.   The results helped her and her doctor determine that 12 weeks of chemotherapy was appropriate. “[I’m] thankful that I was able to actually utilize this test and be able to see the mathematics of it all,” said Abraira. She also received radiation. “Radiation therapy is typically given to the remaining breast tissue after lumpectomy,” Doreen Agnese , MD, a surgical oncologist, clinical geneticist, and professor at The Ohio State University, told Healthline. Agnese said radiation to the lymph nodes that are not removed in the armpit, above the collarbone, and along the breastbone is also recommended when lymph node involvement is identified, whether after a lumpectomy or a mastectomy. Decisions about chemotherapy and targeted therapies are typically based on the size of the tumor, the status of the lymph nodes, and the receptor status of the tumor. “These factors also help to determine sequencing of therapy. For certain types of tumors (ER positive tumors), genomic testing assays such as Oncotype or Mammaprint can help determine appropriate systemic therapy,” said Agnese. The road to recovery was filled with tough days, but family support helped Abraira recovered from treatment as expected. There were tough days along the way, though. In fact, she recalled not wanting to get chemo on the first day of treatment. “I said, ‘I am not doing this.’ And Russell looked at me, he goes, ‘Oh, yes, you are baby girl; you’re going to do this for me, and you’re going to do this for those boys right outside that door,’” she said. “And that broke me to reset.” She decided to take each moment one at a time. “[If] every morning I wake up, and I feel sluggish, or you know, I’m achy, I’m like, okay, close your eyes…you’re gonna get through this tunnel,” said Abraira. “And that’s how visually I was able to say focus, focus, focus, look, the light is getting brighter.” Breast cancer journey gave her a “different type of strength” “I am very much in the ‘I don’t have time for this phase,’” she said. As a party planning extraordinaire, she said her mentality was always to drop everything and do whatever people needed. “And then came cancer knocking on the door and says, ‘Sweetheart, have a seat and stay humble. It’s time…to test you,’” Abraira said. “[I] definitely feel that it gave me this different type of strength and confidence.” Thinking of herself in two versions—before cancer and after cancer—has also helped her cope. “[Just] now is when I’m starting to post again, old photos of [me] with hair,” she said. “I could not look at those photos of me in the past, cause it just kind of broke me.” She is embracing the new version of herself now. “The new me is actually the person I like better…because I don’t need all the fluff. I don’t need a wig,” she said. She puts more focus on her health post cancer. “My health is of utmost importance. The way I eat is different. I don’t drink the way I used to drink at all…there needs to be a really good reason why I’m drinking at this point,” she said. “[I] really focus on my health and being the best version I can be.” Abraira hopes sharing her story will help others prioritize breast health Using her popularity and platform to spread awareness is rewarding for Abraira “I pick partnerships that make sense for me,” she said. Teaming up with Abbott to share her experience with the Oncotype DX test felt natural to her. “[It] was kind of like, yes, this is amazing cause I can speak on it without looking at notes…It’s coming from [my heart] because I lived it, I experienced it, so I want to help,” Abraira said. The fact that the test applies to women of all cultural backgrounds who qualify to take it makes the partnership even more special to Abraira. “[When] you’re talking about people like my grandmother who’s so superstitious and who just wants to pray the cancer away; ‘No, no, grandma, we’re going to listen to the...

More: Real Housewives Star Says Breast Cancer Gave Her a ‘Different Type of Strength’. She puts more focus on her health post cancer. “My health is of utmost importance.

TL;DR: “My health is of utmost importance.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

GLP-1 Drugs Like Ozempic, Wegovy May Help Lower Blood Pressure

Research shows that GLP-1s may help lower blood pressure levels. Image Credit: Tatiana Maksimova/Getty Images A recent study found that GLP-1 drugs like Ozempic and Wegovy may significantly reduce blood pressure.  The positive results were observed alongside weight loss and independently of it.  The findings add to growing evidence to support the meaningful health benefits of GLP-1 drugs beyond weight loss. Obesity and high blood pressure are closely related chronic health conditions that are of growing concern globally. The two conditions have an interlinking web of causation, where obesity can play a significant role in the development and exacerbation of high blood pressure (hypertension).  A new meta-analysis shows that GLP-1 medications, such as  Ozempic ,  Wegovy , and  Mounjaro , can help significantly reduce blood pressure.   The findings indicate that the reduction in blood pressure was both weight-dependent and independent of weight loss.  The study, recently presented at the  European Congress on Obesity  in Istanbul, Turkey, from May 12–15, has not yet been published in a peer-reviewed journal.  “Given that obesity and hypertension frequently coexist and together substantially increase cardiovascular and kidney risk, these findings support obesity treatment as an important component of blood pressure management and cardiovascular risk reduction,” said lead researcher Marcel Muskiet , MD, PhD, an internist, endocrinologist, and vascular medicine specialist in the Department of Medicine at Leiden University Medical Center (LUMC) in the Netherlands. “Our analyses suggest that the blood pressure benefits of GLP-1 -based therapies are not exclusively driven by weight loss. While weight reduction appears to be the dominant mechanism, these agents may also exert direct renal, vascular, and neurohormonal effects that contribute independently to blood pressure lowering,” Muskiet told Healthline.  GLP-1s significantly lower blood pressure The researchers conducted a meta-analysis of phase 3 clinical trials. They were examining the relationship between weight loss and reduced blood pressure with GLP-1s and multi-hormone receptor modulators (MHRMs). This analysis included 32 phase 3 trials that included 43,618 adults with overweight or obesity . The average age was 54, and the average body mass index (BMI) was 35.5. Around 50% of individuals were female, and 9.2% had type 2 diabetes .  Around 59% of participants were living with high blood pressure , and the average treatment period was 66 weeks. After placebo adjustments were taken into account, the average weight loss was around 10.9%. This was accompanied by a 5.2 mmHg reduction in systolic blood pressure .  The analysis showed that 77% of the variance in blood pressure could be explained by weight loss associated with GLP-1 drugs and MHRMs. This corresponded to a 0.34 mmHg reduction in systolic blood pressure for every 1% of weight loss.  “These findings showed an improvement in hypertension in direct correlation to the amount of weight loss,” said Mir Ali , MD, a bariatric surgeon, bariatric medicine specialist, and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA. Ali wasn’t involved in the research.  “This reinforces the role that obesity plays in hypertension as well as many other health conditions,” Ali told Healthline. The researchers noted that even without weight loss, GLP-1 drugs and MHRMs may help lower blood pressure. This may be due to their ability to relax blood vessels, improve kidney salt handling, and reduce stress signals.  “Though more research is definitely warranted to look at the mechanisms by which GLP-1 medications may work, I have seen some studies indicating that it may be a reduction in chronic inflammation ,” said Ali. “Chronic inflammation can contribute to many health conditions, and obesity is a leading cause of chronic inflammation.” Muskiet explained that the GLP-1 therapies may have various effects independent of weight loss. He said that potential mechanisms include: increased kidney sodium excretion improved endothelial and vascular function reduced arterial stiffness modulation of sympathetic nervous system activity The researchers further noted that their meta-analysis had limitations and that more studies are needed.  “The main message is that obesity treatment and blood pressure management should increasingly be viewed as interconnected rather than separate therapeutic goals,” said Muskiet. “Modern obesity pharmacotherapies are not simply weight-loss agents; they may become an important component of integrated cardiovascular risk reduction strategies in people living with overweight or obesity.” Other health benefits of GLP-1 medications GLP-1 medications were originally developed to help manage type 2 diabetes. They have also become popular tools for weight loss and weight management.  A growing body of evidence suggests that this class of medi...

More: GLP-1 Drugs Like Ozempic, Wegovy May Help Lower Blood Pressure. Research shows that GLP-1s may help lower blood pressure levels. The researchers noted that even without weight loss, GLP-1 drugs and MHRMs may help lower blood pressure.

TL;DR: Research shows that GLP-1s may help lower blood pressure levels.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Wegovy: Semaglutide Reduces Migraine Severity, Especially in Women

A new study found that women using semaglutide had a reduction in their use of triptans, a drug commonly prescribed for migraine. Victor Bordera/Stocksy A study has found that treatment with semaglutide led to reduced triptan usage in women. However, no significant effect was observed in men with overweight or obesity. Experts say reductions in inflammation or intracranial pressure could play a role. Sex-related differences in how the body handles semaglutide also appear to be important. More research is needed before semaglutide can be recommended as a migraine treatment. A recent nationwide study in Denmark has revealed that women who start using semaglutide, a popular medication prescribed for weight loss, may experience a decrease in the need for standard migraine treatments. The researchers found that females using semaglutide had a noticeable reduction in their use of a class of drugs called triptans . The study has not yet been published in a peer-reviewed scientific journal, but was presented at the European Congress on Obesity (ECO2026) from May 12–15. The findings add to a growing interest in the potential benefits of semaglutide for migraine. Another recent study found that GLP-1 medications like semaglutide may help reduce migraine severity . Studying the effects of triptan use after semaglutide Researchers from the University of Southern Denmark collaborated with Novo Nordisk, the pharmaceutical company behind semaglutide (marketed as Wegovy for weight loss and Ozempic for diabetes control), to analyze data from Danish health registries. These registers contain comprehensive health information on the entire population, enabling a detailed examination of medication use patterns. The study focused on adults who began semaglutide treatment for weight management between December 1, 2022, and June 30, 2024. It included nearly 150,000 people who started semaglutide during the study period, of whom about two-thirds were females. For each individual, the researchers tracked their use of triptans — the drugs commonly taken for acute migraine relief — for two years before starting semaglutide and for one year afterward. This approach enabled the researchers to observe changes over time and to compare triptan use before and after semaglutide initiation. The team used statistical models to examine monthly triptan consumption, measured in defined daily doses, among the participants. They also looked at the number of new triptan users during the study and analyzed differences among people who had already been using triptans before starting semaglutide. To better understand who was most affected, the researchers broke down the data by sex, age groups, how consistently people remained on semaglutide, and whether they had previously used preventive migraine medications. Reduced need for migraine drug after starting Wegovy Overall, around 4.6% of the individuals used triptans during the study period. Before beginning semaglutide, it was found that triptan use was on the rise among participants. However, after starting the medication, this trend reversed, and triptan use began to decline gradually over the following year. At the one-year mark, there was a modest but clear reduction in triptan consumption compared to what would have been expected based on previous trends. This decrease was mainly seen in people who were already using triptans before starting semaglutide, suggesting that the drug might reduce the need for migraine relief in those with a history of migraine. There was no significant change in the number of new triptan users, however, indicating that semaglutide does not appear to prevent new cases of migraine from developing. When comparing males and females, the study also found that females experienced an 8% reduction in triptan use after starting semaglutide, whereas males showed no significant change. This sex-specific effect may be linked to differences in how males and females respond to semaglutide, including typically greater weight loss among females. Age also played a role, with the largest reductions in triptan use seen in younger adults aged 18 to 35. Additionally, people who had previously taken preventive migraine medications saw a more pronounced decrease in their need for triptans. The researchers further observed that the changes in triptan use happened gradually rather than immediately after starting semaglutide, suggesting a slow but steady improvement in migraine symptoms over time. Semaglutide may influence factors driving migraine While the exact reasons for these findings are not fully understood, several factors might contribute. Tom Lavin, MD, a board certified surgeon and founder of the telehealth company yourEra , said that inflammation and intracranial pressure may play a role, given how GLP-1 medications function in the body and brain. Lavin wasn’t involved in the study. “GLP‑1 medications like semaglutide reduce inflammation throughout the body, including in the brai...

More: A new study found that women using semaglutide had a reduction in their use of triptans, a drug commonly prescribed for migraine. Another recent study found that GLP-1 medications like semaglutide may help reduce migraine severity . The study focused on adults who began semaglutide treatment for weight management between December 1, 2022, and June 30, 2024.

TL;DR: A new study found that women using semaglutide had a reduction in their use of triptans, a drug commonly prescribed for migraine.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

How GLP-1s Like Ozempic Turn Down ‘Food Noise’ to Help You Lose Weight

GLP-1 drugs may help reduce food cravings, leading to healthier eating habits that contribute to weight loss. Image Credit: Juan Moyano/Stocksy A recent study found that using GLP-1 drugs, such as Ozempic and Mounjaro, can help reduce food cravings. The researchers found that GLP-1 medications can reduce “food noise” better than behavioral therapy alone.  Food noise refers to persistent and intrusive thoughts about food that make healthy eating habits difficult.  The concept of “food noise” has garnered attention since the introduction of GLP-1 drugs like Ozempic , Wegovy , and Mounjaro for weight management. Food noise is defined as intrusive and persistent thoughts about food that can interfere with daily life and make healthy behaviors more difficult.  Most of the evidence suggesting that GLP-1 medications helped quiet food noise was anecdotal — until recently. A new study examined short-term changes in food noise in a digital behavioral weight management program both with and without GLP-1 drugs .  The findings have not yet been published in a peer-reviewed journal, but were presented at the European Congress on Obesity in Istanbul, Turkey, from May 12–15. “Food noise is powerful, so when the noise is less, and the environment is more ‘quiet,’ the individual is less likely to consume foods that may contribute to weight gain,” said Kristin Kirkpatrick , president of KAK Consulting and dietitian at the Cleveland Clinic Department of Wellness & Preventive Medicine in Cleveland, OH. Kirkpatrick wasn’t involved in the study.  “Typically, food noise is the loudest for foods that are often additive in nature, such as ultra-processed foods ,” she told Healthline. “Think candy, cookies, bread-based snacks and meals, snack foods, pizzas, etc. Food noise is not the same as hunger. It’s instead tied to powerful, often intrusive cravings.” GLP-1 drugs help quiet food noise This observational study included 417 adults who were participating in a digital behavioral weight management program. The researchers evaluated a one-month change in food noise using the Food Noise Questionnaire (FNQ) . They then compared outcomes between participants who used GLP-1 medications and those who did not. The FNQ asks five questions and scores each answer on a scale of 0 to 4, for a maximum total score of 20. Users rate the questions on a scale from strongly disagree to strongly agree. FNQ Questions I find myself constantly thinking about food throughout the day. My thoughts about food feel uncontrollable. I spend too much time thinking about food. My thoughts about food have negative effects on me and/or my life. My thoughts about food distract me from what I need to do. Each participant completed a questionnaire as a baseline, then another at a one-month follow-up. The participants were categorized into two groups: those who began a GLP-1 medication at baseline and those who used only the behavioral weight management program . The results showed that those who used a GLP-1 drug alongside the weight management program saw a more significant decrease in food noise at the follow-up than those who did not. “The freedom from food noise is a common benefit I hear from my patients on GLP-1s,” Kirkpatrick said. “In fact, it’s often mentioned to be as impactful as weight loss and blood sugar benefits. I am not surprised by this data as GLP-1 use and reduction of food noise seem to go hand in hand.” Michelle Routhenstein , a preventive cardiology dietitian at EntirelyNourished, said that quieting food noise can lead to healthier habits that extend beyond meals and snacks. Routhenstein wasn’t involved in the study.  “Many of my clients also notice a reduced desire for alcohol and smoking, likely because GLP-1s act on the brain’s reward pathways, not just on appetite,” she told Healthline.  Other tips for quieting food noise There are other ways to help reduce food noise besides GLP-1 medications.  “One of the most important things I encourage my clients to focus on is creating a consistent meal timing pattern with nourishment so the body feels adequately fueled throughout the day,” said Routhenstein. “When the body is deprived of food, food noise can become louder because the body is biologically driven to seek out food and protect against perceived starvation,” she added. Kirkpatrick said that using distraction methods can also help. She gave the following examples:  going for a walk leaving an area that has food present performing another task, such as folding laundry, talking with a friend, or building Legos Other strategies can include getting adequate sleep , avoiding overly strict diets, and increasing your physical activity . Routhenstein said that minimizing ultraprocessed and refined foods, which can drive cravings and reward-seeking behavior, may also help. “Reducing food noise is often about helping the person become adequately nourished rather than relying solely on willpower,” said Routhenstein.

More: How GLP-1s Like Ozempic Turn Down ‘Food Noise’ to Help You Lose Weight. GLP-1 drugs may help reduce food cravings, leading to healthier eating habits that contribute to weight loss. “In fact, it’s often mentioned to be as impactful as weight loss and blood sugar benefits.

TL;DR: GLP-1 drugs may help reduce food cravings, leading to healthier eating habits that contribute to weight loss.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Menopause: Plant-Forward Diets Can Help With Weight Management

Eating more plants and fewer processed foods can help with weight management during menopause. Viktoriya Skorikova/Getty Images A new study found that diets rich in plant foods and low in processed meats and salt may help with menopause weight gain. Plant foods have nutrients linked with better metabolic health and a healthy gut microbiome. Experts recommend starting a plant-forward diet with foods you already enjoy. Weight gain is common during menopause, a life stage accompanied by significant changes in the body. New research sheds light on how diet can influence weight gain and obesity risk during menopause . The study, conducted by researchers from Harvard and the National University of Singapore, tracked eating habits and weight changes during the time surrounding menopause.  The findings suggest that adopting certain healthy dietary patterns, especially those rich in plant foods and low in processed meats and salty snacks, may help females better manage their weight during this transition. The study was published on May 20 in JAMA Network Open . The research offers important insights for women and healthcare providers seeking effective strategies to support metabolic health during midlife and beyond. Examining dietary patterns around menopause The study was based on the Nurses’ Health Study II, a large ongoing research project that began in 1989 and includes female nurses from across the United States. For this particular investigation, the researchers focused on females going through menopause and followed them for about 12 years: six years before and six years after their reported menopause. Over 38,000 females took part. Menopause was defined as the point at which females stopped menstruating for at least one year. Every four years, participants completed detailed food questionnaires that captured their usual intake of various foods. The research team then analyzed these responses to calculate scores for 11 different dietary patterns.  These patterns included well-known diets like the Mediterranean diet , the DASH diet (designed to lower blood pressure), and plant-based diets, as well as newer approaches like the Planetary Health Diet , which emphasizes sustainability and heart health.  They also looked at diets categorized by their effects on insulin and inflammation, as well as the consumption of ultra-processed foods. Participants self-reported their weight every 2 years, and the team calculated the annual weight gain or loss for each woman during the study. They also tracked which females developed obesity during the follow-up period. To ensure accurate results, the researchers accounted for factors like age, race, income, physical activity, smoking, hormone therapy use, and baseline body weight. Plant-forward diets linked to less menopause weight gain The study found that participants’ diets were strongly associated with differences in weight gain and obesity risk during menopause. Those who followed healthier eating patterns — such as plant-based diets, the Mediterranean diet, the DASH diet, and especially the Planetary Health Diet — tended to gain less weight over time compared to those with less healthy diets. Overall, these healthy diets were generally rich in fruits, vegetables, whole grains, nuts, and legumes, and lower in red and processed meats, salty foods, potatoes, and fried snacks like french fries, according to the authors. One particularly important finding was the role of diets that keep insulin levels steady.  The researchers used a score called the Empirical Dietary Index for Hyperinsulinemia (EDIH) to assess how different diets might affect insulin in the body, finding that diets with a low insulin-boosting potential were linked to the smallest weight gain and lowest risk of obesity.  On the other hand, foods that tended to increase insulin levels, such as red and processed meats, salty snacks, and fried potatoes, were associated with more weight gain. Planetary Health Diet best defense against obesity They further noted that the Planetary Health Diet stood out as offering the greatest protection against obesity.  This diet emphasizes sustainable eating by focusing on plant proteins like nuts and legumes, healthy fats, whole grains, and plenty of fruits and vegetables, while limiting red meat and refined carbohydrates.  Females who scored high on the Planetary Health Diet had the lowest risk of obesity throughout the study. Ultra-processed foods led to weight gain The team also observed that consuming ultra-processed foods — like packaged snacks and sugary drinks — was linked to more weight gain and higher obesity risk .  This supports previous studies suggesting that limiting heavily processed foods is beneficial for weight management. Additionally, the research highlighted that not all low-carbohydrate diets are equal.  Those that relied on healthier sources of fats and proteins, such as vegetable proteins and unsaturated fats, seemed to protect against weight gain...

More: Menopause: Plant-Forward Diets Can Help With Weight Management. Eating more plants and fewer processed foods can help with weight management during menopause. New research sheds light on how diet can influence weight gain and obesity risk during menopause .

TL;DR: Eating more plants and fewer processed foods can help with weight management during menopause.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

How Much Exercise Do You Need to Lower Your Risk of Cardiovascular Disease?

Researchers say current aerobic exercise recommendations may not be sufficient to reduce cardiovascular risk. MoMo Productions/Getty Images Researchers say adults may need to quadruple the current weekly exercise recommendations to achieve substantial heart health benefits. Those with lower levels of fitness may need as much as 600 minutes of weekly aerobic activity to lower the risks of heart attack and stroke. Experts say the current recommendation of 150 minutes of exercise per week is a solid baseline, but higher levels of activity may yield greater benefits. A new study suggests that adults should aim for up to 4 times the current recommended amount of aerobic exercise per week for optimal heart health. The researchers say that adults should engage in aerobic exercise for 560–610 minutes per week to achieve a significant reduction in the risk of heart attack and stroke. They note that less fit adults may need to exercise more to achieve the same cardiovascular benefits. The results of the study were published on May 19 in published in the British Journal of Sports Medicine . The American Heart Association (AHA) currently  recommends  that adults get at least 150 minutes per week of moderate-intensity aerobic activity — exercise that gets you breathing harder and raises your heart rate but still allows you to carry on a conversation — such as walking, cycling, and running. The study authors say the standard exercise advice may need to shift and be replaced with personalized targets geared toward an individual’s fitness level. “Current [moderate exercise] guidelines provide a universal but modest safety margin, whereas optimal cardiovascular protection may require substantially higher activity volumes,” the researchers wrote. Experts said the research reaffirms the importance of regular exercise for heart health, but were skeptical about the high weekly targets. “This study reinforces what a large body of prior research has already shown: higher levels of moderate-to-vigorous physical activity and cardiorespiratory fitness are associated with a lower risk of developing heart disease,” said  Keith Diaz , PhD, a professor of behavioral medicine at Columbia University Medical Center in New York City, a certified exercise physiologist, and a volunteer member of the AHA’s Physical Activity Science Committee. Diaz wasn’t involved in the study. “However, I would urge caution in interpreting the specific recommendation that people may need three to four times the current physical activity guidelines to substantially reduce heart disease risk,” Diaz told Healthline. 600 minutes of weekly exercise lowers heart risks by more than 30% To reach their findings, researchers at Macao Polytechnic University in China analyzed data from slightly more than 17,000 participants in the  UK Biobank  study from 2013 to 2015. The average age of the participants was 57 years. About 96% were white, and 56% were female. The subjects wore a device on their wrist for 7 consecutive days to record their typical exercise levels. They also completed a cycle test to measure their estimated maximum oxygen consumption ( VO2 max ). Data on smoking status, alcohol intake , diet, body mass index (BMI) , resting heart rate , and blood pressure were also factored in. The researchers reported that over a follow-up period of almost 8 years, 1,233 cardiovascular events were reported among participants. These included 874 atrial fibrillation, 156 myocardial infarction , 111 heart failure, and 92 stroke events. The researchers stated that adults who met the 150 minutes per week exercise guideline experienced a 8% to 9% reduction in cardiovascular risk. They added that 370 minutes of moderate to vigorous exercise per week was needed for those at the lowest fitness level to achieve a 20% reduction in cardiovascular event risk. Those at the highest fitness level needed 340 minutes per week to achieve the same results. To reduce cardiovascular risk by more than 30%, participants needed to engage in 560 to 610 minutes of moderate-to-vigorous exercise per week. The researchers suggest that the current 150 minutes of exercise per week recommendation provides some protection for heart health, but a higher volume of aerobic activity yields greater benefits. “Collectively, these findings confirm that current guidelines provide a robust universal minimum threshold for cardiovascular protection while offering a quantifiable fitness-stratified prescription matrix as a complementary clinical tool to guide motivated patients from baseline adherence toward greater cardiovascular resilience,” the study authors wrote. Kevin Shah , MD, a cardiologist and program director of Heart Failure Outreach at MemorialCare Heart & Vascular Institute at Long Beach Medical Center in California, wasn’t involved in the study but agreed with the researchers’ conclusions. “The standard recommendation — 150 minutes of moderate to vigorous activity each week — is a solid baseline. But ...

More: How Much Exercise Do You Need to Lower Your Risk of Cardiovascular Disease?. Researchers say current aerobic exercise recommendations may not be sufficient to reduce cardiovascular risk. A new study suggests that adults should aim for up to 4 times the current recommended amount of aerobic exercise per week for optimal heart health.

TL;DR: Researchers say current aerobic exercise recommendations may not be sufficient to reduce cardiovascular risk.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Perimenopause May Be the Ideal Time for Cardiovascular Risk Prevention

Research shows that perimenopause may be the ideal time to adopt lifestyle changes to help lower cardiovascular risks. Image Credit: Aleksandar Nakic/Getty Images A recent study suggests that perimenopause offers a “window of opportunity” for females to reassess cardiovascular risk and prompt lifestyle changes.  The findings show that perimenopausal females may be two times more likely to have lower cardiovascular health scores. According to the study authors, lower cardiovascular health scores may be largely due to high cholesterol and blood sugar levels.  Perimenopause is considered the transitional period leading up to menopause. During this time, the ovaries begin to gradually produce fewer hormones, particularly estrogen.  According to a nationwide analysis, U.S. females experiencing perimenopause are twice as likely to have a low cardiovascular health score than those who are still regularly menstruating.  The findings of this study were recently published in the Journal of the American Heart Association , a peer-reviewed journal of the American Heart Association (AHA). “From a cardiovascular standpoint, perimenopause is a very important time in which there are changing hormone levels, specifically with a declining estrogen level, which can have not only an impact on how one may feel but also on how one’s cardiovascular system is impacted and responds,” said Jossef Amirian , MD, a board certified cardiologist with Manhattan Cardiology in New York. Amirian wasn’t involved in the study.   “The end result is potentially a change in body fat distribution, cholesterol and blood glucose levels, blood pressure, and this can all have an impact on blood flow and circulation as well,” he told Healthline. How perimenopause impacts cardiovascular health The analysis included data from 9,248 females ages 18 to 80 who participated in the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2020.  The researchers used the AHA’s Life’s Essential 8 (LE8)  metrics to measure participants’ cardiovascular health scores, along with other factors. The LE8 scores are scientifically based measures of cardiovascular health as defined by the AHA. The recommendations comprise health behaviors and health factors, including:  diet physical activity tobacco use sleep blood pressure blood sugar levels cholesterol levels body weight Using the LE8 scores, an average of all eight factors on a 100-point scale, the researchers assessed participants’ heart health. The average LE8 score among the participants declined with menopausal status: Premenopausal females (average age of 34): average score of 73.3 Perimenopausal females (average age of 50.5) : average score of 69.1 Postmenopausal females (average age of 60): average score of 63.9. After taking into account the effects of aging, the results showed that perimenopausal females were 76% more likely to have a low cholesterol score, meaning they had higher cholesterol levels. Perimenopausal females were also 83% more likely to have a low score for blood sugar, meaning they had higher glucose levels, when compared to premenopausal females. “During perimenopause, women commonly experience adverse metabolic changes, including worsening lipid profiles, increased insulin resistance , and greater accumulation of visceral adiposity,” said Jennifer Wong , MD, a board certified cardiologist and medical director of noninvasive cardiology at MemorialCare Heart and Vascular Institute at Orange Coast Medical Center in Fountain Valley, CA. Wong wasn’t involved in the study. “These physiologic shifts contribute to an elevated cardiovascular risk profile and may partially explain the higher prevalence of low cardiovascular health scores in this population,” she told Healthline. Perimenopause: A ‘window of opportunity’ for heart health The transitional period of perimenopause marks the beginning of many changes in the female body. It’s also an opportunity to focus on assessment, intervention, and prevention of cardiovascular risk factors.  “Perimenopause is considered a ‘window of opportunity’ because during this time of changing hormones and a changing body, we have an opportunity such that if we reverse modifiable risk factors and improve our blood glucose, blood pressure, and cholesterol panels, we have an opportunity to lower our risk of cardiovascular disease and as such, mitigate our risk of heart attack and stroke ,” said Amirian. Adapting heart-healthy behaviors during perimenopause can significantly improve long-term cardiovascular outcomes and overall health. “Proper and adequate sleep , heart-healthy eating habits , and an exercise regimen focused on aerobic activity and strength training are key, especially at this time in one’s life,” said Amirian.

More: Research shows that perimenopause may be the ideal time to adopt lifestyle changes to help lower cardiovascular risks. Image Credit: Aleksandar Nakic/Getty Images A recent study suggests that perimenopause offers a “window of opportunity” for females to reassess cardiovascular risk and prompt lifestyle changes.

TL;DR: According to the study authors, lower cardiovascular health scores may be largely due to high cholesterol and blood sugar levels.  Perimenopause is considered the transitional period leading up to menopause.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

This Dairy Farmer Was Misdiagnosed with Lyme Disease for Years. It Was Lupus

When dairy farmer Brie Hyde began experiencing chronic fatigue and joint pain, doctors treated her for Lyme disease. After years of worsening symptoms, she was diagnosed with Lupus. Photography courtesy of Brie Hyde As a child, Brie Hyde dreamed of being a veterinarian. “I’ve always been an outdoorsy person, very animal fascinated,” she told Healthline. While attending the University of Vermont, she fell in love with dairy farming and started her own farm in Connecticut in 2004. “I was a first-generation female farmer,” she said. “Farming is crazy active and very strenuous on your body and time, and that’s what completed me. That’s what makes me whole.” However, early on during her farming days, she began experiencing intense hand pain that she initially attributed to the physical demands of her job. “There’s pictures and videos and things that I look back at now, and I was constantly rubbing my hands,” said Hyde. The pain eventually spread to her feet, ankles, knees, and hips, and during the summertime, she developed fevers. At first, doctors attributed her symptoms to Lyme disease , a bacterial infection transmitted from ticks. “So they’d put me on prednisone and antibiotics, and 10 days on prednisone, you’re feeling better. So then it would go away, and I would push through,” she said. Signs and symptoms that lead to a lupus diagnosis Hyde’s symptoms persisted and progressed. “I’d be in the shower, and my feet would be purple,” she said. She also noticed a lacy pattern appearing under her skin and a strange reaction to sunlight. “I would go out in the sun, and it would feel like I was burning from the outside in,” said Hyde. She also experienced extreme fatigue . “The crazy fatigue that I was getting and the pain in my hands had gotten to the point where I was like, ‘This is not right. There’s something not right,’” she said. She went back to her primary care physician, who ordered blood tests. Her doctor noticed Hyde had a high Antinuclear Antibody (ANA) test result and suggested she see a rheumatologist to screen for lupus . “I honestly remember, I said, ‘What the hell is lupus?’” she said. “I had no clue. Not on my radar. No idea what it was.” Her rheumatologist diagnosed her with systemic lupus erythematosus (SLE), the most common form of lupus that affects about 200,000 Americans . Of those 200,000, about 184,000 are females . Hyde’s challenging journey to diagnosis isn’t unique. In fact, research indicates that it takes an average of nearly 6 years for a person to receive an accurate lupus diagnosis. “Symptoms can overlap with those of other conditions and are often present at onset. Combined with test results that vary from person to person, this can make the path to diagnosis complex and far from straightforward,” Susan Manzi, MD, Chair of the Allegheny Health Network Medicine Institute, told Healthline. Even after diagnosis, finding effective treatment can be challenging Hyde’s treatment journey involved a long process of trial and error. Doctors first prescribed prednisone and hydroxychloroquine , a common medication used to treat lupus, but she developed a severe allergic reaction. The next medication made her “violently ill,” while another biologic treatment did nothing to improve her symptoms. As she tried different treatments, lupus slowly altered her daily life and that of her husband and children. “My husband was taking on more, and the kids were taking on more,” Hyde said. “There were definitely changes. I couldn’t be outside in the sun as much as I used to.” At one point, the emotional and physical exhaustion became overwhelming and she hesitated to try more treatment. “I was like, ‘I don’t want to take anything anymore,’” she said. “Either I’m taking too many medications to take the side effects away, or these medications are making me sick and I’m not getting any better.” But her doctor urged her not to stop treatment. “One of the things that’s crazy about lupus is as bad as you feel on the outside, my doctor said, ‘You have to realize what it’s doing inside. You’re trying to save your organs for the long haul,’” said Hyde. That perspective changed how Hyde viewed the disease. In March 2023, her rheumatologist suggested she try Saphnelo infusion. “That was a monumental moment in our lives,” said Hyde. “I remember I called my husband and I was like, ‘I didn’t realize how sick I was until now because I feel better.’” Today, she has regained parts of her old life. She works on the farm, vacations with her children, and participates in the life she once feared she might lose. “I’m able to be a normal person,” Hyde said. How lupus care and management is improving Manzi said newer options like the recently FDA-approved Saphnelo Pen , a self-administered, once-weekly treatment for SLE, bring hope to patients like Hyde. Although she is not currently taking this. On top of standard therapy, Manzi said self-administered biologics will help improve access and convenience of treatment while of...

More: This Dairy Farmer Was Misdiagnosed with Lyme Disease for Years. At first, doctors attributed her symptoms to Lyme disease , a bacterial infection transmitted from ticks. That perspective changed how Hyde viewed the disease.

TL;DR: When dairy farmer Brie Hyde began experiencing chronic fatigue and joint pain, doctors treated her for Lyme disease.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Eating More Watermelon May Help Prevent Heart Disease

Watermelon contains powerful nutrients that may offer protection against cardiovascular disease. Image Credit: J. Anthony/Stocksy Research shows that watermelon may help improve heart health and lower your risk of heart disease. It also shows that this fruit may aid in overall nutrient intake for both adults and children. Individuals who consume more watermelon may have a greater intake of essential nutrients, including fiber, potassium, and vitamin C. Watermelon may also help improve hydration. Nothing says summertime like biting into a cold, juicy slice of watermelon — and turns out it’s actually really good for you. Earlier research found the summer staple may help increase your overall nutrient intake and diet quality. The study authors found that people who consumed watermelon had a higher intake of essential nutrients, including dietary fiber , magnesium , potassium , vitamin C , vitamin A , lycopene , and other carotenoids .  This suggests that watermelon can increase nutrient intake and diet quality in both children and adults, the study authors say. Research from 2025 also found that watermelon may have cardioprotective health effects. This aligns with 2022 research showing that watermelon may help lower blood pressure and improve overall heart health. “Watermelon is a great addition to an overall healthy dietary eating pattern because it provides potassium, lycopene, and citrulline, which synergistically can help support blood pressure and blood flow,” said Michelle Routhenstein , preventive cardiology dietitian at EntirelyNourished. Routhenstein wasn’t involved in any of the studies. Surprising heart health benefits of watermelon The 2025 narrative review noted that watermelon is high in the amino acid L-citrulline . L-citrulline may help lower blood pressure and aid in heart health. While the review notes that the exact cardiovascular benefits of L-citrulline are not fully clear, the authors state that it appears consuming watermelon may aid in the prevention and management of cardiovascular disease . “Watermelon’s impact on blood vessel health appears to be beneficial to overall cardiovascular health. This may be based on compounds that impact nitric oxide production, impacting overall blood vessel health,” said Kristin Kirkpatrick , president of KAK, Consulting, LLC, and a dietitian at the Cleveland Clinic Department of Wellness & Preventive Medicine in Cleveland, Ohio. Kirkpatrick wasn’t involved in the studies. The 2022 research also showed that L-citrulline can help lower blood pressure and arterial stiffness, especially in those with cardiometabolic risk factors. These include traits and lifestyle behaviors that combine to increase your likelihood of developing conditions like type 2 diabetes and cardiovascular disease. “While watermelon is a heart-healthy addition, in order to truly reduce your risk of heart attacks and strokes, it needs to be included within a complete heart-healthy diet,” said Routhenstein. Watermelon nutrition facts Watermelon is high in water, nearly fat-free, and a source of essential vitamins and minerals. Eating watermelon is associated with the following health benefits : lower blood pressure reduced insulin resistance reduced muscle soreness Watermelon is also linked to better digestion, improved skin health, and reduced inflammation. The nutrients in 2/3 cup (100 grams) of raw watermelon, according to the USDA , are: Fat: 0.2 grams Calories: 30 Water: 91.4 grams Protein: 0.61 grams Carbs: 7.55 grams Sugar: 6.2 grams Fiber: 0.4 grams Tips for adding watermelon to your diet For watermelon lovers, a simple slice will do the trick. However, there are other nutritious ways to enjoy this tasty summer treat. Routhenstein shared the following suggestions for maximizing the health benefits of watermelon: blend into smoothies add to a salad (a feta-and-mint classic)  make a watermelon gazpacho pair with nuts or Greek yogurt Kirkpatrick added, “Juice it, add it to cottage cheese, make skewers, grill and serve as a side, or even freeze and make watermelon pops.”

More: Watermelon contains powerful nutrients that may offer protection against cardiovascular disease. Image Credit: J. Anthony/Stocksy Research shows that watermelon may help improve heart health and lower your risk of heart disease. It also shows that this fruit may aid in overall nutrient intake for both adults and children.

TL;DR: Anthony/Stocksy Research shows that watermelon may help improve heart health and lower your risk of heart disease.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Lilly's New Drug Yields Dramatic Weight Loss, Rivaling Bariatric Surgery, GLP-1s

A new experimental weight loss drug from Eli Lilly shows dramatic results that rival current GLP-1 drugs and bariatric surgery. Image Credit: Scott Olson/Getty Images Eli Lilly recently announced phase 3 trial results for a promising new weight loss drug retatrutide.  The dramatic results from the TRIUMPH-1 trial represent the greatest weight loss observed in a medication trial, rivaling current GLP-1 drugs and bariatric surgery. Retatrutide is a triple hormone receptor agonist that activates receptors for glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon. Retatrutide led to significant improvements across various cardiovascular risk factors, including waist circumference, cholesterol, and blood pressure.  Eli Lilly’s new experimental weight loss drug retatrutide showed the greatest weight loss in a medication trial to date. The phase 3 results of the TRIUMPH-1 trial showed the drug yielded up to 28% weight loss, with some participants losing up to 85 pounds. Retatrutide is a triple hormone agonist administered by once-weekly injection. The drug activates glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon, whereas weight loss drugs like Ozempic and Wegovy activate only the GLP-1 receptor. Lilly noted in a press release that at 80 weeks, all the doses of retatrutide “met the primary and key secondary endpoints for obesity, delivering clinically meaningful weight loss.” “TRIUMPH-1 highlights the importance of options and the potential for retatrutide to help people across various stages of their obesity journey,” Kenneth Custer , PhD, executive vice president and president, Lilly Cardiometabolic Health, said in a press release . “Together with Zepbound and Foundayo, retatrutide could build on Lilly’s commitment to match treatments to the needs and preferences of patients.” Experts agreed that retatrutide shows promise as a highly effective first-in-class treatment for obesity. “These results indicate that retatrutide is a promising new drug that appears more effective than currently available medications,” said Mir Ali , MD, bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA. Ali wasn’t involved in the trial.  Lilly’s new drug yields up to 85 pounds weight loss In the TRIUMPH-1 trial, participants were given either 4 mg, 9 mg, or 12 mg of retatrutide.  At the end of 80 weeks, participants on each dose lost the following amount of weight on average: 4 mg: 19% or around 47 lbs 9 mg: 25.9% or about 64 lbs 12 mg: 28.3% or around 70 lbs These numbers compare to participants who received a placebo and lost an average of 2.2%, or about 5.5 lbs.  At 104 weeks, participants with a baseline  body mass index (BMI)  of at least 35 achieved an average weight loss of 30.3% (85 lbs) .  “It was impressive to see that every dose of retatrutide resulted in clinically meaningful weight reduction for nearly all participants, and people with severe obesity on the highest dose lost on average 30% of their body weight over two years,” lead investigator Ania Jastreboff , MD, professor of medicine and pediatrics at the Yale School of Medicine and director of the Yale Obesity Research Center, said in a press release .   “Importantly, treatment with retatrutide not only resulted in robust weight reduction, but also in clear improvements in assessed cardiometabolic health measures. For patients I see in [the] clinic, retatrutide may potentially be a highly impactful future tool to treat their obesity and transform their health trajectory.” Participants also saw significant improvements to certain cardiovascular risk factors, including: waist circumference non-HDL cholesterol triglycerides blood pressure high-sensitivity C-reactive protein (hsCRP) “While this medication has the potential to be the most effective option, long-term studies are not yet available,” Ali told Healthline. “Side-by-side comparisons with currently available medications have yet to be determined. Like all weight loss medications, this drug will require long-term use as obesity is a chronic medical condition. At this point, the biggest hurdles for widespread implementation will be availability and insurance coverage,” he said. Side effects of Lilly’s new weight loss drug The most common side effects of retatrutide among participants were similar to those of other GLP-1 medications :  nausea diarrhea constipation vomiting upper respiratory tract infection A small number of participants also experienced dysesthesia and urinary tract infections (UTIs) . Incidents of dysesthesia and UTIs were generally mild to moderate. The majority of them resolved during treatment, and most participants continued taking retatrutide.

More: Lilly's New Drug Yields Dramatic Weight Loss, Rivaling Bariatric Surgery, GLP-1s. A new experimental weight loss drug from Eli Lilly shows dramatic results that rival current GLP-1 drugs and bariatric surgery. Like all weight loss medications, this drug will require long-term use as obesity is a chronic medical condition.

TL;DR: A new experimental weight loss drug from Eli Lilly shows dramatic results that rival current GLP-1 drugs and bariatric surgery.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

NASCAR's Kyle Busch Dies of Sepsis. These Are the ‘Silent Symptoms’ to Know

NASCAR driver Kyle Busch recently died from sepsis, a deadly condition that may begin with “silent symptoms.” Image credit: Sean Gardner/Getty Images NASCAR driver Kyle Busch died on May 21, 2026, from a severe case of pneumonia that progressed to sepsis. Sepsis is the body’s extreme and potentially life threatening response to an infection. Sepsis is both common and unpredictable, meaning it can be easily missed. Knowing the “silent signs” of sepsis can lead to earlier intervention that may be lifesaving. NASCAR fans were shocked to learn that famed driver Kyle Busch died suddenly and tragically on May 21. He was 41. The two-time NASCAR Cup Series champion died of severe pneumonia that progressed to sepsis , the Busch family announced on May 23. NASCAR described Busch as “a rare talent, one who comes along once in a generation. He was fierce, he was passionate, he was immensely skilled and he cared deeply about the sport and fans,” NASCAR said in a statement . Sepsis is a severe and potentially life threatening illness that can develop when an existing infection triggers an extreme immune system response. According to the Centers for Disease Control and Prevention (CDC) , approximately 1.7 million adults in the United States develop sepsis each year. About 350,000 of these cases lead to hospital death or discharge to a hospice. “Reports indicate that Kyle Busch appeared to be struggling with what seemed like a sinus infection or a cold just two weeks before his death, and had even won a race the weekend prior,” Robert Glatter , MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hospital in New York City, and assistant professor of Emergency Medicine at Zucker School of Medicine at Hofstra/ Northwell, told Healthline. “That rapid reversal — from competing to a fatal crisis — is exactly what makes this progression so dangerous,” he said. Sepsis accounts for over one-third of all hospital deaths. Sepsis can be treated if caught early. Knowing the signs of sepsis can help you advocate for yourself or loved ones. Healthline spoke with Glatter to learn more. This interview has been lightly edited for length and clarity. How can pneumonia progress into sepsis? Glatter: Pneumonia begins as a localized infection. Bacteria, a virus, or fungi take hold in the lung tissue, and the immune system responds with targeted inflammation — swelling, fluid accumulation in tiny air sacs, along with the onset of fever. In most cases, such a response is sufficient, and patients can recover with appropriate therapy. In severe pneumonia, however — particularly when the pathogen is aggressive, or the infectious burden is high — the immune response can escape its local boundaries and spill into the bloodstream. At that moment, the body stops fighting an infection in the lungs and begins mounting a systemic war against itself — inflammatory chemicals flood every organ system, blood vessels leak, microscopic clots form throughout the circulation, and blood pressure collapses.  The kidneys, liver, lungs, and heart also begin to fail — not because the infection has physically spread to each organ, but because the immune system’s runaway cascade is damaging them all simultaneously. When blood pressure fails to respond to treatment, it becomes septic shock , which carries mortality rates exceeding 40% . What kind of infections cause sepsis?   Glatter: Any infection, anywhere in the body, can trigger sepsis if the immune response becomes dysregulated. The most common sources include: Urinary tract infections (UTIs) — these are among the most frequent causes, particularly in older adults, where a UTI dismissed as minor can escalate with alarming speed. Abdominal infections — perforated bowel , appendicitis , or gallbladder infection, allowing gut bacteria direct access to the bloodstream. Skin and soft-tissue infections — cellulitis , infected wounds , or pressure ulcers (bedsores) , especially in people with diabetes or poor circulation . Bloodstream infections — often linked to IV lines, urinary catheters , or surgical procedures that create a direct bacterial route into the blood. Meningitis — an infection of the membranes surrounding the brain, which can trigger rapid septic deterioration. Influenza and COVID-19 — these respiratory infections are capable of causing severe immune dysregulation directly or setting the stage for secondary bacterial pneumonia. Dental abscesses — untreated dental infections have caused fatal sepsis. What are the signs of sepsis? Glatter: Sepsis can mimic many other conditions, which contribute to its lethality. The following signs — especially in combination, and in the context of a known or suspected infection — should prompt immediate emergency evaluation: fever above 38.3°C (101°F) or an abnormally low temperature below 36°C (96.8°F) rapid heart rate (above 90 bpm) or rapid breathing (above 20 breaths per minute) sudden confusion, disorientation, or unusual behavior...

More: Sepsis is the body’s extreme and potentially life threatening response to an infection. According to the Centers for Disease Control and Prevention (CDC) , approximately 1.7 million adults in the United States develop sepsis each year.   Glatter: Any infection, anywhere in the body, can trigger sepsis if the immune response becomes dysregulated.

TL;DR: Sepsis is the body’s extreme and potentially life threatening response to an infection.

Read original at Healthline →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

Colorectal Cancer Screening Guidelines Include New Alternative to Colonoscopy

Healthline Health Conditions Health Conditions All Breast Cancer Cancer Care Caregiving for Alzheimer's Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease (COPD) Digestive Health Ey…

More: Healthline Health Conditions Health Conditions All Breast Cancer Cancer Care Caregiving for Alzheimer's Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease (COPD) Digestive Health Eye Health Heart Health Menopause Mental Health Migraine Multiple Sclerosis (MS) Parkinson’s Disease Psoriasis Rheumatoid Arthritis (RA) Sleep Health Type 2 Diabetes Weight Managemen…

TL;DR: Featured Health News All Medicare 2026 Changes Can 6-6-6 Walking Workout Help You Lose Weight?

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Healthline May 28, 23:31

ER Visits for Tick Bites Highest in Over a Decade. How to Protect Yourself

CDC data show that more people are seeking emergency room treatment for tick bites, which can lead to Lyme disease. Image Credit: Iryna Shepetko/Stocksy Data from the Centers for Disease Control and Prevention (CDC) shows that a rise in tick bites is causing higher-than-usual emergency room (ER) visits. Tick bites can lead to Lyme disease, a bacterial infection that can be difficult to diagnose and treat. Climate change may be partially responsible for the higher tick populations in many regions of the United States. Growing tick populations across the United States are leading to more tick bites. According to the Centers for Disease Control and Prevention (CDC) , tick bites are causing a higher-than-usual number of emergency room (ER) visits. As of April, the Northeast saw the largest increase in tick-related ER visits. These rates are far higher than in other parts of the United States. The Midwest is the second-most-affected region. Tick bites can cause Lyme disease, a bacterial infection that can be difficult to diagnose and treat. “This trend is consistent with a broader pattern of increasing tick-borne disease burden in the United States,” said Robert Glatter , MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hospital and assistant professor of Emergency Medicine at Zucker School of Medicine at Hofstra/ Northwell. “An estimated 400,000–470,000 cases of Lyme disease are now diagnosed annually in the U.S., and this number has been rising over the past two decades. Higher ER visits for tick bites likely reflect both a true increase in tick encounters and growing public awareness of tick-borne illness,” Glatter told Healthline. Tick bites drive rise in ER visits Around 31 million people in the United States are bitten by a tick each year. According to the CDC’s Tick Bite Tracker , visits to the emergency room in many parts of the country are currently higher than usual. All regions, except the South Central areas, reported the highest weekly number of tick bite ER visits since 2017. “Emergency departments in endemic areas should be prepared for a corresponding rise in patients presenting with early Lyme disease and other tick-borne infections during peak season (May through August),” said Glatter. Tick bites can lead to various illnesses, including: Lyme disease Rocky Mountain spotted fever alpha-gal syndrome Lyme disease, in particular, is the most common tick-borne disease in the United States. Symptoms of Lyme disease Lyme disease symptoms can begin 3 to 30 days after a tick bite, making the infection difficult to detect. One of the earliest signs of Lyme disease is a “bull’s-eye” rash known as erythema migrans. This rash occurs at the site of the tick bite. It usually has a central red spot surrounded by a clear area, with a red edge. People with lighter skin may have a rash that’s solid red, while people with darker skin may have a rash that resembles a bruise. It may be warm to the touch, but it’s not painful and doesn’t itch. Other symptoms of stage 1 Lyme disease include: vision changes chills fever sore throat enlarged lymph nodes fatigue muscle aches headaches Causes of shifting Lyme disease cases According to a media briefing by the Bloomberg School of Public Health , one of the main reasons for the growing shift in Lyme disease cases and ER visits due to tick bites is climate change. “There has been a rise in tick activity believed to be related to rising temperatures, resulting in shorter and milder winters. Ticks and the animals they thrive on flourish in these conditions,” said Jonathan Jennings , MD, a board certified internist with Medical Offices of Manhattan. “Naturally, since there is increased tick activity, the risk of Lyme disease and other tick-borne diseases increases proportionally,” he told Healthline. During this briefing, Nicole Baumgarth , DVM, PhD, director of the Lyme and Tickborne Diseases Research and Education Institute at the Johns Hopkins Bloomberg School of Public Health, explained that climate change contributes to the expansion of tick populations. “A changing climate, a warming climate is expanding, the ticks northwards who are now able to overwinter in areas further north and at higher altitudes,” she told Healthline. Glatter agreed, noting that several factors are driving the expansion of tick populations. “Climate change — particularly warming temperatures — accelerates tick development, improves overwinter survival, and extends the geographic range of Ixodes scapularis into previously unaffected northern regions,” he said. Glatter added that other drivers of shifts in tick populations, tick bites, and Lyme disease cases may be due to the recovery of white-tailed deer populations. He described white-tailed deer as “critical hosts” for adult ticks, thereby fueling tick abundance and population growth. “Additionally, suburban development encroaching into wooded areas, habitat fragmentation, and urban greening initiatives...

More: CDC data show that more people are seeking emergency room treatment for tick bites, which can lead to Lyme disease. Symptoms of Lyme disease Lyme disease symptoms can begin 3 to 30 days after a tick bite, making the infection difficult to detect.

TL;DR: CDC data show that more people are seeking emergency room treatment for tick bites, which can lead to Lyme disease.

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Sciencedaily May 28, 23:31

Your gut microbes might be turning fiber into extra calories

ASU scientists found that people whose gut microbes make more methane extract more calories from fiber-rich foods. Methanogens help the microbiome turn fiber into energy by consuming hydrogen and producing methane. Using advanced metabolic chambers, researchers measured how diet and gut chemistry interact, showing that methane may signal efficient digestion. The work could lead to personalized diets based on individual microbiomes.

More: Your gut microbes might be turning fiber into extra calories. ASU scientists found that people whose gut microbes make more methane extract more calories from fiber-rich foods. Using advanced metabolic chambers, researchers measured how diet and gut chemistry interact, showing that methane may signal efficient digestion.

TL;DR: ASU scientists found that people whose gut microbes make more methane extract more calories from fiber-rich foods.

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Sciencedaily May 28, 23:31

Too much screen time may be hurting kids’ hearts

More screen time among children and teens is linked to higher risks of heart and metabolic problems, particularly when combined with insufficient sleep. Danish researchers discovered a measurable rise in cardiometabolic risk scores and a metabolic “fingerprint” in frequent screen users. Experts say better sleep and balanced daily routines can help offset these effects and safeguard lifelong health.

More: More screen time among children and teens is linked to higher risks of heart and metabolic problems, particularly when combined with insufficient sleep. Danish researchers discovered a measurable rise in cardiometabolic risk scores and a metabolic “fingerprint” in frequent screen users.

TL;DR: More screen time among children and teens is linked to higher risks of heart and metabolic problems, particularly when combined with insufficient sleep.

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Sciencedaily May 28, 23:31

Wegovy in a pill? Massive weight loss results revealed

Novo Nordisk’s oral semaglutide 25 mg achieved up to 16.6% weight loss in a landmark study, rivaling injectable Wegovy. The pill also improved cardiovascular risk factors and physical activity levels. With a safety profile consistent with existing treatments, experts see it as a breakthrough for patients preferring oral options.

More: Massive weight loss results revealed. Novo Nordisk’s oral semaglutide 25 mg achieved up to 16.6% weight loss in a landmark study, rivaling injectable Wegovy. The pill also improved cardiovascular risk factors and physical activity levels.

TL;DR: Novo Nordisk’s oral semaglutide 25 mg achieved up to 16.6% weight loss in a landmark study, rivaling injectable Wegovy.

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Sciencedaily May 28, 23:31

The bright colors in your food may be harming your kids

Almost 20% of packaged foods and beverages in the US contain synthetic dyes, often paired with excessive sugar to attract children. These additives have been linked to behavioral issues, yet remain widespread among major brands like Mars and PepsiCo. Experts criticize the FDA for relying on voluntary reform, contrasting it with Europe’s stricter labeling laws. Growing state-level action offers hope for meaningful change.

More: The bright colors in your food may be harming your kids. Almost 20% of packaged foods and beverages in the US contain synthetic dyes, often paired with excessive sugar to attract children. These additives have been linked to behavioral issues, yet remain widespread among major brands like Mars and PepsiCo.

TL;DR: Almost 20% of packaged foods and beverages in the US contain synthetic dyes, often paired with excessive sugar to attract children.

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Sciencedaily May 28, 23:31

Rare desert berry could transform diabetes treatment

An extract from a desert berry used in traditional Chinese medicine restored insulin function and stabilized metabolism in diabetic mice. The findings hint at a powerful natural alternative for holistic diabetes treatment.

More: Rare desert berry could transform diabetes treatment. An extract from a desert berry used in traditional Chinese medicine restored insulin function and stabilized metabolism in diabetic mice. The findings hint at a powerful natural alternative for holistic diabetes treatment.

TL;DR: An extract from a desert berry used in traditional Chinese medicine restored insulin function and stabilized metabolism in diabetic mice.

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Sciencedaily May 28, 23:31

Ultra-processed foods quietly push young adults toward prediabetes

Ultra-processed foods, already known for their links to health problems in adults, are now shown to harm young adults too, disrupting blood sugar regulation long before illness appears. A four-year USC study following 85 participants found that even modest increases in UPF consumption drove up the risk of prediabetes and insulin resistance, two early markers that pave the way for type 2 diabetes.

More: Ultra-processed foods, already known for their links to health problems in adults, are now shown to harm young adults too, disrupting blood sugar regulation long before illness appears. A four-year USC study following 85 participants found that even modest increases in UPF consumption drove up the risk of prediabetes and insulin resistance, two early markers that pave the way…

TL;DR: Ultra-processed foods, already known for their links to health problems in adults, are now shown to harm young adults too, disrupting blood sugar regulation long before illness appears.

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Sciencedaily May 28, 23:31

Global surge in ultra-processed foods sparks urgent health warning

Ultra-processed foods are rapidly becoming a global dietary staple, and new research links them to worsening health outcomes around the world. Scientists say only bold, coordinated policy action can counter corporate influence and shift food systems toward healthier options.

More: Global surge in ultra-processed foods sparks urgent health warning. Ultra-processed foods are rapidly becoming a global dietary staple, and new research links them to worsening health outcomes around the world. Scientists say only bold, coordinated policy action can counter corporate influence and shift food systems toward healthier options.

TL;DR: Ultra-processed foods are rapidly becoming a global dietary staple, and new research links them to worsening health outcomes around the world.

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Sciencedaily May 28, 23:31

Vegan diet beats Mediterranean for weight loss even with potatoes and grains

Participants lost more weight on a low-fat vegan diet than on the Mediterranean diet, largely due to eliminating animal foods and reducing oils and nuts. Increased intake of plant foods, even “unhealthy” ones, was strongly associated with greater weight loss.

More: Vegan diet beats Mediterranean for weight loss even with potatoes and grains. Participants lost more weight on a low-fat vegan diet than on the Mediterranean diet, largely due to eliminating animal foods and reducing oils and nuts. Increased intake of plant foods, even “unhealthy” ones, was strongly associated with greater weight loss.

TL;DR: Participants lost more weight on a low-fat vegan diet than on the Mediterranean diet, largely due to eliminating animal foods and reducing oils and nuts.

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Sciencedaily May 28, 23:31

A common nutrient deficiency may be silently harming young brains

Scientists studying young adults with obesity discovered early indicators of brain stress that resemble patterns seen in cognitive impairment. The group showed higher inflammation, signs of liver strain and elevated neurofilament light chain, a marker of neuron injury. Low choline levels appeared closely tied to these changes. The results hint that early metabolic disruptions may quietly influence the brain long before symptoms emerge.

More: A common nutrient deficiency may be silently harming young brains. Scientists studying young adults with obesity discovered early indicators of brain stress that resemble patterns seen in cognitive impairment. The results hint that early metabolic disruptions may quietly influence the brain long before symptoms emerge.

TL;DR: Scientists studying young adults with obesity discovered early indicators of brain stress that resemble patterns seen in cognitive impairment.

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Sciencedaily May 28, 23:31

Millions are about to choose the wrong Medicare plan

Millions face Medicare decisions each year, but many don’t take advantage of tools that can save them money and stress. Insurance marketing often overshadows unbiased options like SHIP, leaving people unaware of better choices. Comparing real costs—not just premiums—can prevent unpleasant surprises, especially when provider networks or drug rules change. New assistance programs for low-income adults offer valuable help for 2026.

More: Millions are about to choose the wrong Medicare plan. Insurance marketing often overshadows unbiased options like SHIP, leaving people unaware of better choices. New assistance programs for low-income adults offer valuable help for 2026.

TL;DR: Millions face Medicare decisions each year, but many don’t take advantage of tools that can save them money and stress.

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Sciencedaily May 28, 23:31

Most of the world isn’t getting enough omega-3

Most people worldwide aren’t getting enough omega-3, leaving a major gap between scientific recommendations and daily diets. Researchers emphasize the critical role of EPA and DHA across all life stages and point out that food alone often can’t meet needs. The review calls for clearer global guidelines and easier access to sustainable omega-3 sources. It also highlights the challenges different populations face in reaching healthy intake levels.

More: Most of the world isn’t getting enough omega-3. Most people worldwide aren’t getting enough omega-3, leaving a major gap between scientific recommendations and daily diets. It also highlights the challenges different populations face in reaching healthy intake levels.

TL;DR: Most people worldwide aren’t getting enough omega-3, leaving a major gap between scientific recommendations and daily diets.

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Sciencedaily May 28, 23:31

Her food cravings vanished on Mounjaro then roared back

Deep-brain recordings showed that Mounjaro and Zepbound briefly shut down the craving circuits linked to food noise in a patient with severe obesity. Her obsessive thoughts about food disappeared as the medication quieted the nucleus accumbens, the brain’s reward hub.

More: Her food cravings vanished on Mounjaro then roared back. Deep-brain recordings showed that Mounjaro and Zepbound briefly shut down the craving circuits linked to food noise in a patient with severe obesity. Her obsessive thoughts about food disappeared as the medication quieted the nucleus accumbens, the brain’s reward hub.

TL;DR: Deep-brain recordings showed that Mounjaro and Zepbound briefly shut down the craving circuits linked to food noise in a patient with severe obesity.

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Sciencedaily May 28, 23:31

Simple light trick reveals hidden brain pathways in microscopic detail

Microscopic fibers secretly shape how every organ in the body works, yet they’ve been notoriously hard to study—until now. A new imaging technique called ComSLI reveals hidden fiber orientations in stunning detail using only a rotating LED light and simple microscopy equipment. It works on any tissue slide, from fresh samples to those more than a century old, allowing scientists to uncover microstructural changes in disorders like Alzheimer’s and even explore the architecture of muscle, bone, and blood vessels.

More: Microscopic fibers secretly shape how every organ in the body works, yet they’ve been notoriously hard to study—until now. A new imaging technique called ComSLI reveals hidden fiber orientations in stunning detail using only a rotating LED light and simple microscopy equipment.

TL;DR: Microscopic fibers secretly shape how every organ in the body works, yet they’ve been notoriously hard to study—until now.

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Sciencedaily May 28, 23:31

Why ultra-processed foods make teens eat more when they aren’t hungry

A Virginia Tech study shows that ultra-processed foods may influence adolescents differently from slightly older young adults. Participants aged 18 to 21 ate more at a buffet and snacked even when not hungry after two weeks on an ultra-processed diet. Because eating without hunger predicts future weight gain, these findings hint at a heightened vulnerability during late adolescence.

More: Why ultra-processed foods make teens eat more when they aren’t hungry. A Virginia Tech study shows that ultra-processed foods may influence adolescents differently from slightly older young adults. Because eating without hunger predicts future weight gain, these findings hint at a heightened vulnerability during late adolescence.

TL;DR: A Virginia Tech study shows that ultra-processed foods may influence adolescents differently from slightly older young adults.

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Sciencedaily May 28, 23:31

New study shows some plant-based diets may raise heart disease risk

Researchers tracking over 63,000 adults found that high-quality, minimally processed plant foods significantly reduce cardiovascular risk. But when those plant foods are ultra-processed, the advantage disappears—and can even backfire. Some ultra-processed plant diets increased risk by 40%. The study urges a shift toward whole, naturally nutrient-rich plant foods.

More: New study shows some plant-based diets may raise heart disease risk. Researchers tracking over 63,000 adults found that high-quality, minimally processed plant foods significantly reduce cardiovascular risk. The study urges a shift toward whole, naturally nutrient-rich plant foods.

TL;DR: Researchers tracking over 63,000 adults found that high-quality, minimally processed plant foods significantly reduce cardiovascular risk.

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Sciencedaily May 28, 23:31

Sugar-free sweeteners may still be harming your liver

Sorbitol, a popular sugar-free sweetener, may not be as harmless as its label suggests. Researchers found it can be turned into fructose in the liver, triggering effects similar to regular sugar. Gut bacteria can neutralize some of it—but too much sorbitol or glucose can overwhelm that defense. The result: yet another “healthy” sweetener that may stress the liver.

More: Sugar-free sweeteners may still be harming your liver. Researchers found it can be turned into fructose in the liver, triggering effects similar to regular sugar. The result: yet another “healthy” sweetener that may stress the liver.

TL;DR: Researchers found it can be turned into fructose in the liver, triggering effects similar to regular sugar.

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Sciencedaily May 28, 23:31

Is a vegan diet safe for kids? A huge study has answers

A major new meta-analysis finds that vegetarian and vegan diets can support healthy growth in children when properly planned. Kids on plant-based diets often had better heart health markers, including lower “bad” cholesterol, and consumed more fiber and vitamins. But the study also flagged common nutrient gaps—especially vitamin B12 and calcium—without supplementation. Experts say plant-based eating is achievable for kids, but only with careful planning.

More: Is a vegan diet safe for kids? Kids on plant-based diets often had better heart health markers, including lower “bad” cholesterol, and consumed more fiber and vitamins. Experts say plant-based eating is achievable for kids, but only with careful planning.

TL;DR: Kids on plant-based diets often had better heart health markers, including lower “bad” cholesterol, and consumed more fiber and vitamins.

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Sciencedaily May 28, 23:31

Scientists tested intermittent fasting without eating less and found no metabolic benefit

Time-restricted eating has been widely promoted as a simple way to boost metabolic health, but new research paints a more complicated picture. When calorie intake stayed the same, an eight-hour eating window did not improve insulin sensitivity or cardiovascular markers. What did change was the body’s internal clock, which shifted based on meal timing and altered sleep patterns. The results suggest calorie reduction, not the eating window itself, may be the real driver of health benefits.

More: Scientists tested intermittent fasting without eating less and found no metabolic benefit. When calorie intake stayed the same, an eight-hour eating window did not improve insulin sensitivity or cardiovascular markers. The results suggest calorie reduction, not the eating window itself, may be the real driver of health benefits.

TL;DR: Time-restricted eating has been widely promoted as a simple way to boost metabolic health, but new research paints a more complicated picture.

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Sciencedaily May 28, 23:31

Brain scans may finally end the guesswork in depression treatment

Researchers compared a traditional Chinese medicine, Yueju Pill, with a standard antidepressant and found both reduced depression symptoms. However, only Yueju Pill increased a brain-supporting protein associated with mood improvement. Brain imaging showed that unique network patterns—especially in visual regions—could predict who benefited most from Yueju Pill. This opens the door to more personalized depression treatments guided by brain scans.

More: Brain scans may finally end the guesswork in depression treatment. Researchers compared a traditional Chinese medicine, Yueju Pill, with a standard antidepressant and found both reduced depression symptoms. This opens the door to more personalized depression treatments guided by brain scans.

TL;DR: Researchers compared a traditional Chinese medicine, Yueju Pill, with a standard antidepressant and found both reduced depression symptoms.

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Sciencedaily May 28, 23:31

This weight loss option beats Ozempic by 5 times

Bariatric surgery far outperformed GLP-1 weight loss drugs in a new real-world comparison of more than 50,000 patients. Two years after treatment, surgery patients lost about 58 pounds on average, while those using semaglutide or tirzepatide lost roughly 12 pounds. Even patients who stayed on GLP-1 drugs for a full year saw much smaller results than surgical patients. High dropout rates and real-world challenges appear to blunt the drugs’ effectiveness.

More: This weight loss option beats Ozempic by 5 times. Bariatric surgery far outperformed GLP-1 weight loss drugs in a new real-world comparison of more than 50,000 patients. High dropout rates and real-world challenges appear to blunt the drugs’ effectiveness.

TL;DR: Bariatric surgery far outperformed GLP-1 weight loss drugs in a new real-world comparison of more than 50,000 patients.

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Sciencedaily May 28, 23:31

A global cancer surge is underway and the world is not ready

Global cancer cases have surged dramatically, doubling since 1990 and reaching 18.5 million new diagnoses in 2023. Deaths have also climbed to over 10 million a year, with the steepest increases hitting low- and middle-income countries. Without urgent action, researchers project more than 30 million new cases annually by 2050. Alarmingly, around four in ten cancer deaths are tied to preventable risks such as smoking, poor diet, and high blood sugar.

More: A global cancer surge is underway and the world is not ready. Without urgent action, researchers project more than 30 million new cases annually by 2050. Alarmingly, around four in ten cancer deaths are tied to preventable risks such as smoking, poor diet, and high blood sugar.

TL;DR: Alarmingly, around four in ten cancer deaths are tied to preventable risks such as smoking, poor diet, and high blood sugar.

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Sciencedaily May 28, 23:31

MIT’s smart pill confirms you took your medicine

MIT engineers have developed a pill that can wirelessly report when it’s been swallowed. Inside the capsule is a biodegradable antenna that sends a signal within minutes of ingestion, then safely dissolves. The system is designed to work with existing medications and could help doctors track adherence for high-risk patients. Researchers hope it will prevent missed doses that can lead to serious health consequences.

More: MIT’s smart pill confirms you took your medicine. The system is designed to work with existing medications and could help doctors track adherence for high-risk patients. Researchers hope it will prevent missed doses that can lead to serious health consequences.

TL;DR: Researchers hope it will prevent missed doses that can lead to serious health consequences.

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Sciencedaily May 28, 23:31

This new sugar tastes like the real thing without the usual downsides

Scientists at Tufts have found a way to turn common glucose into a rare sugar that tastes almost exactly like table sugar—but with far fewer downsides. Using engineered bacteria as microscopic factories, the team can now produce tagatose efficiently and cheaply, achieving yields far higher than current methods. Tagatose delivers nearly the same sweetness as sugar with significantly fewer calories, minimal impact on blood sugar, and even potential benefits for oral and gut health.

More: This new sugar tastes like the real thing without the usual downsides. Scientists at Tufts have found a way to turn common glucose into a rare sugar that tastes almost exactly like table sugar—but with far fewer downsides.

TL;DR: Tagatose delivers nearly the same sweetness as sugar with significantly fewer calories, minimal impact on blood sugar, and even potential benefits for oral and gut health.

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Sciencedaily May 28, 23:31

Keto diet weight loss may come with a hidden cost

A long-term study found that while a ketogenic diet prevented weight gain, it also triggered major metabolic problems. Mice developed fatty liver disease, abnormal blood fats, and an impaired ability to control blood sugar—especially after reintroducing carbohydrates. Male mice were hit hardest, showing severe liver damage. The results suggest keto’s benefits may come with hidden risks over time.

More: Keto diet weight loss may come with a hidden cost. A long-term study found that while a ketogenic diet prevented weight gain, it also triggered major metabolic problems. Mice developed fatty liver disease, abnormal blood fats, and an impaired ability to control blood sugar—especially after reintroducing carbohydrates.

TL;DR: A long-term study found that while a ketogenic diet prevented weight gain, it also triggered major metabolic problems.

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Sciencedaily May 28, 23:31

These common food preservatives may be linked to cancer

A large French study tracking more than 100,000 people over a decade has found that higher consumption of certain food preservatives—commonly found in processed foods and drinks—is linked to a modestly higher cancer risk. While many preservatives showed no association, several widely used ones, including potassium sorbate, sulfites, sodium nitrite, and potassium nitrate, were tied to increased risks of overall cancer and specific types such as breast and prostate cancer.

More: A large French study tracking more than 100,000 people over a decade has found that higher consumption of certain food preservatives—commonly found in processed foods and drinks—is linked to a modestly higher cancer risk.

TL;DR: A large French study tracking more than 100,000 people over a decade has found that higher consumption of certain food preservatives—commonly found in processed foods and drinks—is linked to a modestly higher cancer risk.

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Sciencedaily May 28, 23:31

The type of carbs you eat may affect dementia risk

Carbohydrates don’t just fuel the body—they may also influence how the brain ages. A large long-term study found that diets high in fast-acting carbs that rapidly raise blood sugar were linked to a higher risk of dementia. People who ate more low-glycemic foods like fruit, legumes, and whole grains had a noticeably lower risk of Alzheimer’s. The quality of carbs, not just the amount, appears to matter for brain health.

More: The type of carbs you eat may affect dementia risk. A large long-term study found that diets high in fast-acting carbs that rapidly raise blood sugar were linked to a higher risk of dementia. People who ate more low-glycemic foods like fruit, legumes, and whole grains had a noticeably lower risk of Alzheimer’s.

TL;DR: A large long-term study found that diets high in fast-acting carbs that rapidly raise blood sugar were linked to a higher risk of dementia.

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Sciencedaily May 28, 23:31

New review finds wild blueberries support heart and gut health

A sweeping scientific review highlights wild blueberries as a standout food for cardiometabolic health. The strongest evidence shows improvements in blood vessel function, with encouraging signs for blood pressure, cholesterol, blood sugar, gut health, and cognition. Researchers suggest these benefits may kick in within hours—or build over weeks—thanks to the berries’ unique mix of polyphenols and fiber.

More: New review finds wild blueberries support heart and gut health. A sweeping scientific review highlights wild blueberries as a standout food for cardiometabolic health. The strongest evidence shows improvements in blood vessel function, with encouraging signs for blood pressure, cholesterol, blood sugar, gut health, and cognition.

TL;DR: The strongest evidence shows improvements in blood vessel function, with encouraging signs for blood pressure, cholesterol, blood sugar, gut health, and cognition.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

A quiet change in everyday foods could save thousands of lives

Lowering salt in everyday foods could quietly save lives. Researchers found that modest sodium reductions in bread, packaged foods, and takeout meals could significantly reduce heart disease and stroke rates in France and the U.K. The key advantage is that people would not need to alter their eating habits at all. Small changes to the food supply could deliver large, long-term health benefits.

More: A quiet change in everyday foods could save thousands of lives. Researchers found that modest sodium reductions in bread, packaged foods, and takeout meals could significantly reduce heart disease and stroke rates in France and the U.K. The key advantage is that people would not need to alter their eating habits at all.

TL;DR: The key advantage is that people would not need to alter their eating habits at all.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

The overlooked nutrition risk of Ozempic and Wegovy

Popular weight-loss drugs like Ozempic and Wegovy can dramatically curb appetite, but experts warn many users are flying blind when it comes to nutrition. New research suggests people taking these medications may not be getting enough guidance on protein, vitamins, and overall diet quality, increasing the risk of muscle loss and nutrient deficiencies.

More: The overlooked nutrition risk of Ozempic and Wegovy. Popular weight-loss drugs like Ozempic and Wegovy can dramatically curb appetite, but experts warn many users are flying blind when it comes to nutrition.

TL;DR: New research suggests people taking these medications may not be getting enough guidance on protein, vitamins, and overall diet quality, increasing the risk of muscle loss and nutrient deficiencies.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

This simple diet shift cut 330 calories a day without smaller meals

People who switch to a fully unprocessed diet don’t just eat differently—they eat smarter. Research from the University of Bristol shows that when people avoid ultra-processed foods, they naturally pile their plates with fruits and vegetables, eating over 50% more food by weight while still consuming hundreds fewer calories each day. This happens because whole foods trigger a kind of built-in “nutritional intelligence,” nudging people toward nutrient-rich, lower-calorie options.

More: This simple diet shift cut 330 calories a day without smaller meals. People who switch to a fully unprocessed diet don’t just eat differently—they eat smarter. Research from the University of Bristol shows that when people avoid ultra-processed foods, they naturally pile their plates with fruits and vegetables, eating over 50% more food by weight while still consuming hundreds…

TL;DR: People who switch to a fully unprocessed diet don’t just eat differently—they eat smarter.

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Sciencedaily May 28, 23:31

Ultra-processed foods linked to 47% higher risk of heart attack and stroke

Ultra-processed foods are everywhere in the American diet, and researchers are finding alarming consequences. Using national health data, scientists found that adults with the highest intake of these foods had a 47% higher risk of heart attack or stroke. The results held even after accounting for age, smoking, and income. Experts say reducing ultra-processed foods could become as important to public health as cutting back on tobacco once was.

More: Ultra-processed foods linked to 47% higher risk of heart attack and stroke. Ultra-processed foods are everywhere in the American diet, and researchers are finding alarming consequences. Using national health data, scientists found that adults with the highest intake of these foods had a 47% higher risk of heart attack or stroke.

TL;DR: Ultra-processed foods are everywhere in the American diet, and researchers are finding alarming consequences.

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Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

Nearly 200,000 people reveal the real key to heart health

A decades-long study of nearly 200,000 adults challenges the low-carb versus low-fat debate. Both eating patterns were tied to lower heart disease risk when they emphasized whole grains, plant-based foods, and healthy fats. Versions filled with refined carbs and animal fats increased risk instead. Quality, not just quantity, appears to make the difference.

More: Nearly 200,000 people reveal the real key to heart health. A decades-long study of nearly 200,000 adults challenges the low-carb versus low-fat debate. Both eating patterns were tied to lower heart disease risk when they emphasized whole grains, plant-based foods, and healthy fats.

TL;DR: Both eating patterns were tied to lower heart disease risk when they emphasized whole grains, plant-based foods, and healthy fats.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

Pecans found to improve cholesterol and boost heart health

A sweeping new scientific review suggests that pecans — America’s native nut — may pack more heart power than many people realize. After analyzing over 20 years of research, scientists found consistent evidence that eating pecans can improve key markers of cardiovascular health, including total cholesterol and “bad” LDL cholesterol, while also supporting antioxidant defenses.

More: Pecans found to improve cholesterol and boost heart health. A sweeping new scientific review suggests that pecans — America’s native nut — may pack more heart power than many people realize. After analyzing over 20 years of research, scientists found consistent evidence that eating pecans can improve key markers of cardiovascular health, including total cholesterol and “bad” L…

TL;DR: After analyzing over 20 years of research, scientists found consistent evidence that eating pecans can improve key markers of cardiovascular health, including total cholesterol and “bad” LDL cholesterol, while also supporting antioxidant defenses.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

Scientists discover why high altitude protects against diabetes

Living at high altitude appears to protect against diabetes, and scientists have finally discovered the reason. When oxygen levels drop, red blood cells switch into a new metabolic mode and absorb large amounts of glucose from the blood. This helps the body cope with thin air while also reducing blood sugar levels. A drug that recreates this effect reversed diabetes in mice, hinting at a powerful new treatment strategy.

More: Scientists discover why high altitude protects against diabetes. When oxygen levels drop, red blood cells switch into a new metabolic mode and absorb large amounts of glucose from the blood. This helps the body cope with thin air while also reducing blood sugar levels.

TL;DR: This helps the body cope with thin air while also reducing blood sugar levels.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

Less sugar as a baby, fewer heart attacks as an adult

People whose sugar intake was restricted before birth and in early childhood had markedly lower rates of heart disease later in life. Compared to those never exposed to rationing, their risks of heart attack, stroke, heart failure, and cardiovascular death were cut by roughly 20–30%.

More: Less sugar as a baby, fewer heart attacks as an adult. People whose sugar intake was restricted before birth and in early childhood had markedly lower rates of heart disease later in life. Compared to those never exposed to rationing, their risks of heart attack, stroke, heart failure, and cardiovascular death were cut by roughly 20–30%.

TL;DR: People whose sugar intake was restricted before birth and in early childhood had markedly lower rates of heart disease later in life.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

Just two days of oatmeal cut bad cholesterol by 10%

Eating nothing but oatmeal for just two days might sound extreme, but it delivered a striking payoff in a new clinical trial. People with metabolic syndrome who followed a short, calorie-reduced oat-based plan saw their harmful LDL cholesterol drop by 10%, along with modest weight loss and lower blood pressure. Even more surprising, the cholesterol benefits were still visible six weeks later.

More: Just two days of oatmeal cut bad cholesterol by 10%. People with metabolic syndrome who followed a short, calorie-reduced oat-based plan saw their harmful LDL cholesterol drop by 10%, along with modest weight loss and lower blood pressure. Even more surprising, the cholesterol benefits were still visible six weeks later.

TL;DR: Eating nothing but oatmeal for just two days might sound extreme, but it delivered a striking payoff in a new clinical trial.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:31

American Heart Association warns 60% of US women will have cardiovascular disease by 2050

Heart disease is on track to tighten its grip on American women. New projections from the American Heart Association warn that over the next 25 years, cardiovascular disease will rise sharply, driven largely by a surge in high blood pressure, diabetes, and obesity. By 2050, nearly 60% of women in the U.S. could have high blood pressure, and close to one in three women ages 22 to 44 may already be living with some form of heart disease.

More: American Heart Association warns 60% of US women will have cardiovascular disease by 2050. New projections from the American Heart Association warn that over the next 25 years, cardiovascular disease will rise sharply, driven largely by a surge in high blood pressure, diabetes, and obesity.

TL;DR: Heart disease is on track to tighten its grip on American women.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Parents’ stress may be quietly driving childhood obesity, Yale study finds

A Yale study found that lowering parent stress can help protect young children from obesity. When parents practiced mindfulness and stress-management skills, their kids showed healthier eating patterns and avoided the weight gain seen in families that only focused on diet and exercise.

More: Parents’ stress may be quietly driving childhood obesity, Yale study finds. A Yale study found that lowering parent stress can help protect young children from obesity. When parents practiced mindfulness and stress-management skills, their kids showed healthier eating patterns and avoided the weight gain seen in families that only focused on diet and exercise.

TL;DR: A Yale study found that lowering parent stress can help protect young children from obesity.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Scientists say this simple diet change could transform your gut health

A growing trend called “fibermaxxing” is putting dietary fiber in the spotlight—and for good reason. Fiber plays a powerful role in keeping the body healthy, from supporting digestion and feeding beneficial gut microbes to helping regulate blood sugar and cholesterol. Researchers say getting enough fiber may even lower the risk of conditions like obesity, diabetes, and certain cancers.

More: Scientists say this simple diet change could transform your gut health. Fiber plays a powerful role in keeping the body healthy, from supporting digestion and feeding beneficial gut microbes to helping regulate blood sugar and cholesterol. Researchers say getting enough fiber may even lower the risk of conditions like obesity, diabetes, and certain cancers.

TL;DR: Researchers say getting enough fiber may even lower the risk of conditions like obesity, diabetes, and certain cancers.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Scientists found a surprising way to make exercise work better

Exercise normally boosts the body’s ability to use oxygen, a key marker of health and longevity — but high blood sugar can block that benefit. Researchers found that a ketogenic diet helped mice normalize blood sugar and dramatically improved how their muscles responded to exercise. Their muscles became better at using oxygen and built more endurance fibers. The results suggest diet and exercise may work together in surprising ways to improve metabolic health.

More: Scientists found a surprising way to make exercise work better. Researchers found that a ketogenic diet helped mice normalize blood sugar and dramatically improved how their muscles responded to exercise. The results suggest diet and exercise may work together in surprising ways to improve metabolic health.

TL;DR: Exercise normally boosts the body’s ability to use oxygen, a key marker of health and longevity — but high blood sugar can block that benefit.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Cutting sweet foods doesn’t reduce cravings or improve health

A new study suggests that eating less sweet food doesn’t make people crave it any less—or improve their health markers. Participants who increased or decreased sweetness in their diets showed no changes in preferences, weight, or disease risk. Many even returned to their old eating habits over time. Researchers say it may be time to rethink guidelines that focus on cutting sweetness instead of reducing sugar and calories.

More: Cutting sweet foods doesn’t reduce cravings or improve health. A new study suggests that eating less sweet food doesn’t make people crave it any less—or improve their health markers. Participants who increased or decreased sweetness in their diets showed no changes in preferences, weight, or disease risk.

TL;DR: A new study suggests that eating less sweet food doesn’t make people crave it any less—or improve their health markers.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

You don’t need to lose weight to reverse prediabetes, study finds

For years, people with prediabetes have been told the same thing: lose weight or risk developing diabetes. But new research flips that idea on its head, showing that blood sugar can return to normal even without shedding pounds. The key isn’t just how much fat you carry—it’s where it’s stored. Harmful fat deep in the abdomen fuels inflammation and disrupts insulin, while fat under the skin can actually support healthier metabolism.

More: You don’t need to lose weight to reverse prediabetes, study finds. For years, people with prediabetes have been told the same thing: lose weight or risk developing diabetes. Harmful fat deep in the abdomen fuels inflammation and disrupts insulin, while fat under the skin can actually support healthier metabolism.

TL;DR: For years, people with prediabetes have been told the same thing: lose weight or risk developing diabetes.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Ultra-processed foods linked to 67% higher risk of heart attack and stroke

Eating large amounts of ultra-processed foods like chips, frozen meals, sugary drinks, and packaged snacks may significantly raise the risk of serious heart problems. In a major U.S. study, people consuming around nine servings per day had a 67% higher risk of heart attacks, strokes, or death from heart disease compared to those eating about one serving. The risk didn’t just jump at high levels either. Each additional daily serving increased the likelihood of these events by more than 5%, even after accounting for calories, overall diet quality, and common health conditions.

More: Ultra-processed foods linked to 67% higher risk of heart attack and stroke. study, people consuming around nine servings per day had a 67% higher risk of heart attacks, strokes, or death from heart disease compared to those eating about one serving.

TL;DR: Eating large amounts of ultra-processed foods like chips, frozen meals, sugary drinks, and packaged snacks may significantly raise the risk of serious heart problems.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

New pill cuts “bad” cholesterol by 60% in major trial

A new pill, enlicitide, reduced LDL (“bad”) cholesterol by about 60% in a large clinical trial, matching the power of injectable therapies. Because it’s taken orally, it could overcome one of the biggest barriers keeping patients from using current treatments. Researchers say many people still don’t reach safe cholesterol levels—even on statins—highlighting the need for better options.

More: New pill cuts “bad” cholesterol by 60% in major trial. A new pill, enlicitide, reduced LDL (“bad”) cholesterol by about 60% in a large clinical trial, matching the power of injectable therapies. Researchers say many people still don’t reach safe cholesterol levels—even on statins—highlighting the need for better options.

TL;DR: Researchers say many people still don’t reach safe cholesterol levels—even on statins—highlighting the need for better options.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Scientists say this simple habit may help you lose more weight

A new study suggests that simplifying your diet by eating the same meals and keeping your calorie intake consistent could help you lose more weight. Researchers found that people who followed predictable eating routines during a 12-week program lost more weight than those who constantly changed what they ate. By reducing daily food decisions, routines may make it easier to stick with healthy habits in a world full of tempting options.

More: Scientists say this simple habit may help you lose more weight. A new study suggests that simplifying your diet by eating the same meals and keeping your calorie intake consistent could help you lose more weight. Researchers found that people who followed predictable eating routines during a 12-week program lost more weight than those who constantly changed what they ate.

TL;DR: A new study suggests that simplifying your diet by eating the same meals and keeping your calorie intake consistent could help you lose more weight.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Hardly anyone uses this surprisingly simple blood pressure fix

Salt substitutes offer a simple, low-cost way to reduce sodium intake and improve blood pressure, yet very few Americans actually use them—even among those who need them most. A large national analysis spanning nearly two decades found that usage remains surprisingly low and has not improved over time. Researchers say this gap represents a major missed opportunity for preventing heart disease and stroke.

More: Hardly anyone uses this surprisingly simple blood pressure fix. Salt substitutes offer a simple, low-cost way to reduce sodium intake and improve blood pressure, yet very few Americans actually use them—even among those who need them most. Researchers say this gap represents a major missed opportunity for preventing heart disease and stroke.

TL;DR: Salt substitutes offer a simple, low-cost way to reduce sodium intake and improve blood pressure, yet very few Americans actually use them—even among those who need them most.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

This simple Japanese eating habit could help you live longer without dieting

Hara hachi bu, a traditional Japanese practice of eating until you’re about 80% full, is gaining attention as a simple yet powerful way to improve health and reshape our relationship with food. Rather than promoting strict dieting, it encourages slowing down, tuning into hunger cues, and eating with awareness and gratitude. Research suggests it may help reduce calorie intake, support healthier food choices, and prevent long-term weight gain.

More: This simple Japanese eating habit could help you live longer without dieting. Hara hachi bu, a traditional Japanese practice of eating until you’re about 80% full, is gaining attention as a simple yet powerful way to improve health and reshape our relationship with food.

TL;DR: Research suggests it may help reduce calorie intake, support healthier food choices, and prevent long-term weight gain.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Two simple eating habits linked to lower weight, study finds

A major study suggests that when you eat could play a key role in staying lean. People who fast longer overnight and start their day with an early breakfast were more likely to have a lower BMI years later. Scientists think this is because eating earlier aligns better with the body’s internal clock. But skipping breakfast as part of intermittent fasting didn’t offer the same advantage—and may even be tied to unhealthy habits.

More: Two simple eating habits linked to lower weight, study finds. A major study suggests that when you eat could play a key role in staying lean. Scientists think this is because eating earlier aligns better with the body’s internal clock.

TL;DR: Scientists think this is because eating earlier aligns better with the body’s internal clock.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Men and women with obesity face very different hidden health risks

New research reveals that obesity affects men and women in surprisingly different ways. Men are more likely to develop harmful abdominal fat and signs of liver stress, while women show higher inflammation and cholesterol levels. These differences could help explain why health risks vary between sexes. Scientists say this could lead to more tailored treatments for obesity.

More: Men and women with obesity face very different hidden health risks. Men are more likely to develop harmful abdominal fat and signs of liver stress, while women show higher inflammation and cholesterol levels. Scientists say this could lead to more tailored treatments for obesity.

TL;DR: New research reveals that obesity affects men and women in surprisingly different ways.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Scientists discover why bread can cause weight gain without extra calories

Bread and other carbohydrate staples may be doing more than just filling plates—they could be quietly reshaping metabolism. In a surprising twist, researchers found that mice strongly preferred carbs like bread, rice, and wheat, abandoning their regular diet entirely. Even without eating more calories, they gained weight and body fat, not because they overate, but because their bodies burned less energy.

More: Scientists discover why bread can cause weight gain without extra calories. In a surprising twist, researchers found that mice strongly preferred carbs like bread, rice, and wheat, abandoning their regular diet entirely. Even without eating more calories, they gained weight and body fat, not because they overate, but because their bodies burned less energy.

TL;DR: Even without eating more calories, they gained weight and body fat, not because they overate, but because their bodies burned less energy.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Can sparkling water boost metabolism and help with weight loss?

Sparkling water is often seen as a simple, healthy drink—but could it also help with weight loss? New research suggests it may slightly boost how the body processes blood sugar and energy. However, the effect is very small, meaning it’s no substitute for diet and exercise.

More: Can sparkling water boost metabolism and help with weight loss?. Sparkling water is often seen as a simple, healthy drink—but could it also help with weight loss? New research suggests it may slightly boost how the body processes blood sugar and energy.

TL;DR: New research suggests it may slightly boost how the body processes blood sugar and energy.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

Scientists discover why Ozempic works better for some people

Some people taking Ozempic-like diabetes drugs may be getting dramatically better results for a surprising reason: why they overeat in the first place. A year-long study in Japan found that people who tend to eat because tempting food looks or smells irresistible were much more likely to lose weight and improve blood sugar levels on GLP-1 medications. But people who eat mainly in response to stress, sadness, or emotional struggles didn’t see the same long-term benefits.

More: Some people taking Ozempic-like diabetes drugs may be getting dramatically better results for a surprising reason: why they overeat in the first place. A year-long study in Japan found that people who tend to eat because tempting food looks or smells irresistible were much more likely to lose weight and improve blood sugar levels on GLP-1 medications.

TL;DR: Some people taking Ozempic-like diabetes drugs may be getting dramatically better results for a surprising reason: why they overeat in the first place.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

New obesity discovery rewrites decades of fat science

Scientists have uncovered a surprising secret hidden inside fat cells that could reshape how we think about obesity and metabolic disease. A protein called HSL, long believed to simply release stored fat when the body needs energy, turns out to have a second job deep inside the nucleus of fat cells—helping keep those cells healthy and balanced. Even more surprising, people and mice missing this protein don’t become obese as expected; instead, they lose fat tissue in a dangerous condition called lipodystrophy.

More: Scientists have uncovered a surprising secret hidden inside fat cells that could reshape how we think about obesity and metabolic disease. A protein called HSL, long believed to simply release stored fat when the body needs energy, turns out to have a second job deep inside the nucleus of fat cells—helping keep those cells healthy and balanced.

TL;DR: Scientists have uncovered a surprising secret hidden inside fat cells that could reshape how we think about obesity and metabolic disease.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Sciencedaily May 28, 23:30

This silent tooth infection could be hurting your whole body

Scientists are uncovering a surprising link between hidden tooth infections and blood sugar problems. Deep infections around tooth roots can create chronic inflammation that spreads through the body and may interfere with insulin function. Studies found that people who underwent root canal treatment often experienced better blood sugar control and reduced inflammation afterward. The research suggests that treating an infected tooth could have benefits far beyond the mouth.

More: This silent tooth infection could be hurting your whole body. Scientists are uncovering a surprising link between hidden tooth infections and blood sugar problems. Studies found that people who underwent root canal treatment often experienced better blood sugar control and reduced inflammation afterward.

TL;DR: Studies found that people who underwent root canal treatment often experienced better blood sugar control and reduced inflammation afterward.

Read original at Sciencedaily →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Food Dive May 28, 14:16

Lab-Grown Coffee and Chocolate Enter Commercial Production

Cell-cultured coffee and chocolate reached commercial scale, using bioreactor-grown plant cells to produce flavor-identical beans without deforestation.

More: The gooey campfire staple is a “significant and growing piece” for the company’s namesake chocolate brand, generating nearly $250 million annually, a top executive said. The frozen snack food manufacturer expects the network changes to save $15 million annually.

TL;DR: Cell-cultured coffee and chocolate reached commercial scale, using bioreactor-grown plant cells to produce flavor-identical beans without deforestation.

Read original at Food Dive →

Further reading: EatRightPubMed NutritionWHO NutritionWikipedia

Nutritionletter May 21, 15:36

Download The Full June 2026 Issue PDF

Health Facts for Men NEWSBITES: Extra protein and aging muscles; muscle strength and longevity The Hidden Toll of Chronic Stress SPECIAL REPORT: Functional Fitness for Everyday Life Tomato Time! FEATURED RECIPE: Classic Bruschetta Ask Tufts Experts: What is kombucha? Myth of the Month: Shop only the perimeter The post Download The Full June 2026 Issue PDF appeared first on Tufts Health & Nutrition Letter .

More: Download The Full June 2026 Issue PDF. Health Facts for Men NEWSBITES: Extra protein and aging muscles; muscle strength and longevity The Hidden Toll of Chronic Stress SPECIAL REPORT: Functional Fitness for Everyday Life Tomato Time! Myth of the Month: Shop only the perimeter The post Download The Full June 2026 Issue PDF appeared first on Tufts Health & Nutrition Letter .

TL;DR: Health Facts for Men NEWSBITES: Extra protein and aging muscles; muscle strength and longevity The Hidden Toll of Chronic Stress SPECIAL REPORT: Functional Fitness for Everyday Life Tomato Time!

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

Health Facts for Men

When it comes to health, men face some distinct risks—and often take fewer preventive steps to address them. Heart disease remains the leading cause of death among men (as well as women), men are more likely to get—and die from—cancer than women, and they are four times more likely than women to die by suicide. […] The post Health Facts for Men appeared first on Tufts Health & Nutrition Letter .

More: Health Facts for Men. Heart disease remains the leading cause of death among men (as well as women), men are more likely to get—and die from—cancer than women, and they are four times more likely than women to die by suicide. […] The post Health Facts for Men appeared first on Tufts Health & Nutrition Letter .

TL;DR: […] The post Health Facts for Men appeared first on Tufts Health & Nutrition Letter .

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

Classic Bruschetta

Steps: 1. Toss together all ingredients and let stand for 30 minutes. 2. Serve at room temperature as an accompaniment for toasted bread (or veggie burgers or pasta). To continue reading this article or issue you must be a paid subscriber. Sign in Subscribe Subscribe to Tufts Health & Nutrition Get the next year of […] The post Classic Bruschetta appeared first on Tufts Health & Nutrition Letter .

More: Toss together all ingredients and let stand for 30 minutes. Serve at room temperature as an accompaniment for toasted bread (or veggie burgers or pasta). Sign in Subscribe Subscribe to Tufts Health & Nutrition Get the next year of […] The post Classic Bruschetta appeared first on Tufts Health & Nutrition Letter .

TL;DR: Sign in Subscribe Subscribe to Tufts Health & Nutrition Get the next year of […] The post Classic Bruschetta appeared first on Tufts Health & Nutrition Letter .

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

High Blood Pressure? Healthy Lifestyle May Lower Cardiometabolic Disease Risk

Nearly half of all U.S. adults have high blood pressure (hypertension). This puts them at increased risk for cardiometabolic diseases like cardiovascular disease and type 2 diabetes. But lifestyle modification may reduce this risk. To continue reading this article or issue you must be a paid subscriber. Sign in Subscribe Subscribe to Tufts Health & […] The post High Blood Pressure? Healthy Lifestyle May Lower Cardiometabolic Disease Risk appeared first on Tufts Health & Nutrition Letter .

More: Nearly half of all U.S. adults have high blood pressure (hypertension). This puts them at increased risk for cardiometabolic diseases like cardiovascular disease and type 2 diabetes. But lifestyle modification may reduce this risk. To continue reading this article or issue you must be a paid subscriber.

TL;DR: Healthy Lifestyle May Lower Cardiometabolic Disease Risk appeared first on Tufts Health & Nutrition Letter .

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

Extra Protein Does Not Preserve Muscle Size or Function with Age

As we age, our bodies get less efficient at replacing tissue lost during normal wear and tear. This is especially true for muscle protein, which results in a loss of muscle mass. A randomized placebo-controlled trial published in May of 2026 in The American Journal of Clinical Nutrition set out to see if increasing protein […] The post Extra Protein Does Not Preserve Muscle Size or Function with Age appeared first on Tufts Health & Nutrition Letter .

More: Extra Protein Does Not Preserve Muscle Size or Function with Age. This is especially true for muscle protein, which results in a loss of muscle mass. A randomized placebo-controlled trial published in May of 2026 in The American Journal of Clinical Nutrition set out to see if increasing protein […] The post Extra Protein Does Not Preserve Muscle Size or Function with Age appea…

TL;DR: This is especially true for muscle protein, which results in a loss of muscle mass.

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

The Hidden Toll of 
Chronic Stress

While stressful situations are a regular part of most people’s lives, chronic or long-term stress can have serious consequences for both physical and mental health. To continue reading this article or issue you must be a paid subscriber. Sign in Subscribe Subscribe to Tufts Health & Nutrition Get the next year of Tufts Health & […] The post The Hidden Toll of 
Chronic Stress appeared first on Tufts Health & Nutrition Letter .

More: While stressful situations are a regular part of most people’s lives, chronic or long-term stress can have serious consequences for both physical and mental health. To continue reading this article or issue you must be a paid subscriber.

TL;DR: While stressful situations are a regular part of most people’s lives, chronic or long-term stress can have serious consequences for both physical and mental health.

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

Tomato Time!

While they’re available all year long, prime tomato season is from July through September. There are more than a thousand tomato varieties in a rainbow of colors and a wide range of shapes and sizes. Tomato 101. Though we eat tomatoes as a vegetable, they are, botanically, a berry! Native to South America, tomatoes were […] The post Tomato Time! appeared first on Tufts Health & Nutrition Letter .

More: While they’re available all year long, prime tomato season is from July through September. Native to South America, tomatoes were […] The post Tomato Time! appeared first on Tufts Health & Nutrition Letter .

TL;DR: appeared first on Tufts Health & Nutrition Letter .

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

Maintenance of Muscle Strength is Associated with Longer Life for Women

Staying strong as you age is important for maintaining independence and overall health. A study published in February of 2026 in the journal JAMA Network Open looked at how muscle strength was associated with longevity in older women. To continue reading this article or issue you must be a paid subscriber. Sign in Subscribe Subscribe […] The post Maintenance of Muscle Strength is Associated with Longer Life for Women appeared first on Tufts Health & Nutrition Letter .

More: Maintenance of Muscle Strength is Associated with Longer Life for Women. Staying strong as you age is important for maintaining independence and overall health. Sign in Subscribe Subscribe […] The post Maintenance of Muscle Strength is Associated with Longer Life for Women appeared first on Tufts Health & Nutrition Letter .

TL;DR: Staying strong as you age is important for maintaining independence and overall health.

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

Kombucha—The Fizzy, Fermented Tea

Q:  Your article on fermented foods (April, 2026) recommended a drink called kombucha. I’ve never heard of it. Can you tell me what it is and where I can find it? A:  Judith C. Thalheimer, RD, LDN, executive editor of Tufts Health & Nutrition Letter, answers: “Kombucha (kuhm-BOO-chuh) is fermented tea that originated as early […] The post Kombucha—The Fizzy, Fermented Tea appeared first on Tufts Health & Nutrition Letter .

More: Kombucha—The Fizzy, Fermented Tea. Q:  Your article on fermented foods (April, 2026) recommended a drink called kombucha. Thalheimer, RD, LDN, executive editor of Tufts Health & Nutrition Letter, answers: “Kombucha (kuhm-BOO-chuh) is fermented tea that originated as early […] The post Kombucha—The Fizzy, Fermented Tea appeared first on Tufts Health & Nutrition Letter .

TL;DR: Q:  Your article on fermented foods (April, 2026) recommended a drink called kombucha.

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutritionletter May 21, 15:35

Functional Fitness for Everyday Life

As we age, our bodies undergo changes that can negatively affect strength, flexibility, mobility, and power. Muscle loss, minor injuries that don’t fully go away, and declining balance, for example, can make everyday tasks more challenging, whether it’s carrying groceries or getting up off the floor. To continue reading this article or issue you must […] The post Functional Fitness for Everyday Life appeared first on Tufts Health & Nutrition Letter .

More: Functional Fitness for Everyday Life. Muscle loss, minor injuries that don’t fully go away, and declining balance, for example, can make everyday tasks more challenging, whether it’s carrying groceries or getting up off the floor.

TL;DR: To continue reading this article or issue you must […] The post Functional Fitness for Everyday Life appeared first on Tufts Health & Nutrition Letter .

Read original at Nutritionletter →

Further reading: PubMed NutritionNutrition.govNutrition.govWikipedia

Nutrition Insight May 6, 00:16

Personalized Nutrition Based on Gut Microbiome Goes Mainstream

Direct-to-consumer gut microbiome testing and personalized meal plans reached 10M users, with clinical studies showing 3x better outcomes than generic diet advice.

More: Boosting NAD+: Tru Niagen and US advertising board clash over supplement claims Gut health champions: Tribiotic supplements, sweetening fibers & ultra-stable postbiotics How Kerry tackles nutrition trends in women’s health, weight loss and longevity Boosting NAD+: Tru Niagen and US advertising board clash over supplement claims Gut health champions: Tribiotic supplements, swee…

TL;DR: Direct-to-consumer gut microbiome testing and personalized meal plans reached 10M users, with clinical studies showing 3x better outcomes than generic diet advice.

Read original at Nutrition Insight →

Further reading: PubMed NutritionWHO NutritionNutrition.govWikipedia